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Entry version 138 (07 Apr 2021)
Sequence version 2 (26 Feb 2008)
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Protein

Mitochondrial carrier protein SCaMC-3L

Gene

SLC25A41

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:4 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at transcript leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Calcium-independent ATP-Mg/Pi exchanger that catalyzes the electroneutral exchange of Mg-ATP or free ADP against an hydrogenphosphate and participates in the net transport of adenine nucleotides across the mitochondria inner membrane.By similarity

<p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">Function</a> section describes the catalytic activity of an enzyme, i.e. a chemical reaction that the enzyme catalyzes.<p><a href='/help/catalytic_activity' target='_top'>More...</a></p>Catalytic activityi

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Biological processTransport

Enzyme and pathway databases

Pathway Commons web resource for biological pathway data

More...
PathwayCommonsi
Q8N5S1

Protein family/group databases

Transport Classification Database

More...
TCDBi
2.A.29.23.6, the mitochondrial carrier (mc) family

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Mitochondrial carrier protein SCaMC-3LCurated
Alternative name(s):
Mitochondrial ATP-Mg/Pi carrier protein SLC25A41Curated
Small calcium-binding mitochondrial carrier protein 3-like
Short name:
SCaMC-3-likeBy similarity
Short name:
SCaMC-3LBy similarity
Solute carrier family 25 member 41
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:SLC25A41Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 19

Organism-specific databases

Human Gene Nomenclature Database

More...
HGNCi
HGNC:28533, SLC25A41

Online Mendelian Inheritance in Man (OMIM)

More...
MIMi
610822, gene

neXtProt; the human protein knowledge platform

More...
neXtProti
NX_Q8N5S1

Eukaryotic Pathogen, Vector and Host Database Resources

More...
VEuPathDBi
HostDB:ENSG00000181240.13

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular%5Flocation%5Fsection">'Subcellular location'</a> section describes the extent of a membrane-spanning region of the protein. It denotes the presence of both alpha-helical transmembrane regions and the membrane spanning regions of beta-barrel transmembrane proteins.<p><a href='/help/transmem' target='_top'>More...</a></p>Transmembranei96 – 113Helical; Name=1Sequence analysisAdd BLAST18
Transmembranei151 – 170Helical; Name=2Sequence analysisAdd BLAST20
Transmembranei194 – 207Helical; Name=3Sequence analysisAdd BLAST14
Transmembranei245 – 263Helical; Name=4Sequence analysisAdd BLAST19
Transmembranei282 – 306Helical; Name=5Sequence analysisAdd BLAST25
Transmembranei342 – 361Helical; Name=6Sequence analysisAdd BLAST20

Keywords - Cellular componenti

Membrane, Mitochondrion, Mitochondrion inner membrane

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

DisGeNET

More...
DisGeNETi
284427

Open Targets

More...
OpenTargetsi
ENSG00000181240

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...
PharmGKBi
PA162403684

Miscellaneous databases

Pharos NIH Druggable Genome Knowledgebase

More...
Pharosi
Q8N5S1, Tdark

Genetic variation databases

BioMuta curated single-nucleotide variation and disease association database

More...
BioMutai
SLC25A41

Domain mapping of disease mutations (DMDM)

More...
DMDMi
172046142

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00003199901 – 370Mitochondrial carrier protein SCaMC-3LAdd BLAST370

Proteomic databases

MassIVE - Mass Spectrometry Interactive Virtual Environment

More...
MassIVEi
Q8N5S1

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q8N5S1

PeptideAtlas

More...
PeptideAtlasi
Q8N5S1

PRoteomics IDEntifications database

More...
PRIDEi
Q8N5S1

ProteomicsDB: a multi-organism proteome resource

More...
ProteomicsDBi
72088 [Q8N5S1-1]
72089 [Q8N5S1-2]

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
Q8N5S1

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
Q8N5S1

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSG00000181240, Expressed in cerebellar hemisphere and 103 other tissues

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
Q8N5S1, HS

Organism-specific databases

Human Protein Atlas

More...
HPAi
ENSG00000181240, Group enriched (brain, testis)

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGRID)

More...
BioGRIDi
129873, 90 interactors

Protein interaction database and analysis system

More...
IntActi
Q8N5S1, 63 interactors

STRING: functional protein association networks

More...
STRINGi
9606.ENSP00000322649

Miscellaneous databases

RNAct, Protein-RNA interaction predictions for model organisms.

