UniProtKB - Q8N9E0 (F133A_HUMAN)
Protein
Protein FAM133A
Gene
FAM133A
Organism
Homo sapiens (Human)
Status
Names & Taxonomyi
Protein namesi | Recommended name: Protein FAM133A |
Gene namesi | Name:FAM133A |
Organismi | Homo sapiens (Human) |
Taxonomic identifieri | 9606 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo |
Proteomesi |
|
Organism-specific databases
HGNCi | HGNC:26748, FAM133A |
neXtProti | NX_Q8N9E0 |
VEuPathDBi | HostDB:ENSG00000179083.6 |
Pathology & Biotechi
Organism-specific databases
DisGeNETi | 286499 |
OpenTargetsi | ENSG00000179083 |
PharmGKBi | PA162386125 |
Miscellaneous databases
Pharosi | Q8N9E0, Tdark |
Genetic variation databases
BioMutai | FAM133A |
DMDMi | 74751120 |
PTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
ChainiPRO_0000287619 | 1 – 248 | Protein FAM133AAdd BLAST | 248 |
Proteomic databases
EPDi | Q8N9E0 |
MassIVEi | Q8N9E0 |
MaxQBi | Q8N9E0 |
PaxDbi | Q8N9E0 |
PeptideAtlasi | Q8N9E0 |
PRIDEi | Q8N9E0 |
ProteomicsDBi | 72524 |
PTM databases
iPTMneti | Q8N9E0 |
PhosphoSitePlusi | Q8N9E0 |
Expressioni
Gene expression databases
Bgeei | ENSG00000179083, Expressed in buccal mucosa cell and 116 other tissues |
Genevisiblei | Q8N9E0, HS |
Organism-specific databases
HPAi | ENSG00000179083, Group enriched (brain, pituitary gland, testis) |
Interactioni
Binary interactionsi
Hide detailsQ8N9E0
Protein-protein interaction databases
BioGRIDi | 130395, 20 interactors |
IntActi | Q8N9E0, 19 interactors |
STRINGi | 9606.ENSP00000318974 |
Miscellaneous databases
RNActi | Q8N9E0, protein |
Family & Domainsi
Compositional bias
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Compositional biasi | 45 – 240 | Lys-richAdd BLAST | 196 | |
Compositional biasi | 82 – 198 | Ser-richAdd BLAST | 117 |
Sequence similaritiesi
Belongs to the FAM133 family.Curated
Phylogenomic databases
eggNOGi | ENOG502RXMT, Eukaryota |
GeneTreei | ENSGT00730000111097 |
HOGENOMi | CLU_108741_0_0_1 |
InParanoidi | Q8N9E0 |
OMAi | KTGHRRH |
OrthoDBi | 1561261at2759 |
PhylomeDBi | Q8N9E0 |
TreeFami | TF350193 |
Family and domain databases
InterProi | View protein in InterPro IPR026766, Fam133 |
PANTHERi | PTHR31911, PTHR31911, 1 hit |
i Sequence
Sequence statusi: Complete.
Q8N9E0-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MGKRDNRVAY MNPIAMARWR GPTQSVGPTI QDYLNRPRPT WEEVKKQLEN
60 70 80 90 100
KKTGSKALAE FEEKMNENWK KELEKSREKL LSGNESSSKK RERKKKRKKK
110 120 130 140 150
SCRSSSSSSS SDSSSSSSDS EDEEKKQGKR RKKKKNRSYK SSQSSTHESE
160 170 180 190 200
SESKESVKKK KKSKDETEKE KDVRSLSKKR KKSYPDDKPL SSESSSESDY
210 220 230 240
EEDVQAKKKR RCEEREQAKE KVKKKKKKQH KKHSKKKKKK SGSSHKSR
Natural variant
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Natural variantiVAR_053907 | 67 | E → K. Corresponds to variant dbSNP:rs34123774Ensembl. | 1 |
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AK094978 mRNA Translation: BAC04467.1 AL009173 Genomic DNA No translation available. BC113387 mRNA Translation: AAI13388.1 BC113385 mRNA Translation: AAI13386.1 |
CCDSi | CCDS14466.1 |
RefSeqi | NP_001164580.1, NM_001171109.1 NP_001164581.1, NM_001171110.1 NP_001164582.1, NM_001171111.1 NP_775969.1, NM_173698.2 XP_006724704.1, XM_006724641.3 XP_011529227.1, XM_011530925.2 XP_011529228.1, XM_011530926.2 XP_011529229.1, XM_011530927.2 XP_011529230.1, XM_011530928.1 XP_011529231.1, XM_011530929.1 XP_011529233.1, XM_011530931.2 XP_016884943.1, XM_017029454.1 XP_016884944.1, XM_017029455.1 XP_016884945.1, XM_017029456.1 |
Genome annotation databases
Ensembli | ENST00000322139; ENSP00000318974; ENSG00000179083 ENST00000332647; ENSP00000362169; ENSG00000179083 |
