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Entry version 116 (08 May 2019)
Sequence version 2 (20 Feb 2007)
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Protein

PACRG-like protein

Gene

PACRGL

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
PACRG-like protein
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:PACRGL
Synonyms:C4orf28
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 4

Organism-specific databases

Human Gene Nomenclature Database

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HGNCi
HGNC:28442 PACRGL

neXtProt; the human protein knowledge platform

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neXtProti
NX_Q8N7B6

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

Open Targets

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OpenTargetsi
ENSG00000163138

The Pharmacogenetics and Pharmacogenomics Knowledge Base

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PharmGKBi
PA164724318

Polymorphism and mutation databases

BioMuta curated single-nucleotide variation and disease association database

More...
BioMutai
PACRGL

Domain mapping of disease mutations (DMDM)

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DMDMi
126215685

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00002782431 – 248PACRG-like proteinAdd BLAST248

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei1N-acetylmethionineCombined sources1
Modified residuei47PhosphoserineBy similarity1

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - PTMi

Acetylation, Phosphoprotein

Proteomic databases

MaxQB - The MaxQuant DataBase

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MaxQBi
Q8N7B6

PeptideAtlas

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PeptideAtlasi
Q8N7B6

PRoteomics IDEntifications database

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PRIDEi
Q8N7B6

ProteomicsDB human proteome resource

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ProteomicsDBi
72280
72281 [Q8N7B6-2]
72282 [Q8N7B6-3]

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

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iPTMneti
Q8N7B6

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

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PhosphoSitePlusi
Q8N7B6

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

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Bgeei
ENSG00000163138 Expressed in 174 organ(s), highest expression level in sperm

ExpressionAtlas, Differential and Baseline Expression

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ExpressionAtlasi
Q8N7B6 baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

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Genevisiblei
Q8N7B6 HS

Organism-specific databases

Human Protein Atlas

More...
HPAi
HPA054666

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the '<a href="http://www.uniprot.org/help/interaction_section%27">Interaction</a> section provides information about binary protein-protein interactions. The data presented in this section are a quality-filtered subset of binary interactions automatically derived from the <a href="http://www.ebi.ac.uk/intact/">IntAct database</a>. It is updated on a monthly basis. Each binary interaction is displayed on a separate line.<p><a href='/help/binary_interactions' target='_top'>More...</a></p>Binary interactionsi

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGrid)

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BioGridi
126346, 5 interactors

Protein interaction database and analysis system

More...
IntActi
Q8N7B6, 13 interactors

STRING: functional protein association networks

More...
STRINGi
9606.ENSP00000423881

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

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SMRi
Q8N7B6

Database of comparative protein structure models

More...
ModBasei
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Phylogenomic databases

Ensembl GeneTree

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GeneTreei
ENSGT00940000159756

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

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HOGENOMi
HOG000068031

InParanoid: Eukaryotic Ortholog Groups

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InParanoidi
Q8N7B6

Identification of Orthologs from Complete Genome Data

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OMAi
MQKSECH

Database of Orthologous Groups

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OrthoDBi
1327344at2759

Database for complete collections of gene phylogenies

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PhylomeDBi
Q8N7B6

TreeFam database of animal gene trees

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TreeFami
TF321123

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

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Gene3Di
1.25.10.10, 1 hit

Integrated resource of protein families, domains and functional sites

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InterProi
View protein in InterPro
IPR011989 ARM-like
IPR016024 ARM-type_fold
IPR019399 Parkin_co-regulated_protein

The PANTHER Classification System

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PANTHERi
PTHR21207 PTHR21207, 1 hit

Pfam protein domain database

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Pfami
View protein in Pfam
PF10274 ParcG, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF48371 SSF48371, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequences (4+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry describes 4 <p>This subsection of the ‘Sequence’ section lists the alternative protein sequences (isoforms) that can be generated from the same gene by a single or by the combination of up to four biological events (alternative promoter usage, alternative splicing, alternative initiation and ribosomal frameshifting). Additionally, this section gives relevant information on each alternative protein isoform.<p><a href='/help/alternative_products' target='_top'>More...</a></p> isoformsi produced by alternative splicing. AlignAdd to basket

