TMEM75

Names & Taxonomyⁱ

Protein namesⁱ	Recommended name: Transmembrane protein 75
Gene namesⁱ	Name:TMEM75
Organismⁱ	Homo sapiens (Human)
Taxonomic identifierⁱ	9606 [NCBI]
Taxonomic lineageⁱ	cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Dipnotetrapodomorpha › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Boreoeutheria › Euarchontoglires › Primates › Haplorrhini › Simiiformes › Catarrhini › Hominoidea › Hominidae › Homininae › Homo
Proteomesⁱ	UP000005640 Componentⁱ: Unplaced

Organism-specific databases

Human Gene Nomenclature Database More...HGNCⁱ	HGNC:32295 TMEM75
neXtProtⁱ	NX_Q8N9X5

Topology

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Transmembraneⁱ	32 – 52	HelicalSequence analysisAdd BLAST		21
Transmembraneⁱ	65 – 85	HelicalSequence analysisAdd BLAST		21

Keywords - Cellular componentⁱ

Membrane

Pathology & Biotechⁱ

Polymorphism and mutation databases

DMDMⁱ	74729788

DMDMⁱ

74729788

PTM / Processingⁱ

Molecule processing

Feature key	Position(s)	DescriptionActions	Graphical view	Length
ChainⁱPRO_0000271080	1 – 138	Transmembrane protein 75Add BLAST		138

Proteomic databases

PaxDbⁱ	Q8N9X5
PeptideAtlas More...PeptideAtlasⁱ	Q8N9X5
PRIDEⁱ	Q8N9X5
ProteomicsDBⁱ	72607

Expressionⁱ

Gene expression databases

CleanExⁱ	HS_TMEM75

CleanExⁱ

HS_TMEM75

Interactionⁱ

Protein-protein interaction databases

STRINGⁱ	9606.ENSP00000446264

STRINGⁱ

9606.ENSP00000446264

Structureⁱ

3D structure databases

ProteinModelPortalⁱ	Q8N9X5
ModBaseⁱ	Search...
MobiDBⁱ	Search...

Family & Domainsⁱ

Keywords - Domainⁱ

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGⁱ	ENOG410KCGF Eukaryota ENOG4110NZT LUCA
InParanoidⁱ	Q8N9X5
PhylomeDBⁱ	Q8N9X5

Sequenceⁱ

Sequence statusⁱ: Complete.

Q8N9X5-1 [UniParc]FASTA Add to basket

« Hide

        10         20         30         40         50
MRPTADSFRL KKGNVFPNFD PCAQALQKSC HFALSFLIGK MGIIILSVCL 
        60         70         80         90        100
ICTRLLQEGI AQSKCLINVS FSLYSCFIVF VTISQDSETL SLDCDHRLFF 
       110        120        130 
SLPFTDPASG GQSQHSWPCP ERSKNLPQVS KQLRNRAG

Length:138

Mass (Da):15,361

Last modified:October 1, 2002 - v1

Checksum:ⁱ113B3E911FC9ED79

GO

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	AK093424 mRNA No translation available. AC103705 Genomic DNA No translation available. BC137383 mRNA Translation: AAI37384.1 BC137385 mRNA Translation: AAI37386.1
UniGeneⁱ	Hs.629674

Similar proteinsⁱ

50% Identity

Protein	Similar proteins		Species	Score	Length	Source
Q8N9X5	Uncharacterized protein (Fragment)		MACFA		138	UniRef50_Q8N9X5
Uncharacterized protein		CHLSB		138
Uncharacterized protein (Fragment)		MACMU		138
Uncharacterized protein		PONAB		138

Entry informationⁱ

Entry nameⁱ	TMM75_HUMAN
Accessionⁱ	Q8N9X5Primary (citable) accession number: Q8N9X5 Secondary accession number(s): B2RPD6, B9EH93
Entry historyⁱ	Integrated into UniProtKB/Swiss-Prot:	January 9, 2007
	Last sequence update:	October 1, 2002
	Last modified:	June 20, 2018
	This is version 70 of the entry and version 1 of the sequence. See complete history.
Entry statusⁱ	Reviewed (UniProtKB/Swiss-Prot)
Annotation program	Chordata Protein Annotation Program
Disclaimer	Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousⁱ

Keywords - Technical termⁱ

Complete proteome, Reference proteome

UniProtKB - Q8N9X5 (TMM75_HUMAN)

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Transmembrane protein 75

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Names & Taxonomyⁱ

Organism-specific databases

Subcellular locationⁱ

Other locations

Other locations

Topology

Keywords - Cellular componentⁱ

Pathology & Biotechⁱ

Polymorphism and mutation databases

PTM / Processingⁱ

Molecule processing

Proteomic databases

Expressionⁱ

Gene expression databases

Interactionⁱ

Protein-protein interaction databases

Structureⁱ

3D structure databases

Family & Domainsⁱ

Keywords - Domainⁱ

Phylogenomic databases

Sequenceⁱ

Sequence databases

Similar proteinsⁱ

Entry informationⁱ

Miscellaneousⁱ

Keywords - Technical termⁱ

UniProt is an ELIXIR core data resource

UniProtKB

UniParc

Help

UniRef

Proteomes

Annotation systems

Supporting data

UniProtKB - Q8N9X5 (TMM75_HUMAN)

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Transmembrane protein 75

TMEM75

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<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

Organism-specific databases

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Other locations

Other locations

Topology

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Polymorphism and mutation databases

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Proteomic databases

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Keywords - Domaini

Phylogenomic databases

Sequence databases

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

UniProt is an ELIXIR core data resource

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Names & Taxonomyⁱ

Subcellular locationⁱ

Pathology & Biotechⁱ

PTM / Processingⁱ

Expressionⁱ

Interactionⁱ

Structureⁱ

Family & Domainsⁱ

Keywords - Domainⁱ

Entry informationⁱ

Miscellaneousⁱ

Keywords - Technical termⁱ