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Entry version 141 (18 Sep 2019)
Sequence version 2 (18 May 2010)
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Protein

Zinc finger protein 786

Gene

ZNF786

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:3 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at transcript leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

May be involved in transcriptional regulation.

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/function_section">Function</a> section specifies the position(s) and type(s) of zinc fingers within the protein.<p><a href='/help/zn_fing' target='_top'>More...</a></p>Zinc fingeri192 – 209C2H2-type 1; degeneratePROSITE-ProRule annotationAdd BLAST18
Zinc fingeri240 – 262C2H2-type 2PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri369 – 391C2H2-type 3; degeneratePROSITE-ProRule annotationAdd BLAST23
Zinc fingeri397 – 419C2H2-type 4PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri425 – 447C2H2-type 5PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri453 – 475C2H2-type 6PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri481 – 503C2H2-type 7; degeneratePROSITE-ProRule annotationAdd BLAST23
Zinc fingeri509 – 531C2H2-type 8PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri537 – 559C2H2-type 9PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri565 – 587C2H2-type 10PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri593 – 615C2H2-type 11PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri621 – 643C2H2-type 12PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri649 – 670C2H2-type 13PROSITE-ProRule annotationAdd BLAST22
Zinc fingeri676 – 698C2H2-type 14PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri704 – 726C2H2-type 15PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri732 – 754C2H2-type 16PROSITE-ProRule annotationAdd BLAST23

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionDNA-binding
Biological processTranscription, Transcription regulation
LigandMetal-binding, Zinc

Enzyme and pathway databases

Reactome - a knowledgebase of biological pathways and processes

More...
Reactomei
R-HSA-212436 Generic Transcription Pathway

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Zinc finger protein 786
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:ZNF786
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 7

Organism-specific databases

Human Gene Nomenclature Database

More...
HGNCi
HGNC:21806 ZNF786

neXtProt; the human protein knowledge platform

More...
neXtProti
NX_Q8N393

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

Keywords - Cellular componenti

Nucleus

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

DisGeNET

More...
DisGeNETi
136051

Open Targets

More...
OpenTargetsi
ENSG00000197362

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...
PharmGKBi
PA162410468

Polymorphism and mutation databases

BioMuta curated single-nucleotide variation and disease association database

More...
BioMutai
ZNF786

Domain mapping of disease mutations (DMDM)

More...
DMDMi
296453058

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00002936941 – 782Zinc finger protein 786Add BLAST782

Proteomic databases

Encyclopedia of Proteome Dynamics

More...
EPDi
Q8N393

jPOST - Japan Proteome Standard Repository/Database

More...
jPOSTi
Q8N393

MassIVE - Mass Spectrometry Interactive Virtual Environment

More...
MassIVEi
Q8N393

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q8N393

PeptideAtlas

More...
PeptideAtlasi
Q8N393

PRoteomics IDEntifications database

More...
PRIDEi
Q8N393

ProteomicsDB human proteome resource

More...
ProteomicsDBi
4612
71781 [Q8N393-1]

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
Q8N393

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
Q8N393

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSG00000197362 Expressed in 191 organ(s), highest expression level in amniotic fluid

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
Q8N393 baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
Q8N393 HS

Organism-specific databases

Human Protein Atlas

More...
HPAi
HPA021518
HPA053459

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGrid)

More...
BioGridi
126445, 7 interactors

Protein interaction database and analysis system

More...
IntActi
Q8N393, 14 interactors

STRING: functional protein association networks

More...
STRINGi
9606.ENSP00000417470

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
Q8N393

Database of comparative protein structure models

More...
ModBasei
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family_and_domains_section">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini9 – 80KRABPROSITE-ProRule annotationAdd BLAST72

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Zinc finger

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Zinc fingeri192 – 209C2H2-type 1; degeneratePROSITE-ProRule annotationAdd BLAST18
Zinc fingeri240 – 262C2H2-type 2PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri369 – 391C2H2-type 3; degeneratePROSITE-ProRule annotationAdd BLAST23
Zinc fingeri397 – 419C2H2-type 4PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri425 – 447C2H2-type 5PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri453 – 475C2H2-type 6PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri481 – 503C2H2-type 7; degeneratePROSITE-ProRule annotationAdd BLAST23
Zinc fingeri509 – 531C2H2-type 8PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri537 – 559C2H2-type 9PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri565 – 587C2H2-type 10PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri593 – 615C2H2-type 11PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri621 – 643C2H2-type 12PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri649 – 670C2H2-type 13PROSITE-ProRule annotationAdd BLAST22
Zinc fingeri676 – 698C2H2-type 14PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri704 – 726C2H2-type 15PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri732 – 754C2H2-type 16PROSITE-ProRule annotationAdd BLAST23

Keywords - Domaini

Repeat, Zinc-finger

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG1721 Eukaryota
COG5048 LUCA

