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Entry version 121 (17 Jun 2020)
Sequence version 1 (01 Oct 2002)
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Protein

PRELI domain-containing protein 2

Gene

PRELID2

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at transcript leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
PRELI domain-containing protein 2
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:PRELID2
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 5

Organism-specific databases

Eukaryotic Pathogen Database Resources

More...
EuPathDBi
HostDB:ENSG00000186314.11

Human Gene Nomenclature Database

More...
HGNCi
HGNC:28306 PRELID2

neXtProt; the human protein knowledge platform

More...
neXtProti
NX_Q8N945

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

DisGeNET

More...
DisGeNETi
153768

Open Targets

More...
OpenTargetsi
ENSG00000186314

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...
PharmGKBi
PA162400041

Miscellaneous databases

Pharos NIH Druggable Genome Knowledgebase

More...
Pharosi
Q8N945 Tdark

Polymorphism and mutation databases

BioMuta curated single-nucleotide variation and disease association database

More...
BioMutai
PRELID2

Domain mapping of disease mutations (DMDM)

More...
DMDMi
74729598

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00003077731 – 189PRELI domain-containing protein 2Add BLAST189

Proteomic databases

MassIVE - Mass Spectrometry Interactive Virtual Environment

More...
MassIVEi
Q8N945

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q8N945

PeptideAtlas

More...
PeptideAtlasi
Q8N945

PRoteomics IDEntifications database

More...
PRIDEi
Q8N945

ProteomicsDB: a multi-organism proteome resource

More...
ProteomicsDBi
34099
72486 [Q8N945-1]
72487 [Q8N945-2]

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
Q8N945

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
Q8N945

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSG00000186314 Expressed in intestine and 158 other tissues

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
Q8N945 baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
Q8N945 HS

Organism-specific databases

Human Protein Atlas

More...
HPAi
ENSG00000186314 Tissue enhanced (intestine)

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGRID)

More...
BioGRIDi
127516, 18 interactors

STRING: functional protein association networks

More...
STRINGi
9606.ENSP00000335675

Miscellaneous databases

RNAct, Protein-RNA interaction predictions for model organisms.

More...
RNActi
Q8N945 protein

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
Q8N945

Database of comparative protein structure models

More...
ModBasei
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini1 – 187PRELI/MSF1PROSITE-ProRule annotationAdd BLAST187

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
ENOG410IIHT Eukaryota
ENOG4111WVY LUCA

Ensembl GeneTree

More...
GeneTreei
ENSGT00950000182810

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
CLU_067902_6_0_1

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q8N945

Identification of Orthologs from Complete Genome Data

More...
OMAi
YLEEESW

Database of Orthologous Groups

More...
OrthoDBi
1449441at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q8N945

TreeFam database of animal gene trees

More...
TreeFami
TF337953

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR006797 PRELI/MSF1_dom
IPR037365 Slowmo/Ups

The PANTHER Classification System

More...
PANTHERi
PTHR11158 PTHR11158, 1 hit

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF04707 PRELI, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS50904 PRELI_MSF1, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequences (3+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry describes 3 <p>This subsection of the 'Sequence' section lists the alternative protein sequences (isoforms) that can be generated from the same gene by a single or by the combination of up to four biological events (alternative promoter usage, alternative splicing, alternative initiation and ribosomal frameshifting). Additionally, this section gives relevant information on each alternative protein isoform. This section is only present in reviewed entries, i.e. in UniProtKB/Swiss-Prot.<p><a href='/help/alternative_products' target='_top'>More...</a></p> isoformsi produced by alternative splicing. AlignAdd to basket

This entry has 3 described isoforms and 1 potential isoform that is computationally mapped.Show allAlign All

Isoform 1 (identifier: Q8N945-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the <div> <p><b>What is the canonical sequence?</b><p><a href='/help/canonical_and_isoforms' target='_top'>More...</a></p>canonicali sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide
        10         20         30         40         50
MGVSVDVHQV YKYPFEQVVA SFLRKYPNPM DKNVISVKIM EEKRDESTGV
60 70 80 90 100
IYRKRIAICQ NVVPEILRKS LSTLVILCWK KVSILKVPNI QLEEESWLNP
110 120 130 140 150
RERNMAIRSH CLTWTQYASM KEESVFRESM ENPNWTEFIQ RGRISITGVG
160 170 180
FLNCVLETFA STFLRQGAQK GIRIMEMLLK EQCGAPLAE
Length:189
Mass (Da):21,905
Last modified:October 1, 2002 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iAE39CE8FE26C7851
GO
Isoform 2 (identifier: Q8N945-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     1-29: Missing.
     70-81: Missing.