This entry has 4 described isoforms and 19 potential isoforms that are computationally mapped.Show allAlign All

Isoform 1 (identifier: Q8N7B6-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the <div> <p><b>What is the canonical sequence?</b><p><a href='/help/canonical_and_isoforms' target='_top'>More...</a></p>canonicali sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide
        10         20         30         40         50
MQKSEGSGGT QLKNRATGNY DQRTSSSTQL KHRNAVQGSK SSLSTSSPES
60 70 80 90 100
ARKLHPRPSD KLNPKTINPF GEQSRVPSAF AAIYSKGGIP CRLVHGSVKH
110 120 130 140 150
RLQWECPPES LSFDPLLITL AEGLRETKHP YTFVSKEGFR ELLLVKGAPE
160 170 180 190 200
KAIPLLPRLI PVLKAALVHS DDEVFERGLN ALVQLSVVVG PSLNDHLKHL
210 220 230 240
LTSLSKRLMD KKFKEPITSA LQKLEQHGGS GSLSIIKSKI PTYCSICC
Length:248
Mass (Da):27,152
Last modified:February 20, 2007 - v2
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i01E1EB06F10E85F7
GO
Isoform 2 (identifier: Q8N7B6-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     203-229: Missing.

Show »
Length:221
Mass (Da):24,100
Checksum:i2BB975BCBF8984DD
GO
Isoform 3 (identifier: Q8N7B6-3) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     70-167: Missing.
     203-229: Missing.

Note: No experimental confirmation available.
Show »
Length:123
Mass (Da):13,285
Checksum:i9027DB129B1F8943
GO
Isoform 4 (identifier: Q8N7B6-4) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     70-122: Missing.
     204-248: LSKRLMDKKF...KIPTYCSICC → DPVQLMRFPR...IKIKISKGEP

Show »
Length:200
Mass (Da):22,059
Checksum:i89A783D4CDBD3B26
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 19 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
D6RGK2D6RGK2_HUMAN
PACRG-like protein
PACRGL
168Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
D6RC13D6RC13_HUMAN
PACRG-like protein
PACRGL
203Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
D6RF51D6RF51_HUMAN
PACRG-like protein
PACRGL
122Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
D6R9N9D6R9N9_HUMAN
PACRG-like protein
PACRGL
245Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
D6R9D1D6R9D1_HUMAN
PACRG-like protein
PACRGL
136Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
D6RAM4D6RAM4_HUMAN
PACRG-like protein
PACRGL
150Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
D6R9F1D6R9F1_HUMAN
PACRG-like protein
PACRGL
85Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
D6REQ4D6REQ4_HUMAN
PACRG-like protein
PACRGL
87Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
D6RC23D6RC23_HUMAN
PACRG-like protein
PACRGL
142Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
D6RF08D6RF08_HUMAN
PACRG-like protein
PACRGL
102Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
There are more potential isoformsShow all

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti104W → R in BAC05381 (PubMed:14702039).Curated1

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section describes the sequence of naturally occurring alternative protein isoform(s). The changes in the amino acid sequence may be due to alternative splicing, alternative promoter usage, alternative initiation, or ribosomal frameshifting.<p><a href='/help/var_seq' target='_top'>More...</a></p>Alternative sequenceiVSP_04335170 – 167Missing in isoform 3. 1 PublicationAdd BLAST98
Alternative sequenceiVSP_04509570 – 122Missing in isoform 4. 1 PublicationAdd BLAST53
Alternative sequenceiVSP_023206203 – 229Missing in isoform 2 and isoform 3. 2 PublicationsAdd BLAST27
Alternative sequenceiVSP_045096204 – 248LSKRL…CSICC → DPVQLMRFPRPLLGLMICQK DPWNSGKLLLAVMVSYNTQK IKIKISKGEP in isoform 4. 1 PublicationAdd BLAST45

