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Entry version 123 (12 Aug 2020)
Sequence version 3 (07 Jul 2009)
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Protein

FTS and Hook-interacting protein

Gene

FAM160A2

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Component of the FTS/Hook/FHIP complex (FHF complex). The FHF complex may function to promote vesicle trafficking and/or fusion via the homotypic vesicular protein sorting complex (the HOPS complex).1 Publication

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Biological processProtein transport, Transport

Enzyme and pathway databases

Pathway Commons web resource for biological pathway data

More...
PathwayCommonsi
Q8N612

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
FTS and Hook-interacting protein
Short name:
FHIP
Alternative name(s):
Protein FAM160A2
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:FAM160A2
Synonyms:C11orf56, KIAA1759
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 11

Organism-specific databases

Eukaryotic Pathogen Database Resources

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EuPathDBi
HostDB:ENSG00000051009.10

Human Gene Nomenclature Database

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HGNCi
HGNC:25378, FAM160A2

neXtProt; the human protein knowledge platform

More...
neXtProti
NX_Q8N612

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

DisGeNET

More...
DisGeNETi
84067

Open Targets

More...
OpenTargetsi
ENSG00000051009

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...
PharmGKBi
PA162386769

Miscellaneous databases

Pharos NIH Druggable Genome Knowledgebase

More...
Pharosi
Q8N612, Tbio

Polymorphism and mutation databases

BioMuta curated single-nucleotide variation and disease association database

More...
BioMutai
FAM160A2

Domain mapping of disease mutations (DMDM)

More...
DMDMi
251757473

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00002538591 – 972FTS and Hook-interacting proteinAdd BLAST972

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei467PhosphoserineCombined sources1
Modified residuei510PhosphoserineBy similarity1
Modified residuei523PhosphoserineBy similarity1
Modified residuei529PhosphoserineBy similarity1
Modified residuei533PhosphoserineBy similarity1
Modified residuei859PhosphoserineCombined sources1
Modified residuei897PhosphoserineCombined sources1

Keywords - PTMi

Phosphoprotein

Proteomic databases

Encyclopedia of Proteome Dynamics

More...
EPDi
Q8N612

jPOST - Japan Proteome Standard Repository/Database

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jPOSTi
Q8N612

MassIVE - Mass Spectrometry Interactive Virtual Environment

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MassIVEi
Q8N612

MaxQB - The MaxQuant DataBase

More...
MaxQBi
Q8N612

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q8N612

PeptideAtlas

More...
PeptideAtlasi
Q8N612

PRoteomics IDEntifications database

More...
PRIDEi
Q8N612

ProteomicsDB: a multi-organism proteome resource

More...
ProteomicsDBi
72122 [Q8N612-1]
72123 [Q8N612-2]
72124 [Q8N612-3]

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
Q8N612

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
Q8N612

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSG00000051009, Expressed in transverse colon and 204 other tissues

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
Q8N612, baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
Q8N612, HS

Organism-specific databases

Human Protein Atlas

More...
HPAi
ENSG00000051009, Low tissue specificity

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction%5Fsection">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function%5Fsection">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

Component of the FTS/Hook/FHIP complex (FHF complex), composed of AKTIP/FTS, FAM160A2, and one or more members of the Hook family of proteins HOOK1, HOOK2, and HOOK3. The FHF complex associates with the homotypic vesicular sorting complex (the HOPS complex).

1 Publication

<p>This subsection of the '<a href="http://www.uniprot.org/help/interaction%5Fsection">Interaction</a>' section provides information about binary protein-protein interactions. The data presented in this section are a quality-filtered subset of binary interactions automatically derived from the <a href="https://www.ebi.ac.uk/intact/">IntAct database</a>. It is updated at every <a href="http://www.uniprot.org/help/synchronization">UniProt release</a>.<p><a href='/help/binary_interactions' target='_top'>More...</a></p>Binary interactionsi

Hide details

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGRID)

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BioGRIDi
123862, 11 interactors

CORUM comprehensive resource of mammalian protein complexes

More...
CORUMi
Q8N612

Protein interaction database and analysis system

More...
IntActi
Q8N612, 9 interactors

STRING: functional protein association networks

More...
STRINGi
9606.ENSP00000265978

Miscellaneous databases

RNAct, Protein-RNA interaction predictions for model organisms.

