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Entry version 151 (07 Apr 2021)
Sequence version 2 (30 May 2003)
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Protein

Mitochondrial basic amino acids transporter

Gene

SLC25A29

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Transports arginine, lysine, homoarginine, methylarginine and, to a much lesser extent, ornithine and histidine (PubMed:24652292). Can restore ornithine transport in cells lacking the primary mitochondrial ornithine transporter SLC25A15 (PubMed:19287344). Does not transport carnitine nor acylcarnitines (PubMed:24652292). Functions by both counter-exchange and uniport mechanisms (PubMed:24652292).2 Publications

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Biological processAmino-acid transport, Transport

Enzyme and pathway databases

Pathway Commons web resource for biological pathway data

More...
PathwayCommonsi
Q8N8R3

Reactome - a knowledgebase of biological pathways and processes

More...
Reactomei
R-HSA-352230, Amino acid transport across the plasma membrane

Protein family/group databases

Transport Classification Database

More...
TCDBi
2.A.29.8.9, the mitochondrial carrier (mc) family

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Mitochondrial basic amino acids transporter
Alternative name(s):
Carnitine/acylcarnitine translocase-like
Short name:
CACT-like
Mitochondrial carnitine/acylcarnitine carrier protein CACL
Mitochondrial ornithine transporter 3
Solute carrier family 25 member 29
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:SLC25A29
Synonyms:C14orf69, ORNT3
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 14

Organism-specific databases

Human Gene Nomenclature Database

More...
HGNCi
HGNC:20116, SLC25A29

Online Mendelian Inheritance in Man (OMIM)

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MIMi
615064, gene

neXtProt; the human protein knowledge platform

More...
neXtProti
NX_Q8N8R3

Eukaryotic Pathogen, Vector and Host Database Resources

More...
VEuPathDBi
HostDB:ENSG00000197119.12

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular%5Flocation%5Fsection">'Subcellular location'</a> section describes the extent of a membrane-spanning region of the protein. It denotes the presence of both alpha-helical transmembrane regions and the membrane spanning regions of beta-barrel transmembrane proteins.<p><a href='/help/transmem' target='_top'>More...</a></p>Transmembranei2 – 22Helical; Name=1Sequence analysisAdd BLAST21
Transmembranei61 – 81Helical; Name=2Sequence analysisAdd BLAST21
Transmembranei96 – 116Helical; Name=3Sequence analysisAdd BLAST21
Transmembranei153 – 172Helical; Name=4Sequence analysisAdd BLAST20
Transmembranei187 – 207Helical; Name=5Sequence analysisAdd BLAST21
Transmembranei255 – 275Helical; Name=6Sequence analysisAdd BLAST21

Keywords - Cellular componenti

Membrane, Mitochondrion, Mitochondrion inner membrane

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

DisGeNET

More...
DisGeNETi
123096

Open Targets

More...
OpenTargetsi
ENSG00000197119

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...
PharmGKBi
PA134980581

Miscellaneous databases

Pharos NIH Druggable Genome Knowledgebase

More...
Pharosi
Q8N8R3, Tbio

Chemistry databases

Drug and drug target database

More...
DrugBanki
DB00583, Levocarnitine

Genetic variation databases

BioMuta curated single-nucleotide variation and disease association database

More...
BioMutai
SLC25A29

Domain mapping of disease mutations (DMDM)

More...
DMDMi
31340019

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00000906321 – 303Mitochondrial basic amino acids transporterAdd BLAST303

Proteomic databases

Encyclopedia of Proteome Dynamics

More...
EPDi
Q8N8R3

jPOST - Japan Proteome Standard Repository/Database

More...
jPOSTi
Q8N8R3

MassIVE - Mass Spectrometry Interactive Virtual Environment

More...
MassIVEi
Q8N8R3

MaxQB - The MaxQuant DataBase

More...
MaxQBi
Q8N8R3

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q8N8R3

PeptideAtlas

More...
PeptideAtlasi
Q8N8R3

PRoteomics IDEntifications database

More...
PRIDEi
Q8N8R3

ProteomicsDB: a multi-organism proteome resource

More...
ProteomicsDBi
580
72454 [Q8N8R3-1]

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
Q8N8R3

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
Q8N8R3

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSG00000197119, Expressed in left lobe of thyroid gland and 210 other tissues

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
Q8N8R3, baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
Q8N8R3, HS

Organism-specific databases

Human Protein Atlas

More...
HPAi
ENSG00000197119, Tissue enhanced (thyroid)

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGRID)

More...
BioGRIDi
125814, 4 interactors

STRING: functional protein association networks

More...
STRINGi
9606.ENSP00000352167

Miscellaneous databases

RNAct, Protein-RNA interaction predictions for model organisms.

