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Entry version 115 (13 Feb 2019)
Sequence version 1 (01 Oct 2002)
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Protein

Transmembrane protein 178A

Gene

TMEM178A

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:3 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at transcript leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Acts as a negative regulator of osteoclast differentiation in basal and inflammatory conditions by regulating TNFSF11-induced Ca (2+) fluxes, thereby controlling the induction of NFATC1.By similarity

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Biological processi

Protein family/group databases

Transport Classification Database

More...
TCDBi
8.A.16.2.8 the ca(+) channel auxiliary subunit Gama1-Gama8 (ccaGama) family

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Transmembrane protein 178A
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:TMEM178A
Synonyms:TMEM178
ORF Names:PSEC0131, UNQ5926/PRO19820
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 2

Organism-specific databases

Eukaryotic Pathogen Database Resources

More...
EuPathDBi
HostDB:ENSG00000152154.10

Human Gene Nomenclature Database

More...
HGNCi
HGNC:28517 TMEM178A

neXtProt; the human protein knowledge platform

More...
neXtProti
NX_Q8NBL3

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular_location_section">'Subcellular location'</a> section describes the subcellular compartment where each non-membrane region of a membrane-spanning protein is found.<p><a href='/help/topo_dom' target='_top'>More...</a></p>Topological domaini26 – 179ExtracellularSequence analysisAdd BLAST154
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular_location_section">'Subcellular location'</a> section describes the extent of a membrane-spanning region of the protein. It denotes the presence of both alpha-helical transmembrane regions and the membrane spanning regions of beta-barrel transmembrane proteins.<p><a href='/help/transmem' target='_top'>More...</a></p>Transmembranei180 – 200HelicalSequence analysisAdd BLAST21
Topological domaini201 – 208CytoplasmicSequence analysis8
Transmembranei209 – 229HelicalSequence analysisAdd BLAST21
Topological domaini230 – 257ExtracellularSequence analysisAdd BLAST28
Transmembranei258 – 278HelicalSequence analysisAdd BLAST21
Topological domaini279 – 297CytoplasmicSequence analysisAdd BLAST19

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Cellular componenti

Endoplasmic reticulum, Membrane

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

DisGeNET

More...
DisGeNETi
130733

Open Targets

More...
OpenTargetsi
ENSG00000152154

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...
PharmGKBi
PA162405994

Polymorphism and mutation databases

BioMuta curated single-nucleotide variation and disease association database

More...
BioMutai
TMEM178A

Domain mapping of disease mutations (DMDM)

More...
DMDMi
74723755

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section denotes the presence of an N-terminal signal peptide.<p><a href='/help/signal' target='_top'>More...</a></p>Signal peptidei1 – 25Sequence analysisAdd BLAST25
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_000028728026 – 297Transmembrane protein 178AAdd BLAST272

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/ptm_processing_section">PTM / Processing</a> section specifies the position and type of each covalently attached glycan group (mono-, di-, or polysaccharide).<p><a href='/help/carbohyd' target='_top'>More...</a></p>Glycosylationi158N-linked (GlcNAc...) asparagineSequence analysis1

Keywords - PTMi

Glycoprotein

Proteomic databases

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q8NBL3

PeptideAtlas

More...
PeptideAtlasi
Q8NBL3

PRoteomics IDEntifications database

More...
PRIDEi
Q8NBL3

ProteomicsDB human proteome resource

More...
ProteomicsDBi
72790
72791 [Q8NBL3-2]

Consortium for Top Down Proteomics

More...
TopDownProteomicsi
Q8NBL3-1 [Q8NBL3-1]

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSG00000152154 Expressed in 156 organ(s), highest expression level in right hemisphere of cerebellum

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
Q8NBL3 HS

Organism-specific databases

Human Protein Atlas

More...
HPAi
HPA052128

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction_section">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function_section">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

Interacts with STIM1.By similarity

Protein-protein interaction databases

Protein interaction database and analysis system

More...
IntActi
Q8NBL3, 1 interactor

STRING: functional protein association networks

More...
STRINGi
9606.ENSP00000281961

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

Protein Model Portal of the PSI-Nature Structural Biology Knowledgebase

More...
ProteinModelPortali
Q8NBL3

Database of comparative protein structure models

More...
ModBasei
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the TMEM178 family.Curated