Ensembl GeneTree

More...
GeneTreei
ENSGT00940000162604

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
HOG000234617

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q8N393

KEGG Orthology (KO)

More...
KOi
K09228

Identification of Orthologs from Complete Genome Data

More...
OMAi
SEQEWQN

Database of Orthologous Groups

More...
OrthoDBi
1318335at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q8N393

TreeFam database of animal gene trees

More...
TreeFami
TF326846

Family and domain databases

Conserved Domains Database

More...
CDDi
cd07765 KRAB_A-box, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR001909 KRAB
IPR036051 KRAB_dom_sf
IPR036236 Znf_C2H2_sf
IPR013087 Znf_C2H2_type

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF01352 KRAB, 1 hit
PF00096 zf-C2H2, 11 hits

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00349 KRAB, 1 hit
SM00355 ZnF_C2H2, 15 hits

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF109640 SSF109640, 1 hit
SSF57667 SSF57667, 9 hits

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS50805 KRAB, 1 hit
PS00028 ZINC_FINGER_C2H2_1, 13 hits
PS50157 ZINC_FINGER_C2H2_2, 15 hits

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequences (2+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry describes 2 <p>This subsection of the ‘Sequence’ section lists the alternative protein sequences (isoforms) that can be generated from the same gene by a single or by the combination of up to four biological events (alternative promoter usage, alternative splicing, alternative initiation and ribosomal frameshifting). Additionally, this section gives relevant information on each alternative protein isoform.<p><a href='/help/alternative_products' target='_top'>More...</a></p> isoformsi produced by alternative splicing. AlignAdd to basket

This entry has 2 described isoforms and 1 potential isoform that is computationally mapped.Show allAlign All

Isoform 1 (identifier: Q8N393-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the <div> <p><b>What is the canonical sequence?</b><p><a href='/help/canonical_and_isoforms' target='_top'>More...</a></p>canonicali sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide
        10         20         30         40         50
MAEPPRLPLT FEDVAIYFSE QEWQDLEAWQ KELYKHVMRS NYETLVSLDD
60 70 80 90 100
GLPKPELISW IEHGGEPFRK WRESQKSGNI ICSSVDMHFD PGFEEQLFWG
110 120 130 140 150
SQQAMNSGKT KSHFQLDPES QCSFGSFVSF RPDQGITLGS PQRHDARAPP
160 170 180 190 200
PLACGPSEST LKEGIPGPRN LDLPGLWDVP AWESTQHPWP VCGESCWENN
210 220 230 240 250
HLVMHQRGHS KDRTRRAWEK FNKRAETQMP WSSPRVQRHF RCGVCGKSFR
260 270 280 290 300
RKLCLLRHLA AHTGRGPFRN ADGEMCFRHE LTHPSHRLPQ QGEKPAQCTP
310 320 330 340 350
CGKRSLPVDS TQARRCQHSR EGPASWREGR GASSSVHSGQ KPGSRLPQEG
360 370 380 390 400
NSHQEGDTEA LQHGAEGPCS CSECGERSPM SARLASPCRA HTGEKPFQCA
410 420 430 440 450
HCTKRFRLRR LLQVHQHAHG GERPFSCRKC GKGFAKQCKL TEHIRVHSGE
460 470 480 490 500
KPFRCAKCGR NFRQRGQLLR HQRLHTDEKP FQCPECGLSF RLESMLRAHR
510 520 530 540 550
LRHGGERPFS CSECGRGFTH QCKLREHLRV HSGERPFQCL KCDKRFRLKG
560 570 580 590 600
ILKAHQHTHS KERPFSCGEC GKGFTRQSKL TEHLRVHSGE RPFQCPECNR
610 620 630 640 650
SFRLKGQLLS HQRLHTGERP FQCPECDKRY RVKADMKAHQ LLHSGEMPFS
660 670 680 690 700
CECGKGFVKH SKLIEHIRTH TGEKPFQCPK CDKSFRLKAQ LLSHQGLHTG
710 720 730 740 750
ERPFHCPECD KNFRERGHML RHQRIHRPER PFACGDCGKG FIYKSKLAEH
760 770 780
IRVHTKSCPA PNELDIKKRL SQLFAMIEAD WS
Length:782
Mass (Da):89,815
Last modified:May 18, 2010 - v2
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i9BDB1B88B5759F76
GO
Isoform 2 (identifier: Q8N393-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     1-37: Missing.

