CDRT4

Names & Taxonomyⁱ

Protein namesⁱ	Recommended name: CMT1A duplicated region transcript 4 protein
Gene namesⁱ	Name:CDRT4
Organismⁱ	Homo sapiens (Human)
Taxonomic identifierⁱ	9606 [NCBI]
Taxonomic lineageⁱ	cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Dipnotetrapodomorpha › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Boreoeutheria › Euarchontoglires › Primates › Haplorrhini › Simiiformes › Catarrhini › Hominoidea › Hominidae › Homininae › Homo
Proteomesⁱ	UP000005640 Componentⁱ: Unplaced

Organism-specific databases

Human Gene Nomenclature Database More...HGNCⁱ	HGNC:14383 CDRT4
neXtProtⁱ	NX_Q8N9R6

Pathology & Biotechⁱ

Organism-specific databases

PharmGKBⁱ	PA26340

PharmGKBⁱ

PA26340

Polymorphism and mutation databases

BioMutaⁱ	CDRT4
DMDMⁱ	296434438

PTM / Processingⁱ

Molecule processing

Feature key	Position(s)	DescriptionActions	Graphical view	Length
ChainⁱPRO_0000314903	1 – 151	CMT1A duplicated region transcript 4 proteinAdd BLAST		151

Proteomic databases

PaxDbⁱ	Q8N9R6
PeptideAtlas More...PeptideAtlasⁱ	Q8N9R6
PRIDEⁱ	Q8N9R6
ProteomicsDBⁱ	72575

Expressionⁱ

Tissue specificityⁱ

Expressed in fetal skeletal muscle and kidney.1 Publication

Gene expression databases

CleanExⁱ	HS_CDRT4

CleanExⁱ

HS_CDRT4

Organism-specific databases

Human Protein Atlas More...HPAⁱ	HPA021590

HPAⁱ

HPA021590

Interactionⁱ

Protein-protein interaction databases

BioGridⁱ	129739, 2 interactors
STRINGⁱ	9606.ENSP00000310031

Structureⁱ

3D structure databases

ProteinModelPortalⁱ	Q8N9R6
SMRⁱ	Q8N9R6
ModBaseⁱ	Search...
MobiDBⁱ	Search...

Family & Domainsⁱ

Phylogenomic databases

eggNOGⁱ	ENOG410IZX3 Eukaryota ENOG41117EI LUCA
HOGENOMⁱ	HOG000111502
HOVERGENⁱ	HBG098196
InParanoidⁱ	Q8N9R6
PhylomeDBⁱ	Q8N9R6
TreeFamⁱ	TF338166

Family and domain databases

InterProⁱ	View protein in InterPro IPR029185 CDRT4
PANTHERⁱ	PTHR37885 PTHR37885, 1 hit
Pfam protein domain database More...Pfamⁱ	View protein in Pfam PF15213 CDRT4, 1 hit

Sequenceⁱ

Sequence statusⁱ: Complete.

Q8N9R6-1 [UniParc]FASTA Add to basket

« Hide

        10         20         30         40         50
MDARRMKKEG LTENTGLPRK LLEKHDPWPA YVTYTSQTVK RLIEKSKTRE 
        60         70         80         90        100
LECMRALEER PWASRQNKPS SVIQPKRRKS SKSSGKAVFR DTLSESTLSM 
       110        120        130        140        150
WGAYSVLAMA PTMIPEPTHL HADSRDCPTE NYNKIIFARK PMMRMLPTVR 

Y

Length:151

Mass (Da):17,514

Last modified:May 18, 2010 - v2

Checksum:ⁱE94DF3BE28A1A7B4

GO

Experimental Info

Feature key	Position(s)	DescriptionActions	Length
Sequence conflictⁱ	8	K → KE in BAC04263 (PubMed:14702039).Curated	1
Sequence conflictⁱ	8	K → KE in EAW89938 (Ref. 3) Curated	1
Sequence conflictⁱ	8	K → KE in AAH29542 (PubMed:15489334).Curated	1

Natural variant

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Natural variantⁱVAR_038119	72	V → I. Corresponds to variant dbSNP:rs3744332Ensembl.		1
Natural variantⁱVAR_038120	121	H → Q. Corresponds to variant dbSNP:rs2954759Ensembl.		1

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	AK093993 mRNA Translation: BAC04263.1 AC005517 Genomic DNA No translation available. CH471108 Genomic DNA Translation: EAW89938.1 BC029542 mRNA Translation: AAH29542.2
NCBI Reference Sequences More...RefSeqⁱ	NP_001191406.1, NM_001204477.1
UniGeneⁱ	Hs.164595 Hs.731765

Genome annotation databases

Ensemblⁱ	ENST00000312177; ENSP00000310031; ENSG00000239704
GeneIDⁱ	284040
KEGGⁱ	hsa:284040

Keywords - Coding sequence diversityⁱ

Polymorphism

Protein	Similar proteins		Species	Score	Length
Q8N9R6	Uncharacterized protein		NOMLE		152
CDRT4 isoform 3		PONAB		152
CMT1A duplicated region transcript 4 protein		MACMU		152
CMT1A duplicated region transcript 4 protein		MACFA		152
CMT1A duplicated region transcript 4 protein		HUMAN		152
+3

