UniProtKB - Q8N9M1 (CS047_HUMAN)
Protein
Uncharacterized protein C19orf47
Gene
C19orf47
Organism
Homo sapiens (Human)
Status
Names & Taxonomyi
Protein namesi | Recommended name: Uncharacterized protein C19orf47 |
Gene namesi | Name:C19orf47 |
Organismi | Homo sapiens (Human) |
Taxonomic identifieri | 9606 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo |
Proteomesi |
|
Organism-specific databases
HGNCi | HGNC:26723, C19orf47 |
neXtProti | NX_Q8N9M1 |
VEuPathDBi | HostDB:ENSG00000160392.13 |
Pathology & Biotechi
Organism-specific databases
DisGeNETi | 126526 |
OpenTargetsi | ENSG00000160392 |
PharmGKBi | PA145149543 |
Miscellaneous databases
Pharosi | Q8N9M1, Tdark |
Genetic variation databases
BioMutai | C19orf47 |
DMDMi | 74729722 |
PTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
ChainiPRO_0000291860 | 1 – 422 | Uncharacterized protein C19orf47Add BLAST | 422 |
Amino acid modifications
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Modified residuei | 124 | PhosphoserineCombined sources | 1 | |
Modified residuei | 126 | PhosphoserineCombined sources | 1 | |
Modified residuei | 151 | PhosphoserineCombined sources | 1 | |
Cross-linki | 250 | Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)Combined sources | ||
Modified residuei | 280 | PhosphoserineCombined sources | 1 | |
Modified residuei | 306 | PhosphoserineCombined sources | 1 | |
Modified residuei | 351 | PhosphoserineCombined sources | 1 |
Keywords - PTMi
Isopeptide bond, Phosphoprotein, Ubl conjugationProteomic databases
EPDi | Q8N9M1 |
jPOSTi | Q8N9M1 |
MassIVEi | Q8N9M1 |
MaxQBi | Q8N9M1 |
PaxDbi | Q8N9M1 |
PeptideAtlasi | Q8N9M1 |
PRIDEi | Q8N9M1 |
ProteomicsDBi | 72556 [Q8N9M1-1] 72557 [Q8N9M1-2] 72558 [Q8N9M1-3] |
PTM databases
iPTMneti | Q8N9M1 |
PhosphoSitePlusi | Q8N9M1 |
Expressioni
Gene expression databases
Bgeei | ENSG00000160392, Expressed in gastrocnemius and 136 other tissues |
ExpressionAtlasi | Q8N9M1, baseline and differential |
Genevisiblei | Q8N9M1, HS |
Organism-specific databases
HPAi | ENSG00000160392, Tissue enhanced (heart muscle, skeletal muscle) |
Interactioni
Binary interactionsi
Hide detailsQ8N9M1
With | #Exp. | IntAct |
---|---|---|
NTM [Q9P121] | 3 | EBI-2835503,EBI-4315078 |
Isoform 2 [Q8N9M1-2]
With | #Exp. | IntAct |
---|---|---|
GSC2 [O15499] | 3 | EBI-10979594,EBI-19954058 |
PSMA6 [P60900] | 3 | EBI-10979594,EBI-357793 |
Protein-protein interaction databases
BioGRIDi | 125997, 22 interactors |
IntActi | Q8N9M1, 12 interactors |
STRINGi | 9606.ENSP00000463159 |
Miscellaneous databases
RNActi | Q8N9M1, protein |
Family & Domainsi
Compositional bias
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Compositional biasi | 284 – 287 | Poly-Ser | 4 | |
Compositional biasi | 395 – 398 | Poly-Ser | 4 |
Phylogenomic databases
eggNOGi | KOG3930, Eukaryota |
GeneTreei | ENSGT00390000005773 |
HOGENOMi | CLU_047260_0_0_1 |
InParanoidi | Q8N9M1 |
OMAi | DHRIQKN |
OrthoDBi | 1034351at2759 |
PhylomeDBi | Q8N9M1 |
TreeFami | TF317361 |
Family and domain databases
CDDi | cd09531, SAM_CS047, 1 hit |
Gene3Di | 1.10.150.50, 1 hit |
InterProi | View protein in InterPro IPR039161, C19orf47-like IPR040772, C19orf47_SAM IPR041477, DUF5577 IPR013761, SAM/pointed_sf |
PANTHERi | PTHR21359, PTHR21359, 1 hit |
Pfami | View protein in Pfam PF17740, DUF5577, 1 hit |
SUPFAMi | SSF47769, SSF47769, 1 hit |
s (3+)i Sequence
Sequence statusi: Complete.
