OSR2

Functionⁱ

Regions

Feature key	Position(s)	DescriptionActions	Length
Zinc fingerⁱ	172 – 194	C2H2-type 1PROSITE-ProRule annotationAdd BLAST	23
Zinc fingerⁱ	200 – 222	C2H2-type 2PROSITE-ProRule annotationAdd BLAST	23
Zinc fingerⁱ	228 – 250	C2H2-type 3PROSITE-ProRule annotationAdd BLAST	23
Zinc fingerⁱ	256 – 278	C2H2-type 4PROSITE-ProRule annotationAdd BLAST	23
Zinc fingerⁱ	284 – 306	C2H2-type 5; degeneratePROSITE-ProRule annotationAdd BLAST	23

GO - Molecular functionⁱ

DNA-binding transcription factor activity, RNA polymerase II-specific Source: NTNU_SB
metal ion binding Source: UniProtKB-KW
RNA polymerase II regulatory region sequence-specific DNA binding
Source: GO_Central
Inferred from biological aspect of ancestorⁱ
- 21873635
sequence-specific DNA binding Source: UniProtKB

View the complete GO annotation on QuickGO ...

GO - Biological processⁱ

bone morphogenesis Source: UniProtKB
cell differentiation Source: BHF-UCL
chondrocyte differentiation Source: BHF-UCL
embryo development ending in birth or egg hatching Source: UniProtKB
embryonic digit morphogenesis Source: BHF-UCL
embryonic forelimb morphogenesis Source: BHF-UCL
embryonic hindlimb morphogenesis Source: BHF-UCL
embryonic skeletal joint development Source: BHF-UCL
embryonic skeletal joint morphogenesis Source: BHF-UCL
embryonic skeletal limb joint morphogenesis Source: BHF-UCL
embryonic skeletal system morphogenesis Source: UniProtKB
eyelid development in camera-type eye Source: UniProtKB
head development Source: BHF-UCL
mesonephros development Source: UniProtKB
metanephros development Source: UniProtKB
middle ear morphogenesis Source: UniProtKB
negative regulation of transcription by RNA polymerase II Source: BHF-UCL
odontogenesis Source: UniProtKB
osteoblast proliferation Source: UniProtKB
positive regulation of bone mineralization Source: BHF-UCL
positive regulation of cell proliferation Source: UniProtKB
positive regulation of epithelial cell proliferation Source: UniProtKB
positive regulation of gene expression Source: UniProtKB
positive regulation of transcription, DNA-templated Source: UniProtKB
positive regulation of transcription by RNA polymerase II Source: BHF-UCL
roof of mouth development Source: UniProtKB
urogenital system development
Source: GO_Central
Inferred from biological aspect of ancestorⁱ
- 21873635

View the complete GO annotation on QuickGO ...

Keywordsⁱ

Ligand	Metal-binding, Zinc

Ligand

Metal-binding, Zinc

Names & Taxonomyⁱ

Protein namesⁱ	Recommended name: Protein odd-skipped-related 2
Gene namesⁱ	Name:OSR2
Organismⁱ	Homo sapiens (Human)
Taxonomic identifierⁱ	9606 [NCBI]
Taxonomic lineageⁱ	cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Dipnotetrapodomorpha › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Boreoeutheria › Euarchontoglires › Primates › Haplorrhini › Simiiformes › Catarrhini › Hominoidea › Hominidae › Homininae › Homo
Proteomesⁱ	UP000005640 Componentⁱ: Chromosome 8

Organism-specific databases

EuPathDBⁱ	HostDB:ENSG00000164920.9
Human Gene Nomenclature Database More...HGNCⁱ	HGNC:15830 OSR2
MIMⁱ	611297 gene
neXtProtⁱ	NX_Q8N2R0

Keywords - Cellular componentⁱ

Nucleus

Pathology & Biotechⁱ

Organism-specific databases

DisGeNET More...DisGeNETⁱ	116039
Open Targets More...OpenTargetsⁱ	ENSG00000164920
PharmGKBⁱ	PA134924513

Polymorphism and mutation databases

DMDMⁱ	146345473

DMDMⁱ

146345473

PTM / Processingⁱ

Molecule processing

Feature key	Position(s)	DescriptionActions	Graphical view	Length
ChainⁱPRO_0000047007	1 – 312	Protein odd-skipped-related 2Add BLAST		312

Proteomic databases

MaxQB - The MaxQuant DataBase More...MaxQBⁱ	Q8N2R0
PaxDbⁱ	Q8N2R0
PeptideAtlas More...PeptideAtlasⁱ	Q8N2R0
PRIDEⁱ	Q8N2R0
ProteomicsDBⁱ	71727 71728 [Q8N2R0-2]