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AK098692 mRNA Translation: BAC05381.1
AK297556 mRNA Translation: BAG59949.1
AK315482 mRNA Translation: BAG37866.1
AK294077 mRNA Translation: BAG57419.1
AC097505 Genomic DNA No translation available.
AC104065 Genomic DNA Translation: AAY40910.1
BC023002 mRNA Translation: AAH23002.1

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS3427.1 [Q8N7B6-2]
CCDS47034.1 [Q8N7B6-3]
CCDS58895.1 [Q8N7B6-1]
CCDS58896.1 [Q8N7B6-4]

NCBI Reference Sequences

More...
RefSeqi
NP_001124199.1, NM_001130727.2 [Q8N7B6-3]
NP_001245274.1, NM_001258345.2 [Q8N7B6-1]
NP_001245275.1, NM_001258346.2 [Q8N7B6-4]
NP_001317674.1, NM_001330745.1
NP_001317675.1, NM_001330746.1
NP_001317676.1, NM_001330747.1
NP_001317677.1, NM_001330748.1
NP_659485.1, NM_145048.4 [Q8N7B6-2]
XP_011512107.1, XM_011513805.2 [Q8N7B6-2]
XP_016863237.1, XM_017007748.1 [Q8N7B6-1]
XP_016863238.1, XM_017007749.1 [Q8N7B6-1]
XP_016863240.1, XM_017007751.1 [Q8N7B6-2]
XP_016863241.1, XM_017007752.1 [Q8N7B6-2]
XP_016863242.1, XM_017007753.1 [Q8N7B6-2]
XP_016863247.1, XM_017007758.1 [Q8N7B6-3]
XP_016863248.1, XM_017007759.1 [Q8N7B6-3]

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENST00000295290; ENSP00000295290; ENSG00000163138 [Q8N7B6-2]
ENST00000360916; ENSP00000354171; ENSG00000163138 [Q8N7B6-2]
ENST00000444671; ENSP00000415832; ENSG00000163138 [Q8N7B6-3]
ENST00000467997; ENSP00000423477; ENSG00000163138 [Q8N7B6-2]
ENST00000471979; ENSP00000423914; ENSG00000163138 [Q8N7B6-1]
ENST00000502374; ENSP00000425461; ENSG00000163138 [Q8N7B6-4]
ENST00000503585; ENSP00000423881; ENSG00000163138 [Q8N7B6-1]
ENST00000506702; ENSP00000423536; ENSG00000163138 [Q8N7B6-2]
ENST00000507634; ENSP00000425938; ENSG00000163138 [Q8N7B6-2]

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
133015

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
hsa:133015

UCSC genome browser

More...
UCSCi
uc003gpu.4 human [Q8N7B6-1]

Keywords - Coding sequence diversityi

Alternative splicing

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK098692 mRNA Translation: BAC05381.1
AK297556 mRNA Translation: BAG59949.1
AK315482 mRNA Translation: BAG37866.1
AK294077 mRNA Translation: BAG57419.1
AC097505 Genomic DNA No translation available.
AC104065 Genomic DNA Translation: AAY40910.1
BC023002 mRNA Translation: AAH23002.1
CCDSiCCDS3427.1 [Q8N7B6-2]
CCDS47034.1 [Q8N7B6-3]
CCDS58895.1 [Q8N7B6-1]
CCDS58896.1 [Q8N7B6-4]
RefSeqiNP_001124199.1, NM_001130727.2 [Q8N7B6-3]
NP_001245274.1, NM_001258345.2 [Q8N7B6-1]
NP_001245275.1, NM_001258346.2 [Q8N7B6-4]
NP_001317674.1, NM_001330745.1
NP_001317675.1, NM_001330746.1
NP_001317676.1, NM_001330747.1
NP_001317677.1, NM_001330748.1
NP_659485.1, NM_145048.4 [Q8N7B6-2]
XP_011512107.1, XM_011513805.2 [Q8N7B6-2]
XP_016863237.1, XM_017007748.1 [Q8N7B6-1]
XP_016863238.1, XM_017007749.1 [Q8N7B6-1]
XP_016863240.1, XM_017007751.1 [Q8N7B6-2]
XP_016863241.1, XM_017007752.1 [Q8N7B6-2]
XP_016863242.1, XM_017007753.1 [Q8N7B6-2]
XP_016863247.1, XM_017007758.1 [Q8N7B6-3]
XP_016863248.1, XM_017007759.1 [Q8N7B6-3]

3D structure databases

SMRiQ8N7B6
ModBaseiSearch...

