Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Prenylcysteine oxidase-like

Gene

PCYOX1L

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:4 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Probable oxidoreductase.By similarity

<p>This subsection of the ‘Function’ section provides information relevant to cofactors. A cofactor is any non-protein substance required for a protein to be catalytically active. Some cofactors are inorganic, such as the metal atoms zinc, iron, and copper in various oxidation states. Others, such as most vitamins, are organic.<p><a href='/help/cofactor' target='_top'>More...</a></p>Cofactori

FADBy similarity

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

  • prenylcysteine oxidase activity Source: GO_Central

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionOxidoreductase
LigandFAD, Flavoprotein

Enzyme and pathway databases

Reactome - a knowledgebase of biological pathways and processes

More...
Reactomei
R-HSA-114608 Platelet degranulation

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Prenylcysteine oxidase-like (EC:1.8.3.-)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:PCYOX1L
ORF Names:PSEC0105
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 5

Organism-specific databases

Eukaryotic Pathogen Database Resources

More...
EuPathDBi
HostDB:ENSG00000145882.10

Human Gene Nomenclature Database

More...
HGNCi
HGNC:28477 PCYOX1L

neXtProt; the human protein knowledge platform

More...
neXtProti
NX_Q8NBM8

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Secreted

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

Open Targets

More...
OpenTargetsi
ENSG00000145882

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...
PharmGKBi
PA147357517

Polymorphism and mutation databases

BioMuta curated single-nucleotide variation and disease association database

More...
BioMutai
PCYOX1L

Domain mapping of disease mutations (DMDM)

More...
DMDMi
298286841

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section denotes the presence of an N-terminal signal peptide.<p><a href='/help/signal' target='_top'>More...</a></p>Signal peptidei1 – 221 PublicationAdd BLAST22
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_000028028623 – 494Prenylcysteine oxidase-likeAdd BLAST472

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/ptm_processing_section">PTM / Processing</a> section specifies the position and type of each covalently attached glycan group (mono-, di-, or polysaccharide).<p><a href='/help/carbohyd' target='_top'>More...</a></p>Glycosylationi342N-linked (GlcNAc...) asparagineSequence analysis1

Keywords - PTMi

Glycoprotein

Proteomic databases

Encyclopedia of Proteome Dynamics

More...
EPDi
Q8NBM8

jPOST - Japan Proteome Standard Repository/Database

More...
jPOSTi
Q8NBM8

MaxQB - The MaxQuant DataBase

More...
MaxQBi
Q8NBM8

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q8NBM8

PeptideAtlas

More...
PeptideAtlasi
Q8NBM8

PRoteomics IDEntifications database

More...
PRIDEi
Q8NBM8

ProteomicsDB human proteome resource

More...
ProteomicsDBi
72797
72798 [Q8NBM8-2]

PTM databases

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
Q8NBM8

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSG00000145882 Expressed in 215 organ(s), highest expression level in testis

CleanEx database of gene expression profiles

More...
CleanExi
HS_PCYOX1L

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
Q8NBM8 baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
Q8NBM8 HS

Organism-specific databases

Human Protein Atlas

More...
HPAi
HPA037463
HPA038402

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGrid)

More...
BioGridi
122462, 15 interactors

Protein interaction database and analysis system

More...
IntActi
Q8NBM8, 2 interactors

STRING: functional protein association networks

More...
STRINGi
9606.ENSP00000274569

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

Protein Model Portal of the PSI-Nature Structural Biology Knowledgebase

More...
ProteinModelPortali
Q8NBM8

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
Q8NBM8

Database of comparative protein structure models

More...
ModBasei
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the prenylcysteine oxidase family.Curated

Keywords - Domaini

Signal

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
ENOG410IE2Q Eukaryota
ENOG410Y3UN LUCA