More...
RNActi
Q8N5S1, protein

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
Q8N5S1

Database of comparative protein structure models

More...
ModBasei
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section indicates the positions and types of repeated sequence motifs or repeated domains within the protein.<p><a href='/help/repeat' target='_top'>More...</a></p>Repeati90 – 176Solcar 1Sequence analysisAdd BLAST87
Repeati184 – 269Solcar 2Sequence analysisAdd BLAST86
Repeati280 – 367Solcar 3Sequence analysisAdd BLAST88

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi30 – 44Pro-richSequence analysisAdd BLAST15

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Keywords - Domaini

Repeat, Transmembrane, Transmembrane helix

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG0036, Eukaryota

Ensembl GeneTree

More...
GeneTreei
ENSGT00940000162419

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
CLU_015166_10_2_1

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q8N5S1

Identification of Orthologs from Complete Genome Data

More...
OMAi
GVHESPP

Database of Orthologous Groups

More...
OrthoDBi
442523at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q8N5S1

TreeFam database of animal gene trees

More...
TreeFami
TF313492

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
1.50.40.10, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR002067, Mit_carrier
IPR018108, Mitochondrial_sb/sol_carrier
IPR023395, Mt_carrier_dom_sf

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF00153, Mito_carr, 3 hits

Protein Motif fingerprint database; a protein domain database

More...
PRINTSi
PR00926, MITOCARRIER

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF103506, SSF103506, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS50920, SOLCAR, 3 hits

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequences (2)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry describes 2 <p>This subsection of the 'Sequence' section lists the alternative protein sequences (isoforms) that can be generated from the same gene by a single or by the combination of up to four biological events (alternative promoter usage, alternative splicing, alternative initiation and ribosomal frameshifting). Additionally, this section gives relevant information on each alternative protein isoform. This section is only present in reviewed entries, i.e. in UniProtKB/Swiss-Prot.<p><a href='/help/alternative_products' target='_top'>More...</a></p> isoformsi produced by alternative splicing. AlignAdd to basket
Isoform 11 Publication (identifier: Q8N5S1-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the <div> <p><b>What is the canonical sequence?</b><p><a href='/help/canonical_and_isoforms' target='_top'>More...</a></p>canonicali sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide
        10         20         30         40         50
MGAQPGEPQN TCSRIQTLFR RVKTLLIKAP PPPQPPPPPP SWNPGCTHVY
60 70 80 90 100
GYAFGHMHDN NLEHLPSQQV LDTGEQLMVP VEVLEVDNKE ALWKFLLSGA
110 120 130 140 150
MAGAVSRTGT APLDRAKVYM QVYSSKTNFT NLLGGLQSMV QEGGFRSLWR
160 170 180 190 200
GNGINVLKIA PEYAIKFSVF EQCKNYFCGI QGSPPFQERL LAGSLAVAIS
210 220 230 240 250
QTLINPMEVL KTRLTLRRTG QYKGLLDCAR QILQREGTRA LYRGYLPNML
260 270 280 290 300
GIIPYACTDL AVYEMLQCFW VKSGRDMGDP SGLVSLSSVT LSTTCGQMAS
310 320 330 340 350
YPLTLVRTRM QAQDTVEGSN PTMRGVLQRI LAQQGWLGLY RGMTPTLLKV
360 370
LPAGGISYVV YEAMKKTLGI
Length:370
Mass (Da):40,795
Last modified:February 26, 2008 - v2
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i818C9FC7CD5F6041
GO
Isoform 21 Publication (identifier: Q8N5S1-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     121-242: QVYSSKTNFT...LQREGTRALY → QLLGRLRQEN...PRPSSTPWRC
     243-370: Missing.

