UniProtKB - Q8N9M1 (CS047_HUMAN)

BLAST

>sp|Q8N9M1|CS047_HUMAN Uncharacterized protein C19orf47 OS=Homo sapiens OX=9606 GN=C19orf47 PE=1 SV=1
MVMAALSLVAACWGRAAADESVQLPAAPGSSVRARETMVSVTMATSEWIQFFKEAGIPPG
PAVNYAVMFVDNRIQKSMLLDLNKEIMNELGVTVVGDIIAILKHAKVVHRQDMCKAATES
VPCSPSPLAGEIRRGTSAASRMITNSLNHDSPPSTPPRRPDTSTSKISVTVSNKMAAKSA
KATAALARREEESLAVPAKRRRVTAEMEGKYVINMPKGTTPRTRKILEQQQAAKGLHRTS
VFDRLGAETKADTTTGSKPTGVFSRLGATPETDEDLAWDSDNDSSSSVLQYAGVLKKLGR
GPAKASPQPALTVKAKATSSATTAAAPTLRRLALSSRSGLERKPESLSKVSIIKRLGAAA
LVPEAQDSQVTSTKSKSSAEVKVTIKRTLVGPRGSSSSEGLGAQMDHAGTVSVFKRLGRR
TF

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History
Entry version 116 (07 Nov 2018)
Sequence version 1 (01 Oct 2002)
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Protein

Uncharacterized protein C19orf47

Gene

C19orf47

Organism

Homo sapiens (Human)

Status

Reviewed-Annotation score: -Experimental evidence at protein levelⁱ

Names & Taxonomyⁱ

Protein namesⁱ	Recommended name: Uncharacterized protein C19orf47
Gene namesⁱ	Name:C19orf47
Organismⁱ	Homo sapiens (Human)
Taxonomic identifierⁱ	9606 [NCBI]
Taxonomic lineageⁱ	cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Dipnotetrapodomorpha › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Boreoeutheria › Euarchontoglires › Primates › Haplorrhini › Simiiformes › Catarrhini › Hominoidea › Hominidae › Homininae › Homo
Proteomesⁱ	UP000005640 Componentⁱ: Chromosome 19

Organism-specific databases

EuPathDBⁱ	HostDB:ENSG00000160392.13
Human Gene Nomenclature Database More...HGNCⁱ	HGNC:26723 C19orf47
neXtProtⁱ	NX_Q8N9M1

Subcellular locationⁱ

GO - Cellular component

Pathology & Biotechⁱ

Organism-specific databases

Open Targets More...OpenTargetsⁱ	ENSG00000160392
PharmGKBⁱ	PA145149543

Polymorphism and mutation databases

BioMutaⁱ	C19orf47
DMDMⁱ	74729722

PTM / Processingⁱ

Molecule processing

Feature key	Position(s)	DescriptionActions	Graphical view	Length
ChainⁱPRO_0000291860	1 – 422	Uncharacterized protein C19orf47Add BLAST		422

Amino acid modifications

Feature key	Position(s)	DescriptionActions	Length
Modified residueⁱ	124	PhosphoserineCombined sources	1
Modified residueⁱ	126	PhosphoserineCombined sources	1
Modified residueⁱ	151	PhosphoserineCombined sources	1
Cross-linkⁱ	250	Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)Combined sources
Modified residueⁱ	280	PhosphoserineCombined sources	1
Modified residueⁱ	306	PhosphoserineCombined sources	1
Modified residueⁱ	351	PhosphoserineCombined sources	1

Keywords - PTMⁱ

Isopeptide bond, Phosphoprotein, Ubl conjugation

Proteomic databases

EPDⁱ	Q8N9M1
MaxQB - The MaxQuant DataBase More...MaxQBⁱ	Q8N9M1
PaxDbⁱ	Q8N9M1
PeptideAtlas More...PeptideAtlasⁱ	Q8N9M1
PRIDEⁱ	Q8N9M1
ProteomicsDBⁱ	72556 72557 [Q8N9M1-2] 72558 [Q8N9M1-3]

