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Protein

RNA-binding motif protein, X-linked-like-3

Gene

RBMXL3

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

Caution

Encoded in intron of the LRCH2 gene.Curated

GO - Molecular functioni

Keywordsi

Molecular functionRNA-binding

Names & Taxonomyi

Protein namesi
Recommended name:
RNA-binding motif protein, X-linked-like-3
Gene namesi
Name:RBMXL3
Synonyms:CXorf55
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome X

Organism-specific databases

EuPathDBiHostDB:ENSG00000175718.9
HGNCiHGNC:26859 RBMXL3
neXtProtiNX_Q8N7X1

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000175718
PharmGKBiPA164725338

Polymorphism and mutation databases

BioMutaiRBMXL3
DMDMi229485971

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002611761 – 1067RNA-binding motif protein, X-linked-like-3Add BLAST1067

Proteomic databases

EPDiQ8N7X1
MaxQBiQ8N7X1
PaxDbiQ8N7X1
PeptideAtlasiQ8N7X1
PRIDEiQ8N7X1
ProteomicsDBi72340

PTM databases

iPTMnetiQ8N7X1
PhosphoSitePlusiQ8N7X1

Expressioni

Gene expression databases

BgeeiENSG00000175718
CleanExiHS_CXorf55

Organism-specific databases

HPAiHPA051842

Interactioni

Protein-protein interaction databases

BioGridi126588, 2 interactors
STRINGi9606.ENSP00000417451

Structurei

3D structure databases

ProteinModelPortaliQ8N7X1
SMRiQ8N7X1
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini8 – 86RRMPROSITE-ProRule annotationAdd BLAST79

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Compositional biasi368 – 1063Gly-richAdd BLAST696

Phylogenomic databases

eggNOGiENOG410IXA2 Eukaryota
ENOG4111WRB LUCA
GeneTreeiENSGT00710000106295
HOGENOMiHOG000112105
InParanoidiQ8N7X1
KOiK12885
OMAiYEEYRGR
OrthoDBiEOG091G13K0
PhylomeDBiQ8N7X1
TreeFamiTF331833

Family and domain databases

Gene3Di3.30.70.330, 1 hit
InterProiView protein in InterPro
IPR012677 Nucleotide-bd_a/b_plait_sf
IPR035979 RBD_domain_sf
IPR000504 RRM_dom
PfamiView protein in Pfam
PF00076 RRM_1, 1 hit
SMARTiView protein in SMART
SM00360 RRM, 1 hit
SUPFAMiSSF54928 SSF54928, 1 hit
PROSITEiView protein in PROSITE
PS50102 RRM, 1 hit

Sequencei

Sequence statusi: Complete.

