UniProtKB - Q8N8L6 (ARL10_HUMAN)
Protein
ADP-ribosylation factor-like protein 10
Gene
ARL10
Organism
Homo sapiens (Human)
Status
Functioni
Regions
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Nucleotide bindingi | 84 – 91 | GTPBy similarity | 8 | |
Nucleotide bindingi | 128 – 132 | GTPBy similarity | 5 | |
Nucleotide bindingi | 185 – 188 | GTPBy similarity | 4 |
GO - Molecular functioni
- GTP binding Source: UniProtKB-KW
Keywordsi
Ligand | GTP-binding, Nucleotide-binding |
Enzyme and pathway databases
PathwayCommonsi | Q8N8L6 |
Names & Taxonomyi
Protein namesi | Recommended name: ADP-ribosylation factor-like protein 10 |
Gene namesi | Name:ARL10 Synonyms:ARL10A |
Organismi | Homo sapiens (Human) |
Taxonomic identifieri | 9606 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo |
Proteomesi |
|
Organism-specific databases
EuPathDBi | HostDB:ENSG00000175414.6 |
HGNCi | HGNC:22042, ARL10 |
neXtProti | NX_Q8N8L6 |
Pathology & Biotechi
Organism-specific databases
OpenTargetsi | ENSG00000175414 |
PharmGKBi | PA134871031 |
Miscellaneous databases
Pharosi | Q8N8L6, Tdark |
Polymorphism and mutation databases
BioMutai | ARL10 |
DMDMi | 74751109 |
PTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
ChainiPRO_0000207476 | 1 – 244 | ADP-ribosylation factor-like protein 10Add BLAST | 244 |
Proteomic databases
EPDi | Q8N8L6 |
jPOSTi | Q8N8L6 |
MassIVEi | Q8N8L6 |
PaxDbi | Q8N8L6 |
PeptideAtlasi | Q8N8L6 |
PRIDEi | Q8N8L6 |
ProteomicsDBi | 72435 |
PTM databases
iPTMneti | Q8N8L6 |
PhosphoSitePlusi | Q8N8L6 |
Expressioni
Gene expression databases
Bgeei | ENSG00000175414, Expressed in forebrain and 204 other tissues |
ExpressionAtlasi | Q8N8L6, baseline and differential |
Genevisiblei | Q8N8L6, HS |
Organism-specific databases
HPAi | ENSG00000175414, Low tissue specificity |
Interactioni
Protein-protein interaction databases
BioGRIDi | 130153, 31 interactors |
IntActi | Q8N8L6, 24 interactors |
STRINGi | 9606.ENSP00000308496 |
Miscellaneous databases
RNActi | Q8N8L6, protein |
Family & Domainsi
Sequence similaritiesi
Phylogenomic databases
eggNOGi | KOG0072, Eukaryota |
GeneTreei | ENSGT00940000160017 |
HOGENOMi | CLU_040729_11_0_1 |
InParanoidi | Q8N8L6 |
OMAi | TVHIWRL |
OrthoDBi | 1410051at2759 |
PhylomeDBi | Q8N8L6 |
TreeFami | TF105469 |
Family and domain databases
InterProi | View protein in InterPro IPR042951, ARL10 IPR027417, P-loop_NTPase IPR006689, Small_GTPase_ARF/SAR |
PANTHERi | PTHR47575, PTHR47575, 1 hit |
Pfami | View protein in Pfam PF00025, Arf, 1 hit |
PRINTSi | PR00328, SAR1GTPBP |
SUPFAMi | SSF52540, SSF52540, 1 hit |
PROSITEi | View protein in PROSITE PS51417, ARF, 1 hit |
(1+)i Sequence
Sequence statusi: Complete.
