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UniProtKB - Q8N9Z9 (LMTD1_HUMAN)

Entry version 121 (07 Apr 2021)
Sequence version 2 (18 May 2010)
Previous versions | rss
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Protein

Lamin tail domain-containing protein 1

Gene

LMNTD1

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:3 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>-Experimental evidence at transcript leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Biological processi

Complete GO annotation on QuickGO ...

Enzyme and pathway databases

Pathway Commons web resource for biological pathway data

More...PathwayCommonsi		Q8N9Z9

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Lamin tail domain-containing protein 1
Alternative name(s):
Intermediate filament tail domain-containing protein 1
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:LMNTD1
Synonyms:IFLTD1
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 12

Organism-specific databases

Human Gene Nomenclature Database

More...HGNCi		HGNC:26683, LMNTD1

neXtProt; the human protein knowledge platform

More...neXtProti		NX_Q8N9Z9

Eukaryotic Pathogen, Vector and Host Database Resources

More...VEuPathDBi		HostDB:ENSG00000152936.10

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Cellular componenti

Intermediate filament

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

DisGeNET

More...DisGeNETi		160492

Open Targets

More...OpenTargetsi		ENSG00000152936

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...PharmGKBi		PA162391895

Miscellaneous databases

Pharos NIH Druggable Genome Knowledgebase

More...Pharosi		Q8N9Z9, Tdark

Genetic variation databases

BioMuta curated single-nucleotide variation and disease association database

More...BioMutai		LMNTD1

Domain mapping of disease mutations (DMDM)

More...DMDMi		296434538

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00003172471 – 388Lamin tail domain-containing protein 1Add BLAST388

Proteomic databases

PaxDb, a database of protein abundance averages across all three domains of life

More...PaxDbi		Q8N9Z9

PeptideAtlas

More...PeptideAtlasi		Q8N9Z9

PRoteomics IDEntifications database

More...PRIDEi		Q8N9Z9

ProteomicsDB: a multi-organism proteome resource

More...ProteomicsDBi		72615 [Q8N9Z9-1]
72616 [Q8N9Z9-2]
72617 [Q8N9Z9-3]
72618 [Q8N9Z9-4]
72619 [Q8N9Z9-5]

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...iPTMneti		Q8N9Z9

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...PhosphoSitePlusi		Q8N9Z9

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...Bgeei		ENSG00000152936, Expressed in right uterine tube and 83 other tissues

ExpressionAtlas, Differential and Baseline Expression

More...ExpressionAtlasi		Q8N9Z9, baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...Genevisiblei		Q8N9Z9, HS

Organism-specific databases

Human Protein Atlas

More...HPAi		ENSG00000152936, Tissue enhanced (brain, fallopian tube, pituitary gland, testis)

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGRID)

More...BioGRIDi		127760, 3 interactors

Protein interaction database and analysis system

More...IntActi		Q8N9Z9, 1 interactor

STRING: functional protein association networks

More...STRINGi		9606.ENSP00000407353

Miscellaneous databases

RNAct, Protein-RNA interaction predictions for model organisms.

More...RNActi		Q8N9Z9, protein

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...SMRi		Q8N9Z9

Database of comparative protein structure models

More...ModBasei		Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini136 – 254LTDPROSITE-ProRule annotationAdd BLAST119

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the intermediate filament family.Curated

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...eggNOGi		KOG0977, Eukaryota

Ensembl GeneTree

More...GeneTreei		ENSGT00910000144343

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...HOGENOMi		CLU_048894_1_0_1

InParanoid: Eukaryotic Ortholog Groups

More...InParanoidi		Q8N9Z9

Identification of Orthologs from Complete Genome Data

More...OMAi		GMPLGYY

Database of Orthologous Groups

More...OrthoDBi		716378at2759

Database for complete collections of gene phylogenies

More...PhylomeDBi		Q8N9Z9

TreeFam database of animal gene trees

More...TreeFami		TF338357

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...Gene3Di		2.60.40.1260, 1 hit

Integrated resource of protein families, domains and functional sites

More...InterProi		View protein in InterPro
IPR001322, Lamin_tail_dom
IPR036415, Lamin_tail_dom_sf
IPR042840, LMNTD1