This entry describes 3 produced by isoformsialternative splicing. AlignAdd to basketThis entry has 3 described isoforms and 6 potential isoforms that are computationally mapped.Show allAlign All
Isoform 1 (identifier: Q8N9M1-1) [UniParc]FASTAAdd to basket
This isoform has been chosen as the sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry. canonicali
10 20 30 40 50
MVMAALSLVA ACWGRAAADE SVQLPAAPGS SVRARETMVS VTMATSEWIQ
60 70 80 90 100
FFKEAGIPPG PAVNYAVMFV DNRIQKSMLL DLNKEIMNEL GVTVVGDIIA
110 120 130 140 150
ILKHAKVVHR QDMCKAATES VPCSPSPLAG EIRRGTSAAS RMITNSLNHD
160 170 180 190 200
SPPSTPPRRP DTSTSKISVT VSNKMAAKSA KATAALARRE EESLAVPAKR
210 220 230 240 250
RRVTAEMEGK YVINMPKGTT PRTRKILEQQ QAAKGLHRTS VFDRLGAETK
260 270 280 290 300
ADTTTGSKPT GVFSRLGATP ETDEDLAWDS DNDSSSSVLQ YAGVLKKLGR
310 320 330 340 350
GPAKASPQPA LTVKAKATSS ATTAAAPTLR RLALSSRSGL ERKPESLSKV
360 370 380 390 400
SIIKRLGAAA LVPEAQDSQV TSTKSKSSAE VKVTIKRTLV GPRGSSSSEG
410 420
LGAQMDHAGT VSVFKRLGRR TF
Computationally mapped potential isoform sequencesi
There are 6 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basketJ3QS16 | J3QS16_HUMAN | Uncharacterized protein C19orf47 | C19orf47 | 146 | Annotation score: | ||
J3QKZ5 | J3QKZ5_HUMAN | Uncharacterized protein C19orf47 | C19orf47 | 142 | Annotation score: | ||
J3QS80 | J3QS80_HUMAN | Uncharacterized protein C19orf47 | C19orf47 | 168 | Annotation score: | ||
J3QKY6 | J3QKY6_HUMAN | Uncharacterized protein C19orf47 | C19orf47 | 141 | Annotation score: | ||
A0A2R8Y6U9 | A0A2R8Y6U9_HUMAN | Uncharacterized protein C19orf47 | C19orf47 | 133 | Annotation score: | ||
J9JIE4 | J9JIE4_HUMAN | Uncharacterized protein C19orf47 | C19orf47 | 146 | Annotation score: |
Alternative sequence
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Alternative sequenceiVSP_026276 | 1 – 141 | Missing in isoform 3. 1 PublicationAdd BLAST | 141 | |
Alternative sequenceiVSP_026275 | 1 – 67 | Missing in isoform 2. 2 PublicationsAdd BLAST | 67 |
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AK094207 mRNA Translation: BAC04311.1 AL834131 mRNA Translation: CAD38848.1 BC023623 mRNA Translation: AAH23623.1 BC027935 mRNA Translation: AAH27935.1 |
CCDSi | CCDS58662.1 [Q8N9M1-1] |
RefSeqi | NP_001243369.1, NM_001256440.1 [Q8N9M1-1] NP_001243370.1, NM_001256441.1 XP_016881784.1, XM_017026295.1 [Q8N9M1-3] |
Genome annotation databases
Ensembli | ENST00000392035; ENSP00000375889; ENSG00000160392 [Q8N9M1-2] ENST00000582783; ENSP00000463159; ENSG00000160392 [Q8N9M1-1] |
GeneIDi | 126526 |
KEGGi | hsa:126526 |
UCSCi | uc002onh.5, human [Q8N9M1-1] |
Keywords - Coding sequence diversityi
Alternative splicingSimilar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AK094207 mRNA Translation: BAC04311.1 AL834131 mRNA Translation: CAD38848.1 BC023623 mRNA Translation: AAH23623.1 BC027935 mRNA Translation: AAH27935.1 |
CCDSi | CCDS58662.1 [Q8N9M1-1] |
RefSeqi | NP_001243369.1, NM_001256440.1 [Q8N9M1-1] NP_001243370.1, NM_001256441.1 XP_016881784.1, XM_017026295.1 [Q8N9M1-3] |