Note: May be produced at very low levels due to a premature stop codon in the mRNA, leading to nonsense-mediated mRNA decay.Curated
Show »
Length:242
Mass (Da):26,397
Checksum:i0C76E27DF28893AE
GO

<p>This subsection of the 'Sequence' section reports difference(s) between the protein sequence shown in the UniProtKB entry and other available protein sequences derived from the same gene.<p><a href='/help/sequence_caution' target='_top'>More...</a></p>Sequence cautioni

The sequence AAH31671 differs from that shown. Reason: Erroneous initiation.Curated
The sequence BAC05163 differs from that shown. Reason: Erroneous translation. Wrong choice of CDS.Curated

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section describes natural variant(s) of the protein sequence.<p><a href='/help/variant' target='_top'>More...</a></p>Natural variantiVAR_050132144G → S. Corresponds to variant dbSNP:rs34488963Ensembl.1
Natural variantiVAR_050133258T → S. Corresponds to variant dbSNP:rs11883242Ensembl.1

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section describes the sequence of naturally occurring alternative protein isoform(s). The changes in the amino acid sequence may be due to alternative splicing, alternative promoter usage, alternative initiation, or ribosomal frameshifting.<p><a href='/help/var_seq' target='_top'>More...</a></p>Alternative sequenceiVSP_052690121 – 242QVYSS…TRALY → QLLGRLRQENRLNLGGGGCS EPRSPDRTPAWATESTPPRR TSPTCWGGYRAWSRRAASAP CGGATASTCSRLLLSMPSSS PYSSSARITSVEYKGPRPSR SVSLLAPWLWPSPRPSSTPW RC in isoform 2. 1 PublicationAdd BLAST122
Alternative sequenceiVSP_035524243 – 370Missing in isoform 2. 1 PublicationAdd BLAST128

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AK097761 mRNA Translation: BAC05163.1 Sequence problems.
AC011539 Genomic DNA No translation available.
CH471139 Genomic DNA Translation: EAW69092.1
CH471139 Genomic DNA Translation: EAW69094.1
CH471139 Genomic DNA Translation: EAW69093.1
BC031671 mRNA Translation: AAH31671.1 Different initiation.

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS45937.1 [Q8N5S1-1]

NCBI Reference Sequences

More...
RefSeqi
NP_001308227.1, NM_001321298.1
NP_775908.2, NM_173637.3 [Q8N5S1-1]

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENST00000321510; ENSP00000322649; ENSG00000181240 [Q8N5S1-1]
ENST00000458275; ENSP00000405411; ENSG00000181240 [Q8N5S1-2]
ENST00000597558; ENSP00000471238; ENSG00000181240 [Q8N5S1-1]

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
284427

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
hsa:284427

UCSC genome browser

More...
UCSCi
uc010dus.4, human [Q8N5S1-1]

Keywords - Coding sequence diversityi

Alternative splicing

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK097761 mRNA Translation: BAC05163.1 Sequence problems.
AC011539 Genomic DNA No translation available.
CH471139 Genomic DNA Translation: EAW69092.1
CH471139 Genomic DNA Translation: EAW69094.1
CH471139 Genomic DNA Translation: EAW69093.1
BC031671 mRNA Translation: AAH31671.1 Different initiation.
CCDSiCCDS45937.1 [Q8N5S1-1]
RefSeqiNP_001308227.1, NM_001321298.1
NP_775908.2, NM_173637.3 [Q8N5S1-1]

3D structure databases

SMRiQ8N5S1
ModBaseiSearch...

