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Entry version 129 (16 Oct 2019)
Sequence version 2 (06 Feb 2007)
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Protein

Tetratricopeptide repeat protein 39C

Gene

TTC39C

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:3 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at transcript leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Biological processi

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Tetratricopeptide repeat protein 39C
Short name:
TPR repeat protein 39C
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:TTC39C
Synonyms:C18orf17
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 18

Organism-specific databases

Human Gene Nomenclature Database

More...
HGNCi
HGNC:26595 TTC39C

neXtProt; the human protein knowledge platform

More...
neXtProti
NX_Q8N584

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

Open Targets

More...
OpenTargetsi
ENSG00000168234

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...
PharmGKBi
PA162407262

Miscellaneous databases

Pharos NIH Druggable Genome Knowledgebase

More...
Pharosi
Q8N584

Polymorphism and mutation databases

BioMuta curated single-nucleotide variation and disease association database

More...
BioMutai
TTC39C

Domain mapping of disease mutations (DMDM)

More...
DMDMi
125863935

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00002743521 – 583Tetratricopeptide repeat protein 39CAdd BLAST583

Proteomic databases

Encyclopedia of Proteome Dynamics

More...
EPDi
Q8N584

jPOST - Japan Proteome Standard Repository/Database

More...
jPOSTi
Q8N584

MassIVE - Mass Spectrometry Interactive Virtual Environment

More...
MassIVEi
Q8N584

MaxQB - The MaxQuant DataBase

More...
MaxQBi
Q8N584

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q8N584

PeptideAtlas

More...
PeptideAtlasi
Q8N584

PRoteomics IDEntifications database

More...
PRIDEi
Q8N584

ProteomicsDB: a multi-organism proteome resource

More...
ProteomicsDBi
72019 [Q8N584-1]
72020 [Q8N584-2]

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
Q8N584

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
Q8N584

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSG00000168234 Expressed in 175 organ(s), highest expression level in liver

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
Q8N584 baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
Q8N584 HS

Organism-specific databases

Human Protein Atlas

More...
HPAi
HPA065705
HPA065713

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGrid)

More...
BioGridi
125929, 7 interactors

Protein interaction database and analysis system

More...
IntActi
Q8N584, 1 interactor

STRING: functional protein association networks

More...
STRINGi
9606.ENSP00000323645

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
Q8N584

Database of comparative protein structure models

More...
ModBasei
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section indicates the positions and types of repeated sequence motifs or repeated domains within the protein.<p><a href='/help/repeat' target='_top'>More...</a></p>Repeati315 – 348TPR 1Add BLAST34
Repeati353 – 386TPR 2Add BLAST34
Repeati485 – 518TPR 3Add BLAST34

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi19 – 25Poly-Ala7

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the TTC39 family.Curated

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Domaini

Repeat, TPR repeat

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG3783 Eukaryota
ENOG410XTBZ LUCA

Ensembl GeneTree

More...
GeneTreei
ENSGT00950000182917

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
HOG000007788

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q8N584

Identification of Orthologs from Complete Genome Data

More...
OMAi
FFHRAVK

Database of Orthologous Groups

More...
OrthoDBi
269827at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q8N584

TreeFam database of animal gene trees

More...
TreeFami
TF313761

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR019412 Iml2/TPR_39
IPR011990 TPR-like_helical_dom_sf

The PANTHER Classification System

More...
PANTHERi
PTHR31859 PTHR31859, 1 hit

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF10300 DUF3808, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF48452 SSF48452, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequences (3+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry describes 3 <p>This subsection of the ‘Sequence’ section lists the alternative protein sequences (isoforms) that can be generated from the same gene by a single or by the combination of up to four biological events (alternative promoter usage, alternative splicing, alternative initiation and ribosomal frameshifting). Additionally, this section gives relevant information on each alternative protein isoform.<p><a href='/help/alternative_products' target='_top'>More...</a></p> isoformsi produced by alternative splicing. AlignAdd to basket

This entry has 3 described isoforms and 3 potential isoforms that are computationally mapped.Show allAlign All

