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Protein
Submitted name:

Alpha 2,3-sialyltransferase IV type A2+18

Gene
N/A
Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionGlycosyltransferaseSAAS annotationImported, Transferase

Protein family/group databases

CAZyiGT29 Glycosyltransferase Family 29

Names & Taxonomyi

Protein namesi
Submitted name:
Alpha 2,3-sialyltransferase IV type A2+18Imported (EC:2.4.99.4Imported)
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Golgi apparatusSAAS annotation, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 15Sequence analysisAdd BLAST15
ChainiPRO_501258774016 – 328Sequence analysisAdd BLAST313

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Disulfide bondi115 ↔ 268UniRule annotation

Family & Domainsi

Sequence similaritiesi

Belongs to the glycosyltransferase 29 family.SAAS annotation

Keywords - Domaini

SignalSequence analysis, Transmembrane, Transmembrane helixSAAS annotation

Phylogenomic databases

eggNOGiKOG2692 Eukaryota
ENOG410XT8P LUCA
HOVERGENiHBG056676

Family and domain databases

Gene3Di3.90.1480.20, 1 hit
InterProiView protein in InterPro
IPR001675 Glyco_trans_29
IPR038578 GT29-like_sf
IPR012163 Sialyl_trans
PfamiView protein in Pfam
PF00777 Glyco_transf_29, 1 hit
PIRSFiPIRSF005557 Sialyl_trans, 1 hit

Sequencei

Sequence statusi: Complete.

Q8N6A7-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MLALVLVVMV WYSISREDRY IELFYFPIPE KKEPCLQGEA ESKASKLFGK
60 70 80 90 100
LSPLCSYSRD QPIFLRLEDY FWVKTPSAYE LPYGTKGSED LLLRVLAITS
110 120 130 140 150
SSIPKNIQSL RCRRCVVVGN GHRLRNSSLG DAINKYDVVI RLNNAPVAGY
160 170 180 190 200
EGDVGSKTTM RLFYPESAHF DPKVENNPDT LLVLVAFKAM DFHWIETILS
210 220 230 240 250
DKKRVRKGFW KQPPLIWDVN PKQIRILNPF FMEIAADKLL SLPMQQPRKI
260 270 280 290 300
KQKPTTGLLA ITLALHLCDL VHIAGFGYPD AYNKKQTIHY YEQITLKSMA
310 320
GSGHNVSQEA LAIKRMLEMG AIKNLTSF
Length:328
Mass (Da):37,360
Last modified:October 1, 2002 - v1
Checksum:i088F9C7CB365A0C4
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF516602 mRNA Translation: AAM66431.1
UniGeneiHs.591947

Similar proteinsi

Entry informationi

Entry nameiQ8N6A7_HUMAN
AccessioniPrimary (citable) accession number: Q8N6A7
Entry historyiIntegrated into UniProtKB/TrEMBL: October 1, 2002
Last sequence update: October 1, 2002
Last modified: March 28, 2018
This is version 66 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

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