PTM databases

iPTMnetⁱ	Q8N9M1
PhosphoSitePlusⁱ	Q8N9M1

Expressionⁱ

Gene expression databases

Bgeeⁱ	ENSG00000160392 Expressed in 117 organ(s), highest expression level in gastrocnemius
CleanExⁱ	HS_C19orf47
ExpressionAtlasⁱ	Q8N9M1 baseline and differential
Genevisibleⁱ	Q8N9M1 HS

Organism-specific databases

Human Protein Atlas More...HPAⁱ	HPA041843 HPA046309

HPAⁱ

HPA041843
HPA046309

Interactionⁱ

Binary interactionsⁱ

With	Entry	#Exp.	IntAct	Notes
NTM	Q9P121	3	EBI-2835503,EBI-4315078

With

Entry

#Exp.

IntAct

Notes

NTM

Q9P121

EBI-2835503,EBI-4315078

Protein-protein interaction databases

BioGridⁱ	125997, 12 interactors
IntActⁱ	Q8N9M1, 12 interactors
STRINGⁱ	9606.ENSP00000463159

Structureⁱ

3D structure databases

ProteinModelPortalⁱ	Q8N9M1
ModBaseⁱ	Search...
MobiDBⁱ	Search...

Family & Domainsⁱ

Compositional bias

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Compositional biasⁱ	284 – 287	Poly-Ser		4
Compositional biasⁱ	395 – 398	Poly-Ser		4

Phylogenomic databases

eggNOGⁱ	KOG3930 Eukaryota ENOG41121VM LUCA
Ensembl GeneTree More...GeneTreeⁱ	ENSGT00390000005773
HOGENOMⁱ	HOG000111994
HOVERGENⁱ	HBG061253
InParanoidⁱ	Q8N9M1
OMAⁱ	SKDIMMD
Database of Orthologous Groups More...OrthoDBⁱ	EOG091G0MLD
PhylomeDBⁱ	Q8N9M1
TreeFamⁱ	TF317361

Family and domain databases

InterProⁱ	View protein in InterPro IPR039161 C19orf47-like IPR013761 SAM/pointed_sf
PANTHERⁱ	PTHR21359 PTHR21359, 1 hit
SUPFAMⁱ	SSF47769 SSF47769, 1 hit

Sequences (3+)ⁱ

Sequence statusⁱ: Complete.

This entry describes 3 isoformsⁱ produced by alternative splicing. Align Add to basket

This entry has 3 described isoforms and 6 potential isoforms that are computationally mapped.Show all Align All

Isoform 1 (identifier: Q8N9M1-1) [UniParc]FASTA Add to basket

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide

        10         20         30         40         50
MVMAALSLVA ACWGRAAADE SVQLPAAPGS SVRARETMVS VTMATSEWIQ 
        60         70         80         90        100
FFKEAGIPPG PAVNYAVMFV DNRIQKSMLL DLNKEIMNEL GVTVVGDIIA 
       110        120        130        140        150
ILKHAKVVHR QDMCKAATES VPCSPSPLAG EIRRGTSAAS RMITNSLNHD 
       160        170        180        190        200
SPPSTPPRRP DTSTSKISVT VSNKMAAKSA KATAALARRE EESLAVPAKR 
       210        220        230        240        250
RRVTAEMEGK YVINMPKGTT PRTRKILEQQ QAAKGLHRTS VFDRLGAETK 
       260        270        280        290        300
ADTTTGSKPT GVFSRLGATP ETDEDLAWDS DNDSSSSVLQ YAGVLKKLGR 
       310        320        330        340        350
GPAKASPQPA LTVKAKATSS ATTAAAPTLR RLALSSRSGL ERKPESLSKV 
       360        370        380        390        400
SIIKRLGAAA LVPEAQDSQV TSTKSKSSAE VKVTIKRTLV GPRGSSSSEG 
       410        420 
LGAQMDHAGT VSVFKRLGRR TF

Length:422

Mass (Da):44,746

Last modified:October 1, 2002 - v1

Checksum:ⁱEA532718B56E24DE

Isoform 2 (identifier: Q8N9M1-2) [UniParc]FASTA Add to basket

The sequence of this isoform differs from the canonical sequence as follows:
1-67: Missing.