Isoform 1 (identifier: Q8N584-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the <div> <p><b>What is the canonical sequence?</b><p><a href='/help/canonical_and_isoforms' target='_top'>More...</a></p>canonicali sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide
        10         20         30         40         50
MAGSEQQRPR RRDDGDSDAA AAAAAPLQDA ELALAGINML LNNGFRESDQ
60 70 80 90 100
LFKQYRNHSP LMSFGASFVS FLNAMMTFEE EKMQLACDDL KTTEKLCESE
110 120 130 140 150
EAGVIETIKN KIKKNVDVRK SAPSMVDRLQ RQIIIADCQV YLAVLSFVKQ
160 170 180 190 200
ELSAYIKGGW ILRKAWKIYN KCYLDINALQ ELYQKKLTEE SLTSDAANDN
210 220 230 240 250
HIVAEGVSEE SLNRLKGAVS FGYGLFHLCI SMVPPNLLKI INLLGFPGDR
260 270 280 290 300
LQGLSSLMYA SESKDMKAPL ATLALLWYHT VVRPFFALDG SDNKAGLDEA
310 320 330 340 350
KEILLKKEAA YPNSSLFMFF KGRIQRLECQ INSALTSFHT ALELAVDQRE
360 370 380 390 400
IQHVCLYEIG WCSMIELNFK DAFDSFERLK NESRWSQCYY AYLTAVCQGA
410 420 430 440 450
TGDVDGAQIV FKEVQKLFKR KNNQIEQFSV KKAERFRKQT PTKALCVLAS
460 470 480 490 500
IEVLYLWKAL PNCSFPNLQR MSQACHEVDD SSVVGLKYLL LGAIHKCLGN
510 520 530 540 550
SEDAVQYFQR AVKDELCRQN NLYVQPYACY ELGCLLLDKP ETVGRGRALL
560 570 580
LQAKEDFSGY DFENRLHVRI HAALASLREL VPQ
Length:583
Mass (Da):65,870
Last modified:February 6, 2007 - v2
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i438BF2F476F533AD
GO
Isoform 2 (identifier: Q8N584-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     1-61: Missing.

Show »
Length:522
Mass (Da):59,217
Checksum:i24344A674155D963
GO
Isoform 3 (identifier: Q8N584-3) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     57-76: NHSPLMSFGASFVSFLNAMM → KSFLTSEKTSALPGETQRRL
     77-583: Missing.

Note: No experimental confirmation available.
Show »
Length:76
Mass (Da):8,353
Checksum:i063CA2A2C5167C08
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 3 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
G3V1P2G3V1P2_HUMAN
Chromosome 18 open reading frame 17...
TTC39C C18orf17, hCG_38321
276Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
J3QKX7J3QKX7_HUMAN
Tetratricopeptide repeat protein 39...
TTC39C
67Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
J3QLL8J3QLL8_HUMAN
Tetratricopeptide repeat protein 39...
TTC39C
43Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

<p>This subsection of the ‘Sequence’ section reports difference(s) between the protein sequence shown in the UniProtKB entry and other available protein sequences derived from the same gene.<p><a href='/help/sequence_caution' target='_top'>More...</a></p>Sequence cautioni

The sequence AAH32684 differs from that shown. Reason: Erroneous initiation.Curated

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti210E → G in BAC03578 (PubMed:14702039).Curated1
Sequence conflicti262E → V in BAC03578 (PubMed:14702039).Curated1

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section describes the sequence of naturally occurring alternative protein isoform(s). The changes in the amino acid sequence may be due to alternative splicing, alternative promoter usage, alternative initiation, or ribosomal frameshifting.<p><a href='/help/var_seq' target='_top'>More...</a></p>Alternative sequenceiVSP_0227201 – 61Missing in isoform 2. 2 PublicationsAdd BLAST61
Alternative sequenceiVSP_04603957 – 76NHSPL…LNAMM → KSFLTSEKTSALPGETQRRL in isoform 3. 1 PublicationAdd BLAST20
Alternative sequenceiVSP_04604077 – 583Missing in isoform 3. 1 PublicationAdd BLAST507

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AK091080 mRNA Translation: BAC03578.1
AC010754 Genomic DNA No translation available.
AC090772 Genomic DNA No translation available.
BC016833 mRNA No translation available.
BC032684 mRNA Translation: AAH32684.1 Different initiation.
BC121034 mRNA Translation: AAI21035.1
BC121035 mRNA Translation: AAI21036.1

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS32804.1 [Q8N584-2]
CCDS45839.1 [Q8N584-1]
CCDS58616.1 [Q8N584-3]

NCBI Reference Sequences

More...
RefSeqi
NP_001129465.1, NM_001135993.1 [Q8N584-1]
NP_001230354.1, NM_001243425.1 [Q8N584-3]
NP_001278959.1, NM_001292030.1
NP_694943.2, NM_153211.3 [Q8N584-2]
XP_005258255.1, XM_005258198.4 [Q8N584-2]
XP_016881039.1, XM_017025550.1 [Q8N584-2]

