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UniProtKB - Q8N957 (ANKF1_HUMAN)

Entry version 132 (25 May 2022)
Sequence version 2 (24 Nov 2009)
Previous versions | rss
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Protein

Ankyrin repeat and fibronectin type-III domain-containing protein 1

Gene

ANKFN1

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>-Experimental evidence at transcript leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Biological processi

Complete GO annotation on QuickGO ...

Enzyme and pathway databases

Pathway Commons web resource for biological pathway data

More...PathwayCommonsi		Q8N957

SignaLink: a signaling pathway resource with multi-layered regulatory networks

More...SignaLinki		Q8N957

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Ankyrin repeat and fibronectin type-III domain-containing protein 1
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:ANKFN1
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 17

Organism-specific databases

Human Gene Nomenclature Database

More...HGNCi		HGNC:26766, ANKFN1

neXtProt; the human protein knowledge platform

More...neXtProti		NX_Q8N957

Eukaryotic Pathogen, Vector and Host Database Resources

More...VEuPathDBi		HostDB:ENSG00000153930

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

DisGeNET

More...DisGeNETi		162282

Open Targets

More...OpenTargetsi		ENSG00000153930

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...PharmGKBi		PA142672624

Miscellaneous databases

Pharos NIH Druggable Genome Knowledgebase

More...Pharosi		Q8N957, Tdark

Genetic variation databases

BioMuta curated single-nucleotide variation and disease association database

More...BioMutai		ANKFN1

Domain mapping of disease mutations (DMDM)

More...DMDMi		269849542

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00002471381 – 763Ankyrin repeat and fibronectin type-III domain-containing protein 1Add BLAST763

Proteomic databases

jPOST - Japan Proteome Standard Repository/Database

More...jPOSTi		Q8N957

MassIVE - Mass Spectrometry Interactive Virtual Environment

More...MassIVEi		Q8N957

PaxDb, a database of protein abundance averages across all three domains of life

More...PaxDbi		Q8N957

PeptideAtlas

More...PeptideAtlasi		Q8N957

PRoteomics IDEntifications database

More...PRIDEi		Q8N957

ProteomicsDB: a multi-organism proteome resource

More...ProteomicsDBi		72490

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...iPTMneti		Q8N957

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...PhosphoSitePlusi		Q8N957

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...Bgeei		ENSG00000153930, Expressed in buccal mucosa cell and 119 other tissues

ExpressionAtlas, Differential and Baseline Expression

More...ExpressionAtlasi		Q8N957, baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...Genevisiblei		Q8N957, HS

Organism-specific databases

Human Protein Atlas

More...HPAi		ENSG00000153930, Group enriched (brain, cervix, fallopian tube)

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

STRING: functional protein association networks

More...STRINGi		9606.ENSP00000321627

Miscellaneous databases

RNAct, Protein-RNA interaction predictions for model organisms.

More...RNActi		Q8N957, protein

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

AlphaFold Protein Structure Database

More...AlphaFoldDBi		Q8N957

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...SMRi		Q8N957

Database of comparative protein structure models

More...ModBasei		Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section indicates the positions and types of repeated sequence motifs or repeated domains within the protein.<p><a href='/help/repeat' target='_top'>More...</a></p>Repeati136 – 165ANK 1Add BLAST30
Repeati173 – 202ANK 2Add BLAST30
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini273 – 369Fibronectin type-IIIPROSITE-ProRule annotationAdd BLAST97

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and domains' section denotes the positions of regions of coiled coil within the protein.<p><a href='/help/coiled' target='_top'>More...</a></p>Coiled coili205 – 236Sequence analysisAdd BLAST32

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Domaini

ANK repeat, Coiled coil, Repeat

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...eggNOGi		KOG4485, Eukaryota

Ensembl GeneTree

More...GeneTreei		ENSGT00940000159856

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...HOGENOMi		CLU_010667_0_0_1

InParanoid: Eukaryotic Ortholog Groups

More...InParanoidi		Q8N957

Identification of Orthologs from Complete Genome Data

More...OMAi		SINWNCC

Database of Orthologous Groups

More...OrthoDBi		1305469at2759

Database for complete collections of gene phylogenies

More...PhylomeDBi		Q8N957

TreeFam database of animal gene trees

More...TreeFami		TF314968

Family and domain databases

Conserved Domains Database

More...CDDi		cd00063, FN3, 1 hit

Gene3D Structural and Functional Annotation of Protein Families

More...Gene3Di		1.25.40.20, 1 hit
2.60.40.10, 1 hit

Integrated resource of protein families, domains and functional sites

More...InterProi		View protein in InterPro
IPR039269, ANKFN1
IPR002110, Ankyrin_rpt
IPR036770, Ankyrin_rpt-contain_sf
IPR003961, FN3_dom
IPR036116, FN3_sf
IPR013783, Ig-like_fold

