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Protein

Zinc finger protein 276

Gene

ZNF276

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:4 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

May be involved in transcriptional regulation.

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Function’ section specifies the position(s) and type(s) of zinc fingers within the protein.<p><a href='/help/zn_fing' target='_top'>More...</a></p>Zinc fingeri434 – 458C2H2-type 1PROSITE-ProRule annotationAdd BLAST25
Zinc fingeri465 – 490C2H2-type 2PROSITE-ProRule annotationAdd BLAST26
Zinc fingeri496 – 518C2H2-type 3PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri524 – 546C2H2-type 4PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri554 – 577C2H2-type 5PROSITE-ProRule annotationAdd BLAST24

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionDNA-binding
Biological processTranscription, Transcription regulation
LigandMetal-binding, Zinc

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Zinc finger protein 276
Short name:
Zfp-276
Alternative name(s):
Zinc finger protein 477
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:ZNF276
Synonyms:CENP-Z, ZFP276, ZNF477
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 16

Organism-specific databases

Eukaryotic Pathogen Database Resources

More...
EuPathDBi
HostDB:ENSG00000158805.11

Human Gene Nomenclature Database

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HGNCi
HGNC:23330 ZNF276

Online Mendelian Inheritance in Man (OMIM)

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MIMi
608460 gene

neXtProt; the human protein knowledge platform

More...
neXtProti
NX_Q8N554

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Centromere, Chromosome, Kinetochore, Nucleus

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

Open Targets

More...
OpenTargetsi
ENSG00000158805

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...
PharmGKBi
PA134935042

Polymorphism and mutation databases

BioMuta curated single-nucleotide variation and disease association database

More...
BioMutai
ZNF276

Domain mapping of disease mutations (DMDM)

More...
DMDMi
296453082

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00000473231 – 614Zinc finger protein 276Add BLAST614

Proteomic databases

Encyclopedia of Proteome Dynamics

More...
EPDi
Q8N554

jPOST - Japan Proteome Standard Repository/Database

More...
jPOSTi
Q8N554

MaxQB - The MaxQuant DataBase

More...
MaxQBi
Q8N554

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q8N554

PeptideAtlas

More...
PeptideAtlasi
Q8N554

PRoteomics IDEntifications database

More...
PRIDEi
Q8N554

ProteomicsDB human proteome resource

More...
ProteomicsDBi
72002
72003 [Q8N554-2]

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
Q8N554

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
Q8N554

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSG00000158805 Expressed in 180 organ(s), highest expression level in right hemisphere of cerebellum

CleanEx database of gene expression profiles

More...
CleanExi
HS_ZNF276

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
Q8N554 baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
Q8N554 HS

Organism-specific databases

Human Protein Atlas

More...
HPAi
HPA021309
HPA022255

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the '<a href="http://www.uniprot.org/help/interaction_section%27">Interaction</a> section provides information about binary protein-protein interactions. The data presented in this section are a quality-filtered subset of binary interactions automatically derived from the <a href="http://www.ebi.ac.uk/intact/">IntAct database</a>. It is updated on a monthly basis. Each binary interaction is displayed on a separate line.<p><a href='/help/binary_interactions' target='_top'>More...</a></p>Binary interactionsi

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGrid)

More...
BioGridi
124982, 12 interactors

Protein interaction database and analysis system

More...
IntActi
Q8N554, 8 interactors

Molecular INTeraction database

More...
MINTi
Q8N554

STRING: functional protein association networks

More...
STRINGi
9606.ENSP00000415836

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

Protein Model Portal of the PSI-Nature Structural Biology Knowledgebase

More...
ProteinModelPortali
Q8N554

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
Q8N554

Database of comparative protein structure models

More...
ModBasei
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family_and_domains_section">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini79 – 153ZADAdd BLAST75