More...
RNActi
Q8N612, protein

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
Q8N612

Database of comparative protein structure models

More...
ModBasei
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the UPF0518 family.Curated

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG3695, Eukaryota

Ensembl GeneTree

More...
GeneTreei
ENSGT00950000182936

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
CLU_007807_1_0_1

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q8N612

Identification of Orthologs from Complete Genome Data

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OMAi
RIAQCQR

Database of Orthologous Groups

More...
OrthoDBi
141539at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q8N612

TreeFam database of animal gene trees

More...
TreeFami
TF313941

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR019384, RetinoicA-induced_16-like

The PANTHER Classification System

More...
PANTHERi
PTHR21705, PTHR21705, 1 hit

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF10257, RAI16-like, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequences (3+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry describes 3 <p>This subsection of the 'Sequence' section lists the alternative protein sequences (isoforms) that can be generated from the same gene by a single or by the combination of up to four biological events (alternative promoter usage, alternative splicing, alternative initiation and ribosomal frameshifting). Additionally, this section gives relevant information on each alternative protein isoform. This section is only present in reviewed entries, i.e. in UniProtKB/Swiss-Prot.<p><a href='/help/alternative_products' target='_top'>More...</a></p> isoformsi produced by alternative splicing. AlignAdd to basket

This entry has 3 described isoforms and 1 potential isoform that is computationally mapped.Show allAlign All

Isoform 1 (identifier: Q8N612-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the <div> <p><b>What is the canonical sequence?</b><p><a href='/help/canonical_and_isoforms' target='_top'>More...</a></p>canonicali sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide
        10         20         30         40         50
MERMNWLSRL ASRGPGHRIP QGANLQTPVM ADPETCLMVF KNHWSQVVRI
60 70 80 90 100
LERQGPRAAP GGADDLSAVR NHTYQMLTLL AEDRAVPSAP TGPGPLLEFA
110 120 130 140 150
LHEDLLTRVL TWQLQWDELG DGVEERRAEQ LKLFEMLVSE ARQPLLRHGP
160 170 180 190 200
VREALLTLLD ACGRPVPSSP ALDEGLVLLL SQLCVCVAQE PSLLEFFLQP
210 220 230 240 250
PPEPGAAPRL LLFSRLVPFV HREGTLGQQA RDALLLLMAL SAGSPTVGRY
260 270 280 290 300
IADHSYFCPV LATGLSALYS SLPRKIEVPG DDWHCLRRED WLGVPALALF
310 320 330 340 350
MSSLEFCNAV IQVAHPLVQK QLVDYIHNGF LVPVMGPALH KTSVEEMIAS
360 370 380 390 400
TAYLELFLRS ISEPALLRTF LRFLLLHRHD THTILDTLVA RIGSNSRLCM
410 420 430 440 450
VSLSLFRTLL NLSCEDVLLQ LVLRYLVPCN HVMLSQKPAV RDVDLYGRAA
460 470 480 490 500
DKFLSLIPRC CRHHAPSPPR PEHASWARGP GSPSVDSSSV TTVPRPSTPS
510 520 530 540 550
RLALFLRQQS LGGSESPGPA PCSPGLSASP ASSPGRRPTP AEEPGELEDN
560 570 580 590 600
YLEYLREARR GVDRCVRACR TWSAPYDGER PSPEPSPFGS RTKKRSLLPE
610 620 630 640 650
EDRNNVGEGE EEELGRRGRA GGAGEGPGHL PPPQLNGVPG SWPEGAKKVR
660 670 680 690 700
LVPKEGAGEL LEGISEGMAG LEGFGQELRE LEVALSNGGT GSESPLEPPL
710 720 730 740 750
PLEEEEAYES FTCPPEPPGP FLSSPLRTLN QLPSQPFTGP FMAVLFAKLE
760 770 780 790 800
NMLQNSVYVN FLLTGLVAQL ACHPQPLLRS FLLNTNMVFQ PSVKSLLQVL
810 820 830 840 850
GSVKNKIENF AASQEDFPAL LSKAKKYLIA RGKLDWAEGP AAGPAPRRSD
860 870 880 890 900
PLVKSRRPSL GELLLRHAHS PTRARQAAQL VLQPGRDGAG LGLSGGSPGA
910 920 930 940 950
STPVLLTRGG APERQGEALR VKNAVYCAVI FPEFLKELAA ISQAHAVTSP
960 970
FLLETSEEGS GPLISGCGPL NP
Length:972
Mass (Da):105,568
Last modified:July 7, 2009 - v3
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iF1CC45667E1B6811
GO
Isoform 2 (identifier: Q8N612-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     479-479: G → GGPSRETGRREDITG