More...
RNActi
Q8N8R3, protein

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
Q8N8R3

Database of comparative protein structure models

More...
ModBasei
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section indicates the positions and types of repeated sequence motifs or repeated domains within the protein.<p><a href='/help/repeat' target='_top'>More...</a></p>Repeati2 – 86Solcar 1Add BLAST85
Repeati90 – 178Solcar 2Add BLAST89
Repeati185 – 275Solcar 3Add BLAST91

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Keywords - Domaini

Repeat, Transmembrane, Transmembrane helix

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG0762, Eukaryota

Ensembl GeneTree

More...
GeneTreei
ENSGT00940000157766

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
CLU_015166_16_1_1

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q8N8R3

Identification of Orthologs from Complete Genome Data

More...
OMAi
FLMYMRS

Database of Orthologous Groups

More...
OrthoDBi
1072378at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q8N8R3

TreeFam database of animal gene trees

More...
TreeFami
TF351739

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
1.50.40.10, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR002067, Mit_carrier
IPR018108, Mitochondrial_sb/sol_carrier
IPR023395, Mt_carrier_dom_sf

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF00153, Mito_carr, 3 hits

Protein Motif fingerprint database; a protein domain database

More...
PRINTSi
PR00926, MITOCARRIER

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF103506, SSF103506, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS50920, SOLCAR, 3 hits

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequences (3+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry describes 3 <p>This subsection of the 'Sequence' section lists the alternative protein sequences (isoforms) that can be generated from the same gene by a single or by the combination of up to four biological events (alternative promoter usage, alternative splicing, alternative initiation and ribosomal frameshifting). Additionally, this section gives relevant information on each alternative protein isoform. This section is only present in reviewed entries, i.e. in UniProtKB/Swiss-Prot.<p><a href='/help/alternative_products' target='_top'>More...</a></p> isoformsi produced by alternative splicing. AlignAdd to basket

This entry has 3 described isoforms and 4 potential isoforms that are computationally mapped.Show allAlign All

Isoform 1 (identifier: Q8N8R3-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the <div> <p><b>What is the canonical sequence?</b><p><a href='/help/canonical_and_isoforms' target='_top'>More...</a></p>canonicali sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide
        10         20         30         40         50
MALDFLAGCA GGVAGVLVGH PFDTVKVRLQ VQSVEKPQYR GTLHCFKSII
60 70 80 90 100
KQESVLGLYK GLGSPLMGLT FINALVFGVQ GNTLRALGHD SPLNQFLAGA
110 120 130 140 150
AAGAIQCVIC CPMELAKTRL QLQDAGPART YKGSLDCLAQ IYGHEGLRGV
160 170 180 190 200
NRGMVSTLLR ETPSFGVYFL TYDALTRALG CEPGDRLLVP KLLLAGGTSG
210 220 230 240 250
IVSWLSTYPV DVVKSRLQAD GLRGAPRYRG ILDCVHQSYR AEGWRVFTRG
260 270 280 290 300
LASTLLRAFP VNAATFATVT VVLTYARGEE AGPEGEAVPA APAGPALAQP

SSL
Length:303
Mass (Da):32,062
Last modified:May 30, 2003 - v2
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i34C2D596781EE58A
GO
Isoform 2 (identifier: Q8N8R3-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     13-145: VAGVLVGHPF...DCLAQIYGHE → TASGPERGEA...QPGHGVHVAA
     146-303: Missing.

Note: May be produced at very low levels due to a premature stop codon in the mRNA, leading to nonsense-mediated mRNA decay.Curated
Show »
Length:145
Mass (Da):14,504
Checksum:i351A973379EAF6EA
GO
Isoform 3 (identifier: Q8N8R3-3) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     1-66: Missing.

Show »
Length:237
Mass (Da):25,051
Checksum:iAB0E43F7F7052DD5
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 4 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
G3V5F4G3V5F4_HUMAN
Mitochondrial basic amino acids tra...
SLC25A29
129Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
G3V4H8G3V4H8_HUMAN
Mitochondrial basic amino acids tra...
SLC25A29
122Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
G3V441G3V441_HUMAN
Mitochondrial basic amino acids tra...
SLC25A29
35Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
G3V477G3V477_HUMAN
Mitochondrial basic amino acids tra...
SLC25A29
138Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

<p>This subsection of the 'Sequence' section reports difference(s) between the protein sequence shown in the UniProtKB entry and other available protein sequences derived from the same gene.<p><a href='/help/sequence_caution' target='_top'>More...</a></p>Sequence cautioni

