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Protein

T-complex protein 11-like protein 2

Gene

TCP11L2

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at transcript leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
T-complex protein 11-like protein 2
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:TCP11L2
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 12

Organism-specific databases

Eukaryotic Pathogen Database Resources

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EuPathDBi
HostDB:ENSG00000166046.10

Human Gene Nomenclature Database

More...
HGNCi
HGNC:28627 TCP11L2

neXtProt; the human protein knowledge platform

More...
neXtProti
NX_Q8N4U5

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

Open Targets

More...
OpenTargetsi
ENSG00000166046

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...
PharmGKBi
PA142670825

Polymorphism and mutation databases

BioMuta curated single-nucleotide variation and disease association database

More...
BioMutai
TCP11L2

Domain mapping of disease mutations (DMDM)

More...
DMDMi
74728903

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00003137501 – 519T-complex protein 11-like protein 2Add BLAST519

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei16PhosphoserineBy similarity1

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - PTMi

Phosphoprotein

Proteomic databases

Encyclopedia of Proteome Dynamics

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EPDi
Q8N4U5

jPOST - Japan Proteome Standard Repository/Database

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jPOSTi
Q8N4U5

MaxQB - The MaxQuant DataBase

More...
MaxQBi
Q8N4U5

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q8N4U5

PeptideAtlas

More...
PeptideAtlasi
Q8N4U5

PRoteomics IDEntifications database

More...
PRIDEi
Q8N4U5

ProteomicsDB human proteome resource

More...
ProteomicsDBi
71977

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

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iPTMneti
Q8N4U5

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
Q8N4U5

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSG00000166046 Expressed in 183 organ(s), highest expression level in corpus callosum

CleanEx database of gene expression profiles

More...
CleanExi
HS_TCP11L2

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
Q8N4U5 baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
Q8N4U5 HS

Organism-specific databases

Human Protein Atlas

More...
HPAi
HPA039483
HPA042188

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGrid)

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BioGridi
129100, 12 interactors

Protein interaction database and analysis system

More...
IntActi
Q8N4U5, 5 interactors

STRING: functional protein association networks

More...
STRINGi
9606.ENSP00000299045

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

Protein Model Portal of the PSI-Nature Structural Biology Knowledgebase

More...
ProteinModelPortali
Q8N4U5

Database of comparative protein structure models

More...
ModBasei
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi16 – 55Ser-richAdd BLAST40

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the TCP11 family.Curated

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG1981 Eukaryota
ENOG410ZDEH LUCA

Ensembl GeneTree

More...
GeneTreei
ENSGT00940000157835

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
HOG000231350

The HOVERGEN Database of Homologous Vertebrate Genes

More...
HOVERGENi
HBG008348

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q8N4U5

Identification of Orthologs from Complete Genome Data

More...
OMAi
EVSSMFK

Database of Orthologous Groups

More...
OrthoDBi
1230328at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q8N4U5

TreeFam database of animal gene trees

More...
TreeFami
TF313385

Family and domain databases

Integrated resource of protein families, domains and functional sites

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InterProi
View protein in InterPro
IPR008862 Tcp11

The PANTHER Classification System

More...
PANTHERi
PTHR12832 PTHR12832, 1 hit

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF05794 Tcp11, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>.<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequences (2+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry describes 2 <p>This subsection of the ‘Sequence’ section lists the alternative protein sequences (isoforms) that can be generated from the same gene by a single or by the combination of up to four biological events (alternative promoter usage, alternative splicing, alternative initiation and ribosomal frameshifting). Additionally, this section gives relevant information on each alternative protein isoform.<p><a href='/help/alternative_products' target='_top'>More...</a></p> isoformsi produced by alternative splicing. AlignAdd to basket

This entry has 2 described isoforms and 6 potential isoforms that are computationally mapped.Show allAlign All

