UniProtKB - Q8N4N7 (Q8N4N7_HUMAN)
Protein
Submitted name:
ABCC9 protein
Gene
ABCC9
Organism
Homo sapiens (Human)
Status
Functioni
GO - Molecular functioni
- ATP binding Source: InterPro
- sulfonylurea receptor activity Source: InterPro
GO - Biological processi
- potassium ion transport Source: InterPro
Names & Taxonomyi
Protein namesi | Submitted name: ABCC9 proteinImportedSubmitted name: ATP-binding cassette sub-family C member 9Imported |
Gene namesi | Name:ABCC9Imported |
Organismi | Homo sapiens (Human)Imported |
Taxonomic identifieri | 9606 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo |
Proteomesi |
|
Organism-specific databases
HGNCi | HGNC:60, ABCC9 |
VEuPathDBi | HostDB:ENSG00000069431.10 |
Subcellular locationi
Other locations
- integral component of membrane Source: UniProtKB-KW
Topology
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Transmembranei | 31 – 51 | HelicalSequence analysisAdd BLAST | 21 | |
Transmembranei | 71 – 92 | HelicalSequence analysisAdd BLAST | 22 | |
Transmembranei | 104 – 123 | HelicalSequence analysisAdd BLAST | 20 |
Keywords - Cellular componenti
MembraneExpressioni
Gene expression databases
Bgeei | ENSG00000069431, Expressed in heart and 155 other tissues |
ExpressionAtlasi | Q8N4N7, baseline and differential |
Family & Domainsi
Keywords - Domaini
Transmembrane, Transmembrane helixSequence analysisPhylogenomic databases
GeneTreei | ENSGT00940000156680 |
HOGENOMi | CLU_133883_0_0_1 |
Family and domain databases
InterProi | View protein in InterPro IPR001475, ABCC9 IPR000388, Sulphorea_rcpt |
PANTHERi | PTHR24223:SF173, PTHR24223:SF173, 1 hit |
PRINTSi | PR01092, SULFNYLUREAR |
(1+)i Sequence
Sequence statusi: Complete.
This entry has 1 described isoform and 3 potential isoforms that are computationally mapped.Show allAlign All
Q8N4N7-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MSLSFCGNNI SSYNINDGVL QNSCFVDALN LVPHVFLLFI TFPILFIGWG
60 70 80 90 100
SQSSKVQIHH NTWLHFPGHN LRWILTFALL FVHVCEIAEG IVSDSRRESR
110 120 130 140
HLHLFMPAVM GFVATTTSIV YYHNIETSNF PKLLLGFSHH ESKSCYQHS
Computationally mapped potential isoform sequencesi
There are 3 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basketO60706 | ABCC9_HUMAN | ATP-binding cassette sub-family C m... | ABCC9 SUR2 | 1,549 | Annotation score: | ||
H0YFV4 | H0YFV4_HUMAN | ATP-binding cassette sub-family C m... | ABCC9 | 1,176 | Annotation score: | ||
G3V1N6 | G3V1N6_HUMAN | ATP-binding cassette sub-family C m... | ABCC9 hCG_24790 | 170 | Annotation score: |
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AC008250 Genomic DNA No translation available. AC084806 Genomic DNA No translation available. KF459680 Genomic DNA No translation available. KF495813 Genomic DNA No translation available. KF570253 Genomic DNA No translation available. BC033804 mRNA Translation: AAH33804.1 |
Genome annotation databases
Ensembli | ENST00000326684; ENSP00000317518; ENSG00000069431 ENST00000621589; ENSP00000480233; ENSG00000069431 ENST00000636888; ENSP00000490640; ENSG00000069431 |
UCSCi | uc001rfk.3, human |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AC008250 Genomic DNA No translation available. AC084806 Genomic DNA No translation available. KF459680 Genomic DNA No translation available. KF495813 Genomic DNA No translation available. KF570253 Genomic DNA No translation available. BC033804 mRNA Translation: AAH33804.1 |
3D structure databases
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Protein-protein interaction databases
IntActi | Q8N4N7, 1 interactor |
Proteomic databases
ProteomicsDBi | 71950 |
Protocols and materials databases
Antibodypediai | 12381, 223 antibodies |
Genome annotation databases
Ensembli | ENST00000326684; ENSP00000317518; ENSG00000069431 ENST00000621589; ENSP00000480233; ENSG00000069431 ENST00000636888; ENSP00000490640; ENSG00000069431 |
UCSCi | uc001rfk.3, human |
Organism-specific databases
HGNCi | HGNC:60, ABCC9 |
OpenTargetsi | ENSG00000069431 |
VEuPathDBi | HostDB:ENSG00000069431.10 |
GenAtlasi | Search... |
Phylogenomic databases
GeneTreei | ENSGT00940000156680 |
HOGENOMi | CLU_133883_0_0_1 |
Miscellaneous databases
ChiTaRSi | ABCC9, human |
Gene expression databases
Bgeei | ENSG00000069431, Expressed in heart and 155 other tissues |
ExpressionAtlasi | Q8N4N7, baseline and differential |
Family and domain databases
InterProi | View protein in InterPro IPR001475, ABCC9 IPR000388, Sulphorea_rcpt |
PANTHERi | PTHR24223:SF173, PTHR24223:SF173, 1 hit |
PRINTSi | PR01092, SULFNYLUREAR |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | Q8N4N7_HUMAN | |
Accessioni | Q8N4N7Primary (citable) accession number: Q8N4N7 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | October 1, 2002 |
Last sequence update: | October 1, 2002 | |
Last modified: | February 10, 2021 | |
This is version 123 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) | |
Disclaimer | Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. |