The sequence CAD62317 differs from that shown. Reason: Erroneous initiation. Extended N-terminus.Curated

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section describes the sequence of naturally occurring alternative protein isoform(s). The changes in the amino acid sequence may be due to alternative splicing, alternative promoter usage, alternative initiation, or ribosomal frameshifting.<p><a href='/help/var_seq' target='_top'>More...</a></p>Alternative sequenceiVSP_0553351 – 66Missing in isoform 3. 2 PublicationsAdd BLAST66
Alternative sequenceiVSP_04628613 – 145VAGVL…IYGHE → TASGPERGEASVPRDVALLQ VHHQARERAGPVQGPGLAAH GAHLHQRAGVRGAGQHPPGP GPRLAPQPVPGRCGGGRHPV RHLLPHGAGQDAAAAAGRGP SAHLQGLAGLPRADLRARGS AWRQPGHGVHVAA in isoform 2. 1 PublicationAdd BLAST133
Alternative sequenceiVSP_046287146 – 303Missing in isoform 2. 1 PublicationAdd BLAST158

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
BX247983 mRNA Translation: CAD62317.1 Different initiation.
AK095532 mRNA Translation: BAG53079.1
AK096294 mRNA Translation: BAC04751.1
AK123821 mRNA Translation: BAG53964.1
AK172788 mRNA Translation: BAD18767.1
AK289627 mRNA Translation: BAF82316.1
AL157871 Genomic DNA No translation available.
CH471061 Genomic DNA Translation: EAW81692.1
CH471061 Genomic DNA Translation: EAW81695.1
BC132964 mRNA Translation: AAI32965.1
BC132966 mRNA Translation: AAI32967.1

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS32156.1 [Q8N8R3-1]

NCBI Reference Sequences

More...
RefSeqi
NP_001034444.1, NM_001039355.2 [Q8N8R3-1]
NP_001278742.1, NM_001291813.1 [Q8N8R3-3]
NP_001278743.1, NM_001291814.1 [Q8N8R3-3]
NP_689546.1, NM_152333.3 [Q8N8R3-3]
XP_011534748.1, XM_011536446.1
XP_011534749.1, XM_011536447.1 [Q8N8R3-3]
XP_011534750.1, XM_011536448.1 [Q8N8R3-3]
XP_016876469.1, XM_017020980.1
XP_016876470.1, XM_017020981.1
XP_016876471.1, XM_017020982.1
XP_016876472.1, XM_017020983.1
XP_016876473.1, XM_017020984.1
XP_016876474.1, XM_017020985.1
XP_016876475.1, XM_017020986.1
XP_016876476.1, XM_017020987.1

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENST00000359232; ENSP00000352167; ENSG00000197119 [Q8N8R3-1]
ENST00000392908; ENSP00000376640; ENSG00000197119 [Q8N8R3-2]
ENST00000554912; ENSP00000450913; ENSG00000197119 [Q8N8R3-3]
ENST00000555927; ENSP00000452078; ENSG00000197119 [Q8N8R3-3]
ENST00000556505; ENSP00000452446; ENSG00000197119 [Q8N8R3-3]

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
123096

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
hsa:123096

UCSC genome browser

More...
UCSCi
uc001yha.4, human [Q8N8R3-1]

Keywords - Coding sequence diversityi

Alternative splicing

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BX247983 mRNA Translation: CAD62317.1 Different initiation.
AK095532 mRNA Translation: BAG53079.1
AK096294 mRNA Translation: BAC04751.1
AK123821 mRNA Translation: BAG53964.1
AK172788 mRNA Translation: BAD18767.1
AK289627 mRNA Translation: BAF82316.1
AL157871 Genomic DNA No translation available.
CH471061 Genomic DNA Translation: EAW81692.1
CH471061 Genomic DNA Translation: EAW81695.1
BC132964 mRNA Translation: AAI32965.1
BC132966 mRNA Translation: AAI32967.1
CCDSiCCDS32156.1 [Q8N8R3-1]
RefSeqiNP_001034444.1, NM_001039355.2 [Q8N8R3-1]
NP_001278742.1, NM_001291813.1 [Q8N8R3-3]
NP_001278743.1, NM_001291814.1 [Q8N8R3-3]
NP_689546.1, NM_152333.3 [Q8N8R3-3]
XP_011534748.1, XM_011536446.1
XP_011534749.1, XM_011536447.1 [Q8N8R3-3]
XP_011534750.1, XM_011536448.1 [Q8N8R3-3]
XP_016876469.1, XM_017020980.1
XP_016876470.1, XM_017020981.1
XP_016876471.1, XM_017020982.1
XP_016876472.1, XM_017020983.1
XP_016876473.1, XM_017020984.1
XP_016876474.1, XM_017020985.1
XP_016876475.1, XM_017020986.1
XP_016876476.1, XM_017020987.1

3D structure databases

SMRiQ8N8R3
ModBaseiSearch...