Show »
Length:148
Mass (Da):17,151
Checksum:iC360E57E8F6CCCD4
GO
Isoform 3 (identifier: Q8N945-3) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     69-80: Missing.

Show »
Length:177
Mass (Da):20,532
Checksum:iBF6077444FAEB749
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There is 1 potential isoform mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
D6RAB6D6RAB6_HUMAN
PRELI domain-containing protein 2
PRELID2
164Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

<p>This subsection of the 'Sequence' section reports difference(s) between the protein sequence shown in the UniProtKB entry and other available protein sequences derived from the same gene.<p><a href='/help/sequence_caution' target='_top'>More...</a></p>Sequence cautioni

The sequence BQ425760 differs from that shown. Reason: Frameshift.Curated

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section describes natural variant(s) of the protein sequence.<p><a href='/help/variant' target='_top'>More...</a></p>Natural variantiVAR_05391099N → S. Corresponds to variant dbSNP:rs9324996Ensembl.1

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section describes the sequence of naturally occurring alternative protein isoform(s). The changes in the amino acid sequence may be due to alternative splicing, alternative promoter usage, alternative initiation, or ribosomal frameshifting.<p><a href='/help/var_seq' target='_top'>More...</a></p>Alternative sequenceiVSP_0288241 – 29Missing in isoform 2. 1 PublicationAdd BLAST29
Alternative sequenceiVSP_04484169 – 80Missing in isoform 3. 1 PublicationAdd BLAST12
Alternative sequenceiVSP_02882570 – 81Missing in isoform 2. 1 PublicationAdd BLAST12

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AK095695 mRNA Translation: BAC04611.1
AC008631 Genomic DNA No translation available.
AC008700 Genomic DNA No translation available.
AC011355 Genomic DNA No translation available.
AC011359 Genomic DNA No translation available.
AC011411 Genomic DNA No translation available.
CH471062 Genomic DNA Translation: EAW61857.1
CH471062 Genomic DNA Translation: EAW61858.1
BC012033 mRNA Translation: AAH12033.1
BQ425760 mRNA No translation available.

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS34261.1 [Q8N945-3]
CCDS34262.1 [Q8N945-1]
CCDS43377.1 [Q8N945-2]

NCBI Reference Sequences

More...
RefSeqi
NP_612501.3, NM_138492.5 [Q8N945-2]
NP_892005.1, NM_182960.3 [Q8N945-1]
NP_995318.1, NM_205846.2 [Q8N945-3]
XP_016864618.1, XM_017009129.1 [Q8N945-1]
XP_016864619.1, XM_017009130.1 [Q8N945-1]
XP_016864620.1, XM_017009131.1 [Q8N945-1]

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENST00000334744; ENSP00000335675; ENSG00000186314 [Q8N945-1]
ENST00000394450; ENSP00000377965; ENSG00000186314 [Q8N945-2]
ENST00000505416; ENSP00000424730; ENSG00000186314 [Q8N945-3]

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
153768

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
hsa:153768

UCSC genome browser

More...
UCSCi
uc003lno.3 human [Q8N945-1]

