Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Entry version 146 (02 Jun 2021)
Sequence version 2 (29 May 2007)
Previous versions | rss
Add a publicationFeedback
Protein

Inactive phospholipase D5

Gene

PLD5

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:3 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at transcript leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Caution

In contrast to other members of the family, it lacks the conserved active sites, suggesting that it has no phospholipase activity.Curated

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

Enzyme and pathway databases

Pathway Commons web resource for biological pathway data

More...
PathwayCommonsi
Q8N7P1

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Inactive phospholipase D5
Short name:
Inactive PLD 5
Alternative name(s):
Inactive choline phosphatase 5
Inactive phosphatidylcholine-hydrolyzing phospholipase D5
PLDc
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:PLD5
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 1

Organism-specific databases

Human Gene Nomenclature Database

More...
HGNCi
HGNC:26879, PLD5

neXtProt; the human protein knowledge platform

More...
neXtProti
NX_Q8N7P1

Eukaryotic Pathogen, Vector and Host Database Resources

More...
VEuPathDBi
HostDB:ENSG00000180287.16

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular%5Flocation%5Fsection">'Subcellular location'</a> section describes the extent of a membrane-spanning region of the protein. It denotes the presence of both alpha-helical transmembrane regions and the membrane spanning regions of beta-barrel transmembrane proteins.<p><a href='/help/transmem' target='_top'>More...</a></p>Transmembranei69 – 89HelicalSequence analysisAdd BLAST21

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Cellular componenti

Membrane

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

DisGeNET

More...
DisGeNETi
200150

Open Targets

More...
OpenTargetsi
ENSG00000180287

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...
PharmGKBi
PA142671168

Miscellaneous databases

Pharos NIH Druggable Genome Knowledgebase

More...
Pharosi
Q8N7P1, Tbio

Genetic variation databases

BioMuta curated single-nucleotide variation and disease association database

More...
BioMutai
PLD5

Domain mapping of disease mutations (DMDM)

More...
DMDMi
152112223

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00002886061 – 536Inactive phospholipase D5Add BLAST536

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/ptm%5Fprocessing%5Fsection">PTM / Processing</a> section specifies the position and type of each covalently attached glycan group (mono-, di-, or polysaccharide).<p><a href='/help/carbohyd' target='_top'>More...</a></p>Glycosylationi121N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi302N-linked (GlcNAc...) asparagineSequence analysis1

Keywords - PTMi

Glycoprotein

Proteomic databases

Encyclopedia of Proteome Dynamics

More...
EPDi
Q8N7P1

jPOST - Japan Proteome Standard Repository/Database

More...
jPOSTi
Q8N7P1

MassIVE - Mass Spectrometry Interactive Virtual Environment

More...
MassIVEi
Q8N7P1

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q8N7P1

PeptideAtlas

More...
PeptideAtlasi
Q8N7P1

PRoteomics IDEntifications database

More...
PRIDEi
Q8N7P1

ProteomicsDB: a multi-organism proteome resource

More...
ProteomicsDBi
72311 [Q8N7P1-1]
72312 [Q8N7P1-2]
72313 [Q8N7P1-3]
72314 [Q8N7P1-4]

PTM databases

GlyGen: Computational and Informatics Resources for Glycoscience

More...
GlyGeni
Q8N7P1, 2 sites

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
Q8N7P1

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
Q8N7P1

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSG00000180287, Expressed in pigmented layer of retina and 129 other tissues

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
Q8N7P1, baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
Q8N7P1, HS

Organism-specific databases

Human Protein Atlas

More...
HPAi
ENSG00000180287, Group enriched (brain, retina)

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGRID)

More...
BioGRIDi
128302, 1 interactor

STRING: functional protein association networks

More...
STRINGi
9606.ENSP00000440896

Miscellaneous databases

RNAct, Protein-RNA interaction predictions for model organisms.