Protein-protein interaction databases

BioGRIDi125814, 4 interactors
STRINGi9606.ENSP00000352167

Chemistry databases

DrugBankiDB00583, Levocarnitine

Protein family/group databases

TCDBi2.A.29.8.9, the mitochondrial carrier (mc) family

PTM databases

iPTMnetiQ8N8R3
PhosphoSitePlusiQ8N8R3

Genetic variation databases

BioMutaiSLC25A29
DMDMi31340019

Proteomic databases

EPDiQ8N8R3
jPOSTiQ8N8R3
MassIVEiQ8N8R3
MaxQBiQ8N8R3
PaxDbiQ8N8R3
PeptideAtlasiQ8N8R3
PRIDEiQ8N8R3
ProteomicsDBi580
72454 [Q8N8R3-1]

Protocols and materials databases

Antibodypedia a portal for validated antibodies

More...
Antibodypediai
14405, 36 antibodies

Genome annotation databases

EnsembliENST00000359232; ENSP00000352167; ENSG00000197119 [Q8N8R3-1]
ENST00000392908; ENSP00000376640; ENSG00000197119 [Q8N8R3-2]
ENST00000554912; ENSP00000450913; ENSG00000197119 [Q8N8R3-3]
ENST00000555927; ENSP00000452078; ENSG00000197119 [Q8N8R3-3]
ENST00000556505; ENSP00000452446; ENSG00000197119 [Q8N8R3-3]
GeneIDi123096
KEGGihsa:123096
UCSCiuc001yha.4, human [Q8N8R3-1]

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
123096
DisGeNETi123096

GeneCards: human genes, protein and diseases

More...
GeneCardsi
SLC25A29
HGNCiHGNC:20116, SLC25A29
HPAiENSG00000197119, Tissue enhanced (thyroid)
MIMi615064, gene
neXtProtiNX_Q8N8R3
OpenTargetsiENSG00000197119
PharmGKBiPA134980581
VEuPathDBiHostDB:ENSG00000197119.12

GenAtlas: human gene database

More...
GenAtlasi
Search...

Phylogenomic databases

eggNOGiKOG0762, Eukaryota
GeneTreeiENSGT00940000157766
HOGENOMiCLU_015166_16_1_1
InParanoidiQ8N8R3
OMAiFLMYMRS
OrthoDBi1072378at2759
PhylomeDBiQ8N8R3
TreeFamiTF351739

Enzyme and pathway databases

PathwayCommonsiQ8N8R3
ReactomeiR-HSA-352230, Amino acid transport across the plasma membrane

Miscellaneous databases

BioGRID ORCS database of CRISPR phenotype screens

More...
BioGRID-ORCSi
123096, 6 hits in 992 CRISPR screens

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...
ChiTaRSi
SLC25A29, human

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...
GenomeRNAii
123096
PharosiQ8N8R3, Tbio

Protein Ontology

More...
PROi
PR:Q8N8R3
RNActiQ8N8R3, protein

The Stanford Online Universal Resource for Clones and ESTs

More...
SOURCEi
Search...

Gene expression databases

BgeeiENSG00000197119, Expressed in left lobe of thyroid gland and 210 other tissues
ExpressionAtlasiQ8N8R3, baseline and differential
GenevisibleiQ8N8R3, HS

Family and domain databases

Gene3Di1.50.40.10, 1 hit
InterProiView protein in InterPro
IPR002067, Mit_carrier
IPR018108, Mitochondrial_sb/sol_carrier
IPR023395, Mt_carrier_dom_sf
PfamiView protein in Pfam
PF00153, Mito_carr, 3 hits
PRINTSiPR00926, MITOCARRIER
SUPFAMiSSF103506, SSF103506, 1 hit
PROSITEiView protein in PROSITE
PS50920, SOLCAR, 3 hits

ProtoNet; Automatic hierarchical classification of proteins

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ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiMCATL_HUMAN
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q8N8R3
Secondary accession number(s): A3KMR5, Q541V0
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: May 30, 2003
Last sequence update: May 30, 2003
Last modified: April 7, 2021
This is version 151 of the entry and version 2 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. Human chromosome 14
    Human chromosome 14: entries, gene names and cross-references to MIM
  2. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
  3. SIMILARITY comments
    Index of protein domains and families
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