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Entry version 120 (02 Jun 2021)
Sequence version 2 (20 May 2008)
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Protein

Protein YIPF7

Gene

YIPF7

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:4 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Caution

It is uncertain whether Met-1 or Met-25 is the initiator.Curated

Enzyme and pathway databases

Pathway Commons web resource for biological pathway data

More...
PathwayCommonsi
Q8N8F6

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Protein YIPF7
Alternative name(s):
Five-pass transmembrane protein localizing in the Golgi apparatus and the endoplasmic reticulum 9
YIP1 family member 7
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:YIPF7
Synonyms:FINGER9, YIP1B
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 4

Organism-specific databases

Human Gene Nomenclature Database

More...
HGNCi
HGNC:26825, YIPF7

neXtProt; the human protein knowledge platform

More...
neXtProti
NX_Q8N8F6

Eukaryotic Pathogen, Vector and Host Database Resources

More...
VEuPathDBi
HostDB:ENSG00000177752.14

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular%5Flocation%5Fsection">'Subcellular location'</a> section describes the subcellular compartment where each non-membrane region of a membrane-spanning protein is found.<p><a href='/help/topo_dom' target='_top'>More...</a></p>Topological domaini1 – 149Cytoplasmic1 PublicationAdd BLAST149
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular%5Flocation%5Fsection">'Subcellular location'</a> section describes the extent of a membrane-spanning region of the protein. It denotes the presence of both alpha-helical transmembrane regions and the membrane spanning regions of beta-barrel transmembrane proteins.<p><a href='/help/transmem' target='_top'>More...</a></p>Transmembranei150 – 170HelicalSequence analysisAdd BLAST21
Topological domaini171ExtracellularCurated1
Transmembranei172 – 192HelicalSequence analysisAdd BLAST21
Topological domaini193 – 196CytoplasmicCurated4
Transmembranei197 – 217HelicalSequence analysisAdd BLAST21
Topological domaini218 – 220ExtracellularCurated3
Transmembranei221 – 241HelicalSequence analysisAdd BLAST21
Topological domaini242 – 259CytoplasmicCuratedAdd BLAST18
Transmembranei260 – 280HelicalSequence analysisAdd BLAST21

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Cellular componenti

Endoplasmic reticulum, Golgi apparatus, Membrane

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

DisGeNET

More...
DisGeNETi
285525

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...
PharmGKBi
PA142670550

Miscellaneous databases

Pharos NIH Druggable Genome Knowledgebase

More...
Pharosi
Q8N8F6, Tdark

Genetic variation databases

BioMuta curated single-nucleotide variation and disease association database

More...
BioMutai
YIPF7

Domain mapping of disease mutations (DMDM)

More...
DMDMi
189030344

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00003330071 – 280Protein YIPF7Add BLAST280

Proteomic databases

MassIVE - Mass Spectrometry Interactive Virtual Environment

More...
MassIVEi
Q8N8F6

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q8N8F6

PeptideAtlas

More...
PeptideAtlasi
Q8N8F6

PRoteomics IDEntifications database

More...
PRIDEi
Q8N8F6

ProteomicsDB: a multi-organism proteome resource

More...
ProteomicsDBi
72414 [Q8N8F6-1]
72415 [Q8N8F6-2]
72416 [Q8N8F6-3]
72417 [Q8N8F6-4]

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
Q8N8F6

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
Q8N8F6

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSG00000177752, Expressed in quadriceps femoris and 98 other tissues

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
Q8N8F6, baseline and differential

Organism-specific databases

Human Protein Atlas

More...
HPAi
ENSG00000177752, Group enriched (skeletal muscle, tongue)

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

STRING: functional protein association networks

More...
STRINGi
9606.ENSP00000332772

Miscellaneous databases

RNAct, Protein-RNA interaction predictions for model organisms.