Show »
Length:986
Mass (Da):107,081
Checksum:i18C2DACC61A49115
GO
Isoform 3 (identifier: Q8N612-3) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     1-75: Missing.
     757-780: VYVNFLLTGLVAQLACHPQPLLRS → ALSCSTPTWSSSPVSSPCCRCWAL
     781-972: Missing.

Show »
Length:705
Mass (Da):76,834
Checksum:iA1F02608EBBE8B11
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There is 1 potential isoform mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
E9PJK5E9PJK5_HUMAN
FTS and Hook-interacting protein
FAM160A2
838Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

<p>This subsection of the 'Sequence' section reports difference(s) between the protein sequence shown in the UniProtKB entry and other available protein sequences derived from the same gene.<p><a href='/help/sequence_caution' target='_top'>More...</a></p>Sequence cautioni

The sequence BAB21850 differs from that shown. Reason: Erroneous initiation.Curated

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti95P → S in CAB66657 (PubMed:11230166).Curated1
Sequence conflicti136M → V in CAB66657 (PubMed:11230166).Curated1
Sequence conflicti186C → Y in BAB15443 (PubMed:14702039).Curated1
Sequence conflicti503A → V in CAB66657 (PubMed:11230166).Curated1

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section describes natural variant(s) of the protein sequence.<p><a href='/help/variant' target='_top'>More...</a></p>Natural variantiVAR_057805462R → W. Corresponds to variant dbSNP:rs35932378Ensembl.1
Natural variantiVAR_028739491T → M2 PublicationsCorresponds to variant dbSNP:rs3750944Ensembl.1
Natural variantiVAR_028740619R → L. Corresponds to variant dbSNP:rs3750943Ensembl.1
Natural variantiVAR_028741754Q → H. Corresponds to variant dbSNP:rs11040808Ensembl.1

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section describes the sequence of naturally occurring alternative protein isoform(s). The changes in the amino acid sequence may be due to alternative splicing, alternative promoter usage, alternative initiation, or ribosomal frameshifting.<p><a href='/help/var_seq' target='_top'>More...</a></p>Alternative sequenceiVSP_0211281 – 75Missing in isoform 3. 1 PublicationAdd BLAST75
Alternative sequenceiVSP_021129479G → GGPSRETGRREDITG in isoform 2. 1 Publication1
Alternative sequenceiVSP_021130757 – 780VYVNF…PLLRS → ALSCSTPTWSSSPVSSPCCR CWAL in isoform 3. 1 PublicationAdd BLAST24
Alternative sequenceiVSP_021131781 – 972Missing in isoform 3. 1 PublicationAdd BLAST192

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AB051546 mRNA Translation: BAB21850.1 Different initiation.
AK026318 mRNA Translation: BAB15443.1
AL136723 mRNA Translation: CAB66657.1
BC030825 mRNA Translation: AAH30825.1

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS44530.1 [Q8N612-1]
CCDS7760.1 [Q8N612-2]

NCBI Reference Sequences

More...
RefSeqi
NP_001092264.1, NM_001098794.1 [Q8N612-1]
NP_115503.2, NM_032127.3 [Q8N612-2]
XP_006718406.1, XM_006718343.2 [Q8N612-2]
XP_011518699.1, XM_011520397.2 [Q8N612-2]

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENST00000265978; ENSP00000265978; ENSG00000051009 [Q8N612-2]
ENST00000449352; ENSP00000416918; ENSG00000051009 [Q8N612-1]

Database of genes from NCBI RefSeq genomes

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GeneIDi
84067

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
hsa:84067

UCSC genome browser

More...
UCSCi
uc001mck.5, human [Q8N612-1]

Keywords - Coding sequence diversityi

Alternative splicing, Polymorphism

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB051546 mRNA Translation: BAB21850.1 Different initiation.
AK026318 mRNA Translation: BAB15443.1
AL136723 mRNA Translation: CAB66657.1
BC030825 mRNA Translation: AAH30825.1
CCDSiCCDS44530.1 [Q8N612-1]
CCDS7760.1 [Q8N612-2]
RefSeqiNP_001092264.1, NM_001098794.1 [Q8N612-1]
NP_115503.2, NM_032127.3 [Q8N612-2]
XP_006718406.1, XM_006718343.2 [Q8N612-2]
XP_011518699.1, XM_011520397.2 [Q8N612-2]

3D structure databases

SMRiQ8N612
ModBaseiSearch...