« Hide

        10         20         30         40         50
MFVDNRIQKS MLLDLNKEIM NELGVTVVGD IIAILKHAKV VHRQDMCKAA 
        60         70         80         90        100
TESVPCSPSP LAGEIRRGTS AASRMITNSL NHDSPPSTPP RRPDTSTSKI 
       110        120        130        140        150
SVTVSNKMAA KSAKATAALA RREEESLAVP AKRRRVTAEM EGKYVINMPK 
       160        170        180        190        200
GTTPRTRKIL EQQQAAKGLH RTSVFDRLGA ETKADTTTGS KPTGVFSRLG 
       210        220        230        240        250
ATPETDEDLA WDSDNDSSSS VLQYAGVLKK LGRGPAKASP QPALTVKAKA 
       260        270        280        290        300
TSSATTAAAP TLRRLALSSR SGLERKPESL SKVSIIKRLG AAALVPEAQD 
       310        320        330        340        350
SQVTSTKSKS SAEVKVTIKR TLVGPRGSSS SEGLGAQMDH AGTVSVFKRL 

GRRTF

Show »

Length:355

Mass (Da):37,796

Checksum:ⁱF0B0FD9EDF147BF0

Isoform 3 (identifier: Q8N9M1-3) [UniParc]FASTA Add to basket

The sequence of this isoform differs from the canonical sequence as follows:
1-141: Missing.

« Hide

        10         20         30         40         50
MITNSLNHDS PPSTPPRRPD TSTSKISVTV SNKMAAKSAK ATAALARREE 
        60         70         80         90        100
ESLAVPAKRR RVTAEMEGKY VINMPKGTTP RTRKILEQQQ AAKGLHRTSV 
       110        120        130        140        150
FDRLGAETKA DTTTGSKPTG VFSRLGATPE TDEDLAWDSD NDSSSSVLQY 
       160        170        180        190        200
AGVLKKLGRG PAKASPQPAL TVKAKATSSA TTAAAPTLRR LALSSRSGLE 
       210        220        230        240        250
RKPESLSKVS IIKRLGAAAL VPEAQDSQVT STKSKSSAEV KVTIKRTLVG 
       260        270        280 
PRGSSSSEGL GAQMDHAGTV SVFKRLGRRT F

Show »

Length:281

Mass (Da):29,752

Checksum:ⁱ21A265A1F298E6A4

Computationally mapped potential isoform sequencesⁱ

There are 6 potential isoforms mapped to this entry.BLAST Align Show all Add to basket

Entry	Entry name	Protein names	Gene names	Length	Annotation

J3QS16	J3QS16_HUMAN	Uncharacterized protein C19orf47 Uncharacterized protein C19orf47	C19orf47	146	Annotation score:
J3QKZ5	J3QKZ5_HUMAN	Uncharacterized protein C19orf47 Uncharacterized protein C19orf47	C19orf47	142	Annotation score:
J3QS80	J3QS80_HUMAN	Uncharacterized protein C19orf47 Uncharacterized protein C19orf47	C19orf47	168	Annotation score:
J3QKY6	J3QKY6_HUMAN	Uncharacterized protein C19orf47 Uncharacterized protein C19orf47	C19orf47	141	Annotation score:
J9JIE4	J9JIE4_HUMAN	Uncharacterized protein C19orf47 Uncharacterized protein C19orf47	C19orf47	146	Annotation score:
A0A2R8Y6U9	A0A2R8Y6U9_HUMAN	Uncharacterized protein C19orf47 Uncharacterized protein C19orf47	C19orf47	133	Annotation score:

Alternative sequence

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Alternative sequenceⁱVSP_026276	1 – 141	Missing in isoform 3. 1 PublicationAdd BLAST		141
Alternative sequenceⁱVSP_026275	1 – 67	Missing in isoform 2. 2 PublicationsAdd BLAST		67