The PANTHER Classification System

More...PANTHERi		PTHR21437, PTHR21437, 1 hit

Pfam protein domain database

More...Pfami		View protein in Pfam
PF13637, Ank_4, 1 hit
PF00041, fn3, 1 hit

Simple Modular Architecture Research Tool; a protein domain database

More...SMARTi		View protein in SMART
SM00248, ANK, 2 hits
SM00060, FN3, 1 hit

Superfamily database of structural and functional annotation

More...SUPFAMi		SSF48403, SSF48403, 1 hit
SSF49265, SSF49265, 1 hit

PROSITE; a protein domain and family database

More...PROSITEi		View protein in PROSITE
PS50297, ANK_REP_REGION, 1 hit
PS50088, ANK_REPEAT, 1 hit
PS50853, FN3, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry has 1 described isoform and 5 potential isoforms that are computationally mapped.Show allAlign All

Q8N957-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MEASLTRRLL FKDRHFTCSK IIGRRFACFA QRLSHRRKQS QCDLLNESTG 
        60         70         80         90        100
QLPTTCSSAA SNSINWNCRV KMTQQMQNLH LCQSKKHSAP SSPNAAKRLY 
       110        120        130        140        150
RNLSEKLKGS HSSFDEAYFR TRTDRLSLRK TSVNFQGNEA MFEAVEQQDM 
       160        170        180        190        200
DAVQILLYQY TPEELDLNTP NSEGLTPLDI AIMTNNVPIA RILLRTGARE 
       210        220        230        240        250
SPHFVSLESR AMHLNTLVQE AQERVSELSA QVENEGFTLD NTEKEKQLKA 
       260        270        280        290        300
WEWRYRLYRR MKTGFEHARA PEMPTNVCLM VTSSTSLTVS FQEPLSVNAA 
       310        320        330        340        350
VVTRYKVEWS MSEDFSPLAG EIIMDNLQTL RCTITGLTMG QQYFVQVSAY 
       360        370        380        390        400
NMKGWGPAQT TTPACASPSN WKDYDDREPR HKGQSEVLEG LLQQVRALHQ 
       410        420        430        440        450
HYSCRESTKL QTTGRKQSVS RSLKHLFHSS NKFVKTLKRG LYIAVIFYYK 
       460        470        480        490        500
DNILVTNEDQ VPIVEIDDSH TSSITQDFLW FTKLSCMWED IRWLRQSIPI 
       510        520        530        540        550
SSSSSTVLQT RQKMLAATAQ LQNLLGTHNL GRVYYEPIKD RHGNILIVTI 
       560        570        580        590        600
REVEMLYSFF NGKWMQISKL QSQRKSLSTP EEPTALDILL ITIQDILSYH 
       610        620        630        640        650
KRSHQRLFPG LYLGYLKLCS SVDQIKVLVT QKLPNILCHV KIRENNNISR 
       660        670        680        690        700
EEWEWIQKLS GSESMESVDH TSDCPMQLFF YELQMAVKAL LQQINIPLHQ 
       710        720        730        740        750
ARNFRLYTQE VLEMGHNVSF LLLLPASDDV CTAPGQNNPY TPHSGFLNLP 
       760 
LQMFELGIVA CFT
Length:763
Mass (Da):87,604
Last modified:November 24, 2009 - v2
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i49174DE8572FC994
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 5 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
H3BM45H3BM45_HUMAN
Ankyrin repeat and fibronectin type...
ANKFN1
1,149Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A590UK59A0A590UK59_HUMAN
Ankyrin repeat and fibronectin type...
ANKFN1
1,296Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A804HJ58A0A804HJ58_HUMAN
Ankyrin repeat and fibronectin type...
ANKFN1
1,146Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A1B0GTR8A0A1B0GTR8_HUMAN
Ankyrin repeat and fibronectin type...
ANKFN1
494Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
I3L0N6I3L0N6_HUMAN
Ankyrin repeat and fibronectin type...
ANKFN1
173Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section describes natural variant(s) of the protein sequence.<p><a href='/help/variant' target='_top'>More...</a></p>Natural variantiVAR_060725445V → I1 PublicationCorresponds to variant dbSNP:rs10852985Ensembl.1

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...EMBLi

GenBank nucleotide sequence database

More...GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...DDBJi
Links Updated
AK095654 mRNA Translation: BAC04599.1
AC006600 Genomic DNA No translation available.
AC006925 Genomic DNA No translation available.
AC015724 Genomic DNA No translation available.