GeneIDi | 286499 |
KEGGi | hsa:286499 |
UCSCi | uc004efr.3, human |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AK094978 mRNA Translation: BAC04467.1 AL009173 Genomic DNA No translation available. BC113387 mRNA Translation: AAI13388.1 BC113385 mRNA Translation: AAI13386.1 |
CCDSi | CCDS14466.1 |
RefSeqi | NP_001164580.1, NM_001171109.1 NP_001164581.1, NM_001171110.1 NP_001164582.1, NM_001171111.1 NP_775969.1, NM_173698.2 XP_006724704.1, XM_006724641.3 XP_011529227.1, XM_011530925.2 XP_011529228.1, XM_011530926.2 XP_011529229.1, XM_011530927.2 XP_011529230.1, XM_011530928.1 XP_011529231.1, XM_011530929.1 XP_011529233.1, XM_011530931.2 XP_016884943.1, XM_017029454.1 XP_016884944.1, XM_017029455.1 XP_016884945.1, XM_017029456.1 |
3D structure databases
SMRi | Q8N9E0 |
ModBasei | Search... |
Protein-protein interaction databases
BioGRIDi | 130395, 20 interactors |
IntActi | Q8N9E0, 19 interactors |
STRINGi | 9606.ENSP00000318974 |
PTM databases
iPTMneti | Q8N9E0 |
PhosphoSitePlusi | Q8N9E0 |
Genetic variation databases
BioMutai | FAM133A |
DMDMi | 74751120 |
Proteomic databases
EPDi | Q8N9E0 |
MassIVEi | Q8N9E0 |
MaxQBi | Q8N9E0 |
PaxDbi | Q8N9E0 |
PeptideAtlasi | Q8N9E0 |
PRIDEi | Q8N9E0 |
ProteomicsDBi | 72524 |
Protocols and materials databases
Antibodypediai | 67595, 62 antibodies |
DNASUi | 286499 |
Genome annotation databases
Ensembli | ENST00000322139; ENSP00000318974; ENSG00000179083 ENST00000332647; ENSP00000362169; ENSG00000179083 |
GeneIDi | 286499 |
KEGGi | hsa:286499 |
UCSCi | uc004efr.3, human |
Organism-specific databases
CTDi | 286499 |
DisGeNETi | 286499 |
GeneCardsi | FAM133A |
HGNCi | HGNC:26748, FAM133A |
HPAi | ENSG00000179083, Group enriched (brain, pituitary gland, testis) |
neXtProti | NX_Q8N9E0 |
OpenTargetsi | ENSG00000179083 |
PharmGKBi | PA162386125 |
VEuPathDBi | HostDB:ENSG00000179083.6 |
GenAtlasi | Search... |
Phylogenomic databases
eggNOGi | ENOG502RXMT, Eukaryota |
GeneTreei | ENSGT00730000111097 |
HOGENOMi | CLU_108741_0_0_1 |
InParanoidi | Q8N9E0 |
OMAi | KTGHRRH |
OrthoDBi | 1561261at2759 |
PhylomeDBi | Q8N9E0 |
TreeFami | TF350193 |
Enzyme and pathway databases
PathwayCommonsi | Q8N9E0 |
Miscellaneous databases
BioGRID-ORCSi | 286499, 44 hits in 495 CRISPR screens |
GenomeRNAii | 286499 |
Pharosi | Q8N9E0, Tdark |
PROi | PR:Q8N9E0 |
RNActi | Q8N9E0, protein |
Gene expression databases
Bgeei | ENSG00000179083, Expressed in buccal mucosa cell and 116 other tissues |
Genevisiblei | Q8N9E0, HS |
Family and domain databases
InterProi | View protein in InterPro IPR026766, Fam133 |
PANTHERi | PTHR31911, PTHR31911, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | F133A_HUMAN | |
Accessioni | Q8N9E0Primary (citable) accession number: Q8N9E0 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | May 15, 2007 |
Last sequence update: | October 1, 2002 | |
Last modified: | February 10, 2021 | |
This is version 122 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Chordata Protein Annotation Program | |
Disclaimer | Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. |
Miscellaneousi
Keywords - Technical termi
Reference proteomeDocuments
- Uncharacterized protein families (UPF)
List of uncharacterized protein family (UPF) entries - Human chromosome X
Human chromosome X: entries, gene names and cross-references to MIM - Human entries with genetic variants
List of human entries with genetic variants - Human variants curated from literature reports
Index of human variants curated from literature reports - SIMILARITY comments
Index of protein domains and families