The PANTHER Classification System

More...PANTHERi		PTHR47012, PTHR47012, 1 hit

Pfam protein domain database

More...Pfami		View protein in Pfam
PF00932, LTD, 1 hit

Superfamily database of structural and functional annotation

More...SUPFAMi		SSF74853, SSF74853, 1 hit

PROSITE; a protein domain and family database

More...PROSITEi		View protein in PROSITE
PS51841, LTD, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequences (5+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry describes 5 <p>This subsection of the 'Sequence' section lists the alternative protein sequences (isoforms) that can be generated from the same gene by a single or by the combination of up to four biological events (alternative promoter usage, alternative splicing, alternative initiation and ribosomal frameshifting). Additionally, this section gives relevant information on each alternative protein isoform. This section is only present in reviewed entries, i.e. in UniProtKB/Swiss-Prot.<p><a href='/help/alternative_products' target='_top'>More...</a></p> isoformsi produced by alternative splicing. AlignAdd to basket

This entry has 5 described isoforms and 6 potential isoforms that are computationally mapped.Show allAlign All

Isoform 1 (identifier: Q8N9Z9-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the <div> <p><b>What is the canonical sequence?</b><p><a href='/help/canonical_and_isoforms' target='_top'>More...</a></p>canonicali sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide
        10         20         30         40         50
MLEGSWINRR EDKLGVYSLV HFSPKMLGSV ATTLPLSSSN SSGMPLGYYL 
        60         70         80         90        100
SSPQISRVTI STTGQLTSKA TVGSCSRVEN SLDASPFSVP KKQDESPMIG 
       110        120        130        140        150
DGEDYFLSLF GDSKKLTAHS NYTQKTLKYF SMILEEVGQF TSSSLGDVEI 
       160        170        180        190        200
AEVNVKGLFV KLINSSLDKE MAIGDHILQQ NVNGQTISLY RFLPNIVMQA 
       210        220        230        240        250
NSTVTVWAAA SEAKHQPPSD FLWKEQDKFR ASPDCITILC KPNGQAIAWY 
       260        270        280        290        300
TPIHWKQAWE KLDADVEFNR CSVVSPTFRK RVFQWTASTA TITKEKQDQP 
       310        320        330        340        350
KKDISNYQVE QAQVLLKREK EIPPTVFPNR SPWCQNPYVS AHPYCPLIEP 
       360        370        380 
HNTSTAGGRL DRQPRTRSTR PNRASGSKKK KTSESQKQ
Length:388
Mass (Da):43,408
Last modified:May 18, 2010 - v2
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iF5934FA7DA8E2170
GO
Isoform 2 (identifier: Q8N9Z9-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     1-97: Missing.

Show »
Length:291
Mass (Da):33,043
Checksum:iF62420E9E63B546B
GO
Isoform 3 (identifier: Q8N9Z9-3) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     1-63: Missing.
     64-83: GQLTSKATVGSCSRVENSLD → MQQPVRAGDIGVSRVQTHHN

Show »
Length:325
Mass (Da):36,755
Checksum:i72277BF2C649AE62
GO
Isoform 4 (identifier: Q8N9Z9-4) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     1-9: MLEGSWINR → MKDTQDIQEASKAMQNKVHEQEDKNEKQKQ
     206-245: Missing.

Show »
Length:369
Mass (Da):41,395
Checksum:iDA61CC73D814A55B
GO
Isoform 5 (identifier: Q8N9Z9-5) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     1-9: MLEGSWINR → MKDTQDIQEASKAMQNKVHEQEDKNEKQKQ

Show »
Length:409
Mass (Da):45,891
Checksum:i39B923E5391AC919
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 6 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
F5H8G2F5H8G2_HUMAN
Lamin tail domain-containing protei...
LMNTD1
143Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
H0YFE3H0YFE3_HUMAN
Lamin tail domain-containing protei...
LMNTD1
105Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
H0YFH5H0YFH5_HUMAN
Lamin tail domain-containing protei...
LMNTD1
163Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
F5H3Q3F5H3Q3_HUMAN
Lamin tail domain-containing protei...
LMNTD1
165Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
F5H719F5H719_HUMAN
Lamin tail domain-containing protei...
LMNTD1
170Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
F5H5I3F5H5I3_HUMAN
Lamin tail domain-containing protei...
LMNTD1
72Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti10R → K in BAC04132 (PubMed:14702039).Curated1
Sequence conflicti381K → E in BAG59389 (PubMed:14702039).Curated1

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section describes natural variant(s) of the protein sequence.<p><a href='/help/variant' target='_top'>More...</a></p>Natural variantiVAR_049809264A → T. Corresponds to variant dbSNP:rs35450203Ensembl.1
Natural variantiVAR_049810267E → G. Corresponds to variant dbSNP:rs34326830Ensembl.1
Natural variantiVAR_049811289T → A. Corresponds to variant dbSNP:rs34732786Ensembl.1
Natural variantiVAR_049812290A → T. Corresponds to variant dbSNP:rs34074522Ensembl.1
Natural variantiVAR_049813366T → S3 PublicationsCorresponds to variant dbSNP:rs1479500Ensembl.1

