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Entry version 142 (16 Oct 2019)
Sequence version 2 (19 Jul 2004)
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Protein

Discoidin, CUB and LCCL domain-containing protein 1

Gene

DCBLD1

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:3 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Discoidin, CUB and LCCL domain-containing protein 1
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:DCBLD1
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 6

Organism-specific databases

Human Gene Nomenclature Database

More...
HGNCi
HGNC:21479 DCBLD1

neXtProt; the human protein knowledge platform

More...
neXtProti
NX_Q8N8Z6

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular_location_section">'Subcellular location'</a> section describes the subcellular compartment where each non-membrane region of a membrane-spanning protein is found.<p><a href='/help/topo_dom' target='_top'>More...</a></p>Topological domaini35 – 459ExtracellularSequence analysisAdd BLAST425
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular_location_section">'Subcellular location'</a> section describes the extent of a membrane-spanning region of the protein. It denotes the presence of both alpha-helical transmembrane regions and the membrane spanning regions of beta-barrel transmembrane proteins.<p><a href='/help/transmem' target='_top'>More...</a></p>Transmembranei460 – 480HelicalSequence analysisAdd BLAST21
Topological domaini481 – 715CytoplasmicSequence analysisAdd BLAST235

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Cellular componenti

Membrane

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

DisGeNET

More...
DisGeNETi
285761

Open Targets

More...
OpenTargetsi
ENSG00000164465

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...
PharmGKBi
PA134903108

Miscellaneous databases

Pharos NIH Druggable Genome Knowledgebase

More...
Pharosi
Q8N8Z6

Polymorphism and mutation databases

BioMuta curated single-nucleotide variation and disease association database

More...
BioMutai
DCBLD1

Domain mapping of disease mutations (DMDM)

More...
DMDMi
50400555

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section denotes the presence of an N-terminal signal peptide.<p><a href='/help/signal' target='_top'>More...</a></p>Signal peptidei1 – 34Sequence analysisAdd BLAST34
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_000002107635 – 715Discoidin, CUB and LCCL domain-containing protein 1Add BLAST681

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the PTM / Processing":/help/ptm_processing_section section describes the positions of cysteine residues participating in disulfide bonds.<p><a href='/help/disulfid' target='_top'>More...</a></p>Disulfide bondi41 ↔ 68By similarity
<p>This subsection of the <a href="http://www.uniprot.org/help/ptm_processing_section">PTM / Processing</a> section specifies the position and type of each covalently attached glycan group (mono-, di-, or polysaccharide).<p><a href='/help/carbohyd' target='_top'>More...</a></p>Glycosylationi64N-linked (GlcNAc...) asparagineSequence analysis1
Disulfide bondi94 ↔ 112By similarity
Glycosylationi124N-linked (GlcNAc...) asparagineSequence analysis1
Disulfide bondi158 ↔ 174By similarity
Disulfide bondi178 ↔ 200By similarity
Glycosylationi277N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi351N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi418N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi455N-linked (GlcNAc...) asparagineSequence analysis1
<p>This subsection of the ‘PTM / Processing’ section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei513PhosphoserineBy similarity1
Modified residuei614PhosphothreonineCombined sources1

Keywords - PTMi

Disulfide bond, Glycoprotein, Phosphoprotein

Proteomic databases

Encyclopedia of Proteome Dynamics

More...
EPDi
Q8N8Z6

jPOST - Japan Proteome Standard Repository/Database

More...
jPOSTi
Q8N8Z6

MassIVE - Mass Spectrometry Interactive Virtual Environment

More...
MassIVEi
Q8N8Z6

MaxQB - The MaxQuant DataBase

More...
MaxQBi
Q8N8Z6

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q8N8Z6

PeptideAtlas

More...
PeptideAtlasi
Q8N8Z6

PRoteomics IDEntifications database

More...
PRIDEi
Q8N8Z6

ProteomicsDB: a multi-organism proteome resource

More...
ProteomicsDBi
72477 [Q8N8Z6-1]
72478 [Q8N8Z6-2]