Protein-protein interaction databases

BioGridi126346, 5 interactors
IntActiQ8N7B6, 13 interactors
STRINGi9606.ENSP00000423881

PTM databases

iPTMnetiQ8N7B6
PhosphoSitePlusiQ8N7B6

Polymorphism and mutation databases

BioMutaiPACRGL
DMDMi126215685

Proteomic databases

MaxQBiQ8N7B6
PeptideAtlasiQ8N7B6
PRIDEiQ8N7B6
ProteomicsDBi72280
72281 [Q8N7B6-2]
72282 [Q8N7B6-3]

Protocols and materials databases

The DNASU plasmid repository

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DNASUi
133015
Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000295290; ENSP00000295290; ENSG00000163138 [Q8N7B6-2]
ENST00000360916; ENSP00000354171; ENSG00000163138 [Q8N7B6-2]
ENST00000444671; ENSP00000415832; ENSG00000163138 [Q8N7B6-3]
ENST00000467997; ENSP00000423477; ENSG00000163138 [Q8N7B6-2]
ENST00000471979; ENSP00000423914; ENSG00000163138 [Q8N7B6-1]
ENST00000502374; ENSP00000425461; ENSG00000163138 [Q8N7B6-4]
ENST00000503585; ENSP00000423881; ENSG00000163138 [Q8N7B6-1]
ENST00000506702; ENSP00000423536; ENSG00000163138 [Q8N7B6-2]
ENST00000507634; ENSP00000425938; ENSG00000163138 [Q8N7B6-2]
GeneIDi133015
KEGGihsa:133015
UCSCiuc003gpu.4 human [Q8N7B6-1]

Organism-specific databases

Comparative Toxicogenomics Database

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CTDi
133015

GeneCards: human genes, protein and diseases

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GeneCardsi
PACRGL
HGNCiHGNC:28442 PACRGL
HPAiHPA054666
neXtProtiNX_Q8N7B6
OpenTargetsiENSG00000163138
PharmGKBiPA164724318

GenAtlas: human gene database

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GenAtlasi
Search...

Phylogenomic databases

GeneTreeiENSGT00940000159756
HOGENOMiHOG000068031
InParanoidiQ8N7B6
OMAiMQKSECH
OrthoDBi1327344at2759
PhylomeDBiQ8N7B6
TreeFamiTF321123

Miscellaneous databases

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

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ChiTaRSi
PACRGL human

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

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GenomeRNAii
133015

Protein Ontology

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PROi
PR:Q8N7B6

Gene expression databases

BgeeiENSG00000163138 Expressed in 174 organ(s), highest expression level in sperm
ExpressionAtlasiQ8N7B6 baseline and differential
GenevisibleiQ8N7B6 HS

Family and domain databases

Gene3Di1.25.10.10, 1 hit
InterProiView protein in InterPro
IPR011989 ARM-like
IPR016024 ARM-type_fold
IPR019399 Parkin_co-regulated_protein
PANTHERiPTHR21207 PTHR21207, 1 hit
PfamiView protein in Pfam
PF10274 ParcG, 1 hit
SUPFAMiSSF48371 SSF48371, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

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ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

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MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiPACRL_HUMAN
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q8N7B6
Secondary accession number(s): B2RDB9
, B4DFF8, B4DMN7, Q8TBA8
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: February 20, 2007
Last sequence update: February 20, 2007
Last modified: May 8, 2019
This is version 116 of the entry and version 2 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Human chromosome 4
    Human chromosome 4: entries, gene names and cross-references to MIM
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