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Entry version 131 (23 Feb 2022)
Sequence version 3 (01 May 2007)
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Protein

Progestin and adipoQ receptor family member 4

Gene

PAQR4

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at transcript leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionReceptor

Enzyme and pathway databases

Pathway Commons web resource for biological pathway data

More...
PathwayCommonsi
Q8N4S7

SignaLink: a signaling pathway resource with multi-layered regulatory networks

More...
SignaLinki
Q8N4S7

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Progestin and adipoQ receptor family member 41 Publication
Alternative name(s):
Progestin and adipoQ receptor family member IV
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:PAQR4Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 16

Organism-specific databases

Human Gene Nomenclature Database

More...
HGNCi
HGNC:26386, PAQR4

Online Mendelian Inheritance in Man (OMIM)

More...
MIMi
614578, gene

neXtProt; the human protein knowledge platform

More...
neXtProti
NX_Q8N4S7

Eukaryotic Pathogen, Vector and Host Database Resources

More...
VEuPathDBi
HostDB:ENSG00000162073

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular%5Flocation%5Fsection">'Subcellular location'</a> section describes the extent of a membrane-spanning region of the protein. It denotes the presence of both alpha-helical transmembrane regions and the membrane spanning regions of beta-barrel transmembrane proteins.<p><a href='/help/transmem' target='_top'>More...</a></p>Transmembranei52 – 72HelicalSequence analysisAdd BLAST21
Transmembranei79 – 99HelicalSequence analysisAdd BLAST21
Transmembranei115 – 135HelicalSequence analysisAdd BLAST21
Transmembranei147 – 167HelicalSequence analysisAdd BLAST21
Transmembranei185 – 205HelicalSequence analysisAdd BLAST21
Transmembranei245 – 265HelicalSequence analysisAdd BLAST21

Keywords - Cellular componenti

Membrane

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

DisGeNET

More...
DisGeNETi
124222

Open Targets

More...
OpenTargetsi
ENSG00000162073

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...
PharmGKBi
PA134945614

Miscellaneous databases

Pharos NIH Druggable Genome Knowledgebase

More...
Pharosi
Q8N4S7, Tdark

Genetic variation databases

BioMuta curated single-nucleotide variation and disease association database

More...
BioMutai
PAQR4

Domain mapping of disease mutations (DMDM)

More...
DMDMi
146345478

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00002188481 – 273Progestin and adipoQ receptor family member 4Add BLAST273

Proteomic databases

Encyclopedia of Proteome Dynamics

More...
EPDi
Q8N4S7

jPOST - Japan Proteome Standard Repository/Database

More...
jPOSTi
Q8N4S7

MassIVE - Mass Spectrometry Interactive Virtual Environment

More...
MassIVEi
Q8N4S7

MaxQB - The MaxQuant DataBase

More...
MaxQBi
Q8N4S7

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q8N4S7

PeptideAtlas

More...
PeptideAtlasi
Q8N4S7

PRoteomics IDEntifications database

More...
PRIDEi
Q8N4S7

ProteomicsDB: a multi-organism proteome resource

More...
ProteomicsDBi
71962 [Q8N4S7-1]
71963 [Q8N4S7-2]
71964 [Q8N4S7-3]

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
Q8N4S7

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
Q8N4S7

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

<p>This subsection of the 'Expression' section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms. By default, the information is derived from experiments at the mRNA level, unless specified 'at protein level'.<br></br>Examples: <a href="http://www.uniprot.org/uniprot/P92958#expression">P92958</a>, <a href="http://www.uniprot.org/uniprot/Q8TDN4#expression">Q8TDN4</a>, <a href="http://www.uniprot.org/uniprot/O14734#expression">O14734</a><p><a href='/help/tissue_specificity' target='_top'>More...</a></p>Tissue specificityi

Relatively widely expressed in a range of tissues.1 Publication

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSG00000162073, Expressed in C1 segment of cervical spinal cord and 205 other tissues

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
Q8N4S7, baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
Q8N4S7, HS

Organism-specific databases

Human Protein Atlas

More...
HPAi
ENSG00000162073, Tissue enhanced (brain, retina)

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGRID)

More...
BioGRIDi
125857, 8 interactors

Protein interaction database and analysis system

More...
IntActi
Q8N4S7, 1 interactor

STRING: functional protein association networks

More...
STRINGi
9606.ENSP00000321804

Miscellaneous databases

RNAct, Protein-RNA interaction predictions for model organisms.

