SLC25A45

Functionⁱ

GO - Molecular functionⁱ

transmembrane transporter activity Source: GO_Central

View the complete GO annotation on QuickGO ...

GO - Biological processⁱ

mitochondrial transport Source: GO_Central

View the complete GO annotation on QuickGO ...

Keywordsⁱ

Biological process	Transport

Biological process

Transport

Protein family/group databases

TCDBⁱ	2.A.29.8.7 the mitochondrial carrier (mc) family

TCDBⁱ

2.A.29.8.7 the mitochondrial carrier (mc) family

Names & Taxonomyⁱ

Protein namesⁱ	Recommended name: Solute carrier family 25 member 45
Gene namesⁱ	Name:SLC25A45
Organismⁱ	Homo sapiens (Human)
Taxonomic identifierⁱ	9606 [NCBI]
Taxonomic lineageⁱ	cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Dipnotetrapodomorpha › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Boreoeutheria › Euarchontoglires › Primates › Haplorrhini › Simiiformes › Catarrhini › Hominoidea › Hominidae › Homininae › Homo
Proteomesⁱ	UP000005640 Componentⁱ: Chromosome 11

Organism-specific databases

EuPathDBⁱ	HostDB:ENSG00000162241.12
Human Gene Nomenclature Database More...HGNCⁱ	HGNC:27442 SLC25A45
MIMⁱ	610825 gene
neXtProtⁱ	NX_Q8N413

Topology

Feature key	Position(s)	DescriptionActions	Length
Transmembraneⁱ	6 – 26	Helical; Name=1Sequence analysisAdd BLAST	21
Transmembraneⁱ	63 – 83	Helical; Name=2Sequence analysisAdd BLAST	21
Transmembraneⁱ	100 – 120	Helical; Name=3Sequence analysisAdd BLAST	21
Transmembraneⁱ	166 – 186	Helical; Name=4Sequence analysisAdd BLAST	21
Transmembraneⁱ	202 – 222	Helical; Name=5Sequence analysisAdd BLAST	21
Transmembraneⁱ	266 – 286	Helical; Name=6Sequence analysisAdd BLAST	21

Keywords - Cellular componentⁱ

Membrane, Mitochondrion, Mitochondrion inner membrane

Pathology & Biotechⁱ

Organism-specific databases

DisGeNET More...DisGeNETⁱ	283130
Open Targets More...OpenTargetsⁱ	ENSG00000162241
PharmGKBⁱ	PA162403718

Polymorphism and mutation databases

BioMutaⁱ	SLC25A45
DMDMⁱ	150416125

PTM / Processingⁱ

Molecule processing

Feature key	Position(s)	DescriptionActions	Graphical view	Length
ChainⁱPRO_0000291826	1 – 288	Solute carrier family 25 member 45Add BLAST		288

Proteomic databases

PaxDbⁱ	Q8N413
PeptideAtlas More...PeptideAtlasⁱ	Q8N413
PRIDEⁱ	Q8N413
ProteomicsDBⁱ	71861 71862 [Q8N413-2] 71863 [Q8N413-3] 71864 [Q8N413-4]

Expressionⁱ

Gene expression databases

Bgeeⁱ	ENSG00000162241
CleanExⁱ	HS_SLC25A45
ExpressionAtlasⁱ	Q8N413 baseline and differential
Genevisibleⁱ	Q8N413 HS

Organism-specific databases

Human Protein Atlas More...HPAⁱ	HPA050821

HPAⁱ

HPA050821

Interactionⁱ

Protein-protein interaction databases

STRINGⁱ	9606.ENSP00000381782

STRINGⁱ

9606.ENSP00000381782

Structureⁱ

3D structure databases

ProteinModelPortalⁱ	Q8N413
SMRⁱ	Q8N413
ModBaseⁱ	Search...
MobiDBⁱ	Search...

