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UniProtKB - Q8NA61 (SPERT_HUMAN)

Entry version 132 (18 Sep 2019)
Sequence version 1 (01 Oct 2002)
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Protein

Spermatid-associated protein

Gene

SPERT

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

Complete GO annotation on QuickGO ...

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Spermatid-associated protein
Alternative name(s):
Protein chibby homolog 2
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:SPERT
Synonyms:CBY2
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 13

Organism-specific databases

Human Gene Nomenclature Database

More...HGNCi		HGNC:30720 SPERT

neXtProt; the human protein knowledge platform

More...neXtProti		NX_Q8NA61

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

Open Targets

More...OpenTargetsi		ENSG00000174015

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...PharmGKBi		PA144596272

Miscellaneous databases

Pharos NIH Druggable Genome Knowledgebase

More...Pharosi		Q8NA61

Polymorphism and mutation databases

BioMuta curated single-nucleotide variation and disease association database

More...BioMutai		SPERT

Domain mapping of disease mutations (DMDM)

More...DMDMi		74751135

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00003072911 – 448Spermatid-associated proteinAdd BLAST448

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei41PhosphoserineBy similarity1
Modified residuei86PhosphoserineBy similarity1
Modified residuei89PhosphoserineBy similarity1
Modified residuei97PhosphoserineBy similarity1
Modified residuei124PhosphoserineBy similarity1
Modified residuei144PhosphoserineBy similarity1
Modified residuei148PhosphoserineBy similarity1
Modified residuei150PhosphoserineBy similarity1
Modified residuei212PhosphoserineBy similarity1
Modified residuei225PhosphoserineBy similarity1
Modified residuei335PhosphoserineBy similarity1
Modified residuei338PhosphoserineBy similarity1

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - PTMi

Phosphoprotein

Proteomic databases

jPOST - Japan Proteome Standard Repository/Database

More...jPOSTi		Q8NA61

MassIVE - Mass Spectrometry Interactive Virtual Environment

More...MassIVEi		Q8NA61

PaxDb, a database of protein abundance averages across all three domains of life

More...PaxDbi		Q8NA61

PeptideAtlas

More...PeptideAtlasi		Q8NA61

PRoteomics IDEntifications database

More...PRIDEi		Q8NA61

ProteomicsDB: a multi-organism proteome resource

More...ProteomicsDBi		72645 [Q8NA61-1]
72646 [Q8NA61-2]

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...iPTMneti		Q8NA61

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...PhosphoSitePlusi		Q8NA61

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...Bgeei		ENSG00000174015 Expressed in 26 organ(s), highest expression level in left testis

ExpressionAtlas, Differential and Baseline Expression

More...ExpressionAtlasi		Q8NA61 baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...Genevisiblei		Q8NA61 HS

Organism-specific databases

Human Protein Atlas

More...HPAi		HPA039359
HPA040046

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction_section">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function_section">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

Homodimer. Binds to NEK1 (By similarity).

By similarity

<p>This subsection of the '<a href="http://www.uniprot.org/help/interaction_section%27">Interaction</a> section provides information about binary protein-protein interactions. The data presented in this section are a quality-filtered subset of binary interactions automatically derived from the <a href="http://www.ebi.ac.uk/intact/">IntAct database</a>. It is updated on a monthly basis. Each binary interaction is displayed on a separate line.<p><a href='/help/binary_interactions' target='_top'>More...</a></p>Binary interactionsi