Note: No experimental confirmation available.
Show »
Length:745
Mass (Da):85,295
Checksum:i8A24C7CC9C94A6E4
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There is 1 potential isoform mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
H7BXP3H7BXP3_HUMAN
Zinc finger protein 786
ZNF786
696Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti503H → Q in CAD39166 (PubMed:17974005).Curated1
Sequence conflicti714R → W in CAD39166 (PubMed:17974005).Curated1

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section describes the sequence of naturally occurring alternative protein isoform(s). The changes in the amino acid sequence may be due to alternative splicing, alternative promoter usage, alternative initiation, or ribosomal frameshifting.<p><a href='/help/var_seq' target='_top'>More...</a></p>Alternative sequenceiVSP_0559711 – 37Missing in isoform 2. 1 PublicationAdd BLAST37

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AK297472 mRNA Translation: BAG59893.1
AL834510 mRNA Translation: CAD39166.1
AACC02000041 Genomic DNA Translation: EAL24426.1
AC073422 Genomic DNA No translation available.
BC128392 mRNA Translation: AAI28393.1

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS47738.1 [Q8N393-1]

NCBI Reference Sequences

More...
RefSeqi
NP_689624.2, NM_152411.3 [Q8N393-1]

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENST00000491431; ENSP00000417470; ENSG00000197362 [Q8N393-1]

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
136051

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
hsa:136051

UCSC genome browser

More...
UCSCi
uc003wfh.3 human [Q8N393-1]

Keywords - Coding sequence diversityi

Alternative splicing

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK297472 mRNA Translation: BAG59893.1
AL834510 mRNA Translation: CAD39166.1
AACC02000041 Genomic DNA Translation: EAL24426.1
AC073422 Genomic DNA No translation available.
BC128392 mRNA Translation: AAI28393.1
CCDSiCCDS47738.1 [Q8N393-1]
RefSeqiNP_689624.2, NM_152411.3 [Q8N393-1]

3D structure databases

SMRiQ8N393
ModBaseiSearch...

Protein-protein interaction databases

BioGridi126445, 7 interactors
IntActiQ8N393, 14 interactors
STRINGi9606.ENSP00000417470

PTM databases

iPTMnetiQ8N393
PhosphoSitePlusiQ8N393

Polymorphism and mutation databases

BioMutaiZNF786
DMDMi296453058

Proteomic databases

EPDiQ8N393
jPOSTiQ8N393
MassIVEiQ8N393
PaxDbiQ8N393
PeptideAtlasiQ8N393
PRIDEiQ8N393
ProteomicsDBi4612
71781 [Q8N393-1]

Protocols and materials databases

The DNASU plasmid repository

More...
DNASUi
136051
Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000491431; ENSP00000417470; ENSG00000197362 [Q8N393-1]
GeneIDi136051
KEGGihsa:136051
UCSCiuc003wfh.3 human [Q8N393-1]

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
136051
DisGeNETi136051

GeneCards: human genes, protein and diseases

More...
GeneCardsi
ZNF786
HGNCiHGNC:21806 ZNF786
HPAiHPA021518
HPA053459
neXtProtiNX_Q8N393
OpenTargetsiENSG00000197362
PharmGKBiPA162410468

GenAtlas: human gene database

More...
GenAtlasi
Search...

Phylogenomic databases

eggNOGiKOG1721 Eukaryota
COG5048 LUCA
GeneTreeiENSGT00940000162604
HOGENOMiHOG000234617
InParanoidiQ8N393
KOiK09228
OMAiSEQEWQN
OrthoDBi1318335at2759
PhylomeDBiQ8N393
TreeFamiTF326846

Enzyme and pathway databases

ReactomeiR-HSA-212436 Generic Transcription Pathway

Miscellaneous databases

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...
ChiTaRSi
ZNF786 human

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...
GenomeRNAii
136051

Pharos

More...
Pharosi
Q8N393

Protein Ontology

More...
PROi
PR:Q8N393

Gene expression databases

BgeeiENSG00000197362 Expressed in 191 organ(s), highest expression level in amniotic fluid
ExpressionAtlasiQ8N393 baseline and differential
GenevisibleiQ8N393 HS

Family and domain databases

CDDicd07765 KRAB_A-box, 1 hit
InterProiView protein in InterPro
IPR001909 KRAB
IPR036051 KRAB_dom_sf
IPR036236 Znf_C2H2_sf
IPR013087 Znf_C2H2_type
PfamiView protein in Pfam
PF01352 KRAB, 1 hit
PF00096 zf-C2H2, 11 hits
SMARTiView protein in SMART
SM00349 KRAB, 1 hit
SM00355 ZnF_C2H2, 15 hits
SUPFAMiSSF109640 SSF109640, 1 hit
SSF57667 SSF57667, 9 hits
PROSITEiView protein in PROSITE
PS50805 KRAB, 1 hit
PS00028 ZINC_FINGER_C2H2_1, 13 hits
PS50157 ZINC_FINGER_C2H2_2, 15 hits

ProtoNet; Automatic hierarchical classification of proteins

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ProtoNeti
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MobiDB: a database of protein disorder and mobility annotations

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MobiDBi
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<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiZN786_HUMAN
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q8N393
Secondary accession number(s): A1A568, B4DMI1
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: July 10, 2007
Last sequence update: May 18, 2010
Last modified: September 18, 2019
This is version 141 of the entry and version 2 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. Human chromosome 7
    Human chromosome 7: entries, gene names and cross-references to MIM
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