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section describes the sequence of naturally occurring alternative protein isoform(s). The changes in the amino acid sequence may be due to alternative splicing, alternative promoter usage, alternative initiation, or ribosomal frameshifting.<p><a href='/help/var_seq' target='_top'>More...</a></p>Alternative sequenceiVSP_0309221 – 97Missing in isoform 2. 1 PublicationAdd BLAST97
Alternative sequenceiVSP_0404891 – 63Missing in isoform 3. 1 PublicationAdd BLAST63
Alternative sequenceiVSP_0404901 – 9MLEGSWINR → MKDTQDIQEASKAMQNKVHE QEDKNEKQKQ in isoform 4 and isoform 5. 1 Publication9
Alternative sequenceiVSP_04049164 – 83GQLTS…ENSLD → MQQPVRAGDIGVSRVQTHHN in isoform 3. 1 PublicationAdd BLAST20
Alternative sequenceiVSP_040492206 – 245Missing in isoform 4. 1 PublicationAdd BLAST40

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...EMBLi

GenBank nucleotide sequence database

More...GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...DDBJi
Links Updated
AK093323 mRNA Translation: BAC04132.1
AK296816 mRNA Translation: BAG59389.1
AK302292 mRNA Translation: BAG63632.1
AK310411 mRNA No translation available.
AC022367 Genomic DNA No translation available.
CH471094 Genomic DNA Translation: EAW96516.1
BC037957 mRNA Translation: AAH37957.1

The Consensus CDS (CCDS) project

More...CCDSi		CCDS44847.1 [Q8N9Z9-3]
CCDS44848.1 [Q8N9Z9-4]
CCDS44849.1 [Q8N9Z9-5]
CCDS58218.1 [Q8N9Z9-2]
CCDS8704.1 [Q8N9Z9-1]

NCBI Reference Sequences

More...RefSeqi		NP_001139199.1, NM_001145727.2 [Q8N9Z9-3]
NP_001139200.1, NM_001145728.2 [Q8N9Z9-5]
NP_001139201.1, NM_001145729.1 [Q8N9Z9-4]
NP_001243195.1, NM_001256266.1 [Q8N9Z9-2]
NP_689803.2, NM_152590.3 [Q8N9Z9-1]
XP_011518877.1, XM_011520575.1 [Q8N9Z9-5]
XP_011518878.1, XM_011520576.2 [Q8N9Z9-5]
XP_011518879.1, XM_011520577.2 [Q8N9Z9-5]
XP_011518880.1, XM_011520578.2 [Q8N9Z9-5]
XP_011518882.1, XM_011520580.1 [Q8N9Z9-4]
XP_016874380.1, XM_017018891.1 [Q8N9Z9-5]

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...Ensembli		ENST00000282881; ENSP00000282881; ENSG00000152936 [Q8N9Z9-1]
ENST00000413632; ENSP00000393150; ENSG00000152936 [Q8N9Z9-4]
ENST00000445693; ENSP00000407043; ENSG00000152936 [Q8N9Z9-3]
ENST00000458174; ENSP00000407353; ENSG00000152936 [Q8N9Z9-5]
ENST00000539744; ENSP00000443132; ENSG00000152936 [Q8N9Z9-2]

Database of genes from NCBI RefSeq genomes

More...GeneIDi		160492

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...KEGGi		hsa:160492

UCSC genome browser

More...UCSCi		uc001rgs.3, human [Q8N9Z9-1]

Keywords - Coding sequence diversityi

Alternative splicing

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK093323 mRNA Translation: BAC04132.1
AK296816 mRNA Translation: BAG59389.1
AK302292 mRNA Translation: BAG63632.1
AK310411 mRNA No translation available.
AC022367 Genomic DNA No translation available.
CH471094 Genomic DNA Translation: EAW96516.1
BC037957 mRNA Translation: AAH37957.1
CCDSiCCDS44847.1 [Q8N9Z9-3]
CCDS44848.1 [Q8N9Z9-4]
CCDS44849.1 [Q8N9Z9-5]
CCDS58218.1 [Q8N9Z9-2]
CCDS8704.1 [Q8N9Z9-1]
RefSeqiNP_001139199.1, NM_001145727.2 [Q8N9Z9-3]
NP_001139200.1, NM_001145728.2 [Q8N9Z9-5]
NP_001139201.1, NM_001145729.1 [Q8N9Z9-4]
NP_001243195.1, NM_001256266.1 [Q8N9Z9-2]
NP_689803.2, NM_152590.3 [Q8N9Z9-1]
XP_011518877.1, XM_011520575.1 [Q8N9Z9-5]
XP_011518878.1, XM_011520576.2 [Q8N9Z9-5]
XP_011518879.1, XM_011520577.2 [Q8N9Z9-5]
XP_011518880.1, XM_011520578.2 [Q8N9Z9-5]
XP_011518882.1, XM_011520580.1 [Q8N9Z9-4]
XP_016874380.1, XM_017018891.1 [Q8N9Z9-5]

3D structure databases

SMRiQ8N9Z9
ModBaseiSearch...