WithEntry#Exp.IntActNotes
B2R6J33EBI-741724,EBI-10175524
ACTN1P128143EBI-741724,EBI-351710
ARHGEF40Q8TER5-23EBI-741724,EBI-10275150
ARMC7Q9H6L43EBI-741724,EBI-742909
C19orf44Q9H6X53EBI-741724,EBI-7112211
C1orf109Q9NX043EBI-741724,EBI-8643161
CCDC146Q8IYE0-23EBI-741724,EBI-10247802
CCDC198Q9NVL83EBI-741724,EBI-10238351
CCHCR1Q8TD31-34EBI-11524851,EBI-10175300
CCNG1P519593EBI-741724,EBI-3905829
CDC23Q9UJX23EBI-741724,EBI-396137
CEP44Q9C0F14EBI-741724,EBI-744115
CEP57L1Q8IYX8-23EBI-741724,EBI-10181988
CEP95Q96GE43EBI-741724,EBI-372775
CHCHD3Q9NX633EBI-741724,EBI-743375
CHIC2Q9UKJ53EBI-741724,EBI-741528
CKS1BP610243EBI-741724,EBI-456371
CNNM3Q8NE013EBI-741724,EBI-741032
CTNNAL1Q9UBT73EBI-741724,EBI-514206
DUSP14O951473EBI-741724,EBI-3922653
DZIP1LQ8IYY44EBI-11524851,EBI-10264440
EIF4E2O605733EBI-741724,EBI-398610
ELOAQ142413EBI-741724,EBI-742350
ENKD1Q9H0I23EBI-741724,EBI-744099
FAM161AQ3B8204EBI-11524851,EBI-719941
FRS3O435593EBI-741724,EBI-725515
GOLGA6L2Q8N9W4-23EBI-741724,EBI-10268729
HAUS1Q96CS23EBI-741724,EBI-2514791
ING5Q8WYH84EBI-11524851,EBI-488533
KIFC3Q9BVG85EBI-741724,EBI-2125614
KIFC3Q9BVG8-54EBI-11524851,EBI-14069005
KLC3Q6P5973EBI-741724,EBI-1643885
LATS1Q6PJG33EBI-741724,EBI-10253976
LENG1Q96BZ83EBI-741724,EBI-726510
LMO1P258003EBI-741724,EBI-8639312
LMO2P257913EBI-741724,EBI-739696
LMO3Q8TAP43EBI-741724,EBI-742259
LNX1Q8TBB16EBI-11524851,EBI-739832
MED28Q9H2043EBI-741724,EBI-514199
METTL17Q9H7H03EBI-741724,EBI-749353
METTL17Q9H7H0-23EBI-11524851,EBI-11098807
MLH1P406929EBI-11524851,EBI-744248
MMABQ96EY83EBI-11524851,EBI-7825413
MOSP005403EBI-741724,EBI-1757866
PID1Q7Z2X43EBI-741724,EBI-10256685
PIN1Q135263EBI-741724,EBI-714158
PLEKHN1Q494U13EBI-741724,EBI-10241513
POLR1CO151604EBI-11524851,EBI-1055079
PPP1R18Q6NYC83EBI-741724,EBI-2557469
RNF6A0A0S2Z4G93EBI-11524851,EBI-16428950
RPL9P9P329693EBI-741724,EBI-358122
RTP5Q14D333EBI-741724,EBI-10217913
RUNX1T1Q06455-43EBI-741724,EBI-10224192
SCNM1Q9BWG64EBI-11524851,EBI-748391
SH3RF2Q08AM83EBI-741724,EBI-10225873
SYCE1Q8N0S24EBI-11524851,EBI-6872807
TCEANCQ8N8B73EBI-741724,EBI-954696
TEX11Q8IYF33EBI-741724,EBI-742397
TRIM42Q8IWZ53EBI-741724,EBI-5235829
TSGA10Q9BZW73EBI-741724,EBI-744794
TXLNAP402223EBI-741724,EBI-359793
TXLNBQ8N3L33EBI-741724,EBI-6116822
WDYHV1Q96HA84EBI-11524851,EBI-741158
ZC2HC1CQ53FD03EBI-741724,EBI-740767
ZMAT2Q96NC03EBI-741724,EBI-2682299
ZNF564Q8TBZ83EBI-741724,EBI-10273713
ZNF581Q9P0T43EBI-741724,EBI-745520
ZNF655Q8N7203EBI-741724,EBI-625509
ZNF688A0A0S2Z5X43EBI-11524851,EBI-16429014

GO - Molecular functioni

Complete GO annotation on QuickGO ...

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGrid)

More...BioGridi		128627, 97 interactors

Protein interaction database and analysis system

More...IntActi		Q8NA61, 130 interactors

Molecular INTeraction database

More...MINTi		Q8NA61

STRING: functional protein association networks

More...STRINGi		9606.ENSP00000309189

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...SMRi		Q8NA61

Database of comparative protein structure models

More...ModBasei		Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and domains’ section denotes the positions of regions of coiled coil within the protein.<p><a href='/help/coiled' target='_top'>More...</a></p>Coiled coili164 – 198Sequence analysisAdd BLAST35
Coiled coili242 – 267Sequence analysisAdd BLAST26
Coiled coili356 – 414Sequence analysisAdd BLAST59

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the chibby family. SPERT subfamily.Curated

Keywords - Domaini

Coiled coil

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...eggNOGi		ENOG410IVSP Eukaryota
ENOG41116VI LUCA

Ensembl GeneTree

More...GeneTreei		ENSGT00940000153137

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...HOGENOMi		HOG000154381

InParanoid: Eukaryotic Ortholog Groups

More...InParanoidi		Q8NA61

KEGG Orthology (KO)