Zinc finger

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Zinc fingeri434 – 458C2H2-type 1PROSITE-ProRule annotationAdd BLAST25
Zinc fingeri465 – 490C2H2-type 2PROSITE-ProRule annotationAdd BLAST26
Zinc fingeri496 – 518C2H2-type 3PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri524 – 546C2H2-type 4PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri554 – 577C2H2-type 5PROSITE-ProRule annotationAdd BLAST24

Keywords - Domaini

Repeat, Zinc-finger

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG1721 Eukaryota
COG5048 LUCA

Ensembl GeneTree

More...
GeneTreei
ENSGT00940000158841

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
HOG000155790

The HOVERGEN Database of Homologous Vertebrate Genes

More...
HOVERGENi
HBG061026

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q8N554

Identification of Orthologs from Complete Genome Data

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OMAi
IQAVWGC

Database of Orthologous Groups

More...
OrthoDBi
1318335at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q8N554

TreeFam database of animal gene trees

More...
TreeFami
TF332664

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR012934 Znf_AD
IPR036236 Znf_C2H2_sf
IPR013087 Znf_C2H2_type

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF07776 zf-AD, 1 hit
PF00096 zf-C2H2, 2 hits

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00355 ZnF_C2H2, 5 hits

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF57667 SSF57667, 2 hits

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS00028 ZINC_FINGER_C2H2_1, 5 hits
PS50157 ZINC_FINGER_C2H2_2, 4 hits

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>.<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequences (2+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry describes 2 <p>This subsection of the ‘Sequence’ section lists the alternative protein sequences (isoforms) that can be generated from the same gene by a single or by the combination of up to four biological events (alternative promoter usage, alternative splicing, alternative initiation and ribosomal frameshifting). Additionally, this section gives relevant information on each alternative protein isoform.<p><a href='/help/alternative_products' target='_top'>More...</a></p> isoformsi produced by alternative splicing. AlignAdd to basket

This entry has 2 described isoforms and 4 potential isoforms that are computationally mapped.Show allAlign All

Isoform 1 (identifier: Q8N554-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide
        10         20         30         40         50
MKRDRLGRFL SPGSSRQCGA SDGGGGVSRT RGRPSLSGGP RVDGATARRA
60 70 80 90 100
WGPVGSCGDA GEDGADEAGA GRALAMGHCR LCHGKFSSRS LRSISERAPG
110 120 130 140 150
ASMERPSAEE RVLVRDFQRL LGVAVRQDPT LSPFVCKSCH AQFYQCHSLL
160 170 180 190 200
KSFLQRVNAS PAGRRKPCAK VGAQPPTGAE EGACLVDLIT SSPQCLHGLV
210 220 230 240 250
GWVHGHAASC GALPHLQRTL SSEYCGVIQV VWGCDQGHDY TMDTSSSCKA
260 270 280 290 300
FLLDSALAVK WPWDKETAPR LPQHRGWNPG DAPQTSQGRG TGTPVGAETK
310 320 330 340 350
TLPSTDVAQP PSDSDAVGPR SGFPPQPSLP LCRAPGQLGE KQLPSSTSDD
360 370 380 390 400
RVKDEFSDLS EGDVLSEDEN DKKQNAQSSD ESFEPYPERK VSGKKSESKE
410 420 430 440 450
AKKSEEPRIR KKPGPKPGWK KKLRCEREEL PTIYKCPYQG CTAVYRGADG
460 470 480 490 500
MKKHIKEHHE EVRERPCPHP GCNKVFMIDR YLQRHVKLIH TEVRNYICDE
510 520 530 540 550
CGQTFKQRKH LLVHQMRHSG AKPLQCEVCG FQCRQRASLK YHMTKHKAET
560 570 580 590 600
ELDFACDQCG RRFEKAHNLN VHMSMVHPLT QTQDKALPLE AEPPPGPPSP
610
SVTTEGQAVK PEPT
Length:614
Mass (Da):67,219
Last modified:May 18, 2010 - v4
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iD63256CFD7DC5040
GO
Isoform 2 (identifier: Q8N554-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     1-75: Missing.