More...
RNActi
Q8N8F6, protein

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni43 – 72DisorderedSequence analysisAdd BLAST30

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the YIP1 family.Curated

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG3103, Eukaryota

Ensembl GeneTree

More...
GeneTreei
ENSGT00940000153168

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q8N8F6

Identification of Orthologs from Complete Genome Data

More...
OMAi
MLMSSGY

Database of Orthologous Groups

More...
OrthoDBi
1457080at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q8N8F6

TreeFam database of animal gene trees

More...
TreeFami
TF313100

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR006977, Yip1

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF04893, Yip1, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequences (4+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry describes 4 <p>This subsection of the 'Sequence' section lists the alternative protein sequences (isoforms) that can be generated from the same gene by a single or by the combination of up to four biological events (alternative promoter usage, alternative splicing, alternative initiation and ribosomal frameshifting). Additionally, this section gives relevant information on each alternative protein isoform.<p><a href='/help/alternative_products' target='_top'>More...</a></p> isoformsi produced by alternative splicing. AlignAdd to basket

This entry has 4 described isoforms and 2 potential isoforms that are computationally mapped.Show allAlign All

Isoform 1 (identifier: Q8N8F6-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the <div> <p><b>What is the canonical sequence?</b><p><a href='/help/canonical_and_isoforms' target='_top'>More...</a></p>canonicali sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide
        10         20         30         40         50
MDLLKISHTK LHLLEDLSIK NKQRMSNLAQ FDSDFYQSNF TIDNQEQSGN
60 70 80 90 100
DSNAYGNLYG SRKQQAGEQP QPASFVPSEM LMSSGYAGQF FQPASNSDYY
110 120 130 140 150
SQSPYIDSFD EEPPLLEELG IHFDHIWQKT LTVLNPMKPV DGSIMNETDL
160 170 180 190 200
TGPILFCVAL GATLLLAGKV QFGYVYGMSA IGCLVIHALL NLMSSSGVSY
210 220 230 240 250
GCVASVLGYC LLPMVILSGC AMFFSLQGIF GIMSSLVIIG WCSLSASKIF
260 270 280
IAALHMEGQQ LLVAYPCAIL YGLFALLTIF
Length:280
Mass (Da):30,632
Last modified:May 20, 2008 - v2
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iAF30804CB8B3FB36
GO
Isoform 2 (identifier: Q8N8F6-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     167-280: AGKVQFGYVY...YGLFALLTIF → VMCHRKHQIL...YIVNFLSERE

Show »
Length:208
Mass (Da):23,451
Checksum:i32B2284DDA9B38AB
GO
Isoform 3 (identifier: Q8N8F6-3) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     64-68: QQAGE → TWNPF
     69-280: Missing.

Show »
Length:68
Mass (Da):7,930
Checksum:i0F596C0EFAE09A46
GO
Isoform 4 (identifier: Q8N8F6-4) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     118-132: ELGIHFDHIWQKTLT → DKNLESILITYGKKL
     133-280: Missing.

Show »
Length:132
Mass (Da):14,977
Checksum:iA49AC6311303B48F
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 2 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
J3KR00J3KR00_HUMAN
Protein YIPF
YIPF7
256Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
V9GZ30V9GZ30_HUMAN
Protein YIPF7
YIPF7
39Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti50N → D in BAC04887 (PubMed:14702039).Curated1
Sequence conflicti138K → E in BAC04887 (PubMed:14702039).Curated1

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section describes natural variant(s) of the protein sequence.<p><a href='/help/variant' target='_top'>More...</a></p>Natural variantiVAR_04303654A → T1 PublicationCorresponds to variant dbSNP:rs2348353Ensembl.1

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section describes the sequence of naturally occurring alternative protein isoform(s). The changes in the amino acid sequence may be due to alternative splicing, alternative promoter usage, alternative initiation, or ribosomal frameshifting.<p><a href='/help/var_seq' target='_top'>More...</a></p>Alternative sequenceiVSP_03343164 – 68QQAGE → TWNPF in isoform 3. 1 Publication5
Alternative sequenceiVSP_03343269 – 280Missing in isoform 3. 1 PublicationAdd BLAST212
Alternative sequenceiVSP_033433118 – 132ELGIH…QKTLT → DKNLESILITYGKKL in isoform 4. 1 PublicationAdd BLAST15
Alternative sequenceiVSP_033434133 – 280Missing in isoform 4. 1 PublicationAdd BLAST148
Alternative sequenceiVSP_033435167 – 280AGKVQ…LLTIF → VMCHRKHQILMLVLSSAGFE AICINIRETVSPYIVNFLSE RE in isoform 2. 1 PublicationAdd BLAST114