Protein-protein interaction databases

BioGRIDi123862, 11 interactors
CORUMiQ8N612
IntActiQ8N612, 9 interactors
STRINGi9606.ENSP00000265978

PTM databases

iPTMnetiQ8N612
PhosphoSitePlusiQ8N612

Polymorphism and mutation databases

BioMutaiFAM160A2
DMDMi251757473

Proteomic databases

EPDiQ8N612
jPOSTiQ8N612
MassIVEiQ8N612
MaxQBiQ8N612
PaxDbiQ8N612
PeptideAtlasiQ8N612
PRIDEiQ8N612
ProteomicsDBi72122 [Q8N612-1]
72123 [Q8N612-2]
72124 [Q8N612-3]

Protocols and materials databases

Antibodypedia a portal for validated antibodies

More...
Antibodypediai
67203, 45 antibodies

The DNASU plasmid repository

More...
DNASUi
84067

Genome annotation databases

EnsembliENST00000265978; ENSP00000265978; ENSG00000051009 [Q8N612-2]
ENST00000449352; ENSP00000416918; ENSG00000051009 [Q8N612-1]
GeneIDi84067
KEGGihsa:84067
UCSCiuc001mck.5, human [Q8N612-1]

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
84067
DisGeNETi84067
EuPathDBiHostDB:ENSG00000051009.10

GeneCards: human genes, protein and diseases

More...
GeneCardsi
FAM160A2
HGNCiHGNC:25378, FAM160A2
HPAiENSG00000051009, Low tissue specificity
neXtProtiNX_Q8N612
OpenTargetsiENSG00000051009
PharmGKBiPA162386769

Human Unidentified Gene-Encoded large proteins database

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HUGEi
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GenAtlas: human gene database

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GenAtlasi
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Phylogenomic databases

eggNOGiKOG3695, Eukaryota
GeneTreeiENSGT00950000182936
HOGENOMiCLU_007807_1_0_1
InParanoidiQ8N612
OMAiRIAQCQR
OrthoDBi141539at2759
PhylomeDBiQ8N612
TreeFamiTF313941

Enzyme and pathway databases

PathwayCommonsiQ8N612

Miscellaneous databases

BioGRID ORCS database of CRISPR phenotype screens

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BioGRID-ORCSi
84067, 3 hits in 873 CRISPR screens

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

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ChiTaRSi
FAM160A2, human

The Gene Wiki collection of pages on human genes and proteins

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GeneWikii
C11orf56

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

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GenomeRNAii
84067
PharosiQ8N612, Tbio

Protein Ontology

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PROi
PR:Q8N612
RNActiQ8N612, protein

Gene expression databases

BgeeiENSG00000051009, Expressed in transverse colon and 204 other tissues
ExpressionAtlasiQ8N612, baseline and differential
GenevisibleiQ8N612, HS

Family and domain databases

InterProiView protein in InterPro
IPR019384, RetinoicA-induced_16-like
PANTHERiPTHR21705, PTHR21705, 1 hit
PfamiView protein in Pfam
PF10257, RAI16-like, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

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ProtoNeti
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MobiDB: a database of protein disorder and mobility annotations

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MobiDBi
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<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiF16A2_HUMAN
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q8N612
Secondary accession number(s): Q9C0A4, Q9H0N3, Q9H624
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: October 17, 2006
Last sequence update: July 7, 2009
Last modified: August 12, 2020
This is version 123 of the entry and version 3 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. Uncharacterized protein families (UPF)
    List of uncharacterized protein family (UPF) entries
  2. Human chromosome 11
    Human chromosome 11: entries, gene names and cross-references to MIM
  3. Human polymorphisms and disease mutations
    Index of human polymorphisms and disease mutations
  4. SIMILARITY comments
    Index of protein domains and families
  5. Human entries with polymorphisms or disease mutations
    List of human entries with polymorphisms or disease mutations
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