Q8N7X1-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MMEADRPEKL FIGGLNLKTD EKALKAEFGK YGHIIKVFLM KDRKTNKSRG
60 70 80 90 100
FAFVTFESPA DAKAAARDMN GKYLDGKAIM VAQTIKPAFK SSRWVPPTPG
110 120 130 140 150
SGSRSRFSHR TRGGGSSPQR PPSQGRPDDG RGYAGYFDLW PYRAPMPRKR
160 170 180 190 200
GPPPRHWASP PHKRATPSSL AHSVGCGMRG KAPTVSGQDG YSGLQPRRWA
210 220 230 240 250
GPPHKRAVPR SSLARIGGSG MPGKAPAVWG QDGYSGPRVR EPLPPCRDPG
260 270 280 290 300
DFVPALRDYS RRYYGHSSVP DYRPLRGDGN QNGYRGRDHE YTDHPSKGSY
310 320 330 340 350
REPLKSYGGP CGAAPVWGTP PSYGGGCRYE EYQGNSPDAC SEGRSSEALP
360 370 380 390 400
VVLPDAYSRD HSPKAYSGGR SSSSNGYSRS DRYGEEGCYE EYRGRSPDAH
410 420 430 440 450
SGGRNSSSNS YGQSHHYGGE GRYEEYRGRS HEARSGGRST DAHSRGRSDD
460 470 480 490 500
AYSGGHDSSS WSDCCGGGGR YEEYQGRSLD ANSGGCSPEA YSGGHDNSSW
510 520 530 540 550
SDRYGVGGHY EENRGHSLDA NSGGRSPDTH SGGHSSSSNS YGQSHRYGGE
560 570 580 590 600
GRYEYRGRSH DAHSGGCSAD AYSGGHDSSS QSNRYGGGGC YEEYRGRSLD
610 620 630 640 650
ANSGGRSPNA YSGGHDSSSW SHRYGGGGRY EEYRGRSLDA NSGGRSPDAY
660 670 680 690 700
SGGHDSSGQS NCYGGGGRYE EYRGRLLDAN SGGRSPDAYS GGHDSSSQSN
710 720 730 740 750
RYGGGGRYEE YRGHSLDANS GGRSPDTYSR GHDSSSQSDH YGGGGRSLDA
760 770 780 790 800
NSSGRLPDAY SGGHDSSSRS HRYGGGGRYE EYRGRSLDAN SGGRSPNAYS
810 820 830 840 850
GGHNSSSRND PCRGGGRYEE NRGHSLDANS GGHSPNAYSG GRDSSSNSYD
860 870 880 890 900
RSHRYGGGGH YEEYRGRSHD THSRGRSPDA HSGDHYTEAY SRGRDSFSNS
910 920 930 940 950
YGRSDHYGRG GCYEEYQGRS PNAYGGGRGL NSSNNSHGRS HRYGGGGRYE
960 970 980 990 1000
EYRGPSPDAH SGGRDSSIKS YGLSDRYGGG GHYEEYQGSL PDAYSGDHDR
1010 1020 1030 1040 1050
SSNSYGRSDR YSRGRDRVGR PDRGLPLPME TGSPPLHDSY SRSGCRVPRG
1060
GGRQGGRFER GEGRSRY
Length:1,067
Mass (Da):114,938
Last modified:March 24, 2009 - v2
Checksum:iCC8D0384670A38C5
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence conflicti394G → GRSPNAHSGG in BAG63332 (PubMed:14702039).Curated1
Sequence conflicti394G → GRSPNAHSGG in AK097568 (PubMed:14702039).Curated1
Sequence conflicti412G → S in AK097568 (PubMed:14702039).Curated1
Sequence conflicti640A → D in AK097568 (PubMed:14702039).Curated1
Sequence conflicti711Y → C in BAG63332 (PubMed:14702039).Curated1
Sequence conflicti723R → C in BAG63332 (PubMed:14702039).Curated1
Sequence conflicti723R → C in AK097568 (PubMed:14702039).Curated1
Sequence conflicti778R → H in BAG63332 (PubMed:14702039).Curated1
Sequence conflicti794R → H in AK097568 (PubMed:14702039).Curated1
Sequence conflicti921P → S in BAG63332 (PubMed:14702039).Curated1
Sequence conflicti1049R → G in BAG63332 (PubMed:14702039).Curated1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK301904 mRNA Translation: BAG63332.1
AK097568 mRNA No translation available.
AL589786 Genomic DNA No translation available.
CCDSiCCDS55478.1
RefSeqiNP_001138818.1, NM_001145346.1
UniGeneiHs.376008

Genome annotation databases

EnsembliENST00000424776; ENSP00000417451; ENSG00000175718
GeneIDi139804
KEGGihsa:139804
UCSCiuc011mte.2 human

Similar proteinsi

Entry informationi

Entry nameiRMXL3_HUMAN
AccessioniPrimary (citable) accession number: Q8N7X1
Secondary accession number(s): B4DXC0
Entry historyiIntegrated into UniProtKB/Swiss-Prot: November 28, 2006
Last sequence update: March 24, 2009
Last modified: June 20, 2018
This is version 100 of the entry and version 2 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Human chromosome X
    Human chromosome X: entries, gene names and cross-references to MIM

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