More...KOi		K23403

Identification of Orthologs from Complete Genome Data

More...OMAi		LHNLYPT

Database of Orthologous Groups

More...OrthoDBi		1015941at2759

Database for complete collections of gene phylogenies

More...PhylomeDBi		Q8NA61

TreeFam database of animal gene trees

More...TreeFami		TF324419

Family and domain databases

Conserved Domains Database

More...CDDi		cd07429 Cby_like, 1 hit

Integrated resource of protein families, domains and functional sites

More...InterProi		View protein in InterPro
IPR028118 Chibby_fam
IPR026655 SPERT

The PANTHER Classification System

More...PANTHERi		PTHR21533:SF13 PTHR21533:SF13, 1 hit

Pfam protein domain database

More...Pfami		View protein in Pfam
PF14645 Chibby, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequences (2+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry describes 2 <p>This subsection of the ‘Sequence’ section lists the alternative protein sequences (isoforms) that can be generated from the same gene by a single or by the combination of up to four biological events (alternative promoter usage, alternative splicing, alternative initiation and ribosomal frameshifting). Additionally, this section gives relevant information on each alternative protein isoform.<p><a href='/help/alternative_products' target='_top'>More...</a></p> isoformsi produced by alternative splicing. AlignAdd to basket

This entry has 2 described isoforms and 1 potential isoform that is computationally mapped.Show allAlign All

Isoform 1 (identifier: Q8NA61-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the <div> <p><b>What is the canonical sequence?</b><p><a href='/help/canonical_and_isoforms' target='_top'>More...</a></p>canonicali sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide
        10         20         30         40         50
MSPLECSECF GDQLLHRTYT WQLTLHSRPN YTRKRDTRSE SLEIPISVVL 
        60         70         80         90        100
PQRGTAEPFP RLHNLYSTPR CAQQAALPRL SRRMASQHSY PLNRFSSVPL 
       110        120        130        140        150
DPMERPMSQA DLELDYNPPR VQLSDEMFVF QDGRWVNENC RLQSPYFSPS 
       160        170        180        190        200
ASFHHKLHHK RLAKECMLQE ENKSLREENK ALREENRMLS KENKILQVFW 
       210        220        230        240        250
EEHKASLGRE ESRAPSPLLH KDSASLEVVK KDHVALQVPR GKEDSTLQLL 
       260        270        280        290        300
REENRALQQL LEQKQAYWAQ AEDTAAPAEE SKPAPSPHEE PCSPGLLQDQ 
       310        320        330        340        350
GSGLSSRFEE PKGPPARQED SKELRALRKM VSNMSGPSGE EEAKVGPGLP 
       360        370        380        390        400
DGCQPLQLLR EMRQALQALL KENRLLQEEN RTLQVLRAEH RGFQEENKAL 
       410        420        430        440 
WENNKLKLQQ KLVIDTVTEV TARMEMLIEE LYAFMPARSQ DPKKPSRV
Length:448
Mass (Da):51,570
Last modified:October 1, 2002 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iD59271CFE59F8863
GO
Isoform 2 (identifier: Q8NA61-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     1-36: Missing.
     37-52: TRSESLEIPISVVLPQ → MQPEGLKCRMEESNAE

Show »
Length:412
Mass (Da):47,289
Checksum:i6EC3B47EF08CDE10
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There is 1 potential isoform mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
E9PLB4E9PLB4_HUMAN
Spermatid-associated protein
SPERT
160Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section describes natural variant(s) of the protein sequence.<p><a href='/help/variant' target='_top'>More...</a></p>Natural variantiVAR_054064329K → E. Corresponds to variant dbSNP:rs7317245Ensembl.1

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section describes the sequence of naturally occurring alternative protein isoform(s). The changes in the amino acid sequence may be due to alternative splicing, alternative promoter usage, alternative initiation, or ribosomal frameshifting.<p><a href='/help/var_seq' target='_top'>More...</a></p>Alternative sequenceiVSP_0286731 – 36Missing in isoform 2. 2 PublicationsAdd BLAST36
Alternative sequenceiVSP_02867437 – 52TRSES…VVLPQ → MQPEGLKCRMEESNAE in isoform 2. 2 PublicationsAdd BLAST16

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...EMBLi

GenBank nucleotide sequence database

More...GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...DDBJi
Links Updated
AK093129 mRNA Translation: BAC04067.1
AK292350 mRNA Translation: BAF85039.1
AL139320 Genomic DNA No translation available.
BC027609 mRNA Translation: AAH27609.1

The Consensus CDS (CCDS) project

More...CCDSi		CCDS66540.1 [Q8NA61-2]
CCDS9399.1 [Q8NA61-1]