Family & Domainsⁱ

Domains and Repeats

Feature key	Position(s)	DescriptionActions	Length
Repeatⁱ	1 – 83	Solcar 1Add BLAST	83
Repeatⁱ	97 – 191	Solcar 2Add BLAST	95
Repeatⁱ	199 – 286	Solcar 3Add BLAST	88

Sequence similaritiesⁱ

Belongs to the mitochondrial carrier (TC 2.A.29) family. [View classification]Curated

Keywords - Domainⁱ

Repeat, Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGⁱ	KOG0758 Eukaryota ENOG410XS86 LUCA
Ensembl GeneTree More...GeneTreeⁱ	ENSGT00700000104295
HOGENOMⁱ	HOG000168307
HOVERGENⁱ	HBG003500
InParanoidⁱ	Q8N413
KEGG Orthology (KO) More...KOⁱ	K15123
OMAⁱ	DENHKFR
Database of Orthologous Groups More...OrthoDBⁱ	EOG091G0HVE
PhylomeDBⁱ	Q8N413
TreeFamⁱ	TF351739

Family and domain databases

Gene3Dⁱ	1.50.40.10, 1 hit
InterProⁱ	View protein in InterPro IPR002067 Mit_carrier IPR018108 Mitochondrial_sb/sol_carrier IPR023395 Mt_carrier_dom_sf
Pfam protein domain database More...Pfamⁱ	View protein in Pfam PF00153 Mito_carr, 3 hits
PRINTSⁱ	PR00926 MITOCARRIER
SUPFAMⁱ	SSF103506 SSF103506, 1 hit
PROSITEⁱ	View protein in PROSITE PS50920 SOLCAR, 3 hits

Sequences (4)ⁱ

Sequence statusⁱ: Complete.

This entry describes 4 isoformsⁱ produced by alternative splicing. Align Add to basket Added to basket

Isoform 1 (identifier: Q8N413-1) [UniParc]FASTA Add to basket

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide

        10         20         30         40         50
MPVEEFVAGW ISGALGLVLG HPFDTVKVRL QTQTTYRGIV DCMVKIYRHE 
        60         70         80         90        100
SLLGFFKGMS FPIASIAVVN SVLFGVYSNT LLVLTATSHQ ERRAQPPSYM 
       110        120        130        140        150
HIFLAGCTGG FLQAYCLAPF DLIKVRLQNQ TEPRAQPGSP PPRYQGPVHC 
       160        170        180        190        200
AASIFREEGP RGLFRGAWAL TLRDTPTVGI YFITYEGLCR QYTPEGQNPS 
       210        220        230        240        250
SATVLVAGGF AGIASWVAAT PLDMIKSRMQ MDGLRRRVYQ GMLDCMVSSI 
       260        270        280 
RQEGLGVFFR GVTINSARAF PVNAVTFLSY EYLLRWWG

Length:288

Mass (Da):31,906

Last modified:June 26, 2007 - v2

Checksum:ⁱBD8EF1D8A2BFB296

GO

Isoform 2 (identifier: Q8N413-2) [UniParc]FASTA Add to basket

The sequence of this isoform differs from the canonical sequence as follows:
1-42: Missing.

« Hide

        10         20         30         40         50
MVKIYRHESL LGFFKGMSFP IASIAVVNSV LFGVYSNTLL VLTATSHQER 
        60         70         80         90        100
RAQPPSYMHI FLAGCTGGFL QAYCLAPFDL IKVRLQNQTE PRAQPGSPPP 
       110        120        130        140        150
RYQGPVHCAA SIFREEGPRG LFRGAWALTL RDTPTVGIYF ITYEGLCRQY 
       160        170        180        190        200
TPEGQNPSSA TVLVAGGFAG IASWVAATPL DMIKSRMQMD GLRRRVYQGM 
       210        220        230        240 
LDCMVSSIRQ EGLGVFFRGV TINSARAFPV NAVTFLSYEY LLRWWG

Note: No experimental confirmation available.