Isoform 1 (identifier: Q8N4U5-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide
        10         20         30         40         50
MPFNGEKQCV GEDQPSDSDS SRFSESMASL SDYECSRQSF ASDSSSKSSS
60 70 80 90 100
PASTSPPRVV TFDEVMATAR NLSNLTLAHE IAVNENFQLK QEALPEKSLA
110 120 130 140 150
GRVKHIVHQA FWDVLDSELN ADPPEFEHAI KLFEEIREIL LSFLTPGGNR
160 170 180 190 200
LRNQICEVLD TDLIRQQAEH SAVDIQGLAN YVISTMGKLC APVRDNDIRE
210 220 230 240 250
LKATGNIVEV LRQIFHVLDL MQMDMANFTI MSLRPHLQRQ LVEYERTKFQ
260 270 280 290 300
EILEETPSAL DQTTEWIKES VNEELFSLSE SALTPGAENT SKPSLSPTLV
310 320 330 340 350
LNNSYLKLLQ WDYQKKELPE TLMTDGARLQ ELTEKLNQLK IIACLSLITN
360 370 380 390 400
NMVGAITGGL PELASRLTRI SAVLLEGMNK ETFNLKEVLN SIGIQTCVEV
410 420 430 440 450
NKTLMERGLP TLNAEIQANL IGQFSSIEEE DNPIWSLIDK RIKLYMRRLL
460 470 480 490 500
CLPSPQKCMP PMPGGLAVIQ QELEALGSQY ANIVNLNKQV YGPFYANILR
510
KLLFNEEAMG KVDASPPTN
Length:519
Mass (Da):58,091
Last modified:October 1, 2002 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iDB21CEDFECA17900
GO
Isoform 2 (identifier: Q8N4U5-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     258-266: SALDQTTEW → RKAEVAGAS
     267-519: Missing.

Note: Gene prediction based on EST data.
Show »
Length:266
Mass (Da):29,870
Checksum:i733885D7A8C4339F
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 6 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
F8W1M6F8W1M6_HUMAN
T-complex protein 11-like protein 2
TCP11L2
97Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
F8W0R5F8W0R5_HUMAN
T-complex protein 11-like protein 2
TCP11L2
131Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
F8VRQ3F8VRQ3_HUMAN
T-complex protein 11-like protein 2
TCP11L2
234Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
G3V1Z2G3V1Z2_HUMAN
T-complex 11 (Mouse) like 2, isofor...
TCP11L2 hCG_1813015
272Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
F8VU20F8VU20_HUMAN
T-complex protein 11-like protein 2
TCP11L2
60Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
F8VW27F8VW27_HUMAN
T-complex protein 11-like protein 2
TCP11L2
17Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti137R → G in BAG36762 (PubMed:14702039).Curated1
Sequence conflicti158V → A in BAG36762 (PubMed:14702039).Curated1

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section describes natural variant(s) of the protein sequence.<p><a href='/help/variant' target='_top'>More...</a></p>Natural variantiVAR_03772841A → T1 PublicationCorresponds to variant dbSNP:rs4964460Ensembl.1
Natural variantiVAR_03772982A → S. Corresponds to variant dbSNP:rs11837375Ensembl.1
Natural variantiVAR_037730261D → N. Corresponds to variant dbSNP:rs17218950Ensembl.1

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section describes the sequence of naturally occurring alternative protein isoform(s). The changes in the amino acid sequence may be due to alternative splicing, alternative promoter usage, alternative initiation, or ribosomal frameshifting. The information stored in this subsection is used to automatically construct alternative protein sequence(s) for display.<p><a href='/help/var_seq' target='_top'>More...</a></p>Alternative sequenceiVSP_055736258 – 266SALDQTTEW → RKAEVAGAS in isoform 2. Curated9
Alternative sequenceiVSP_055737267 – 519Missing in isoform 2. CuratedAdd BLAST253

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AK314055 mRNA Translation: BAG36762.1
AC079174 Genomic DNA No translation available.
AC080012 Genomic DNA No translation available.
CH471054 Genomic DNA Translation: EAW97774.1
CH471054 Genomic DNA Translation: EAW97775.1
BC033617 mRNA Translation: AAH33617.1

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS66456.1 [Q8N4U5-2]
CCDS9104.1 [Q8N4U5-1]

NCBI Reference Sequences

More...
RefSeqi
NP_001273191.1, NM_001286262.1 [Q8N4U5-2]
NP_689985.1, NM_152772.2 [Q8N4U5-1]
XP_005268824.1, XM_005268767.4 [Q8N4U5-1]
XP_005268825.1, XM_005268768.4 [Q8N4U5-1]
XP_011536431.1, XM_011538129.2 [Q8N4U5-1]
XP_011536432.1, XM_011538130.2 [Q8N4U5-1]
XP_016874616.1, XM_017019127.1 [Q8N4U5-1]
XP_016874617.1, XM_017019128.1
XP_016874618.1, XM_017019129.1 [Q8N4U5-1]
XP_016874619.1, XM_017019130.1 [Q8N4U5-1]
XP_016874620.1, XM_017019131.1 [Q8N4U5-1]

UniGene gene-oriented nucleotide sequence clusters

More...
UniGenei
Hs.696047
Hs.736922

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENST00000299045; ENSP00000299045; ENSG00000166046 [Q8N4U5-1]
ENST00000547153; ENSP00000448952; ENSG00000166046 [Q8N4U5-2]