More...
RNActi
Q8N4S7, protein

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
Q8N4S7

Database of comparative protein structure models

More...
ModBasei
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the ADIPOR family.Curated

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG0748, Eukaryota

Ensembl GeneTree

More...
GeneTreei
ENSGT00940000157978

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
CLU_023075_0_1_1

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q8N4S7

Identification of Orthologs from Complete Genome Data

More...
OMAi
HHACPPD

Database of Orthologous Groups

More...
OrthoDBi
1524940at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q8N4S7

TreeFam database of animal gene trees

More...
TreeFami
TF323692

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR004254, AdipoR/HlyIII-related

The PANTHER Classification System

More...
PANTHERi
PTHR20855, PTHR20855, 1 hit

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF03006, HlyIII, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequences (3+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry describes 3 <p>This subsection of the 'Sequence' section lists the alternative protein sequences (isoforms) that can be generated from the same gene by a single or by the combination of up to four biological events (alternative promoter usage, alternative splicing, alternative initiation and ribosomal frameshifting). Additionally, this section gives relevant information on each alternative protein isoform.<p><a href='/help/alternative_products' target='_top'>More...</a></p> isoformsi produced by alternative splicing. AlignAdd to basket

This entry has 3 described isoforms and 2 potential isoforms that are computationally mapped.Show allAlign All

Isoform 1 (identifier: Q8N4S7-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the <p><strong>What is the canonical sequence?</strong><p><a href='/help/canonical_and_isoforms' target='_top'>More...</a></p>canonicali sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide
        10         20         30         40         50
MAFLAGPRLL DWASSPPHLQ FNKFVLTGYR PASSGSGCLR SLFYLHNELG
60 70 80 90 100
NIYTHGLALL GFLVLVPMTM PWGQLGKDGW LGGTHCVACL APPAGSVLYH
110 120 130 140 150
LFMCHQGGSA VYARLLALDM CGVCLVNTLG ALPIIHCTLA CRPWLRPAAL
160 170 180 190 200
VGYTVLSGVA GWRALTAPST SARLRAFGWQ AAARLLVFGA RGVGLGSGAP
210 220 230 240 250
GSLPCYLRMD ALALLGGLVN VARLPERWGP GRFDYWGNSH QIMHLLSVGS
260 270
ILQLHAGVVP DLLWAAHHAC PRD
Length:273
Mass (Da):29,126
Last modified:May 1, 2007 - v3
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i147C445B5EFAFFFD
GO
Isoform 2 (identifier: Q8N4S7-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     56-94: Missing.

Show »
Length:234
Mass (Da):25,152
Checksum:iEB378DE6BE387C0A
GO
Isoform 3 (identifier: Q8N4S7-3) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     56-130: Missing.

Show »
Length:198
Mass (Da):21,357
Checksum:iC2B5709D29EFE9F9
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 2 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
I3L1A2I3L1A2_HUMAN
Progestin and adipoQ receptor famil...
PAQR4
206Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
I3L265I3L265_HUMAN
Progestin and adipoQ receptor famil...
PAQR4
199Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti54T → A in BAC03821 (PubMed:14702039).Curated1
Sequence conflicti148A → T in BAC03821 (PubMed:14702039).Curated1
Sequence conflicti189G → E in BAB70758 (PubMed:14702039).Curated1

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section describes the sequence of naturally occurring alternative protein isoform(s). The changes in the amino acid sequence may be due to alternative splicing, alternative promoter usage, alternative initiation, or ribosomal frameshifting.<p><a href='/help/var_seq' target='_top'>More...</a></p>Alternative sequenceiVSP_01148256 – 130Missing in isoform 3. 1 PublicationAdd BLAST75
Alternative sequenceiVSP_01148156 – 94Missing in isoform 2. 1 PublicationAdd BLAST39

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AY424282 mRNA Translation: AAR08370.1
AK054564 mRNA Translation: BAB70758.1
AK092173 mRNA Translation: BAC03821.1
AK291373 mRNA Translation: BAF84062.1
CH471112 Genomic DNA Translation: EAW85441.1
CH471112 Genomic DNA Translation: EAW85442.1
CH471112 Genomic DNA Translation: EAW85443.1
CH471112 Genomic DNA Translation: EAW85444.1
BC033703 mRNA Translation: AAH33703.1

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS10485.1 [Q8N4S7-1]
CCDS66911.1 [Q8N4S7-2]

NCBI Reference Sequences

More...
RefSeqi
NP_001271440.1, NM_001284511.1 [Q8N4S7-2]
NP_001271441.1, NM_001284512.1
NP_689554.2, NM_152341.4 [Q8N4S7-1]

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENST00000293978; ENSP00000293978; ENSG00000162073 [Q8N4S7-2]
ENST00000318782; ENSP00000321804; ENSG00000162073

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
124222

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
hsa:124222

Matched Annotation from NCBI and EMBL-EBI (MANE) - Phase one

More...
MANE-Selecti
ENST00000318782.9; ENSP00000321804.8; NM_152341.5; NP_689554.2

UCSC genome browser

More...
UCSCi
uc002csj.5, human [Q8N4S7-1]