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
Q8N8Z6

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
Q8N8Z6

SwissPalm database of S-palmitoylation events

More...
SwissPalmi
Q8N8Z6

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSG00000164465 Expressed in 166 organ(s), highest expression level in visceral pleura

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
Q8N8Z6 baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
Q8N8Z6 HS

Organism-specific databases

Human Protein Atlas

More...
HPAi
HPA059667

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGrid)

More...
BioGridi
130203, 5 interactors

Protein interaction database and analysis system

More...
IntActi
Q8N8Z6, 4 interactors

Molecular INTeraction database

More...
MINTi
Q8N8Z6

STRING: functional protein association networks

More...
STRINGi
9606.ENSP00000296955

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family_and_domains_section">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini41 – 150CUBPROSITE-ProRule annotationAdd BLAST110
Domaini152 – 248LCCLPROSITE-ProRule annotationAdd BLAST97
Domaini248 – 412F5/8 type CPROSITE-ProRule annotationAdd BLAST165

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi482 – 486Poly-Lys5

Keywords - Domaini

Signal, Transmembrane, Transmembrane helix

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
ENOG410II5Z Eukaryota
ENOG4110JCT LUCA

Ensembl GeneTree

More...
GeneTreei
ENSGT00940000157334

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
HOG000000681

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q8N8Z6

Identification of Orthologs from Complete Genome Data

More...
OMAi
HKQREWL

Database of Orthologous Groups

More...
OrthoDBi
317808at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q8N8Z6

Family and domain databases

Conserved Domains Database

More...
CDDi
cd00041 CUB, 1 hit
cd00057 FA58C, 1 hit

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
2.170.130.20, 1 hit
2.60.120.260, 1 hit
2.60.120.290, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR000859 CUB_dom
IPR000421 FA58C
IPR008979 Galactose-bd-like_sf
IPR004043 LCCL
IPR036609 LCCL_sf
IPR035914 Sperma_CUB_dom_sf

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF00431 CUB, 1 hit
PF00754 F5_F8_type_C, 1 hit
PF03815 LCCL, 1 hit

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00042 CUB, 1 hit
SM00231 FA58C, 1 hit
SM00603 LCCL, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF49785 SSF49785, 1 hit
SSF49854 SSF49854, 1 hit
SSF69848 SSF69848, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS01180 CUB, 1 hit
PS01285 FA58C_1, 1 hit
PS50022 FA58C_3, 1 hit
PS50820 LCCL, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequences (2+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is in its mature form or if it represents the precursor.<p><a href='/help/sequence_processing' target='_top'>More...</a></p>Sequence processingi: The displayed sequence is further processed into a mature form.

This entry describes 2 <p>This subsection of the ‘Sequence’ section lists the alternative protein sequences (isoforms) that can be generated from the same gene by a single or by the combination of up to four biological events (alternative promoter usage, alternative splicing, alternative initiation and ribosomal frameshifting). Additionally, this section gives relevant information on each alternative protein isoform.<p><a href='/help/alternative_products' target='_top'>More...</a></p> isoformsi produced by alternative splicing. AlignAdd to basket

This entry has 2 described isoforms and 1 potential isoform that is computationally mapped.Show allAlign All