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENST00000304621; ENSP00000306598; ENSG00000168234 [Q8N584-2]
ENST00000317571; ENSP00000323645; ENSG00000168234 [Q8N584-1]
ENST00000584250; ENSP00000464344; ENSG00000168234 [Q8N584-3]

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
125488

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
hsa:125488

UCSC genome browser

More...
UCSCi
uc002kuu.4 human [Q8N584-1]

Keywords - Coding sequence diversityi

Alternative splicing

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK091080 mRNA Translation: BAC03578.1
AC010754 Genomic DNA No translation available.
AC090772 Genomic DNA No translation available.
BC016833 mRNA No translation available.
BC032684 mRNA Translation: AAH32684.1 Different initiation.
BC121034 mRNA Translation: AAI21035.1
BC121035 mRNA Translation: AAI21036.1
CCDSiCCDS32804.1 [Q8N584-2]
CCDS45839.1 [Q8N584-1]
CCDS58616.1 [Q8N584-3]
RefSeqiNP_001129465.1, NM_001135993.1 [Q8N584-1]
NP_001230354.1, NM_001243425.1 [Q8N584-3]
NP_001278959.1, NM_001292030.1
NP_694943.2, NM_153211.3 [Q8N584-2]
XP_005258255.1, XM_005258198.4 [Q8N584-2]
XP_016881039.1, XM_017025550.1 [Q8N584-2]

3D structure databases

SMRiQ8N584
ModBaseiSearch...

Protein-protein interaction databases

BioGridi125929, 7 interactors
IntActiQ8N584, 1 interactor
STRINGi9606.ENSP00000323645

PTM databases

iPTMnetiQ8N584
PhosphoSitePlusiQ8N584

Polymorphism and mutation databases

BioMutaiTTC39C
DMDMi125863935

Proteomic databases

EPDiQ8N584
jPOSTiQ8N584
MassIVEiQ8N584
MaxQBiQ8N584
PaxDbiQ8N584
PeptideAtlasiQ8N584
PRIDEiQ8N584
ProteomicsDBi72019 [Q8N584-1]
72020 [Q8N584-2]

Genome annotation databases

EnsembliENST00000304621; ENSP00000306598; ENSG00000168234 [Q8N584-2]
ENST00000317571; ENSP00000323645; ENSG00000168234 [Q8N584-1]
ENST00000584250; ENSP00000464344; ENSG00000168234 [Q8N584-3]
GeneIDi125488
KEGGihsa:125488
UCSCiuc002kuu.4 human [Q8N584-1]

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
125488

GeneCards: human genes, protein and diseases

More...
GeneCardsi
TTC39C
HGNCiHGNC:26595 TTC39C
HPAiHPA065705
HPA065713
neXtProtiNX_Q8N584
OpenTargetsiENSG00000168234
PharmGKBiPA162407262

GenAtlas: human gene database

More...
GenAtlasi
Search...

Phylogenomic databases

eggNOGiKOG3783 Eukaryota
ENOG410XTBZ LUCA
GeneTreeiENSGT00950000182917
HOGENOMiHOG000007788
InParanoidiQ8N584
OMAiFFHRAVK
OrthoDBi269827at2759
PhylomeDBiQ8N584
TreeFamiTF313761

Miscellaneous databases

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...
ChiTaRSi
TTC39C human

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...
GenomeRNAii
125488
PharosiQ8N584

Protein Ontology

More...
PROi
PR:Q8N584

Gene expression databases

BgeeiENSG00000168234 Expressed in 175 organ(s), highest expression level in liver
ExpressionAtlasiQ8N584 baseline and differential
GenevisibleiQ8N584 HS

Family and domain databases

InterProiView protein in InterPro
IPR019412 Iml2/TPR_39
IPR011990 TPR-like_helical_dom_sf
PANTHERiPTHR31859 PTHR31859, 1 hit
PfamiView protein in Pfam
PF10300 DUF3808, 1 hit
SUPFAMiSSF48452 SSF48452, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiTT39C_HUMAN
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q8N584
Secondary accession number(s): B7WP63
, J3QRR1, Q0VAJ2, Q8N284
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: February 6, 2007
Last sequence update: February 6, 2007
Last modified: October 16, 2019
This is version 129 of the entry and version 2 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. Human chromosome 18
    Human chromosome 18: entries, gene names and cross-references to MIM
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