More...
RNActi
Q8N7P1, protein

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
Q8N7P1

Database of comparative protein structure models

More...
ModBasei
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini215 – 242PLD phosphodiesterase 1Add BLAST28
Domaini434 – 460PLD phosphodiesterase 2Add BLAST27

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the phospholipase D family.Curated

Keywords - Domaini

Repeat, Transmembrane, Transmembrane helix

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG3603, Eukaryota

Ensembl GeneTree

More...
GeneTreei
ENSGT00950000183059

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
CLU_027021_0_0_1

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q8N7P1

Identification of Orthologs from Complete Genome Data

More...
OMAi
CMQLHNC

Database of Orthologous Groups

More...
OrthoDBi
1057467at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q8N7P1

TreeFam database of animal gene trees

More...
TreeFami
TF313378

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR032803, PLDc_3
IPR001736, PLipase_D/transphosphatidylase

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF13918, PLDc_3, 1 hit

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00155, PLDc, 2 hits

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequences (4+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry describes 4 <p>This subsection of the 'Sequence' section lists the alternative protein sequences (isoforms) that can be generated from the same gene by a single or by the combination of up to four biological events (alternative promoter usage, alternative splicing, alternative initiation and ribosomal frameshifting). Additionally, this section gives relevant information on each alternative protein isoform.<p><a href='/help/alternative_products' target='_top'>More...</a></p> isoformsi produced by alternative splicing. AlignAdd to basket

This entry has 4 described isoforms and 4 potential isoforms that are computationally mapped.Show allAlign All

Isoform 1 (identifier: Q8N7P1-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the <div> <p><b>What is the canonical sequence?</b><p><a href='/help/canonical_and_isoforms' target='_top'>More...</a></p>canonicali sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide
        10         20         30         40         50
MEIRQHEWLS ASPHEGFEQM RLKSRPKEPS PSLTRVGANF YSSVKQQDYS
60 70 80 90 100
ASVWLRRKDK LEHSQQKCIV IFALVCCFAI LVALIFSAVD IMGEDEDGLS
110 120 130 140 150
EKNCQNKCRI ALVENIPEGL NYSENAPFHL SLFQGWMNLL NMAKKSVDIV
160 170 180 190 200
SSHWDLNHTH PSACQGQRLF EKLLQLTSQN IEIKLVSDVT ADSKVLEALK
210 220 230 240 250
LKGAEVTYMN MTAYNKGRLQ SSFWIVDKQH VYIGSAGLDW QSLGQMKELG
260 270 280 290 300
VIFYNCSCLV LDLQRIFALY SSLKFKSRVP QTWSKRLYGV YDNEKKLQLQ
310 320 330 340 350
LNETKSQAFV SNSPKLFCPK NRSFDIDAIY SVIDDAKQYV YIAVMDYLPI
360 370 380 390 400
SSTSTKRTYW PDLDAKIREA LVLRSVRVRL LLSFWKETDP LTFNFISSLK
410 420 430 440 450
AICTEIANCS LKVKFFDLER ENACATKEQK NHTFPRLNRN KYMVTDGAAY
460 470 480 490 500
IGNFDWVGND FTQNAGTGLV INQADVRNNR SIIKQLKDVF ERDWYSPYAK
510 520 530
TLQPTKQPNC SSLFKLKPLS NKTATDDTGG KDPRNV
Length:536
Mass (Da):61,312
Last modified:May 29, 2007 - v2
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i2FC94D6AB4A19934
GO
Isoform 2 (identifier: Q8N7P1-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     1-108: MEIRQHEWLS...LSEKNCQNKC → MRMDSQKKIAKINVGK

Show »
Length:444
Mass (Da):50,795
Checksum:i71582866A7BE84DC
GO
Isoform 3 (identifier: Q8N7P1-3) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     1-208: Missing.

Show »
Length:328
Mass (Da):37,736
Checksum:i38A06E30E98C3D57
GO
Isoform 4 (identifier: Q8N7P1-4) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     1-62: Missing.
     63-63: H → M

Show »
Length:474
Mass (Da):53,990
Checksum:iD8B8CBD3D9DB4436
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 4 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
J3KP61J3KP61_HUMAN
Inactive phospholipase D5
PLD5
109Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
F5GXZ8F5GXZ8_HUMAN
Inactive phospholipase D5
PLD5
197Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
F8W7H1F8W7H1_HUMAN
Inactive phospholipase D5
PLD5
47Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
F5H329F5H329_HUMAN
Inactive phospholipase D5
PLD5
140Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

<p>This subsection of the 'Sequence' section reports difference(s) between the protein sequence shown in the UniProtKB entry and other available protein sequences derived from the same gene.<p><a href='/help/sequence_caution' target='_top'>More...</a></p>Sequence cautioni