Ensembl GeneTree

More...
GeneTreei
ENSGT00390000011206

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
HOG000241149

The HOVERGEN Database of Homologous Vertebrate Genes

More...
HOVERGENi
HBG053532

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q8NBM8

Identification of Orthologs from Complete Genome Data

More...
OMAi
NLFRLWW

Database of Orthologous Groups

More...
OrthoDBi
1114069at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q8NBM8

TreeFam database of animal gene trees

More...
TreeFami
TF329001

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
3.50.50.60, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR036188 FAD/NAD-bd_sf
IPR010795 Prenylcys_lyase
IPR017046 Prenylcysteine_Oxase

The PANTHER Classification System

More...
PANTHERi
PTHR15944 PTHR15944, 1 hit

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF07156 Prenylcys_lyase, 1 hit

PIRSF; a whole-protein classification database

More...
PIRSFi
PIRSF036292 Prenylcysteine_oxidase, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF51905 SSF51905, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>.<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequences (2+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is in its mature form or if it represents the precursor.<p><a href='/help/sequence_processing' target='_top'>More...</a></p>Sequence processingi: The displayed sequence is further processed into a mature form.

This entry describes 2 <p>This subsection of the ‘Sequence’ section lists the alternative protein sequences (isoforms) that can be generated from the same gene by a single or by the combination of up to four biological events (alternative promoter usage, alternative splicing, alternative initiation and ribosomal frameshifting). Additionally, this section gives relevant information on each alternative protein isoform.<p><a href='/help/alternative_products' target='_top'>More...</a></p> isoformsi produced by alternative splicing. AlignAdd to basket

This entry has 2 described isoforms and 2 potential isoforms that are computationally mapped.Show allAlign All

Isoform 1 (identifier: Q8NBM8-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide
        10         20         30         40         50
MARAAPLLAA LTALLAAAAA GGDAPPGKIA VVGAGIGGSA VAHFLQQHFG
60 70 80 90 100
PRVQIDVYEK GTVGGRLATI SVNKQHYESG AASFHSLSLH MQDFVKLLGL
110 120 130 140 150
RHRREVVGRS AIFGGEHFML EETDWYLLNL FRLWWHYGIS FLRLQMWVEE
160 170 180 190 200
VMEKFMRIYK YQAHGYAFSG VEELLYSLGE STFVNMTQHS VAESLLQVGV
210 220 230 240 250
TQRFIDDVVS AVLRASYGQS AAMPAFAGAM SLAGAQGSLW SVEGGNKLVC
260 270 280 290 300
SGLLKLTKAN VIHATVTSVT LHSTEGKALY QVAYENEVGN SSDFYDIVVI
310 320 330 340 350
ATPLHLDNSS SNLTFAGFHP PIDDVQGSFQ PTVVSLVHGY LNSSYFGFPD
360 370 380 390 400
PKLFPFANIL TTDFPSFFCT LDNICPVNIS ASFRRKQPQE AAVWRVQSPK
410 420 430 440 450
PLFRTQLKTL FRSYYSVQTA EWQAHPLYGS RPTLPRFALH DQLFYLNALE
460 470 480 490
WAASSVEVMA VAAKNVALLA YNRWYQDLDK IDQKDLMHKV KTEL
Length:494
Mass (Da):54,646
Last modified:June 15, 2010 - v2
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i18C03FA338D65C9D
GO
Isoform 2 (identifier: Q8NBM8-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     30-82: AVVGAGIGGS...NKQHYESGAA → GAGRTRGGWG...GHHLSQQAAL
     83-494: Missing.