Protein-protein interaction databases

BioGRIDi129873, 90 interactors
IntActiQ8N5S1, 63 interactors
STRINGi9606.ENSP00000322649

Protein family/group databases

TCDBi2.A.29.23.6, the mitochondrial carrier (mc) family

PTM databases

iPTMnetiQ8N5S1
PhosphoSitePlusiQ8N5S1

Genetic variation databases

BioMutaiSLC25A41
DMDMi172046142

Proteomic databases

MassIVEiQ8N5S1
PaxDbiQ8N5S1
PeptideAtlasiQ8N5S1
PRIDEiQ8N5S1
ProteomicsDBi72088 [Q8N5S1-1]
72089 [Q8N5S1-2]

Protocols and materials databases

Antibodypedia a portal for validated antibodies

More...
Antibodypediai
49970, 20 antibodies

The DNASU plasmid repository

More...
DNASUi
284427

Genome annotation databases

EnsembliENST00000321510; ENSP00000322649; ENSG00000181240 [Q8N5S1-1]
ENST00000458275; ENSP00000405411; ENSG00000181240 [Q8N5S1-2]
ENST00000597558; ENSP00000471238; ENSG00000181240 [Q8N5S1-1]
GeneIDi284427
KEGGihsa:284427
UCSCiuc010dus.4, human [Q8N5S1-1]

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
284427
DisGeNETi284427

GeneCards: human genes, protein and diseases

More...
GeneCardsi
SLC25A41
HGNCiHGNC:28533, SLC25A41
HPAiENSG00000181240, Group enriched (brain, testis)
MIMi610822, gene
neXtProtiNX_Q8N5S1
OpenTargetsiENSG00000181240
PharmGKBiPA162403684
VEuPathDBiHostDB:ENSG00000181240.13

GenAtlas: human gene database

More...
GenAtlasi
Search...

Phylogenomic databases

eggNOGiKOG0036, Eukaryota
GeneTreeiENSGT00940000162419
HOGENOMiCLU_015166_10_2_1
InParanoidiQ8N5S1
OMAiGVHESPP
OrthoDBi442523at2759
PhylomeDBiQ8N5S1
TreeFamiTF313492

Enzyme and pathway databases

PathwayCommonsiQ8N5S1

Miscellaneous databases

BioGRID ORCS database of CRISPR phenotype screens

More...
BioGRID-ORCSi
284427, 36 hits in 994 CRISPR screens

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...
ChiTaRSi
SLC25A41, human

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...
GenomeRNAii
284427
PharosiQ8N5S1, Tdark

Protein Ontology

More...
PROi
PR:Q8N5S1
RNActiQ8N5S1, protein

The Stanford Online Universal Resource for Clones and ESTs

More...
SOURCEi
Search...

Gene expression databases

BgeeiENSG00000181240, Expressed in cerebellar hemisphere and 103 other tissues
GenevisibleiQ8N5S1, HS

Family and domain databases

Gene3Di1.50.40.10, 1 hit
InterProiView protein in InterPro
IPR002067, Mit_carrier
IPR018108, Mitochondrial_sb/sol_carrier
IPR023395, Mt_carrier_dom_sf
PfamiView protein in Pfam
PF00153, Mito_carr, 3 hits
PRINTSiPR00926, MITOCARRIER
SUPFAMiSSF103506, SSF103506, 1 hit
PROSITEiView protein in PROSITE
PS50920, SOLCAR, 3 hits

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiS2541_HUMAN
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q8N5S1
Secondary accession number(s): A8MQ40, D6W642, Q8N7R4
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: February 26, 2008
Last sequence update: February 26, 2008
Last modified: April 7, 2021
This is version 138 of the entry and version 2 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. Human chromosome 19
    Human chromosome 19: entries, gene names and cross-references to MIM
  2. Human entries with genetic variants
    List of human entries with genetic variants
  3. Human variants curated from literature reports
    Index of human variants curated from literature reports
  4. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
  5. SIMILARITY comments
    Index of protein domains and families
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