The sequence AAI01374 differs from that shown. Reason: Erroneous initiation.Curated
The sequence AAI01375 differs from that shown. Reason: Erroneous initiation.Curated
The sequence AAI01376 differs from that shown. Reason: Erroneous initiation.Curated

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section describes the sequence of naturally occurring alternative protein isoform(s). The changes in the amino acid sequence may be due to alternative splicing, alternative promoter usage, alternative initiation, or ribosomal frameshifting.<p><a href='/help/var_seq' target='_top'>More...</a></p>Alternative sequenceiVSP_0257241 – 208Missing in isoform 3. 1 PublicationAdd BLAST208
Alternative sequenceiVSP_0257251 – 108MEIRQ…CQNKC → MRMDSQKKIAKINVGK in isoform 2. 1 PublicationAdd BLAST108
Alternative sequenceiVSP_0257261 – 62Missing in isoform 4. 2 PublicationsAdd BLAST62
Alternative sequenceiVSP_02572763H → M in isoform 4. 2 Publications1

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AY461578 mRNA Translation: AAS91020.1
AK091691 mRNA Translation: BAC03722.1
AK098092 mRNA Translation: BAC05230.1
AK295421 mRNA Translation: BAH12060.1
AL360271 Genomic DNA No translation available.
AL583845 Genomic DNA No translation available.
AL591686 Genomic DNA No translation available.
AL445704 Genomic DNA No translation available.
BC101373 mRNA Translation: AAI01374.1 Different initiation.
BC101374 mRNA Translation: AAI01375.1 Different initiation.
BC101375 mRNA Translation: AAI01376.1 Different initiation.

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS1621.2 [Q8N7P1-1]
CCDS55692.1 [Q8N7P1-4]

NCBI Reference Sequences

More...
RefSeqi
NP_001182740.1, NM_001195811.1 [Q8N7P1-4]
NP_001182741.1, NM_001195812.1 [Q8N7P1-3]
NP_001307201.1, NM_001320272.1 [Q8N7P1-2]
NP_689879.2, NM_152666.2
XP_006711815.1, XM_006711752.2
XP_011542417.1, XM_011544115.2
XP_011542418.1, XM_011544116.2
XP_011542422.1, XM_011544120.2 [Q8N7P1-3]
XP_011542423.1, XM_011544121.2 [Q8N7P1-3]
XP_011542424.1, XM_011544122.2 [Q8N7P1-3]
XP_016856056.1, XM_017000567.1 [Q8N7P1-2]
XP_016856057.1, XM_017000568.1 [Q8N7P1-2]
XP_016856058.1, XM_017000569.1 [Q8N7P1-3]
XP_016856059.1, XM_017000570.1 [Q8N7P1-3]

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENST00000427495; ENSP00000401285; ENSG00000180287 [Q8N7P1-4]
ENST00000442594; ENSP00000414188; ENSG00000180287 [Q8N7P1-1]
ENST00000536534; ENSP00000440896; ENSG00000180287 [Q8N7P1-1]

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
200150

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
hsa:200150

UCSC genome browser

More...
UCSCi
uc001hzl.4, human [Q8N7P1-1]

Keywords - Coding sequence diversityi

Alternative splicing

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AY461578 mRNA Translation: AAS91020.1
AK091691 mRNA Translation: BAC03722.1
AK098092 mRNA Translation: BAC05230.1
AK295421 mRNA Translation: BAH12060.1
AL360271 Genomic DNA No translation available.
AL583845 Genomic DNA No translation available.
AL591686 Genomic DNA No translation available.
AL445704 Genomic DNA No translation available.
BC101373 mRNA Translation: AAI01374.1 Different initiation.
BC101374 mRNA Translation: AAI01375.1 Different initiation.
BC101375 mRNA Translation: AAI01376.1 Different initiation.
CCDSiCCDS1621.2 [Q8N7P1-1]
CCDS55692.1 [Q8N7P1-4]
RefSeqiNP_001182740.1, NM_001195811.1 [Q8N7P1-4]
NP_001182741.1, NM_001195812.1 [Q8N7P1-3]
NP_001307201.1, NM_001320272.1 [Q8N7P1-2]
NP_689879.2, NM_152666.2
XP_006711815.1, XM_006711752.2
XP_011542417.1, XM_011544115.2
XP_011542418.1, XM_011544116.2
XP_011542422.1, XM_011544120.2 [Q8N7P1-3]
XP_011542423.1, XM_011544121.2 [Q8N7P1-3]
XP_011542424.1, XM_011544122.2 [Q8N7P1-3]
XP_016856056.1, XM_017000567.1 [Q8N7P1-2]
XP_016856057.1, XM_017000568.1 [Q8N7P1-2]
XP_016856058.1, XM_017000569.1 [Q8N7P1-3]
XP_016856059.1, XM_017000570.1 [Q8N7P1-3]

3D structure databases

SMRiQ8N7P1
ModBaseiSearch...