Database of genes from NCBI RefSeq genomes

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GeneIDi
255394

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
hsa:255394

UCSC genome browser

More...
UCSCi
uc001tlm.5 human [Q8N4U5-1]

Keywords - Coding sequence diversityi

Alternative splicing, Polymorphism

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK314055 mRNA Translation: BAG36762.1
AC079174 Genomic DNA No translation available.
AC080012 Genomic DNA No translation available.
CH471054 Genomic DNA Translation: EAW97774.1
CH471054 Genomic DNA Translation: EAW97775.1
BC033617 mRNA Translation: AAH33617.1
CCDSiCCDS66456.1 [Q8N4U5-2]
CCDS9104.1 [Q8N4U5-1]
RefSeqiNP_001273191.1, NM_001286262.1 [Q8N4U5-2]
NP_689985.1, NM_152772.2 [Q8N4U5-1]
XP_005268824.1, XM_005268767.4 [Q8N4U5-1]
XP_005268825.1, XM_005268768.4 [Q8N4U5-1]
XP_011536431.1, XM_011538129.2 [Q8N4U5-1]
XP_011536432.1, XM_011538130.2 [Q8N4U5-1]
XP_016874616.1, XM_017019127.1 [Q8N4U5-1]
XP_016874617.1, XM_017019128.1
XP_016874618.1, XM_017019129.1 [Q8N4U5-1]
XP_016874619.1, XM_017019130.1 [Q8N4U5-1]
XP_016874620.1, XM_017019131.1 [Q8N4U5-1]
UniGeneiHs.696047
Hs.736922

3D structure databases

ProteinModelPortaliQ8N4U5
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi129100, 12 interactors
IntActiQ8N4U5, 5 interactors
STRINGi9606.ENSP00000299045

PTM databases

iPTMnetiQ8N4U5
PhosphoSitePlusiQ8N4U5

Polymorphism and mutation databases

BioMutaiTCP11L2
DMDMi74728903

Proteomic databases

EPDiQ8N4U5
jPOSTiQ8N4U5
MaxQBiQ8N4U5
PaxDbiQ8N4U5
PeptideAtlasiQ8N4U5
PRIDEiQ8N4U5
ProteomicsDBi71977

Protocols and materials databases

The DNASU plasmid repository

More...
DNASUi
255394
Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000299045; ENSP00000299045; ENSG00000166046 [Q8N4U5-1]
ENST00000547153; ENSP00000448952; ENSG00000166046 [Q8N4U5-2]
GeneIDi255394
KEGGihsa:255394
UCSCiuc001tlm.5 human [Q8N4U5-1]

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
255394
EuPathDBiHostDB:ENSG00000166046.10

GeneCards: human genes, protein and diseases

More...
GeneCardsi
TCP11L2
HGNCiHGNC:28627 TCP11L2
HPAiHPA039483
HPA042188
neXtProtiNX_Q8N4U5
OpenTargetsiENSG00000166046
PharmGKBiPA142670825

GenAtlas: human gene database

More...
GenAtlasi
Search...

Phylogenomic databases

eggNOGiKOG1981 Eukaryota
ENOG410ZDEH LUCA
GeneTreeiENSGT00940000157835
HOGENOMiHOG000231350
HOVERGENiHBG008348
InParanoidiQ8N4U5
OMAiEVSSMFK
OrthoDBi1230328at2759
PhylomeDBiQ8N4U5
TreeFamiTF313385

Miscellaneous databases

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...
GenomeRNAii
255394

Protein Ontology

More...
PROi
PR:Q8N4U5

Gene expression databases

BgeeiENSG00000166046 Expressed in 183 organ(s), highest expression level in corpus callosum
CleanExiHS_TCP11L2
ExpressionAtlasiQ8N4U5 baseline and differential
GenevisibleiQ8N4U5 HS

Family and domain databases

InterProiView protein in InterPro
IPR008862 Tcp11
PANTHERiPTHR12832 PTHR12832, 1 hit
PfamiView protein in Pfam
PF05794 Tcp11, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
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<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiT11L2_HUMAN
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q8N4U5
Secondary accession number(s): B2RA65, G3V1Y9
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: January 15, 2008
Last sequence update: October 1, 2002
Last modified: January 16, 2019
This is version 104 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. Human chromosome 12
    Human chromosome 12: entries, gene names and cross-references to MIM
  3. Human polymorphisms and disease mutations
    Index of human polymorphisms and disease mutations
  4. Human entries with polymorphisms or disease mutations
    List of human entries with polymorphisms or disease mutations
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