Show »
Length:539
Mass (Da):59,850
Checksum:iCA08E6D3F3534F37
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 4 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
H3BTK0H3BTK0_HUMAN
Zinc finger protein 276
ZNF276
433Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
H3BTT0H3BTT0_HUMAN
Zinc finger protein 276
ZNF276
355Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
H3BPT7H3BPT7_HUMAN
Zinc finger protein 276
ZNF276
280Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
H3BPJ6H3BPJ6_HUMAN
Zinc finger protein 276
ZNF276
94Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

<p>This subsection of the ‘Sequence’ section reports difference(s) between the protein sequence shown in the UniProtKB entry and other available protein sequences derived from the same gene.<p><a href='/help/sequence_caution' target='_top'>More...</a></p>Sequence cautioni

The sequence AAH32781 differs from that shown. Reason: Erroneous initiation. Translation N-terminally shortened.Curated
The sequence AAI10349 differs from that shown. Reason: Erroneous initiation. Translation N-terminally extended.Curated

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti104E → V in AK026482 (PubMed:15616553).Curated1
Sequence conflicti180E → G in AK026482 (PubMed:15616553).Curated1
Sequence conflicti413P → Q in AAQ15128 (PubMed:15489334).Curated1
Sequence conflicti413P → Q in AAQ15129 (PubMed:15489334).Curated1
Sequence conflicti434Y → H in AAI07604 (PubMed:14605947).Curated1

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section describes natural variant(s) of the protein sequence.<p><a href='/help/variant' target='_top'>More...</a></p>Natural variantiVAR_032708263W → R2 PublicationsCorresponds to variant dbSNP:rs6500437Ensembl.1
Natural variantiVAR_019125275R → W May increase breast cancer risk. 1 Publication1
Natural variantiVAR_032709351R → W1 PublicationCorresponds to variant dbSNP:rs17719249Ensembl.1
Natural variantiVAR_019126605E → D1 PublicationCorresponds to variant dbSNP:rs17227424Ensembl.1

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section describes the sequence of naturally occurring alternative protein isoform(s). The changes in the amino acid sequence may be due to alternative splicing, alternative promoter usage, alternative initiation, or ribosomal frameshifting. The information stored in this subsection is used to automatically construct alternative protein sequence(s) for display.<p><a href='/help/var_seq' target='_top'>More...</a></p>Alternative sequenceiVSP_0261041 – 75Missing in isoform 2. 2 PublicationsAdd BLAST75

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

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EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AF354755 mRNA Translation: AAQ15128.1
AF354756 mRNA Translation: AAQ15129.1
AC005360 Genomic DNA No translation available.
AC010538 Genomic DNA No translation available.
BC032781 mRNA Translation: AAH32781.2 Different initiation.
BC107603 mRNA Translation: AAI07604.1
BC110348 mRNA Translation: AAI10349.1 Different initiation.
AK026482 mRNA No translation available.

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS10986.1 [Q8N554-2]
CCDS45554.1 [Q8N554-1]

NCBI Reference Sequences

More...
RefSeqi
NP_001106997.1, NM_001113525.1 [Q8N554-1]
NP_689500.2, NM_152287.3 [Q8N554-2]

UniGene gene-oriented nucleotide sequence clusters

More...
UniGenei
Hs.290154

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENST00000289816; ENSP00000289816; ENSG00000158805 [Q8N554-2]
ENST00000443381; ENSP00000415836; ENSG00000158805 [Q8N554-1]

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
92822

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
hsa:92822

UCSC genome browser

More...
UCSCi
uc002foq.5 human [Q8N554-1]

Keywords - Coding sequence diversityi

Alternative splicing, Polymorphism

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF354755 mRNA Translation: AAQ15128.1
AF354756 mRNA Translation: AAQ15129.1
AC005360 Genomic DNA No translation available.
AC010538 Genomic DNA No translation available.
BC032781 mRNA Translation: AAH32781.2 Different initiation.
BC107603 mRNA Translation: AAI07604.1
BC110348 mRNA Translation: AAI10349.1 Different initiation.
AK026482 mRNA No translation available.
CCDSiCCDS10986.1 [Q8N554-2]
CCDS45554.1 [Q8N554-1]
RefSeqiNP_001106997.1, NM_001113525.1 [Q8N554-1]
NP_689500.2, NM_152287.3 [Q8N554-2]
UniGeneiHs.290154