Protein-protein interaction databases

BioGRIDi128302, 1 interactor
STRINGi9606.ENSP00000440896

PTM databases

GlyGeniQ8N7P1, 2 sites
iPTMnetiQ8N7P1
PhosphoSitePlusiQ8N7P1

Genetic variation databases

BioMutaiPLD5
DMDMi152112223

Proteomic databases

EPDiQ8N7P1
jPOSTiQ8N7P1
MassIVEiQ8N7P1
PaxDbiQ8N7P1
PeptideAtlasiQ8N7P1
PRIDEiQ8N7P1
ProteomicsDBi72311 [Q8N7P1-1]
72312 [Q8N7P1-2]
72313 [Q8N7P1-3]
72314 [Q8N7P1-4]

Protocols and materials databases

Antibodypedia a portal for validated antibodies

More...
Antibodypediai
34707, 122 antibodies

The DNASU plasmid repository

More...
DNASUi
200150

Genome annotation databases

EnsembliENST00000427495; ENSP00000401285; ENSG00000180287 [Q8N7P1-4]
ENST00000442594; ENSP00000414188; ENSG00000180287 [Q8N7P1-1]
ENST00000536534; ENSP00000440896; ENSG00000180287 [Q8N7P1-1]
GeneIDi200150
KEGGihsa:200150
UCSCiuc001hzl.4, human [Q8N7P1-1]

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
200150
DisGeNETi200150

GeneCards: human genes, protein and diseases

More...
GeneCardsi
PLD5
HGNCiHGNC:26879, PLD5
HPAiENSG00000180287, Group enriched (brain, retina)
neXtProtiNX_Q8N7P1
OpenTargetsiENSG00000180287
PharmGKBiPA142671168
VEuPathDBiHostDB:ENSG00000180287.16

GenAtlas: human gene database

More...
GenAtlasi
Search...

Phylogenomic databases

eggNOGiKOG3603, Eukaryota
GeneTreeiENSGT00950000183059
HOGENOMiCLU_027021_0_0_1
InParanoidiQ8N7P1
OMAiCMQLHNC
OrthoDBi1057467at2759
PhylomeDBiQ8N7P1
TreeFamiTF313378

Enzyme and pathway databases

PathwayCommonsiQ8N7P1

Miscellaneous databases

BioGRID ORCS database of CRISPR phenotype screens

More...
BioGRID-ORCSi
200150, 8 hits in 981 CRISPR screens

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...
ChiTaRSi
PLD5, human

The Gene Wiki collection of pages on human genes and proteins

More...
GeneWikii
PLD5

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...
GenomeRNAii
200150
PharosiQ8N7P1, Tbio

Protein Ontology

More...
PROi
PR:Q8N7P1
RNActiQ8N7P1, protein

Gene expression databases

BgeeiENSG00000180287, Expressed in pigmented layer of retina and 129 other tissues
ExpressionAtlasiQ8N7P1, baseline and differential
GenevisibleiQ8N7P1, HS

Family and domain databases

InterProiView protein in InterPro
IPR032803, PLDc_3
IPR001736, PLipase_D/transphosphatidylase
PfamiView protein in Pfam
PF13918, PLDc_3, 1 hit
SMARTiView protein in SMART
SM00155, PLDc, 2 hits

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiPLD5_HUMAN
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q8N7P1
Secondary accession number(s): A1KXV0
, B7Z324, Q494U9, Q8NB22
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: May 29, 2007
Last sequence update: May 29, 2007
Last modified: June 2, 2021
This is version 146 of the entry and version 2 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. Human chromosome 1
    Human chromosome 1: entries, gene names and cross-references to MIM
  2. SIMILARITY comments
    Index of protein domains and families
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.

Do not show this banner again