Keywords - Domaini

Signal, Transmembrane, Transmembrane helix

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
ENOG410IEXN Eukaryota
ENOG410YC3G LUCA

Ensembl GeneTree

More...
GeneTreei
ENSGT00390000015299

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
HOG000063712

The HOVERGEN Database of Homologous Vertebrate Genes

More...
HOVERGENi
HBG070972

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q8NBL3

Identification of Orthologs from Complete Genome Data

More...
OMAi
LPHDVEH

Database of Orthologous Groups

More...
OrthoDBi
1336222at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q8NBL3

TreeFam database of animal gene trees

More...
TreeFami
TF331307

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR004031 PMP22/EMP/MP20/Claudin
IPR039625 T178A/B

The PANTHER Classification System

More...
PANTHERi
PTHR32005 PTHR32005, 1 hit

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF13903 Claudin_2, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>.<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequences (2)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is in its mature form or if it represents the precursor.<p><a href='/help/sequence_processing' target='_top'>More...</a></p>Sequence processingi: The displayed sequence is further processed into a mature form.

This entry describes 2 <p>This subsection of the ‘Sequence’ section lists the alternative protein sequences (isoforms) that can be generated from the same gene by a single or by the combination of up to four biological events (alternative promoter usage, alternative splicing, alternative initiation and ribosomal frameshifting). Additionally, this section gives relevant information on each alternative protein isoform.<p><a href='/help/alternative_products' target='_top'>More...</a></p> isoformsi produced by alternative splicing. AlignAdd to basket
Isoform 1 (identifier: Q8NBL3-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide
        10         20         30         40         50
MEPRALVTAL SLGLSLCSLG LLVTAIFTDH WYETDPRRHK ESCERSRAGA
60 70 80 90 100
DPPDQKNRLM PLSHLPLRDS PPLGRRLLPG GPGRADPESW RSLLGLGGLD
110 120 130 140 150
AECGRPLFAT YSGLWRKCYF LGIDRDIDTL ILKGIAQRCT AIKYHFSQPI
160 170 180 190 200
RLRNIPFNLT KTIQQDEWHL LHLRRITAGF LGMAVAVLLC GCIVATVSFF
210 220 230 240 250
WEESLTQHVA GLLFLMTGIF CTISLCTYAA SISYDLNRLP KLIYSLPADV
260 270 280 290
EHGYSWSIFC AWCSLGFIVA AGGLCIAYPF ISRTKIAQLK SGRDSTV
Length:297
Mass (Da):33,019
Last modified:October 1, 2002 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i757C5C9F7F2CFA53
GO
Isoform 2 (identifier: Q8NBL3-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     66-111: PLRDSPPLGR...ECGRPLFATY → LGPLEEVLLP...SAHPLAKHSF
     112-297: Missing.

Note: No experimental confirmation available.
Show »
Length:111
Mass (Da):12,447
Checksum:iCB052D882F0416D9
GO

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section describes natural variant(s) of the protein sequence.<p><a href='/help/variant' target='_top'>More...</a></p>Natural variantiVAR_032296107L → V1 PublicationCorresponds to variant dbSNP:rs17852679Ensembl.1

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section describes the sequence of naturally occurring alternative protein isoform(s). The changes in the amino acid sequence may be due to alternative splicing, alternative promoter usage, alternative initiation, or ribosomal frameshifting.<p><a href='/help/var_seq' target='_top'>More...</a></p>Alternative sequenceiVSP_02542866 – 111PLRDS…LFATY → LGPLEEVLLPGHRPGHRHPH PERYCAAMHGHQVPLFSAHP LAKHSF in isoform 2. 1 PublicationAdd BLAST46
Alternative sequenceiVSP_025429112 – 297Missing in isoform 2. 1 PublicationAdd BLAST186

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AY358773 mRNA Translation: AAQ89133.1
AK075440 mRNA Translation: BAC11622.1
AC007246 Genomic DNA Translation: AAX93064.1
BC029530 mRNA Translation: AAH29530.1