Show »

Length:246

Mass (Da):27,319

Checksum:ⁱ3DD46F818E36CA50

GO

Isoform 3 (identifier: Q8N413-3) [UniParc]FASTA Add to basket

The sequence of this isoform differs from the canonical sequence as follows:
1-42: Missing.
52-113: Missing.

« Hide

        10         20         30         40         50
MVKIYRHESA YCLAPFDLIK VRLQNQTEPR AQPGSPPPRY QGPVHCAASI 
        60         70         80         90        100
FREEGPRGLF RGAWALTLRD TPTVGIYFIT YEGLCRQYTP EGQNPSSATV 
       110        120        130        140        150
LVAGGFAGIA SWVAATPLDM IKSRMQMDGL RRRVYQGMLD CMVSSIRQEG 
       160        170        180 
LGVFFRGVTI NSARAFPVNA VTFLSYEYLL RWWG

Note: No experimental confirmation available.

Show »

Length:184

Mass (Da):20,631

Checksum:ⁱ603EA67772E2A639

GO

Isoform 4 (identifier: Q8N413-4) [UniParc]FASTA Add to basket

The sequence of this isoform differs from the canonical sequence as follows:
28-51: Missing.

« Hide

        10         20         30         40         50
MPVEEFVAGW ISGALGLVLG HPFDTVKLLG FFKGMSFPIA SIAVVNSVLF 
        60         70         80         90        100
GVYSNTLLVL TATSHQERRA QPPSYMHIFL AGCTGGFLQA YCLAPFDLIK 
       110        120        130        140        150
VRLQNQTEPR AQPGSPPPRY QGPVHCAASI FREEGPRGLF RGAWALTLRD 
       160        170        180        190        200
TPTVGIYFIT YEGLCRQYTP EGQNPSSATV LVAGGFAGIA SWVAATPLDM 
       210        220        230        240        250
IKSRMQMDGL RRRVYQGMLD CMVSSIRQEG LGVFFRGVTI NSARAFPVNA 
       260 
VTFLSYEYLL RWWG

Note: No experimental confirmation available.Curated

Show »

Length:264

Mass (Da):29,027

Checksum:ⁱ05876BDB4AA7A1C7

GO

Sequence cautionⁱ

Isoform 4 : The sequence BC041100 differs from that shown. Reason: Frameshift at position 208.Curated

Experimental Info

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Sequence conflictⁱ	153	S → P in AAT09000 (Ref. 1) Curated		1

Natural variant

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Natural variantⁱVAR_032866	224	M → V2 PublicationsCorresponds to variant dbSNP:rs624307Ensembl.		1
Natural variantⁱVAR_050135	251	R → Q. Corresponds to variant dbSNP:rs7108281Ensembl.		1

Alternative sequence

Feature key	Position(s)	DescriptionActions	Length
Alternative sequenceⁱVSP_026246	1 – 42	Missing in isoform 2 and isoform 3. 2 PublicationsAdd BLAST	42
Alternative sequenceⁱVSP_026247	28 – 51	Missing in isoform 4. 1 PublicationAdd BLAST	24
Alternative sequenceⁱVSP_026248	52 – 113	Missing in isoform 3. 1 PublicationAdd BLAST	62