This entry has 1 described isoform and 2 potential isoforms that are computationally mapped.Show allAlign All
Q8N8L6-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MAPRPLGPLV LALGGAAAVL GSVLFILWKT YFGRGRERRW DRGEAWWGAE
60 70 80 90 100
AARLPEWDEW DPEDEEDEEP ALEELEQREV LVLGLDGAGK STFLRVLSGK
110 120 130 140 150
PPLEGHIPTW GFNSVRLPTK DFEVDLLEIG GSQNLRFYWK EFVSEVDVLV
160 170 180 190 200
FVVDSADRLR LPWARQELHK LLDKDPDLPV VVVANKQDLS EAMSMGELQR
210 220 230 240
ELGLQAIDNQ REVFLLAASI APAGPTFEEP GTVHIWKLLL ELLS
Computationally mapped potential isoform sequencesi
There are 2 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basketH0Y8L6 | H0Y8L6_HUMAN | ADP-ribosylation factor-like protei... | ARL10 | 48 | Annotation score: | ||
H0Y9R6 | H0Y9R6_HUMAN | ADP-ribosylation factor-like protei... | ARL10 | 79 | Annotation score: |
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AK096568 mRNA Translation: BAC04820.1 BK001673 mRNA Translation: DAA02136.1 |
CCDSi | CCDS4400.1 |
RefSeqi | NP_775935.1, NM_173664.5 |
Genome annotation databases
Ensembli | ENST00000310389; ENSP00000308496; ENSG00000175414 |
GeneIDi | 285598 |
KEGGi | hsa:285598 |
UCSCi | uc003mec.2, human |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AK096568 mRNA Translation: BAC04820.1 BK001673 mRNA Translation: DAA02136.1 |
CCDSi | CCDS4400.1 |
RefSeqi | NP_775935.1, NM_173664.5 |
3D structure databases
SMRi | Q8N8L6 |
ModBasei | Search... |
Protein-protein interaction databases
BioGRIDi | 130153, 31 interactors |
IntActi | Q8N8L6, 24 interactors |
STRINGi | 9606.ENSP00000308496 |
PTM databases
iPTMneti | Q8N8L6 |
PhosphoSitePlusi | Q8N8L6 |
Polymorphism and mutation databases
BioMutai | ARL10 |
DMDMi | 74751109 |
Proteomic databases
EPDi | Q8N8L6 |
jPOSTi | Q8N8L6 |
MassIVEi | Q8N8L6 |
PaxDbi | Q8N8L6 |
PeptideAtlasi | Q8N8L6 |
PRIDEi | Q8N8L6 |
ProteomicsDBi | 72435 |
Protocols and materials databases
Antibodypediai | 29070, 76 antibodies |
Genome annotation databases
Ensembli | ENST00000310389; ENSP00000308496; ENSG00000175414 |
GeneIDi | 285598 |
KEGGi | hsa:285598 |
UCSCi | uc003mec.2, human |
Organism-specific databases
CTDi | 285598 |
EuPathDBi | HostDB:ENSG00000175414.6 |
GeneCardsi | ARL10 |
HGNCi | HGNC:22042, ARL10 |
HPAi | ENSG00000175414, Low tissue specificity |
neXtProti | NX_Q8N8L6 |
OpenTargetsi | ENSG00000175414 |
PharmGKBi | PA134871031 |
GenAtlasi | Search... |
Phylogenomic databases
eggNOGi | KOG0072, Eukaryota |
GeneTreei | ENSGT00940000160017 |
HOGENOMi | CLU_040729_11_0_1 |
InParanoidi | Q8N8L6 |
OMAi | TVHIWRL |
OrthoDBi | 1410051at2759 |
PhylomeDBi | Q8N8L6 |
TreeFami | TF105469 |
Enzyme and pathway databases
PathwayCommonsi | Q8N8L6 |
Miscellaneous databases
BioGRID-ORCSi | 285598, 18 hits in 838 CRISPR screens |
ChiTaRSi | ARL10, human |
GenomeRNAii | 285598 |
Pharosi | Q8N8L6, Tdark |
PROi | PR:Q8N8L6 |
RNActi | Q8N8L6, protein |
Gene expression databases
Bgeei | ENSG00000175414, Expressed in forebrain and 204 other tissues |
ExpressionAtlasi | Q8N8L6, baseline and differential |
Genevisiblei | Q8N8L6, HS |
Family and domain databases
InterProi | View protein in InterPro IPR042951, ARL10 IPR027417, P-loop_NTPase IPR006689, Small_GTPase_ARF/SAR |
PANTHERi | PTHR47575, PTHR47575, 1 hit |
Pfami | View protein in Pfam PF00025, Arf, 1 hit |
PRINTSi | PR00328, SAR1GTPBP |
SUPFAMi | SSF52540, SSF52540, 1 hit |
PROSITEi | View protein in PROSITE PS51417, ARF, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | ARL10_HUMAN | |
Accessioni | Q8N8L6Primary (citable) accession number: Q8N8L6 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | November 22, 2005 |
Last sequence update: | October 1, 2002 | |
Last modified: | December 2, 2020 | |
This is version 142 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Chordata Protein Annotation Program | |
Disclaimer | Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. |
Miscellaneousi
Keywords - Technical termi
Reference proteomeDocuments
- Human chromosome 5
Human chromosome 5: entries, gene names and cross-references to MIM - SIMILARITY comments
Index of protein domains and families