Keywords - Coding sequence diversityi

Alternative splicing

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AY424282 mRNA Translation: AAR08370.1
AK054564 mRNA Translation: BAB70758.1
AK092173 mRNA Translation: BAC03821.1
AK291373 mRNA Translation: BAF84062.1
CH471112 Genomic DNA Translation: EAW85441.1
CH471112 Genomic DNA Translation: EAW85442.1
CH471112 Genomic DNA Translation: EAW85443.1
CH471112 Genomic DNA Translation: EAW85444.1
BC033703 mRNA Translation: AAH33703.1
CCDSiCCDS10485.1 [Q8N4S7-1]
CCDS66911.1 [Q8N4S7-2]
RefSeqiNP_001271440.1, NM_001284511.1 [Q8N4S7-2]
NP_001271441.1, NM_001284512.1
NP_689554.2, NM_152341.4 [Q8N4S7-1]

3D structure databases

SMRiQ8N4S7
ModBaseiSearch...

Protein-protein interaction databases

BioGRIDi125857, 8 interactors
IntActiQ8N4S7, 1 interactor
STRINGi9606.ENSP00000321804

PTM databases

iPTMnetiQ8N4S7
PhosphoSitePlusiQ8N4S7

Genetic variation databases

BioMutaiPAQR4
DMDMi146345478

Proteomic databases

EPDiQ8N4S7
jPOSTiQ8N4S7
MassIVEiQ8N4S7
MaxQBiQ8N4S7
PaxDbiQ8N4S7
PeptideAtlasiQ8N4S7
PRIDEiQ8N4S7
ProteomicsDBi71962 [Q8N4S7-1]
71963 [Q8N4S7-2]
71964 [Q8N4S7-3]

Protocols and materials databases

Antibodypedia a portal for validated antibodies

More...
Antibodypediai
42629, 30 antibodies from 13 providers

The DNASU plasmid repository

More...
DNASUi
124222

Genome annotation databases

EnsembliENST00000293978; ENSP00000293978; ENSG00000162073 [Q8N4S7-2]
ENST00000318782; ENSP00000321804; ENSG00000162073
GeneIDi124222
KEGGihsa:124222
MANE-SelectiENST00000318782.9; ENSP00000321804.8; NM_152341.5; NP_689554.2
UCSCiuc002csj.5, human [Q8N4S7-1]

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
124222
DisGeNETi124222

GeneCards: human genes, protein and diseases

More...
GeneCardsi
PAQR4
HGNCiHGNC:26386, PAQR4
HPAiENSG00000162073, Tissue enhanced (brain, retina)
MIMi614578, gene
neXtProtiNX_Q8N4S7
OpenTargetsiENSG00000162073
PharmGKBiPA134945614
VEuPathDBiHostDB:ENSG00000162073

GenAtlas: human gene database

More...
GenAtlasi
Search...

Phylogenomic databases

eggNOGiKOG0748, Eukaryota
GeneTreeiENSGT00940000157978
HOGENOMiCLU_023075_0_1_1
InParanoidiQ8N4S7
OMAiHHACPPD
OrthoDBi1524940at2759
PhylomeDBiQ8N4S7
TreeFamiTF323692

Enzyme and pathway databases

PathwayCommonsiQ8N4S7
SignaLinkiQ8N4S7

Miscellaneous databases

BioGRID ORCS database of CRISPR phenotype screens

More...
BioGRID-ORCSi
124222, 21 hits in 1051 CRISPR screens

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...
ChiTaRSi
PAQR4, human

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...
GenomeRNAii
124222
PharosiQ8N4S7, Tdark

Protein Ontology

More...
PROi
PR:Q8N4S7
RNActiQ8N4S7, protein

The Stanford Online Universal Resource for Clones and ESTs

More...
SOURCEi
Search...

Gene expression databases

BgeeiENSG00000162073, Expressed in C1 segment of cervical spinal cord and 205 other tissues
ExpressionAtlasiQ8N4S7, baseline and differential
GenevisibleiQ8N4S7, HS

Family and domain databases

InterProiView protein in InterPro
IPR004254, AdipoR/HlyIII-related
PANTHERiPTHR20855, PTHR20855, 1 hit
PfamiView protein in Pfam
PF03006, HlyIII, 1 hit

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiPAQR4_HUMAN
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q8N4S7
Secondary accession number(s): A8K5Q8
, D3DUA2, D3DUA3, Q8NAS6, Q96NW1
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: August 31, 2004
Last sequence update: May 1, 2007
Last modified: February 23, 2022
This is version 131 of the entry and version 3 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. Human chromosome 16
    Human chromosome 16: entries, gene names and cross-references to MIM
  2. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
  3. SIMILARITY comments
    Index of protein domains and families
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