The Consensus CDS (CCDS) project

More...CCDSi		CCDS32686.1

NCBI Reference Sequences

More...RefSeqi		NP_694960.2, NM_153228.2

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...Ensembli		ENST00000318698.6; ENSP00000321627.2; ENSG00000153930.13

Database of genes from NCBI RefSeq genomes

More...GeneIDi		162282

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...KEGGi		hsa:162282

UCSC genome browser

More...UCSCi		uc002iun.1, human

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK095654 mRNA Translation: BAC04599.1
AC006600 Genomic DNA No translation available.
AC006925 Genomic DNA No translation available.
AC015724 Genomic DNA No translation available.
CCDSiCCDS32686.1
RefSeqiNP_694960.2, NM_153228.2

3D structure databases

AlphaFoldDBiQ8N957
SMRiQ8N957
ModBaseiSearch...

Protein-protein interaction databases

STRINGi9606.ENSP00000321627

PTM databases

iPTMnetiQ8N957
PhosphoSitePlusiQ8N957

Genetic variation databases

BioMutaiANKFN1
DMDMi269849542

Proteomic databases

jPOSTiQ8N957
MassIVEiQ8N957
PaxDbiQ8N957
PeptideAtlasiQ8N957
PRIDEiQ8N957
ProteomicsDBi72490

Protocols and materials databases

Antibodypedia a portal for validated antibodies

More...Antibodypediai		18285, 17 antibodies from 7 providers

The DNASU plasmid repository

More...DNASUi		162282

Genome annotation databases

EnsembliENST00000318698.6; ENSP00000321627.2; ENSG00000153930.13
GeneIDi162282
KEGGihsa:162282
UCSCiuc002iun.1, human

Organism-specific databases

Comparative Toxicogenomics Database

More...CTDi		162282
DisGeNETi162282

GeneCards: human genes, protein and diseases

More...GeneCardsi		ANKFN1
HGNCiHGNC:26766, ANKFN1
HPAiENSG00000153930, Group enriched (brain, cervix, fallopian tube)
neXtProtiNX_Q8N957
OpenTargetsiENSG00000153930
PharmGKBiPA142672624
VEuPathDBiHostDB:ENSG00000153930

GenAtlas: human gene database

More...GenAtlasi		Search...

Phylogenomic databases

eggNOGiKOG4485, Eukaryota
GeneTreeiENSGT00940000159856
HOGENOMiCLU_010667_0_0_1
InParanoidiQ8N957
OMAiSINWNCC
OrthoDBi1305469at2759
PhylomeDBiQ8N957
TreeFamiTF314968

Enzyme and pathway databases

PathwayCommonsiQ8N957
SignaLinkiQ8N957

Miscellaneous databases

BioGRID ORCS database of CRISPR phenotype screens

More...BioGRID-ORCSi		162282, 11 hits in 1063 CRISPR screens

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...ChiTaRSi		ANKFN1, human

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...GenomeRNAii		162282
PharosiQ8N957, Tdark

Protein Ontology

More...PROi		PR:Q8N957
RNActiQ8N957, protein

Gene expression databases

BgeeiENSG00000153930, Expressed in buccal mucosa cell and 119 other tissues
ExpressionAtlasiQ8N957, baseline and differential
GenevisibleiQ8N957, HS

Family and domain databases

CDDicd00063, FN3, 1 hit
Gene3Di1.25.40.20, 1 hit
2.60.40.10, 1 hit
InterProiView protein in InterPro
IPR039269, ANKFN1
IPR002110, Ankyrin_rpt
IPR036770, Ankyrin_rpt-contain_sf
IPR003961, FN3_dom
IPR036116, FN3_sf
IPR013783, Ig-like_fold
PANTHERiPTHR21437, PTHR21437, 1 hit
PfamiView protein in Pfam
PF13637, Ank_4, 1 hit
PF00041, fn3, 1 hit
SMARTiView protein in SMART
SM00248, ANK, 2 hits
SM00060, FN3, 1 hit
SUPFAMiSSF48403, SSF48403, 1 hit
SSF49265, SSF49265, 1 hit
PROSITEiView protein in PROSITE
PS50297, ANK_REP_REGION, 1 hit
PS50088, ANK_REPEAT, 1 hit
PS50853, FN3, 1 hit

MobiDB: a database of protein disorder and mobility annotations

More...MobiDBi		Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiANKF1_HUMAN
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q8N957
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: July 25, 2006
Last sequence update: November 24, 2009
Last modified: May 25, 2022
This is version 132 of the entry and version 2 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. Human chromosome 17
    Human chromosome 17: entries, gene names and cross-references to MIM
  2. Human entries with genetic variants
    List of human entries with genetic variants
  3. Human variants curated from literature reports
    Index of human variants curated from literature reports
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