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Protein
Submitted name:

TRAF3-interacting protein 2

Gene

Traf3ip2

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

  • signaling receptor binding Source: UniProtKB

GO - Biological processi

  • B cell apoptotic process Source: MGI
  • humoral immune response Source: MGI
  • immunoglobulin secretion Source: MGI
  • positive regulation of defense response to virus by host Source: MGI
  • positive regulation of I-kappaB kinase/NF-kappaB signaling Source: GO_Central

Names & Taxonomyi

Protein namesi
Submitted name:
TRAF3-interacting protein 2Imported
Submitted name:
cDNA fis, clone TRACH2006870,moderately similar to Homo sapiens adaptor protein CIKS mRNAImported
Gene namesi
Name:Traf3ip2Imported
ORF Names:mCG_1382Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 10

Organism-specific databases

MGIiMGI:2143599 Traf3ip2

Expressioni

Gene expression databases

BgeeiENSMUSG00000019842 Expressed in 220 organ(s), highest expression level in prostate gland ventral lobe

Interactioni

Binary interactionsi

GO - Molecular functioni

Protein-protein interaction databases

IntActiQ8N7N6, 8 interactors
Q8N7N6, 8 interactors
STRINGi10090.ENSMUSP00000019987

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini390 – 531SEFIRInterPro annotationAdd BLAST142

Phylogenomic databases

eggNOGiENOG410IF9W Eukaryota
ENOG4111GTJ LUCA
GeneTreeiENSGT00390000007714
HOVERGENiHBG002060
KOiK21124
OMAiKTVMIII
OrthoDBiEOG091G04TE
TreeFamiTF329063

Family and domain databases

InterProiView protein in InterPro
IPR013568 SEFIR_dom
PfamiView protein in Pfam
PF08357 SEFIR, 1 hit
PROSITEiView protein in PROSITE
PS51534 SEFIR, 1 hit

Sequencei

Sequence statusi: Complete.

Q8N7N6-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MNRSIPVEVD ESEPFPSQLL KPIPEYSPEE ELEPPAPNTR NMAPSSLSVL
60 70 80 90 100
QCPPLKLANH QPVSQQVTCL RAKVLEEGEA SFFRRHPELG KDISSCSSGA
110 120 130 140 150
SEPESELGAL PPEHRFTLTE KRNRWLGSQL SAASPDTGHE SDKSDPSLPN
160 170 180 190 200
ALADSFSGGQ EMMPRPRPRP GPHRHRAAPD VPTIDTGYDS QPQDVLGIRQ
210 220 230 240 250
LERPLPLTSS CYLQDLPGPL RSRELPPQFE LERYPMNAQL LPPHPSPQAP
260 270 280 290 300
WNCQYYCPGG PYHHQVPHGH GYPPAAAYQQ VLQPALPGQV LPGARARGPR
310 320 330 340 350
PVQKVILNDS SPQDQEERPA QRDFSFPRLP RDQLYRPPSN GVEAPEESLD
360 370 380 390 400
LPAELRPHGP QAPSLAAVPR PPSNPLARGT LRTSNLPEEL RKVFITYSMD
410 420 430 440 450
TAMEVVKFVN FLLVNGFQTA IDIFEDRIRG IDIIKWMERY LRDKTVMIIV
460 470 480 490 500
AISPKYKQDV EGAESQLDED EHGLHTKYIH RMMQIEFISQ GSMNFRFIPV
510 520 530 540 550
LFPNAKKEHV PTWLQNTHVY SWPKNKKNIL LRLLREEEYV APPRGPLPTL

QVVPL
Length:555
Mass (Da):62,440
Last modified:October 1, 2002 - v1
Checksum:i54B40C8D81C3D827
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC160403 Genomic DNA No translation available.
BC096483 mRNA Translation: AAH96483.1
BC138234 mRNA Translation: AAI38235.1
BC138235 mRNA Translation: AAI38236.1
JX869941 mRNA Translation: AFY98903.1
AK098107 mRNA Translation: BAC05236.1
AK037407 mRNA Translation: BAC29801.1
AK052190 mRNA Translation: BAC34875.1
CH466540 Genomic DNA Translation: EDL04930.1
RefSeqiNP_598761.2, NM_134000.3
UniGeneiMm.436686

Genome annotation databases

EnsembliENSMUST00000019987; ENSMUSP00000019987; ENSMUSG00000019842
GeneIDi103213
KEGGimmu:103213
UCSCiuc007ewa.1 mouse

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC160403 Genomic DNA No translation available.
BC096483 mRNA Translation: AAH96483.1
BC138234 mRNA Translation: AAI38235.1
BC138235 mRNA Translation: AAI38236.1
JX869941 mRNA Translation: AFY98903.1
AK098107 mRNA Translation: BAC05236.1
AK037407 mRNA Translation: BAC29801.1
AK052190 mRNA Translation: BAC34875.1
CH466540 Genomic DNA Translation: EDL04930.1
RefSeqiNP_598761.2, NM_134000.3
UniGeneiMm.436686

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

IntActiQ8N7N6, 8 interactors
Q8N7N6, 8 interactors
STRINGi10090.ENSMUSP00000019987

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000019987; ENSMUSP00000019987; ENSMUSG00000019842
GeneIDi103213
KEGGimmu:103213
UCSCiuc007ewa.1 mouse

Organism-specific databases

CTDi10758
MGIiMGI:2143599 Traf3ip2

Phylogenomic databases

eggNOGiENOG410IF9W Eukaryota
ENOG4111GTJ LUCA
GeneTreeiENSGT00390000007714
HOVERGENiHBG002060
KOiK21124
OMAiKTVMIII
OrthoDBiEOG091G04TE
TreeFamiTF329063

Miscellaneous databases

ChiTaRSiTraf3ip2 mouse
SOURCEiSearch...

Gene expression databases

BgeeiENSMUSG00000019842 Expressed in 220 organ(s), highest expression level in prostate gland ventral lobe

Family and domain databases

InterProiView protein in InterPro
IPR013568 SEFIR_dom
PfamiView protein in Pfam
PF08357 SEFIR, 1 hit
PROSITEiView protein in PROSITE
PS51534 SEFIR, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiQ8N7N6_MOUSE
AccessioniPrimary (citable) accession number: Q8N7N6
Secondary accession number(s): Q8BH33
Entry historyiIntegrated into UniProtKB/TrEMBL: October 1, 2002
Last sequence update: October 1, 2002
Last modified: November 7, 2018
This is version 131 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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