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	AK094207 mRNA Translation: BAC04311.1 AL834131 mRNA Translation: CAD38848.1 BC023623 mRNA Translation: AAH23623.1 BC027935 mRNA Translation: AAH27935.1
The Consensus CDS (CCDS) project More...CCDSⁱ	CCDS58662.1 [Q8N9M1-1]
NCBI Reference Sequences More...RefSeqⁱ	NP_001243369.1, NM_001256440.1 [Q8N9M1-1] NP_001243370.1, NM_001256441.1 XP_016881784.1, XM_017026295.1 [Q8N9M1-3]
UniGeneⁱ	Hs.631557

Genome annotation databases

Ensemblⁱ	ENST00000392035; ENSP00000375889; ENSG00000160392 [Q8N9M1-2] ENST00000582783; ENSP00000463159; ENSG00000160392 [Q8N9M1-1]
GeneIDⁱ	126526
KEGGⁱ	hsa:126526
UCSC genome browser More...UCSCⁱ	uc002onh.5 human [Q8N9M1-1]

Keywords - Coding sequence diversityⁱ

Alternative splicing

Protein	Similar proteins		Species	Score	Length	Source
Q8N9M1	C19orf47 isoform 3		PONAB		355	UniRef100_Q8N9M1
Isoform 2 of Uncharacterized protein C19orf47		HUMAN		355
Isoform 3 of Uncharacterized protein C19orf47		HUMAN		281
Uncharacterized protein C19orf47 (Fragment)		HUMAN		142
C19orf47 isoform 8 (Fragment)		PONAB		142
+2

Protein	Similar proteins		Species	Score	Length	Source
Q8N9M1	C19orf47 isoform 3		PONAB		355	UniRef90_Q8N9M1
Isoform 2 of Uncharacterized protein C19orf47		HUMAN		355
Uncharacterized protein		MACMU		463
Uncharacterized protein		SHEEP		424
Chromosome 19 open reading frame 47		SAIBB		424
+100

Protein	Similar proteins		Species	Score	Length	Source
Q8N9M1	C19orf47 isoform 3		PONAB		355	UniRef50_Q8N9M1
Isoform 2 of Uncharacterized protein C19orf47		HUMAN		355
Uncharacterized protein		MACMU		463
Uncharacterized protein		SHEEP		424
Chromosome 19 open reading frame 47		SAIBB		424
+191

Cross-referencesⁱ

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	AK094207 mRNA Translation: BAC04311.1 AL834131 mRNA Translation: CAD38848.1 BC023623 mRNA Translation: AAH23623.1 BC027935 mRNA Translation: AAH27935.1
CCDSⁱ	CCDS58662.1 [Q8N9M1-1]
RefSeqⁱ	NP_001243369.1, NM_001256440.1 [Q8N9M1-1] NP_001243370.1, NM_001256441.1 XP_016881784.1, XM_017026295.1 [Q8N9M1-3]
UniGeneⁱ	Hs.631557

3D structure databases

ProteinModelPortalⁱ	Q8N9M1
ModBaseⁱ	Search...
MobiDBⁱ	Search...

Protein-protein interaction databases

BioGridⁱ	125997, 12 interactors
IntActⁱ	Q8N9M1, 12 interactors
STRINGⁱ	9606.ENSP00000463159

PTM databases

iPTMnetⁱ	Q8N9M1
PhosphoSitePlusⁱ	Q8N9M1

Polymorphism and mutation databases

BioMutaⁱ	C19orf47
DMDMⁱ	74729722

Proteomic databases

EPDⁱ	Q8N9M1
MaxQBⁱ	Q8N9M1
PaxDbⁱ	Q8N9M1
PeptideAtlasⁱ	Q8N9M1
PRIDEⁱ	Q8N9M1
ProteomicsDBⁱ	72556 72557 [Q8N9M1-2] 72558 [Q8N9M1-3]

Protocols and materials databases

The DNASU plasmid repository More...DNASUⁱ	126526
Structural Biology Knowledgebase	Search...