Note: May be produced at very low levels due to a premature stop codon in the mRNA, leading to nonsense-mediated mRNA decay.
Show »
Length:82
Mass (Da):8,344
Checksum:i7AFB20DC59C1DA3B
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 2 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
D6R9J0D6R9J0_HUMAN
Prenylcysteine oxidase-like
PCYOX1L
111Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
E7EVZ5E7EVZ5_HUMAN
Prenylcysteine oxidase-like
PCYOX1L
404Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

<p>This subsection of the ‘Sequence’ section reports difference(s) between the protein sequence shown in the UniProtKB entry and other available protein sequences derived from the same gene.<p><a href='/help/sequence_caution' target='_top'>More...</a></p>Sequence cautioni

The sequence AAH00014 differs from that shown. Reason: Erroneous translation. Wrong choice of CDS.Curated
The sequence AAP97684 differs from that shown. Reason: Erroneous translation. Wrong choice of CDS.Curated
The sequence BAC03391 differs from that shown. Intron retention.Curated

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti338H → P in BAC03391 (Ref. 7) Curated1
Sequence conflicti431R → P in BAC03391 (Ref. 7) Curated1

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section describes natural variant(s) of the protein sequence.<p><a href='/help/variant' target='_top'>More...</a></p>Natural variantiVAR_0311105A → P1 PublicationCorresponds to variant dbSNP:rs2291814Ensembl.1
Natural variantiVAR_050472316A → T. Corresponds to variant dbSNP:rs35552800Ensembl.1
Natural variantiVAR_031111390E → D2 PublicationsCorresponds to variant dbSNP:rs4705336Ensembl.1

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section describes the sequence of naturally occurring alternative protein isoform(s). The changes in the amino acid sequence may be due to alternative splicing, alternative promoter usage, alternative initiation, or ribosomal frameshifting. The information stored in this subsection is used to automatically construct alternative protein sequence(s) for display.<p><a href='/help/var_seq' target='_top'>More...</a></p>Alternative sequenceiVSP_03927130 – 82AVVGA…ESGAA → GAGRTRGGWGWDWGLCCGPF SPAALWTSGADRRVREGNRG WPLGHHLSQQAAL in isoform 2. 2 PublicationsAdd BLAST53
Alternative sequenceiVSP_03927283 – 494Missing in isoform 2. 2 PublicationsAdd BLAST412

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AK075414 mRNA Translation: BAC11604.1
AF451985 mRNA Translation: AAP97684.1 Sequence problems.
AC131025 Genomic DNA No translation available.
BC000014 mRNA Translation: AAH00014.1 Sequence problems.
BC004166 mRNA Translation: AAH04166.3
AL834220 mRNA Translation: CAD38901.2
AK090410 mRNA Translation: BAC03391.1 Sequence problems.

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS4296.1 [Q8NBM8-1]

NCBI Reference Sequences

More...
RefSeqi
NP_001287983.1, NM_001301054.1
NP_001287986.1, NM_001301057.1
NP_076933.3, NM_024028.3 [Q8NBM8-1]

UniGene gene-oriented nucleotide sequence clusters

More...
UniGenei
Hs.644397

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENST00000274569; ENSP00000274569; ENSG00000145882 [Q8NBM8-1]
ENST00000505669; ENSP00000427166; ENSG00000145882 [Q8NBM8-2]
ENST00000511945; ENSP00000426091; ENSG00000145882 [Q8NBM8-2]

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
78991

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
hsa:78991

UCSC genome browser

More...
UCSCi
uc003lqk.3 human [Q8NBM8-1]

Keywords - Coding sequence diversityi

Alternative splicing, Polymorphism

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK075414 mRNA Translation: BAC11604.1
AF451985 mRNA Translation: AAP97684.1 Sequence problems.
AC131025 Genomic DNA No translation available.
BC000014 mRNA Translation: AAH00014.1 Sequence problems.
BC004166 mRNA Translation: AAH04166.3
AL834220 mRNA Translation: CAD38901.2
AK090410 mRNA Translation: BAC03391.1 Sequence problems.
CCDSiCCDS4296.1 [Q8NBM8-1]
RefSeqiNP_001287983.1, NM_001301054.1
NP_001287986.1, NM_001301057.1
NP_076933.3, NM_024028.3 [Q8NBM8-1]
UniGeneiHs.644397