Isoform 1 (identifier: Q8N8Z6-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the <div> <p><b>What is the canonical sequence?</b><p><a href='/help/canonical_and_isoforms' target='_top'>More...</a></p>canonicali sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide
        10         20         30         40         50
MVPGARGGGA LARAAGRGLL ALLLAVSAPL RLQAEELGDG CGHLVTYQDS
60 70 80 90 100
GTMTSKNYPG TYPNHTVCEK TITVPKGKRL ILRLGDLDIE SQTCASDYLL
110 120 130 140 150
FTSSSDQYGP YCGSMTVPKE LLLNTSEVTV RFESGSHISG RGFLLTYASS
160 170 180 190 200
DHPDLITCLE RASHYLKTEY SKFCPAGCRD VAGDISGNMV DGYRDTSLLC
210 220 230 240 250
KAAIHAGIIA DELGGQISVL QRKGISRYEG ILANGVLSRD GSLSDKRFLF
260 270 280 290 300
TSNGCSRSLS FEPDGQIRAS SSWQSVNESG DQVHWSPGQA RLQDQGPSWA
310 320 330 340 350
SGDSSNNHKP REWLEIDLGE KKKITGIRTT GSTQSNFNFY VKSFVMNFKN
360 370 380 390 400
NNSKWKTYKG IVNNEEKVFQ GNSNFRDPVQ NNFIPPIVAR YVRVVPQTWH
410 420 430 440 450
QRIALKVELI GCQITQGNDS LVWRKTSQST SVSTKKEDET ITRPIPSEET
460 470 480 490 500
STGINITTVA IPLVLLVVLV FAGMGIFAAF RKKKKKGSPY GSAEAQKTDC
510 520 530 540 550
WKQIKYPFAR HQSAEFTISY DNEKEMTQKL DLITSDMADY QQPLMIGTGT
560 570 580 590 600
VTRKGSTFRP MDTDAEEAGV STDAGGHYDC PQRAGRHEYA LPLAPPEPEY
610 620 630 640 650
ATPIVERHVL RAHTFSAQSG YRVPGPQPGH KHSLSSGGFS PVAGVGAQDG
660 670 680 690 700
DYQRPHSAQP ADRGYDRPKA VSALATESGH PDSQKPPTHP GTSDSYSAPR
710
DCLTPLNQTA MTALL
Length:715
Mass (Da):77,920
Last modified:July 19, 2004 - v2
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iF8724D094F66EF2E
GO
Isoform 2 (identifier: Q8N8Z6-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     539-539: D → G
     540-715: Missing.

Show »
Length:539
Mass (Da):59,196
Checksum:i929D4B1AC1AAAA4C
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There is 1 potential isoform mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
H0Y4G4H0Y4G4_HUMAN
Discoidin, CUB and LCCL domain-cont...
DCBLD1
99Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

<p>This subsection of the ‘Sequence’ section reports difference(s) between the protein sequence shown in the UniProtKB entry and other available protein sequences derived from the same gene.<p><a href='/help/sequence_caution' target='_top'>More...</a></p>Sequence cautioni

The sequence BAC04663 differs from that shown. Reason: Frameshift.Curated
The sequence BAC05258 differs from that shown. Reason: Erroneous initiation. Truncated N-terminus.Curated

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti57N → D in BAC04663 (PubMed:14702039).Curated1
Sequence conflicti369F → L in BAC05258 (PubMed:14702039).Curated1

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section describes the sequence of naturally occurring alternative protein isoform(s). The changes in the amino acid sequence may be due to alternative splicing, alternative promoter usage, alternative initiation, or ribosomal frameshifting.<p><a href='/help/var_seq' target='_top'>More...</a></p>Alternative sequenceiVSP_040221539D → G in isoform 2. 1 Publication1
Alternative sequenceiVSP_040222540 – 715Missing in isoform 2. 1 PublicationAdd BLAST176

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AK098194 mRNA Translation: BAC05258.1 Different initiation.
AK095973 mRNA Translation: BAC04663.1 Frameshift.
AL132671 Genomic DNA No translation available.
Z85999 Genomic DNA No translation available.
BC035671 mRNA Translation: AAH35671.1

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS34522.1 [Q8N8Z6-2]

NCBI Reference Sequences

More...
RefSeqi
NP_775945.1, NM_173674.2 [Q8N8Z6-2]

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENST00000296955; ENSP00000296955; ENSG00000164465 [Q8N8Z6-2]
ENST00000338728; ENSP00000342422; ENSG00000164465 [Q8N8Z6-1]

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
285761

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
hsa:285761

UCSC genome browser

More...
UCSCi
uc003pxs.4 human [Q8N8Z6-1]

Keywords - Coding sequence diversityi

Alternative splicing

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK098194 mRNA Translation: BAC05258.1 Different initiation.
AK095973 mRNA Translation: BAC04663.1 Frameshift.
AL132671 Genomic DNA No translation available.
Z85999 Genomic DNA No translation available.
BC035671 mRNA Translation: AAH35671.1
CCDSiCCDS34522.1 [Q8N8Z6-2]
RefSeqiNP_775945.1, NM_173674.2 [Q8N8Z6-2]