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	AY597807 mRNA Translation: AAT09000.1 AP000944 Genomic DNA No translation available. BC036869 mRNA Translation: AAH36869.1 BC041100 mRNA No translation available.
The Consensus CDS (CCDS) project More...CCDSⁱ	CCDS41670.1 [Q8N413-1] CCDS41671.1 [Q8N413-2] CCDS60850.1 [Q8N413-4]
NCBI Reference Sequences More...RefSeqⁱ	NP_001070709.2, NM_001077241.2 NP_001265179.2, NM_001278250.2 NP_001265180.2, NM_001278251.2 NP_001287749.1, NM_001300820.1 NP_872362.3, NM_182556.3 XP_006718572.1, XM_006718509.3 [Q8N413-2] XP_006718573.1, XM_006718510.3 [Q8N413-2] XP_011543245.1, XM_011544943.2 [Q8N413-2] XP_011543246.1, XM_011544944.2 [Q8N413-2] XP_011543251.1, XM_011544949.2 [Q8N413-2] XP_016873052.1, XM_017017563.1 [Q8N413-2] XP_016873053.1, XM_017017564.1 [Q8N413-2] XP_016873054.1, XM_017017565.1 [Q8N413-2] XP_016873055.1, XM_017017566.1 XP_016873056.1, XM_017017567.1 [Q8N413-2] XP_016873057.1, XM_017017568.1 [Q8N413-2] XP_016873058.1, XM_017017569.1 [Q8N413-2] XP_016873059.1, XM_017017570.1 XP_016873060.1, XM_017017571.1
UniGeneⁱ	Hs.661604

Genome annotation databases

Ensemblⁱ	ENST00000294187; ENSP00000294187; ENSG00000162241 [Q8N413-2] ENST00000398802; ENSP00000381782; ENSG00000162241 [Q8N413-1] ENST00000527174; ENSP00000435489; ENSG00000162241 [Q8N413-1] ENST00000534028; ENSP00000431769; ENSG00000162241 [Q8N413-4]
GeneIDⁱ	283130
KEGGⁱ	hsa:283130
UCSC genome browser More...UCSCⁱ	uc001odq.3 human [Q8N413-1]

Keywords - Coding sequence diversityⁱ

Alternative splicing, Polymorphism

Similar proteinsⁱ

100% Identity
90% Identity
50% Identity

Protein	Similar proteins		Species	Score	Length
Q8N413	Solute carrier family 25 member 45 (Fragment)		HUMAN		118
Q8N413-2				246

Protein	Similar proteins		Species	Score	Length
Q8N413	Solute carrier family 25 member 45 (Fragment)		HUMAN		118
UPI00045DF45D		CHLSB		346
Solute carrier family 25 member 45		MANLE		288
Solute carrier family 25 member 45 isoform a		MACMU		288
Solute carrier family 25 member 45		MACFA		246
+38
Q8N413-3	Solute carrier family 25 member 45		CALJA		226
UPI000C2B337E		Ugandan red Colobus		273
Solute carrier family 25 member 45		HUMAN		226
Solute carrier family 25 member 45		PROCO		226
Solute carrier family 25 member 45		COLAP		226
+20
Q8N413-4	SLC25A45 isoform 10		PANTR		264
Solute carrier family 25 member 45		PANPA		264
Solute carrier family 25 member 45		PROCO		264
Solute carrier family 25 member 45		CALJA		264
Solute carrier family 25 member 45		COLAP		264
+12

Protein	Similar proteins		Species	Score	Length
Q8N413	Solute carrier family 25 member 45 (Fragment)		HUMAN		118
UPI00045DF45D		CHLSB		346
UPI0005F4277C		COLAP		288
SLC25A45 isoform 11		PANTR		288
Solute carrier family 25 member 45 isoform a		MACMU		288
+84
Q8N413-3	Solute carrier family 25 member 45		PAPAN		264
UPI0000D47CF0		HUMAN		264
Solute carrier family 25 member 45		RHIRO		264
Solute carrier family 25 member 45		RHIBE		264
Solute carrier family 25 member 45		NOMLE		264
+75
Q8N413-4	Solute carrier family 25 member 45		PAPAN		264
UPI0000D47CF0		HUMAN		264
Solute carrier family 25 member 45		RHIRO		264
Solute carrier family 25 member 45		RHIBE		264
Solute carrier family 25 member 45		NOMLE		264
+75

