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Entry version 109 (16 Oct 2019)
Sequence version 1 (01 Oct 2002)
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Protein

Myc target protein 1

Gene

MYCT1

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:3 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

May regulate certain MYC target genes, MYC seems to be a direct upstream transcriptional activator. Does not seem to significantly affect growth cell capacity. Overexpression seems to mediate many of the known phenotypic features associated with MYC, including promotion of apoptosis, alteration of morphology, enhancement of anchorage-independent growth, tumorigenic conversion, promotion of genomic instability, and inhibition of hematopoietic differentiation (By similarity).By similarity

Caution

It is uncertain whether Met-1 or Met-49 is the initiator.Curated

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Myc target protein 1
Alternative name(s):
Myc target in myeloid cells protein 1
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:MYCT1
Synonyms:MTLC, MTMC1
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 6

Organism-specific databases

Human Gene Nomenclature Database

More...
HGNCi
HGNC:23172 MYCT1

neXtProt; the human protein knowledge platform

More...
neXtProti
NX_Q8N699

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Cellular componenti

Nucleus

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

DisGeNET

More...
DisGeNETi
80177

Open Targets

More...
OpenTargetsi
ENSG00000120279

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...
PharmGKBi
PA134908917

Miscellaneous databases

Pharos NIH Druggable Genome Knowledgebase

More...
Pharosi
Q8N699

Polymorphism and mutation databases

BioMuta curated single-nucleotide variation and disease association database

More...
BioMutai
MYCT1

Domain mapping of disease mutations (DMDM)

More...
DMDMi
74751049

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00003109591 – 235Myc target protein 1Add BLAST235

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei135PhosphoserineBy similarity1
Modified residuei138PhosphoserineBy similarity1
Modified residuei141PhosphoserineBy similarity1
Modified residuei149PhosphoserineBy similarity1

Keywords - PTMi

Phosphoprotein

Proteomic databases

jPOST - Japan Proteome Standard Repository/Database

More...
jPOSTi
Q8N699

MassIVE - Mass Spectrometry Interactive Virtual Environment

More...
MassIVEi
Q8N699

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q8N699

PeptideAtlas

More...
PeptideAtlasi
Q8N699

PRoteomics IDEntifications database

More...
PRIDEi
Q8N699

ProteomicsDB: a multi-organism proteome resource

More...
ProteomicsDBi
72150

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
Q8N699

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
Q8N699

SwissPalm database of S-palmitoylation events

More...
SwissPalmi
Q8N699

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

<p>This subsection of the ‘Expression’ section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms. By default, the information is derived from experiments at the mRNA level, unless specified ‘at protein level’. <br></br>Examples: <a href="http://www.uniprot.org/uniprot/P92958#expression">P92958</a>, <a href="http://www.uniprot.org/uniprot/Q8TDN4#expression">Q8TDN4</a>, <a href="http://www.uniprot.org/uniprot/O14734#expression">O14734</a><p><a href='/help/tissue_specificity' target='_top'>More...</a></p>Tissue specificityi

Down-regulated in gastric cancer tissues.

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSG00000120279 Expressed in 191 organ(s), highest expression level in upper lobe of lung

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
Q8N699 baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
Q8N699 HS

Organism-specific databases

Human Protein Atlas

More...
HPAi
HPA047992

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGrid)

More...
BioGridi
123159, 2 interactors

Protein interaction database and analysis system

More...
IntActi
Q8N699, 3 interactors

Molecular INTeraction database

More...
MINTi
Q8N699

STRING: functional protein association networks

More...
STRINGi
9606.ENSP00000356214

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Motif

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes a short (usually not more than 20 amino acids) conserved sequence motif of biological significance.<p><a href='/help/motif' target='_top'>More...</a></p>Motifi95 – 113Bipartite nuclear localization signalSequence analysisAdd BLAST19

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the MYCT1 family.Curated

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
ENOG410IE0H Eukaryota
ENOG4111XBR LUCA

Ensembl GeneTree

More...
GeneTreei
ENSGT00390000011642

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
HOG000113704

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q8N699

Identification of Orthologs from Complete Genome Data

More...
OMAi
ENFWEDL

Database of Orthologous Groups

More...
OrthoDBi
1364750at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q8N699

TreeFam database of animal gene trees

More...
TreeFami
TF333196

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR029180 Myc_target_1

The PANTHER Classification System

More...
PANTHERi
PTHR14869 PTHR14869, 1 hit

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF15179 Myc_target_1, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry has 1 described isoform and 2 potential isoforms that are computationally mapped.Show allAlign All

Q8N699-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MRTQVYEGLC KNYFSLAVLQ RDRIKLLFFD ILVFLSVFLL FLLFLVDIMA
60 70 80 90 100
NNTTSLGSPW PENFWEDLIM SFTVSMAIGL VLGGFIWAVF ICLSRRRRAS
110 120 130 140 150
APISQWSSSR RSRSSYTHGL NRTGFYRHSG CERRSNLSLA SLTFQRQASL
160 170 180 190 200
EQANSFPRKS SFRASTFHPF LQCPPLPVET ESQLVTLPSS NISPTISTSH
210 220 230
SLSRPDYWSS NSLRVGLSTP PPPAYESIIK AFPDS
Length:235
Mass (Da):26,593
Last modified:October 1, 2002 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i880ADD4C9598F53F
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 2 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
E9PQ55E9PQ55_HUMAN
Myc target protein 1
MYCT1
67Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
H0YDV5H0YDV5_HUMAN
Myc target protein 1
MYCT1
216Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti147Q → R in BAB15035 (PubMed:14702039).Curated1