3D structure databases

ProteinModelPortaliQ8N554
SMRiQ8N554
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi124982, 12 interactors
IntActiQ8N554, 8 interactors
MINTiQ8N554
STRINGi9606.ENSP00000415836

PTM databases

iPTMnetiQ8N554
PhosphoSitePlusiQ8N554

Polymorphism and mutation databases

BioMutaiZNF276
DMDMi296453082

Proteomic databases

EPDiQ8N554
jPOSTiQ8N554
MaxQBiQ8N554
PaxDbiQ8N554
PeptideAtlasiQ8N554
PRIDEiQ8N554
ProteomicsDBi72002
72003 [Q8N554-2]

Protocols and materials databases

The DNASU plasmid repository

More...
DNASUi
92822
Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000289816; ENSP00000289816; ENSG00000158805 [Q8N554-2]
ENST00000443381; ENSP00000415836; ENSG00000158805 [Q8N554-1]
GeneIDi92822
KEGGihsa:92822
UCSCiuc002foq.5 human [Q8N554-1]

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
92822
EuPathDBiHostDB:ENSG00000158805.11

GeneCards: human genes, protein and diseases

More...
GeneCardsi
ZNF276
HGNCiHGNC:23330 ZNF276
HPAiHPA021309
HPA022255
MIMi608460 gene
neXtProtiNX_Q8N554
OpenTargetsiENSG00000158805
PharmGKBiPA134935042

GenAtlas: human gene database

More...
GenAtlasi
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Phylogenomic databases

eggNOGiKOG1721 Eukaryota
COG5048 LUCA
GeneTreeiENSGT00940000158841
HOGENOMiHOG000155790
HOVERGENiHBG061026
InParanoidiQ8N554
OMAiIQAVWGC
OrthoDBi1318335at2759
PhylomeDBiQ8N554
TreeFamiTF332664

Miscellaneous databases

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

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ChiTaRSi
ZNF276 human

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

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GenomeRNAii
92822

Protein Ontology

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PROi
PR:Q8N554

The Stanford Online Universal Resource for Clones and ESTs

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SOURCEi
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Gene expression databases

BgeeiENSG00000158805 Expressed in 180 organ(s), highest expression level in right hemisphere of cerebellum
CleanExiHS_ZNF276
ExpressionAtlasiQ8N554 baseline and differential
GenevisibleiQ8N554 HS

Family and domain databases

InterProiView protein in InterPro
IPR012934 Znf_AD
IPR036236 Znf_C2H2_sf
IPR013087 Znf_C2H2_type
PfamiView protein in Pfam
PF07776 zf-AD, 1 hit
PF00096 zf-C2H2, 2 hits
SMARTiView protein in SMART
SM00355 ZnF_C2H2, 5 hits
SUPFAMiSSF57667 SSF57667, 2 hits
PROSITEiView protein in PROSITE
PS00028 ZINC_FINGER_C2H2_1, 5 hits
PS50157 ZINC_FINGER_C2H2_2, 4 hits

ProtoNet; Automatic hierarchical classification of proteins

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ProtoNeti
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<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiZN276_HUMAN
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q8N554
Secondary accession number(s): Q0VGA1, Q2TBE8, Q3B7H7
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: July 5, 2004
Last sequence update: May 18, 2010
Last modified: January 16, 2019
This is version 134 of the entry and version 4 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Human entries with polymorphisms or disease mutations
    List of human entries with polymorphisms or disease mutations
  2. Human polymorphisms and disease mutations
    Index of human polymorphisms and disease mutations
  3. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
  4. Human chromosome 16
    Human chromosome 16: entries, gene names and cross-references to MIM
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