Cross-referencesⁱ

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	AY597807 mRNA Translation: AAT09000.1 AP000944 Genomic DNA No translation available. BC036869 mRNA Translation: AAH36869.1 BC041100 mRNA No translation available.
The Consensus CDS (CCDS) project More...CCDSⁱ	CCDS41670.1 [Q8N413-1] CCDS41671.1 [Q8N413-2] CCDS60850.1 [Q8N413-4]
NCBI Reference Sequences More...RefSeqⁱ	NP_001070709.2, NM_001077241.2 NP_001265179.2, NM_001278250.2 NP_001265180.2, NM_001278251.2 NP_001287749.1, NM_001300820.1 NP_872362.3, NM_182556.3 XP_006718572.1, XM_006718509.3 [Q8N413-2] XP_006718573.1, XM_006718510.3 [Q8N413-2] XP_011543245.1, XM_011544943.2 [Q8N413-2] XP_011543246.1, XM_011544944.2 [Q8N413-2] XP_011543251.1, XM_011544949.2 [Q8N413-2] XP_016873052.1, XM_017017563.1 [Q8N413-2] XP_016873053.1, XM_017017564.1 [Q8N413-2] XP_016873054.1, XM_017017565.1 [Q8N413-2] XP_016873055.1, XM_017017566.1 XP_016873056.1, XM_017017567.1 [Q8N413-2] XP_016873057.1, XM_017017568.1 [Q8N413-2] XP_016873058.1, XM_017017569.1 [Q8N413-2] XP_016873059.1, XM_017017570.1 XP_016873060.1, XM_017017571.1
UniGeneⁱ	Hs.661604

3D structure databases

ProteinModelPortalⁱ	Q8N413
SMRⁱ	Q8N413
ModBaseⁱ	Search...
MobiDBⁱ	Search...

Protein-protein interaction databases

STRINGⁱ	9606.ENSP00000381782

STRINGⁱ

9606.ENSP00000381782

Protein family/group databases

TCDBⁱ	2.A.29.8.7 the mitochondrial carrier (mc) family

TCDBⁱ

2.A.29.8.7 the mitochondrial carrier (mc) family

Polymorphism and mutation databases

BioMutaⁱ	SLC25A45
DMDMⁱ	150416125

Proteomic databases

PaxDbⁱ	Q8N413
PeptideAtlas More...PeptideAtlasⁱ	Q8N413
PRIDEⁱ	Q8N413
ProteomicsDBⁱ	71861 71862 [Q8N413-2] 71863 [Q8N413-3] 71864 [Q8N413-4]

Protocols and materials databases

The DNASU plasmid repository More...DNASUⁱ	283130
Structural Biology Knowledgebase	Search...

Genome annotation databases

Ensemblⁱ	ENST00000294187; ENSP00000294187; ENSG00000162241 [Q8N413-2] ENST00000398802; ENSP00000381782; ENSG00000162241 [Q8N413-1] ENST00000527174; ENSP00000435489; ENSG00000162241 [Q8N413-1] ENST00000534028; ENSP00000431769; ENSG00000162241 [Q8N413-4]
GeneIDⁱ	283130
KEGGⁱ	hsa:283130
UCSC genome browser More...UCSCⁱ	uc001odq.3 human [Q8N413-1]

Organism-specific databases

CTDⁱ	283130
DisGeNET More...DisGeNETⁱ	283130
EuPathDBⁱ	HostDB:ENSG00000162241.12
GeneCardsⁱ	SLC25A45
Human Gene Nomenclature Database More...HGNCⁱ	HGNC:27442 SLC25A45
Human Protein Atlas More...HPAⁱ	HPA050821
MIMⁱ	610825 gene
neXtProtⁱ	NX_Q8N413
Open Targets More...OpenTargetsⁱ	ENSG00000162241
PharmGKBⁱ	PA162403718
GenAtlas: human gene database More...GenAtlasⁱ	Search...