Genome annotation databases

Ensemblⁱ	ENST00000392035; ENSP00000375889; ENSG00000160392 [Q8N9M1-2] ENST00000582783; ENSP00000463159; ENSG00000160392 [Q8N9M1-1]
GeneIDⁱ	126526
KEGGⁱ	hsa:126526
UCSCⁱ	uc002onh.5 human [Q8N9M1-1]

Organism-specific databases

CTDⁱ	126526
EuPathDBⁱ	HostDB:ENSG00000160392.13
GeneCardsⁱ	C19orf47
H-InvDBⁱ	HIX0202777
HGNCⁱ	HGNC:26723 C19orf47
HPAⁱ	HPA041843 HPA046309
neXtProtⁱ	NX_Q8N9M1
OpenTargetsⁱ	ENSG00000160392
PharmGKBⁱ	PA145149543
GenAtlas: human gene database More...GenAtlasⁱ	Search...

Phylogenomic databases

eggNOGⁱ	KOG3930 Eukaryota ENOG41121VM LUCA
GeneTreeⁱ	ENSGT00390000005773
HOGENOMⁱ	HOG000111994
HOVERGENⁱ	HBG061253
InParanoidⁱ	Q8N9M1
OMAⁱ	SKDIMMD
OrthoDBⁱ	EOG091G0MLD
PhylomeDBⁱ	Q8N9M1
TreeFamⁱ	TF317361

Miscellaneous databases

ChiTaRSⁱ	C19orf47 human
GenomeRNAiⁱ	126526
Protein Ontology More...PROⁱ	PR:Q8N9M1

Gene expression databases

Bgeeⁱ	ENSG00000160392 Expressed in 117 organ(s), highest expression level in gastrocnemius
CleanExⁱ	HS_C19orf47
ExpressionAtlasⁱ	Q8N9M1 baseline and differential
Genevisibleⁱ	Q8N9M1 HS

Family and domain databases

InterProⁱ	View protein in InterPro IPR039161 C19orf47-like IPR013761 SAM/pointed_sf
PANTHERⁱ	PTHR21359 PTHR21359, 1 hit
SUPFAMⁱ	SSF47769 SSF47769, 1 hit
ProtoNetⁱ	Search...

Entry informationⁱ

Entry nameⁱ	CS047_HUMAN
Accessionⁱ	Q8N9M1Primary (citable) accession number: Q8N9M1 Secondary accession number(s): Q8IZ33, Q8N0V9
Entry historyⁱ	Integrated into UniProtKB/Swiss-Prot:	June 26, 2007
	Last sequence update:	October 1, 2002
	Last modified:	November 7, 2018
	This is version 116 of the entry and version 1 of the sequence. See complete history.
Entry statusⁱ	Reviewed (UniProtKB/Swiss-Prot)
Annotation program	Chordata Protein Annotation Program
Disclaimer	Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousⁱ

Keywords - Technical termⁱ

Complete proteome, Reference proteome

Documents

Human chromosome 19
Human chromosome 19: entries, gene names and cross-references to MIM

UniProtKB

UniParc

Help

UniRef

Proteomes

Annotation systems

Supporting data

UniProtKB - Q8N9M1 (CS047_HUMAN)

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Uncharacterized protein C19orf47

C19orf47

Select a section on the left to see content.

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

Organism-specific databases

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Nucleus

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

Polymorphism and mutation databases

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Amino acid modifications

Proteomic databases

PTM databases

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Organism-specific databases

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Compositional bias

Phylogenomic databases

Family and domain databases

Alternative sequence

Sequence databases

Genome annotation databases

Keywords - Coding sequence diversityi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

3D structure databases

Protein-protein interaction databases

PTM databases

Polymorphism and mutation databases

Proteomic databases

Protocols and materials databases

Genome annotation databases

Organism-specific databases

Phylogenomic databases

Miscellaneous databases

Gene expression databases

Family and domain databases

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Documents

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Names & Taxonomyⁱ

Subcellular locationⁱ

Pathology & Biotechⁱ

PTM / Processingⁱ

Expressionⁱ

Interactionⁱ

Structureⁱ

Family & Domainsⁱ

Keywords - Coding sequence diversityⁱ

Cross-referencesⁱ

Entry informationⁱ

Miscellaneousⁱ

Keywords - Technical termⁱ