NCBI Reference Sequences

More...RefSeqi		NP_001273270.1, NM_001286341.1
NP_001273271.1, NM_001286342.1 [Q8NA61-2]
NP_689932.1, NM_152719.2 [Q8NA61-1]

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...Ensembli		ENST00000310521; ENSP00000309189; ENSG00000174015 [Q8NA61-1]
ENST00000378966; ENSP00000368249; ENSG00000174015 [Q8NA61-2]
ENST00000610924; ENSP00000480148; ENSG00000174015 [Q8NA61-2]

Database of genes from NCBI RefSeq genomes

More...GeneIDi		220082

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...KEGGi		hsa:220082

UCSC genome browser

More...UCSCi		uc001van.3 human [Q8NA61-1]

Keywords - Coding sequence diversityi

Alternative splicing, Polymorphism

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK093129 mRNA Translation: BAC04067.1
AK292350 mRNA Translation: BAF85039.1
AL139320 Genomic DNA No translation available.
BC027609 mRNA Translation: AAH27609.1
CCDSiCCDS66540.1 [Q8NA61-2]
CCDS9399.1 [Q8NA61-1]
RefSeqiNP_001273270.1, NM_001286341.1
NP_001273271.1, NM_001286342.1 [Q8NA61-2]
NP_689932.1, NM_152719.2 [Q8NA61-1]

3D structure databases

SMRiQ8NA61
ModBaseiSearch...

Protein-protein interaction databases

BioGridi128627, 97 interactors
IntActiQ8NA61, 130 interactors
MINTiQ8NA61
STRINGi9606.ENSP00000309189

PTM databases

iPTMnetiQ8NA61
PhosphoSitePlusiQ8NA61

Polymorphism and mutation databases

BioMutaiSPERT
DMDMi74751135

Proteomic databases

jPOSTiQ8NA61
MassIVEiQ8NA61
PaxDbiQ8NA61
PeptideAtlasiQ8NA61
PRIDEiQ8NA61
ProteomicsDBi72645 [Q8NA61-1]
72646 [Q8NA61-2]

Genome annotation databases

EnsembliENST00000310521; ENSP00000309189; ENSG00000174015 [Q8NA61-1]
ENST00000378966; ENSP00000368249; ENSG00000174015 [Q8NA61-2]
ENST00000610924; ENSP00000480148; ENSG00000174015 [Q8NA61-2]
GeneIDi220082
KEGGihsa:220082
UCSCiuc001van.3 human [Q8NA61-1]

Organism-specific databases

Comparative Toxicogenomics Database

More...CTDi		220082

GeneCards: human genes, protein and diseases

More...GeneCardsi		SPERT
HGNCiHGNC:30720 SPERT
HPAiHPA039359
HPA040046
neXtProtiNX_Q8NA61
OpenTargetsiENSG00000174015
PharmGKBiPA144596272

GenAtlas: human gene database

More...GenAtlasi		Search...

Phylogenomic databases

eggNOGiENOG410IVSP Eukaryota
ENOG41116VI LUCA
GeneTreeiENSGT00940000153137
HOGENOMiHOG000154381
InParanoidiQ8NA61
KOiK23403
OMAiLHNLYPT
OrthoDBi1015941at2759
PhylomeDBiQ8NA61
TreeFamiTF324419

Miscellaneous databases

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...GenomeRNAii		220082
PharosiQ8NA61

Protein Ontology

More...PROi		PR:Q8NA61

Gene expression databases

BgeeiENSG00000174015 Expressed in 26 organ(s), highest expression level in left testis
ExpressionAtlasiQ8NA61 baseline and differential
GenevisibleiQ8NA61 HS

Family and domain databases

CDDicd07429 Cby_like, 1 hit
InterProiView protein in InterPro
IPR028118 Chibby_fam
IPR026655 SPERT
PANTHERiPTHR21533:SF13 PTHR21533:SF13, 1 hit
PfamiView protein in Pfam
PF14645 Chibby, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...ProtoNeti		Search...

MobiDB: a database of protein disorder and mobility annotations

More...MobiDBi		Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiSPERT_HUMAN
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q8NA61
Secondary accession number(s): A8K8I5, Q8NHV2
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: October 23, 2007
Last sequence update: October 1, 2002
Last modified: September 18, 2019
This is version 132 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. Human polymorphisms and disease mutations
    Index of human polymorphisms and disease mutations
  3. Human chromosome 13
    Human chromosome 13: entries, gene names and cross-references to MIM
  4. Human entries with polymorphisms or disease mutations
    List of human entries with polymorphisms or disease mutations
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