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Protein

Uncharacterized protein C20orf203

Gene

C20orf203

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

Miscellaneous

Originated from non-coding DNA sequences (insertion of repeat elements especially Alu). Seems to exist only in human.

Names & Taxonomyi

Protein namesi
Recommended name:
Uncharacterized protein C20orf203
Gene namesi
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 20

Organism-specific databases

HGNCiHGNC:26592 C20orf203
neXtProtiNX_Q8NBC4

Subcellular locationi

Keywords - Cellular componenti

Cytoplasm

Pathology & Biotechi

Organism-specific databases

DisGeNETi284805
OpenTargetsiENSG00000198547
PharmGKBiPA165392347

Polymorphism and mutation databases

BioMutaiC20orf203

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00003945011 – 194Uncharacterized protein C20orf203Add BLAST194

Proteomic databases

PRIDEiQ8NBC4
ProteomicsDBi72757

Expressioni

Tissue specificityi

Expressed most abundantly in the brain at protein level. Present in cortex, cerebellum and midbrain. Found in neurons. Elevated expressions detected in Alzheimer brain samples. Also expressed in testis.1 Publication

Interactioni

Protein-protein interaction databases

BioGridi129958, 2 interactors

Structurei

3D structure databases

SMRiQ8NBC4
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Compositional biasi84 – 87Poly-Pro4

Phylogenomic databases

GeneTreeiENSGT00920000150801
InParanoidiQ8NBC4

Sequencei

Sequence statusi: Complete.

Q8NBC4-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MFPRPVLNSR AQAILLPQPP NMLDHRQWPP RLASFPFTKT GMLSRATSVL
60 70 80 90 100
AGLTAHLWDL GGGAGRRTSK AQRVHPQPSH QRQPPPPQHP GPYQERIWVG
110 120 130 140 150
GEGWGEVGGL RLSKVGRRDR EVGRGLRAPA GRGRAMGGMP RMGTVGDFGQ
160 170 180 190
ALSSLAWTST CFQDFCLPSL PGKLPAPLIS KQQFLSNSSR SLFN
Length:194
Mass (Da):21,159
Last modified:June 15, 2010 - v2
Checksum:i4C0D18500B820F22
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence conflicti123G → R in ADF32072 (PubMed:20376170).Curated1
Sequence conflicti123G → R in ADF32073 (PubMed:20376170).Curated1
Sequence conflicti123G → R in BAC03569 (PubMed:14702039).Curated1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
GU931819 mRNA Translation: ADF32072.1
GU931820 mRNA Translation: ADF32073.1
AK091025 mRNA Translation: BAC03569.1
FO393400 Genomic DNA No translation available.
BC105014 mRNA No translation available.
RefSeqiNP_872390.2, NM_182584.2
UniGeneiHs.353262

Genome annotation databases

EnsembliENST00000360785; ENSP00000495162; ENSG00000198547
ENST00000608990; ENSP00000495424; ENSG00000198547
GeneIDi284805
KEGGihsa:284805

Similar proteinsi

Entry informationi

Entry nameiCT203_HUMAN
AccessioniPrimary (citable) accession number: Q8NBC4
Secondary accession number(s): B8JHY2
Entry historyiIntegrated into UniProtKB/Swiss-Prot: June 15, 2010
Last sequence update: June 15, 2010
Last modified: July 18, 2018
This is version 67 of the entry and version 2 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Human chromosome 20
    Human chromosome 20: entries, gene names and cross-references to MIM

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