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AK096895 mRNA Translation: BAC04887.1
AC093852 Genomic DNA No translation available.
AC096586 Genomic DNA No translation available.
AC108478 Genomic DNA No translation available.
BC103995 mRNA Translation: AAI03996.1
BC103996 mRNA Translation: AAI03997.1

NCBI Reference Sequences

More...
RefSeqi
NP_872398.2, NM_182592.2 [Q8N8F6-1]

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENST00000332990; ENSP00000332772; ENSG00000177752 [Q8N8F6-1]

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
285525

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
hsa:285525

UCSC genome browser

More...
UCSCi
uc062wht.1, human [Q8N8F6-1]

Keywords - Coding sequence diversityi

Alternative splicing

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK096895 mRNA Translation: BAC04887.1
AC093852 Genomic DNA No translation available.
AC096586 Genomic DNA No translation available.
AC108478 Genomic DNA No translation available.
BC103995 mRNA Translation: AAI03996.1
BC103996 mRNA Translation: AAI03997.1
RefSeqiNP_872398.2, NM_182592.2 [Q8N8F6-1]

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

Protein-protein interaction databases

STRINGi9606.ENSP00000332772

PTM databases

iPTMnetiQ8N8F6
PhosphoSitePlusiQ8N8F6

Genetic variation databases

BioMutaiYIPF7
DMDMi189030344

Proteomic databases

MassIVEiQ8N8F6
PaxDbiQ8N8F6
PeptideAtlasiQ8N8F6
PRIDEiQ8N8F6
ProteomicsDBi72414 [Q8N8F6-1]
72415 [Q8N8F6-2]
72416 [Q8N8F6-3]
72417 [Q8N8F6-4]

Protocols and materials databases

Antibodypedia a portal for validated antibodies

More...
Antibodypediai
23722, 28 antibodies

The DNASU plasmid repository

More...
DNASUi
285525

Genome annotation databases

EnsembliENST00000332990; ENSP00000332772; ENSG00000177752 [Q8N8F6-1]
GeneIDi285525
KEGGihsa:285525
UCSCiuc062wht.1, human [Q8N8F6-1]

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
285525
DisGeNETi285525

GeneCards: human genes, protein and diseases

More...
GeneCardsi
YIPF7
HGNCiHGNC:26825, YIPF7
HPAiENSG00000177752, Group enriched (skeletal muscle, tongue)
neXtProtiNX_Q8N8F6
PharmGKBiPA142670550
VEuPathDBiHostDB:ENSG00000177752.14

GenAtlas: human gene database

More...
GenAtlasi
Search...

Phylogenomic databases

eggNOGiKOG3103, Eukaryota
GeneTreeiENSGT00940000153168
InParanoidiQ8N8F6
OMAiMLMSSGY
OrthoDBi1457080at2759
PhylomeDBiQ8N8F6
TreeFamiTF313100

Enzyme and pathway databases

PathwayCommonsiQ8N8F6

Miscellaneous databases

BioGRID ORCS database of CRISPR phenotype screens

More...
BioGRID-ORCSi
285525, 10 hits in 982 CRISPR screens

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...
GenomeRNAii
285525
PharosiQ8N8F6, Tdark

Protein Ontology

More...
PROi
PR:Q8N8F6
RNActiQ8N8F6, protein

Gene expression databases

BgeeiENSG00000177752, Expressed in quadriceps femoris and 98 other tissues
ExpressionAtlasiQ8N8F6, baseline and differential

Family and domain databases

InterProiView protein in InterPro
IPR006977, Yip1
PfamiView protein in Pfam
PF04893, Yip1, 1 hit

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiYIPF7_HUMAN
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q8N8F6
Secondary accession number(s): Q3SY21, Q3SY22
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: May 20, 2008
Last sequence update: May 20, 2008
Last modified: June 2, 2021
This is version 120 of the entry and version 2 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. Human chromosome 4
    Human chromosome 4: entries, gene names and cross-references to MIM
  2. Human entries with genetic variants
    List of human entries with genetic variants
  3. Human variants curated from literature reports
    Index of human variants curated from literature reports
  4. SIMILARITY comments
    Index of protein domains and families
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