Protein	Similar proteins		Species	Score	Length
Q8N9R6	Uncharacterized protein		NOMLE		152
CMT1A duplicated region transcript 4 protein		HUMAN		152
CDRT4 isoform 3		PONAB		152
CMT1A duplicated region transcript 4 protein		MACMU		152
CMT1A duplicated region transcript 4 protein		MACFA		152
+21

Cross-referencesⁱ

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	AK093993 mRNA Translation: BAC04263.1 AC005517 Genomic DNA No translation available. CH471108 Genomic DNA Translation: EAW89938.1 BC029542 mRNA Translation: AAH29542.2
NCBI Reference Sequences More...RefSeqⁱ	NP_001191406.1, NM_001204477.1
UniGeneⁱ	Hs.164595 Hs.731765

3D structure databases

ProteinModelPortalⁱ	Q8N9R6
SMRⁱ	Q8N9R6
ModBaseⁱ	Search...
MobiDBⁱ	Search...

Protein-protein interaction databases

BioGridⁱ	129739, 2 interactors
STRINGⁱ	9606.ENSP00000310031

Polymorphism and mutation databases

BioMutaⁱ	CDRT4
DMDMⁱ	296434438

Proteomic databases

PaxDbⁱ	Q8N9R6
PeptideAtlas More...PeptideAtlasⁱ	Q8N9R6
PRIDEⁱ	Q8N9R6
ProteomicsDBⁱ	72575

Protocols and materials databases

Structural Biology Knowledgebase	Search...

Structural Biology Knowledgebase

Search...

Genome annotation databases

Ensemblⁱ	ENST00000312177; ENSP00000310031; ENSG00000239704
GeneIDⁱ	284040
KEGGⁱ	hsa:284040

Organism-specific databases

CTDⁱ	284040
GeneCardsⁱ	CDRT4
Human Gene Nomenclature Database More...HGNCⁱ	HGNC:14383 CDRT4
Human Protein Atlas More...HPAⁱ	HPA021590
neXtProtⁱ	NX_Q8N9R6
PharmGKBⁱ	PA26340
GenAtlas: human gene database More...GenAtlasⁱ	Search...

Phylogenomic databases

eggNOGⁱ	ENOG410IZX3 Eukaryota ENOG41117EI LUCA
HOGENOMⁱ	HOG000111502
HOVERGENⁱ	HBG098196
InParanoidⁱ	Q8N9R6
PhylomeDBⁱ	Q8N9R6
TreeFamⁱ	TF338166

Miscellaneous databases

GenomeRNAiⁱ	284040
Protein Ontology More...PROⁱ	PR:Q8N9R6

Gene expression databases

CleanExⁱ	HS_CDRT4

CleanExⁱ

HS_CDRT4

Family and domain databases

InterProⁱ	View protein in InterPro IPR029185 CDRT4
PANTHERⁱ	PTHR37885 PTHR37885, 1 hit
Pfam protein domain database More...Pfamⁱ	View protein in Pfam PF15213 CDRT4, 1 hit
ProtoNetⁱ	Search...

Entry informationⁱ

Entry nameⁱ	CDRT4_HUMAN
Accessionⁱ	Q8N9R6Primary (citable) accession number: Q8N9R6 Secondary accession number(s): A8MSL9, Q8IZ19
Entry historyⁱ	Integrated into UniProtKB/Swiss-Prot:	January 15, 2008
	Last sequence update:	May 18, 2010
	Last modified:	June 20, 2018
	This is version 107 of the entry and version 2 of the sequence. See complete history.
Entry statusⁱ	Reviewed (UniProtKB/Swiss-Prot)
Annotation program	Chordata Protein Annotation Program
Disclaimer	Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousⁱ

Keywords - Technical termⁱ

Complete proteome, Reference proteome

Documents

Human chromosome 17
Human chromosome 17: entries, gene names and cross-references to MIM
Human entries with polymorphisms or disease mutations
List of human entries with polymorphisms or disease mutations
Human polymorphisms and disease mutations
Index of human polymorphisms and disease mutations

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Supporting data

UniProtKB - Q8N9R6 (CDRT4_HUMAN)

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CMT1A duplicated region transcript 4 protein

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<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

Organism-specific databases

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

Polymorphism and mutation databases

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Proteomic databases

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Organism-specific databases

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Phylogenomic databases

Family and domain databases

Experimental Info

Natural variant

Sequence databases

Genome annotation databases

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

3D structure databases

Protein-protein interaction databases

Polymorphism and mutation databases

Proteomic databases

Protocols and materials databases

Genome annotation databases

Organism-specific databases

Phylogenomic databases

Miscellaneous databases

Gene expression databases

Family and domain databases

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Documents

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Names & Taxonomyⁱ

Pathology & Biotechⁱ

PTM / Processingⁱ

Expressionⁱ

Interactionⁱ

Structureⁱ

Family & Domainsⁱ

Cross-referencesⁱ

Entry informationⁱ

Miscellaneousⁱ