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section describes natural variant(s) of the protein sequence.<p><a href='/help/variant' target='_top'>More...</a></p>Natural variantiVAR_037115119G → S. Corresponds to variant dbSNP:rs17710008Ensembl.1
Natural variantiVAR_037116127R → G1 PublicationCorresponds to variant dbSNP:rs17852097Ensembl.1

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AF527367 mRNA Translation: AAM88866.1
AK024922 mRNA Translation: BAB15035.1
AL390960 Genomic DNA No translation available.
CH471051 Genomic DNA Translation: EAW47726.1
BC022556 mRNA Translation: AAH22556.2
BC128463 mRNA Translation: AAI28464.1
BC128464 mRNA Translation: AAI28465.1
AL834500 mRNA Translation: CAD39158.3

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS5239.1

NCBI Reference Sequences

More...
RefSeqi
NP_079383.2, NM_025107.2
XP_011534451.1, XM_011536149.2
XP_011534452.1, XM_011536150.2
XP_011534453.1, XM_011536151.2
XP_011534454.1, XM_011536152.2
XP_016866808.1, XM_017011319.1

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENST00000367245; ENSP00000356214; ENSG00000120279

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
80177

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
hsa:80177

UCSC genome browser

More...
UCSCi
uc003qpc.5 human

Keywords - Coding sequence diversityi

Polymorphism

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF527367 mRNA Translation: AAM88866.1
AK024922 mRNA Translation: BAB15035.1
AL390960 Genomic DNA No translation available.
CH471051 Genomic DNA Translation: EAW47726.1
BC022556 mRNA Translation: AAH22556.2
BC128463 mRNA Translation: AAI28464.1
BC128464 mRNA Translation: AAI28465.1
AL834500 mRNA Translation: CAD39158.3
CCDSiCCDS5239.1
RefSeqiNP_079383.2, NM_025107.2
XP_011534451.1, XM_011536149.2
XP_011534452.1, XM_011536150.2
XP_011534453.1, XM_011536151.2
XP_011534454.1, XM_011536152.2
XP_016866808.1, XM_017011319.1

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

Protein-protein interaction databases

BioGridi123159, 2 interactors
IntActiQ8N699, 3 interactors
MINTiQ8N699
STRINGi9606.ENSP00000356214

PTM databases

iPTMnetiQ8N699
PhosphoSitePlusiQ8N699
SwissPalmiQ8N699

Polymorphism and mutation databases

BioMutaiMYCT1
DMDMi74751049

Proteomic databases

jPOSTiQ8N699
MassIVEiQ8N699
PaxDbiQ8N699
PeptideAtlasiQ8N699
PRIDEiQ8N699
ProteomicsDBi72150

Genome annotation databases

EnsembliENST00000367245; ENSP00000356214; ENSG00000120279
GeneIDi80177
KEGGihsa:80177
UCSCiuc003qpc.5 human

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
80177
DisGeNETi80177

GeneCards: human genes, protein and diseases

More...
GeneCardsi
MYCT1
HGNCiHGNC:23172 MYCT1
HPAiHPA047992
neXtProtiNX_Q8N699
OpenTargetsiENSG00000120279
PharmGKBiPA134908917

GenAtlas: human gene database

More...
GenAtlasi
Search...

Phylogenomic databases

eggNOGiENOG410IE0H Eukaryota
ENOG4111XBR LUCA
GeneTreeiENSGT00390000011642
HOGENOMiHOG000113704
InParanoidiQ8N699
OMAiENFWEDL
OrthoDBi1364750at2759
PhylomeDBiQ8N699
TreeFamiTF333196

Miscellaneous databases

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...
ChiTaRSi
MYCT1 human

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...
GenomeRNAii
80177
PharosiQ8N699

Protein Ontology

More...
PROi
PR:Q8N699

Gene expression databases

BgeeiENSG00000120279 Expressed in 191 organ(s), highest expression level in upper lobe of lung
ExpressionAtlasiQ8N699 baseline and differential
GenevisibleiQ8N699 HS

Family and domain databases

InterProiView protein in InterPro
IPR029180 Myc_target_1
PANTHERiPTHR14869 PTHR14869, 1 hit
PfamiView protein in Pfam
PF15179 Myc_target_1, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiMYCT1_HUMAN
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q8N699
Secondary accession number(s): Q8N396, Q8TBE8, Q9H763
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: November 13, 2007
Last sequence update: October 1, 2002
Last modified: October 16, 2019
This is version 109 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Human chromosome 6
    Human chromosome 6: entries, gene names and cross-references to MIM
  2. SIMILARITY comments
    Index of protein domains and families
  3. Human polymorphisms and disease mutations
    Index of human polymorphisms and disease mutations
  4. Human entries with polymorphisms or disease mutations
    List of human entries with polymorphisms or disease mutations
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