3D structure databases
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Protein-protein interaction databases
BioGRIDi | 125997, 22 interactors |
IntActi | Q8N9M1, 12 interactors |
STRINGi | 9606.ENSP00000463159 |
PTM databases
iPTMneti | Q8N9M1 |
PhosphoSitePlusi | Q8N9M1 |
Genetic variation databases
BioMutai | C19orf47 |
DMDMi | 74729722 |
Proteomic databases
EPDi | Q8N9M1 |
jPOSTi | Q8N9M1 |
MassIVEi | Q8N9M1 |
MaxQBi | Q8N9M1 |
PaxDbi | Q8N9M1 |
PeptideAtlasi | Q8N9M1 |
PRIDEi | Q8N9M1 |
ProteomicsDBi | 72556 [Q8N9M1-1] 72557 [Q8N9M1-2] 72558 [Q8N9M1-3] |
Protocols and materials databases
Antibodypediai | 30505, 108 antibodies |
DNASUi | 126526 |
Genome annotation databases
Ensembli | ENST00000392035; ENSP00000375889; ENSG00000160392 [Q8N9M1-2] ENST00000582783; ENSP00000463159; ENSG00000160392 [Q8N9M1-1] |
GeneIDi | 126526 |
KEGGi | hsa:126526 |
UCSCi | uc002onh.5, human [Q8N9M1-1] |
Organism-specific databases
CTDi | 126526 |
DisGeNETi | 126526 |
GeneCardsi | C19orf47 |
HGNCi | HGNC:26723, C19orf47 |
HPAi | ENSG00000160392, Tissue enhanced (heart muscle, skeletal muscle) |
neXtProti | NX_Q8N9M1 |
OpenTargetsi | ENSG00000160392 |
PharmGKBi | PA145149543 |
VEuPathDBi | HostDB:ENSG00000160392.13 |
GenAtlasi | Search... |
Phylogenomic databases
eggNOGi | KOG3930, Eukaryota |
GeneTreei | ENSGT00390000005773 |
HOGENOMi | CLU_047260_0_0_1 |
InParanoidi | Q8N9M1 |
OMAi | DHRIQKN |
OrthoDBi | 1034351at2759 |
PhylomeDBi | Q8N9M1 |
TreeFami | TF317361 |
Enzyme and pathway databases
PathwayCommonsi | Q8N9M1 |
Miscellaneous databases
BioGRID-ORCSi | 126526, 6 hits in 980 CRISPR screens |
ChiTaRSi | C19orf47, human |
GenomeRNAii | 126526 |
Pharosi | Q8N9M1, Tdark |
PROi | PR:Q8N9M1 |
RNActi | Q8N9M1, protein |
Gene expression databases
Bgeei | ENSG00000160392, Expressed in gastrocnemius and 136 other tissues |
ExpressionAtlasi | Q8N9M1, baseline and differential |
Genevisiblei | Q8N9M1, HS |
Family and domain databases
CDDi | cd09531, SAM_CS047, 1 hit |
Gene3Di | 1.10.150.50, 1 hit |
InterProi | View protein in InterPro IPR039161, C19orf47-like IPR040772, C19orf47_SAM IPR041477, DUF5577 IPR013761, SAM/pointed_sf |
PANTHERi | PTHR21359, PTHR21359, 1 hit |
Pfami | View protein in Pfam PF17740, DUF5577, 1 hit |
SUPFAMi | SSF47769, SSF47769, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | CS047_HUMAN | |
Accessioni | Q8N9M1Primary (citable) accession number: Q8N9M1 Secondary accession number(s): Q8IZ33, Q8N0V9 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | June 26, 2007 |
Last sequence update: | October 1, 2002 | |
Last modified: | April 7, 2021 | |
This is version 131 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Chordata Protein Annotation Program | |
Disclaimer | Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. |
Miscellaneousi
Keywords - Technical termi
Reference proteomeDocuments
- Human chromosome 19
Human chromosome 19: entries, gene names and cross-references to MIM