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Coding sequence diversityi

Alternative splicing, Polymorphism

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK095695 mRNA Translation: BAC04611.1
AC008631 Genomic DNA No translation available.
AC008700 Genomic DNA No translation available.
AC011355 Genomic DNA No translation available.
AC011359 Genomic DNA No translation available.
AC011411 Genomic DNA No translation available.
CH471062 Genomic DNA Translation: EAW61857.1
CH471062 Genomic DNA Translation: EAW61858.1
BC012033 mRNA Translation: AAH12033.1
BQ425760 mRNA No translation available.
CCDSiCCDS34261.1 [Q8N945-3]
CCDS34262.1 [Q8N945-1]
CCDS43377.1 [Q8N945-2]
RefSeqiNP_612501.3, NM_138492.5 [Q8N945-2]
NP_892005.1, NM_182960.3 [Q8N945-1]
NP_995318.1, NM_205846.2 [Q8N945-3]
XP_016864618.1, XM_017009129.1 [Q8N945-1]
XP_016864619.1, XM_017009130.1 [Q8N945-1]
XP_016864620.1, XM_017009131.1 [Q8N945-1]

3D structure databases

SMRiQ8N945
ModBaseiSearch...

Protein-protein interaction databases

BioGRIDi127516, 18 interactors
STRINGi9606.ENSP00000335675

PTM databases

iPTMnetiQ8N945
PhosphoSitePlusiQ8N945

Polymorphism and mutation databases

BioMutaiPRELID2
DMDMi74729598

Proteomic databases

MassIVEiQ8N945
PaxDbiQ8N945
PeptideAtlasiQ8N945
PRIDEiQ8N945
ProteomicsDBi34099
72486 [Q8N945-1]
72487 [Q8N945-2]

Protocols and materials databases

Antibodypedia a portal for validated antibodies

More...
Antibodypediai
27490 78 antibodies

The DNASU plasmid repository

More...
DNASUi
153768

Genome annotation databases

EnsembliENST00000334744; ENSP00000335675; ENSG00000186314 [Q8N945-1]
ENST00000394450; ENSP00000377965; ENSG00000186314 [Q8N945-2]
ENST00000505416; ENSP00000424730; ENSG00000186314 [Q8N945-3]
GeneIDi153768
KEGGihsa:153768
UCSCiuc003lno.3 human [Q8N945-1]

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
153768
DisGeNETi153768
EuPathDBiHostDB:ENSG00000186314.11

GeneCards: human genes, protein and diseases

More...
GeneCardsi
PRELID2
HGNCiHGNC:28306 PRELID2
HPAiENSG00000186314 Tissue enhanced (intestine)
neXtProtiNX_Q8N945
OpenTargetsiENSG00000186314
PharmGKBiPA162400041

GenAtlas: human gene database

More...
GenAtlasi
Search...

Phylogenomic databases

eggNOGiENOG410IIHT Eukaryota
ENOG4111WVY LUCA
GeneTreeiENSGT00950000182810
HOGENOMiCLU_067902_6_0_1
InParanoidiQ8N945
OMAiYLEEESW
OrthoDBi1449441at2759
PhylomeDBiQ8N945
TreeFamiTF337953

Miscellaneous databases

BioGRID ORCS database of CRISPR phenotype screens

More...
BioGRID-ORCSi
153768 1 hit in 788 CRISPR screens

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...
ChiTaRSi
PRELID2 human

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...
GenomeRNAii
153768
PharosiQ8N945 Tdark

Protein Ontology

More...
PROi
PR:Q8N945
RNActiQ8N945 protein

Gene expression databases

BgeeiENSG00000186314 Expressed in intestine and 158 other tissues
ExpressionAtlasiQ8N945 baseline and differential
GenevisibleiQ8N945 HS

Family and domain databases

InterProiView protein in InterPro
IPR006797 PRELI/MSF1_dom
IPR037365 Slowmo/Ups
PANTHERiPTHR11158 PTHR11158, 1 hit
PfamiView protein in Pfam
PF04707 PRELI, 1 hit
PROSITEiView protein in PROSITE
PS50904 PRELI_MSF1, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiPRLD2_HUMAN
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q8N945
Secondary accession number(s): G5EA01, Q96EQ3
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: October 23, 2007
Last sequence update: October 1, 2002
Last modified: June 17, 2020
This is version 121 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. Human entries with polymorphisms or disease mutations
    List of human entries with polymorphisms or disease mutations
  2. Human polymorphisms and disease mutations
    Index of human polymorphisms and disease mutations
  3. Human chromosome 5
    Human chromosome 5: entries, gene names and cross-references to MIM
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