Protein-protein interaction databases

BioGRIDi127760, 3 interactors
IntActiQ8N9Z9, 1 interactor
STRINGi9606.ENSP00000407353

PTM databases

iPTMnetiQ8N9Z9
PhosphoSitePlusiQ8N9Z9

Genetic variation databases

BioMutaiLMNTD1
DMDMi296434538

Proteomic databases

PaxDbiQ8N9Z9
PeptideAtlasiQ8N9Z9
PRIDEiQ8N9Z9
ProteomicsDBi72615 [Q8N9Z9-1]
72616 [Q8N9Z9-2]
72617 [Q8N9Z9-3]
72618 [Q8N9Z9-4]
72619 [Q8N9Z9-5]

Protocols and materials databases

Antibodypedia a portal for validated antibodies

More...Antibodypediai		42350, 110 antibodies

Genome annotation databases

EnsembliENST00000282881; ENSP00000282881; ENSG00000152936 [Q8N9Z9-1]
ENST00000413632; ENSP00000393150; ENSG00000152936 [Q8N9Z9-4]
ENST00000445693; ENSP00000407043; ENSG00000152936 [Q8N9Z9-3]
ENST00000458174; ENSP00000407353; ENSG00000152936 [Q8N9Z9-5]
ENST00000539744; ENSP00000443132; ENSG00000152936 [Q8N9Z9-2]
GeneIDi160492
KEGGihsa:160492
UCSCiuc001rgs.3, human [Q8N9Z9-1]

Organism-specific databases

Comparative Toxicogenomics Database

More...CTDi		160492
DisGeNETi160492

GeneCards: human genes, protein and diseases

More...GeneCardsi		LMNTD1
HGNCiHGNC:26683, LMNTD1
HPAiENSG00000152936, Tissue enhanced (brain, fallopian tube, pituitary gland, testis)
neXtProtiNX_Q8N9Z9
OpenTargetsiENSG00000152936
PharmGKBiPA162391895
VEuPathDBiHostDB:ENSG00000152936.10

GenAtlas: human gene database

More...GenAtlasi		Search...

Phylogenomic databases

eggNOGiKOG0977, Eukaryota
GeneTreeiENSGT00910000144343
HOGENOMiCLU_048894_1_0_1
InParanoidiQ8N9Z9
OMAiGMPLGYY
OrthoDBi716378at2759
PhylomeDBiQ8N9Z9
TreeFamiTF338357

Enzyme and pathway databases

PathwayCommonsiQ8N9Z9

Miscellaneous databases

BioGRID ORCS database of CRISPR phenotype screens

More...BioGRID-ORCSi		160492, 5 hits in 977 CRISPR screens

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...ChiTaRSi		LMNTD1, human

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...GenomeRNAii		160492
PharosiQ8N9Z9, Tdark

Protein Ontology

More...PROi		PR:Q8N9Z9
RNActiQ8N9Z9, protein

Gene expression databases

BgeeiENSG00000152936, Expressed in right uterine tube and 83 other tissues
ExpressionAtlasiQ8N9Z9, baseline and differential
GenevisibleiQ8N9Z9, HS

Family and domain databases

Gene3Di2.60.40.1260, 1 hit
InterProiView protein in InterPro
IPR001322, Lamin_tail_dom
IPR036415, Lamin_tail_dom_sf
IPR042840, LMNTD1
PANTHERiPTHR47012, PTHR47012, 1 hit
PfamiView protein in Pfam
PF00932, LTD, 1 hit
SUPFAMiSSF74853, SSF74853, 1 hit
PROSITEiView protein in PROSITE
PS51841, LTD, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...ProtoNeti		Search...

MobiDB: a database of protein disorder and mobility annotations

More...MobiDBi		Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiLMTD1_HUMAN
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q8N9Z9
Secondary accession number(s): B4DL27, B4DY70, Q8IY38
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: February 5, 2008
Last sequence update: May 18, 2010
Last modified: April 7, 2021
This is version 121 of the entry and version 2 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. Human chromosome 12
    Human chromosome 12: entries, gene names and cross-references to MIM
  2. Human entries with genetic variants
    List of human entries with genetic variants
  3. Human variants curated from literature reports
    Index of human variants curated from literature reports
  4. SIMILARITY comments
    Index of protein domains and families
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