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

Protein-protein interaction databases

BioGridi130203, 5 interactors
IntActiQ8N8Z6, 4 interactors
MINTiQ8N8Z6
STRINGi9606.ENSP00000296955

PTM databases

iPTMnetiQ8N8Z6
PhosphoSitePlusiQ8N8Z6
SwissPalmiQ8N8Z6

Polymorphism and mutation databases

BioMutaiDCBLD1
DMDMi50400555

Proteomic databases

EPDiQ8N8Z6
jPOSTiQ8N8Z6
MassIVEiQ8N8Z6
MaxQBiQ8N8Z6
PaxDbiQ8N8Z6
PeptideAtlasiQ8N8Z6
PRIDEiQ8N8Z6
ProteomicsDBi72477 [Q8N8Z6-1]
72478 [Q8N8Z6-2]

Genome annotation databases

EnsembliENST00000296955; ENSP00000296955; ENSG00000164465 [Q8N8Z6-2]
ENST00000338728; ENSP00000342422; ENSG00000164465 [Q8N8Z6-1]
GeneIDi285761
KEGGihsa:285761
UCSCiuc003pxs.4 human [Q8N8Z6-1]

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
285761
DisGeNETi285761

GeneCards: human genes, protein and diseases

More...
GeneCardsi
DCBLD1
HGNCiHGNC:21479 DCBLD1
HPAiHPA059667
neXtProtiNX_Q8N8Z6
OpenTargetsiENSG00000164465
PharmGKBiPA134903108

GenAtlas: human gene database

More...
GenAtlasi
Search...

Phylogenomic databases

eggNOGiENOG410II5Z Eukaryota
ENOG4110JCT LUCA
GeneTreeiENSGT00940000157334
HOGENOMiHOG000000681
InParanoidiQ8N8Z6
OMAiHKQREWL
OrthoDBi317808at2759
PhylomeDBiQ8N8Z6

Miscellaneous databases

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...
ChiTaRSi
DCBLD1 human

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...
GenomeRNAii
285761
PharosiQ8N8Z6

Protein Ontology

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PROi
PR:Q8N8Z6

Gene expression databases

BgeeiENSG00000164465 Expressed in 166 organ(s), highest expression level in visceral pleura
ExpressionAtlasiQ8N8Z6 baseline and differential
GenevisibleiQ8N8Z6 HS

Family and domain databases

CDDicd00041 CUB, 1 hit
cd00057 FA58C, 1 hit
Gene3Di2.170.130.20, 1 hit
2.60.120.260, 1 hit
2.60.120.290, 1 hit
InterProiView protein in InterPro
IPR000859 CUB_dom
IPR000421 FA58C
IPR008979 Galactose-bd-like_sf
IPR004043 LCCL
IPR036609 LCCL_sf
IPR035914 Sperma_CUB_dom_sf
PfamiView protein in Pfam
PF00431 CUB, 1 hit
PF00754 F5_F8_type_C, 1 hit
PF03815 LCCL, 1 hit
SMARTiView protein in SMART
SM00042 CUB, 1 hit
SM00231 FA58C, 1 hit
SM00603 LCCL, 1 hit
SUPFAMiSSF49785 SSF49785, 1 hit
SSF49854 SSF49854, 1 hit
SSF69848 SSF69848, 1 hit
PROSITEiView protein in PROSITE
PS01180 CUB, 1 hit
PS01285 FA58C_1, 1 hit
PS50022 FA58C_3, 1 hit
PS50820 LCCL, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

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ProtoNeti
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MobiDB: a database of protein disorder and mobility annotations

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MobiDBi
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<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiDCBD1_HUMAN
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q8N8Z6
Secondary accession number(s): Q5H992
, Q8IYK5, Q8N7L9, Q96NH2
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: July 19, 2004
Last sequence update: July 19, 2004
Last modified: October 16, 2019
This is version 142 of the entry and version 2 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Human chromosome 6
    Human chromosome 6: entries, gene names and cross-references to MIM
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