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Protein

Transmembrane protein 229B

Gene

TMEM229B

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score: -Experimental evidence at transcript leveli

Names & Taxonomyi

Protein namesi
Recommended name:
Transmembrane protein 229B
Gene namesi
Name:TMEM229B
Synonyms:C14orf83
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 14

Organism-specific databases

EuPathDBiHostDB:ENSG00000198133.8
HGNCiHGNC:20130 TMEM229B
neXtProtiNX_Q8NBD8

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Topological domaini1 – 14CytoplasmicSequence analysisAdd BLAST14
Transmembranei15 – 35HelicalSequence analysisAdd BLAST21
Topological domaini36 – 40ExtracellularSequence analysis5
Transmembranei41 – 61HelicalSequence analysisAdd BLAST21
Topological domaini62 – 73CytoplasmicSequence analysisAdd BLAST12
Transmembranei74 – 94HelicalSequence analysisAdd BLAST21
Topological domaini95 – 109ExtracellularSequence analysisAdd BLAST15
Transmembranei110 – 130HelicalSequence analysisAdd BLAST21
Topological domaini131 – 167CytoplasmicSequence analysisAdd BLAST37

Keywords - Cellular componenti

Membrane

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000198133
PharmGKBiPA165479330

Polymorphism and mutation databases

BioMutaiTMEM229B
DMDMi74730125

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002636811 – 167Transmembrane protein 229BAdd BLAST167

Proteomic databases

PaxDbiQ8NBD8
PRIDEiQ8NBD8
ProteomicsDBi72758
TopDownProteomicsiQ8NBD8

Expressioni

Gene expression databases

BgeeiENSG00000198133
CleanExiHS_C14orf83
ExpressionAtlasiQ8NBD8 baseline and differential
GenevisibleiQ8NBD8 HS

Organism-specific databases

HPAiHPA046562

Interactioni

Protein-protein interaction databases

IntActiQ8NBD8, 38 interactors

Structurei

3D structure databases

ProteinModelPortaliQ8NBD8
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the TMEM229 family.Curated

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiENOG410IH50 Eukaryota
ENOG410ZYMY LUCA
GeneTreeiENSGT00390000010899
HOGENOMiHOG000007583
HOVERGENiHBG055272
InParanoidiQ8NBD8
OMAiLWEFGTG
OrthoDBiEOG091G0V9P
PhylomeDBiQ8NBD8
TreeFamiTF336481

Family and domain databases

InterProiView protein in InterPro
IPR010540 CmpB_TMEM229
PfamiView protein in Pfam
PF06541 ABC_trans_CmpB, 1 hit

Sequencei

Sequence statusi: Complete.

Q8NBD8-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MASAEPLTAL SRWYLYAIHG YFCEVMFTAA WEFVVNLNWK FPGVTSVWAL
60 70 80 90 100
FIYGTSILIV ERMYLRLRGR CPLLLRCLIY TLWTYLWEFT TGFILRQFNA
110 120 130 140 150
CPWDYSQFDF DFMGLITLEY AVPWFCGALI MEQFIIRNTL RLRFDKDAEP
160
GEPSGALALA NGHVKTD
Length:167
Mass (Da):19,531
Last modified:October 1, 2002 - v1
Checksum:i0C7507C6F00F0D85
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK090706 mRNA Translation: BAC03507.1
BC104940 mRNA Translation: AAI04941.1
BC104942 mRNA Translation: AAI04943.1
CCDSiCCDS9783.1
RefSeqiNP_001335471.1, NM_001348542.1
NP_001335472.1, NM_001348543.1
NP_001335473.1, NM_001348544.1
NP_001335475.1, NM_001348546.1
NP_001335476.1, NM_001348547.1
NP_001335477.1, NM_001348548.1
NP_001335478.1, NM_001348549.1
NP_872332.1, NM_182526.2
XP_016876542.1, XM_017021053.1
XP_016876544.1, XM_017021055.1
UniGeneiHs.509707

Genome annotation databases

EnsembliENST00000357461; ENSP00000350050; ENSG00000198133
ENST00000555638; ENSP00000452201; ENSG00000198133
ENST00000557006; ENSP00000451774; ENSG00000198133
GeneIDi161145
KEGGihsa:161145
UCSCiuc001xjj.2 human

Similar proteinsi

Entry informationi

Entry nameiT229B_HUMAN
AccessioniPrimary (citable) accession number: Q8NBD8
Entry historyiIntegrated into UniProtKB/Swiss-Prot: December 12, 2006
Last sequence update: October 1, 2002
Last modified: July 18, 2018
This is version 101 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Human chromosome 14
    Human chromosome 14: entries, gene names and cross-references to MIM
  2. SIMILARITY comments
    Index of protein domains and families
  3. Uncharacterized protein families (UPF)
    List of uncharacterized protein family (UPF) entries

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