3D structure databases

ProteinModelPortaliQ8NBM8
SMRiQ8NBM8
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi122462, 15 interactors
IntActiQ8NBM8, 2 interactors
STRINGi9606.ENSP00000274569

PTM databases

PhosphoSitePlusiQ8NBM8

Polymorphism and mutation databases

BioMutaiPCYOX1L
DMDMi298286841

Proteomic databases

EPDiQ8NBM8
jPOSTiQ8NBM8
MaxQBiQ8NBM8
PaxDbiQ8NBM8
PeptideAtlasiQ8NBM8
PRIDEiQ8NBM8
ProteomicsDBi72797
72798 [Q8NBM8-2]

Protocols and materials databases

The DNASU plasmid repository

More...
DNASUi
78991
Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000274569; ENSP00000274569; ENSG00000145882 [Q8NBM8-1]
ENST00000505669; ENSP00000427166; ENSG00000145882 [Q8NBM8-2]
ENST00000511945; ENSP00000426091; ENSG00000145882 [Q8NBM8-2]
GeneIDi78991
KEGGihsa:78991
UCSCiuc003lqk.3 human [Q8NBM8-1]

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
78991
EuPathDBiHostDB:ENSG00000145882.10

GeneCards: human genes, protein and diseases

More...
GeneCardsi
PCYOX1L

H-Invitational Database, human transcriptome db

More...
H-InvDBi
HIX0005299
HGNCiHGNC:28477 PCYOX1L
HPAiHPA037463
HPA038402
neXtProtiNX_Q8NBM8
OpenTargetsiENSG00000145882
PharmGKBiPA147357517

GenAtlas: human gene database

More...
GenAtlasi
Search...

Phylogenomic databases

eggNOGiENOG410IE2Q Eukaryota
ENOG410Y3UN LUCA
GeneTreeiENSGT00390000011206
HOGENOMiHOG000241149
HOVERGENiHBG053532
InParanoidiQ8NBM8
OMAiNLFRLWW
OrthoDBi1114069at2759
PhylomeDBiQ8NBM8
TreeFamiTF329001

Enzyme and pathway databases

ReactomeiR-HSA-114608 Platelet degranulation

Miscellaneous databases

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...
ChiTaRSi
PCYOX1L human

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...
GenomeRNAii
78991

Protein Ontology

More...
PROi
PR:Q8NBM8

Gene expression databases

BgeeiENSG00000145882 Expressed in 215 organ(s), highest expression level in testis
CleanExiHS_PCYOX1L
ExpressionAtlasiQ8NBM8 baseline and differential
GenevisibleiQ8NBM8 HS

Family and domain databases

Gene3Di3.50.50.60, 1 hit
InterProiView protein in InterPro
IPR036188 FAD/NAD-bd_sf
IPR010795 Prenylcys_lyase
IPR017046 Prenylcysteine_Oxase
PANTHERiPTHR15944 PTHR15944, 1 hit
PfamiView protein in Pfam
PF07156 Prenylcys_lyase, 1 hit
PIRSFiPIRSF036292 Prenylcysteine_oxidase, 1 hit
SUPFAMiSSF51905 SSF51905, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiPCYXL_HUMAN
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q8NBM8
Secondary accession number(s): Q7Z4S2
, Q8NCY5, Q8NF69, Q9BTE8, Q9BWS3
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: March 20, 2007
Last sequence update: June 15, 2010
Last modified: January 16, 2019
This is version 135 of the entry and version 2 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Complete proteome, Direct protein sequencing, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. Human entries with polymorphisms or disease mutations
    List of human entries with polymorphisms or disease mutations
  3. Human polymorphisms and disease mutations
    Index of human polymorphisms and disease mutations
  4. Human chromosome 5
    Human chromosome 5: entries, gene names and cross-references to MIM
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.

Do not show this banner again