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS1804.1 [Q8NBL3-1]

NCBI Reference Sequences

More...
RefSeqi
NP_001161431.1, NM_001167959.1
NP_689603.2, NM_152390.2 [Q8NBL3-1]

UniGene gene-oriented nucleotide sequence clusters

More...
UniGenei
Hs.40808

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENST00000281961; ENSP00000281961; ENSG00000152154 [Q8NBL3-1]
ENST00000618232; ENSP00000477622; ENSG00000152154 [Q8NBL3-2]

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
130733

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
hsa:130733

UCSC genome browser

More...
UCSCi
uc002rrt.5 human [Q8NBL3-1]

Keywords - Coding sequence diversityi

Alternative splicing, Polymorphism

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AY358773 mRNA Translation: AAQ89133.1
AK075440 mRNA Translation: BAC11622.1
AC007246 Genomic DNA Translation: AAX93064.1
BC029530 mRNA Translation: AAH29530.1
CCDSiCCDS1804.1 [Q8NBL3-1]
RefSeqiNP_001161431.1, NM_001167959.1
NP_689603.2, NM_152390.2 [Q8NBL3-1]
UniGeneiHs.40808

3D structure databases

ProteinModelPortaliQ8NBL3
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

IntActiQ8NBL3, 1 interactor
STRINGi9606.ENSP00000281961

Protein family/group databases

TCDBi8.A.16.2.8 the ca(+) channel auxiliary subunit Gama1-Gama8 (ccaGama) family

Polymorphism and mutation databases

BioMutaiTMEM178A
DMDMi74723755

Proteomic databases

PaxDbiQ8NBL3
PeptideAtlasiQ8NBL3
PRIDEiQ8NBL3
ProteomicsDBi72790
72791 [Q8NBL3-2]
TopDownProteomicsiQ8NBL3-1 [Q8NBL3-1]

Protocols and materials databases

The DNASU plasmid repository

More...
DNASUi
130733
Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000281961; ENSP00000281961; ENSG00000152154 [Q8NBL3-1]
ENST00000618232; ENSP00000477622; ENSG00000152154 [Q8NBL3-2]
GeneIDi130733
KEGGihsa:130733
UCSCiuc002rrt.5 human [Q8NBL3-1]

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
130733
DisGeNETi130733
EuPathDBiHostDB:ENSG00000152154.10

GeneCards: human genes, protein and diseases

More...
GeneCardsi
TMEM178A
HGNCiHGNC:28517 TMEM178A
HPAiHPA052128
neXtProtiNX_Q8NBL3
OpenTargetsiENSG00000152154
PharmGKBiPA162405994

GenAtlas: human gene database

More...
GenAtlasi
Search...

Phylogenomic databases

eggNOGiENOG410IEXN Eukaryota
ENOG410YC3G LUCA
GeneTreeiENSGT00390000015299
HOGENOMiHOG000063712
HOVERGENiHBG070972
InParanoidiQ8NBL3
OMAiLPHDVEH
OrthoDBi1336222at2759
PhylomeDBiQ8NBL3
TreeFamiTF331307

Miscellaneous databases

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...
GenomeRNAii
130733

Protein Ontology

More...
PROi
PR:Q8NBL3

Gene expression databases

BgeeiENSG00000152154 Expressed in 156 organ(s), highest expression level in right hemisphere of cerebellum
GenevisibleiQ8NBL3 HS

Family and domain databases

InterProiView protein in InterPro
IPR004031 PMP22/EMP/MP20/Claudin
IPR039625 T178A/B
PANTHERiPTHR32005 PTHR32005, 1 hit
PfamiView protein in Pfam
PF13903 Claudin_2, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiT178A_HUMAN
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q8NBL3
Secondary accession number(s): Q6UWI6, Q8N6N4
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: May 15, 2007
Last sequence update: October 1, 2002
Last modified: February 13, 2019
This is version 115 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. Human chromosome 2
    Human chromosome 2: entries, gene names and cross-references to MIM
  3. Human entries with polymorphisms or disease mutations
    List of human entries with polymorphisms or disease mutations
  4. Human polymorphisms and disease mutations
    Index of human polymorphisms and disease mutations
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