Phylogenomic databases

eggNOGⁱ	KOG0758 Eukaryota ENOG410XS86 LUCA
Ensembl GeneTree More...GeneTreeⁱ	ENSGT00700000104295
HOGENOMⁱ	HOG000168307
HOVERGENⁱ	HBG003500
InParanoidⁱ	Q8N413
KEGG Orthology (KO) More...KOⁱ	K15123
OMAⁱ	DENHKFR
Database of Orthologous Groups More...OrthoDBⁱ	EOG091G0HVE
PhylomeDBⁱ	Q8N413
TreeFamⁱ	TF351739

Miscellaneous databases

ChiTaRSⁱ	SLC25A45 human
GenomeRNAiⁱ	283130
Protein Ontology More...PROⁱ	PR:Q8N413
SOURCEⁱ	Search...

Gene expression databases

Bgeeⁱ	ENSG00000162241
CleanExⁱ	HS_SLC25A45
ExpressionAtlasⁱ	Q8N413 baseline and differential
Genevisibleⁱ	Q8N413 HS

Family and domain databases

Gene3Dⁱ	1.50.40.10, 1 hit
InterProⁱ	View protein in InterPro IPR002067 Mit_carrier IPR018108 Mitochondrial_sb/sol_carrier IPR023395 Mt_carrier_dom_sf
Pfam protein domain database More...Pfamⁱ	View protein in Pfam PF00153 Mito_carr, 3 hits
PRINTSⁱ	PR00926 MITOCARRIER
SUPFAMⁱ	SSF103506 SSF103506, 1 hit
PROSITEⁱ	View protein in PROSITE PS50920 SOLCAR, 3 hits
ProtoNetⁱ	Search...

Entry informationⁱ

Entry nameⁱ	S2545_HUMAN
Accessionⁱ	Q8N413Primary (citable) accession number: Q8N413 Secondary accession number(s): Q6PL49, Q8IW29
Entry historyⁱ	Integrated into UniProtKB/Swiss-Prot:	June 26, 2007
	Last sequence update:	June 26, 2007
	Last modified:	June 20, 2018
	This is version 118 of the entry and version 2 of the sequence. See complete history.
Entry statusⁱ	Reviewed (UniProtKB/Swiss-Prot)
Annotation program	Chordata Protein Annotation Program
Disclaimer	Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousⁱ

Keywords - Technical termⁱ

Complete proteome, Reference proteome

Documents

Human chromosome 11
Human chromosome 11: entries, gene names and cross-references to MIM
Human entries with polymorphisms or disease mutations
List of human entries with polymorphisms or disease mutations
Human polymorphisms and disease mutations
Index of human polymorphisms and disease mutations
MIM cross-references
Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
SIMILARITY comments
Index of protein domains and families

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UniProtKB - Q8N413 (S2545_HUMAN)

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Solute carrier family 25 member 45

Select a section on the left to see content.

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Biological processi

Protein family/group databases

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

Organism-specific databases

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Mitochondrion

Mitochondrion

Other locations

Topology

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

Polymorphism and mutation databases

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Proteomic databases

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Organism-specific databases

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Phylogenomic databases

Family and domain databases

<p>This subsection of the ‘Sequence’ section reports difference(s) between the protein sequence shown in the UniProtKB entry and other available protein sequences derived from the same gene.<p><a href='/help/sequence_caution' target='_top'>More...</a></p>Sequence cautioni

Experimental Info

Natural variant

Alternative sequence

Sequence databases

Genome annotation databases

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

3D structure databases

Protein-protein interaction databases

Protein family/group databases

Polymorphism and mutation databases

Proteomic databases

Protocols and materials databases

Genome annotation databases

Organism-specific databases

Phylogenomic databases

Miscellaneous databases

Gene expression databases

Family and domain databases

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Documents

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Functionⁱ

GO - Molecular functionⁱ

GO - Biological processⁱ

Names & Taxonomyⁱ

Subcellular locationⁱ

Pathology & Biotechⁱ

PTM / Processingⁱ

Expressionⁱ

Interactionⁱ

Structureⁱ

Family & Domainsⁱ

Sequence similaritiesⁱ

Sequence cautionⁱ

Cross-referencesⁱ

Entry informationⁱ

Miscellaneousⁱ