PTM databases

iPTMnetⁱ	Q8N2R0
PhosphoSitePlusⁱ	Q8N2R0

Expressionⁱ

Gene expression databases

Bgeeⁱ	ENSG00000164920 Expressed in 170 organ(s), highest expression level in ectocervix
CleanExⁱ	HS_OSR2
ExpressionAtlasⁱ	Q8N2R0 baseline and differential
Genevisibleⁱ	Q8N2R0 HS

Organism-specific databases

Human Protein Atlas More...HPAⁱ	HPA052425 HPA063486

HPAⁱ

HPA052425
HPA063486

Interactionⁱ

Binary interactionsⁱ

With	Entry	#Exp.	IntAct	Notes
PSMA3	P25788	3	EBI-5660512,EBI-348380

With

Entry

#Exp.

IntAct

Notes

PSMA3

P25788

3

EBI-5660512,EBI-348380

Protein-protein interaction databases

BioGridⁱ	125467, 2 interactors
IntActⁱ	Q8N2R0, 3 interactors
STRINGⁱ	9606.ENSP00000297565

Structureⁱ

3D structure databases

ProteinModelPortalⁱ	Q8N2R0
SMRⁱ	Q8N2R0
ModBaseⁱ	Search...
MobiDBⁱ	Search...

Family & Domainsⁱ

Sequence similaritiesⁱ

Belongs to the Odd C2H2-type zinc-finger protein family.Curated

Zinc finger

Feature key	Position(s)	DescriptionActions	Length
Zinc fingerⁱ	172 – 194	C2H2-type 1PROSITE-ProRule annotationAdd BLAST	23
Zinc fingerⁱ	200 – 222	C2H2-type 2PROSITE-ProRule annotationAdd BLAST	23
Zinc fingerⁱ	228 – 250	C2H2-type 3PROSITE-ProRule annotationAdd BLAST	23
Zinc fingerⁱ	256 – 278	C2H2-type 4PROSITE-ProRule annotationAdd BLAST	23
Zinc fingerⁱ	284 – 306	C2H2-type 5; degeneratePROSITE-ProRule annotationAdd BLAST	23

Keywords - Domainⁱ

Repeat, Zinc-finger

Phylogenomic databases

eggNOGⁱ	KOG1721 Eukaryota COG5048 LUCA
Ensembl GeneTree More...GeneTreeⁱ	ENSGT00880000137939
HOGENOMⁱ	HOG000013107
HOVERGENⁱ	HBG054398
InParanoidⁱ	Q8N2R0
KEGG Orthology (KO) More...KOⁱ	K09215
Database of Orthologous Groups More...OrthoDBⁱ	EOG091G0LRE
PhylomeDBⁱ	Q8N2R0
TreeFamⁱ	TF350876

Family and domain databases

InterProⁱ	View protein in InterPro IPR036236 Znf_C2H2_sf IPR013087 Znf_C2H2_type
Pfam protein domain database More...Pfamⁱ	View protein in Pfam PF00096 zf-C2H2, 4 hits
SMARTⁱ	View protein in SMART SM00355 ZnF_C2H2, 5 hits
SUPFAMⁱ	SSF57667 SSF57667, 3 hits
PROSITEⁱ	View protein in PROSITE PS00028 ZINC_FINGER_C2H2_1, 5 hits PS50157 ZINC_FINGER_C2H2_2, 5 hits

Sequences (3+)ⁱ

Sequence statusⁱ: Complete.

This entry describes 3 isoformsⁱ produced by alternative splicing. Align Add to basket

This entry has 3 described isoforms and 3 potential isoforms that are computationally mapped.Show all Align All

Isoform 1 (identifier: Q8N2R0-1) [UniParc]FASTA Add to basket

Also known as: OSR2A

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide

        10         20         30         40         50
MGSKALPAPI PLHPSLQLTN YSFLQAVNTF PATVDHLQGL YGLSAVQTMH 
        60         70         80         90        100
MNHWTLGYPN VHEITRSTIT EMAAAQGLVD ARFPFPALPF TTHLFHPKQG 
       110        120        130        140        150
AIAHVLPALH KDRPRFDFAN LAVAATQEDP PKMGDLSKLS PGLGSPISGL 
       160        170        180        190        200
SKLTPDRKPS RGRLPSKTKK EFICKFCGRH FTKSYNLLIH ERTHTDERPY 
       210        220        230        240        250
TCDICHKAFR RQDHLRDHRY IHSKEKPFKC QECGKGFCQS RTLAVHKTLH 
       260        270        280        290        300
MQESPHKCPT CGRTFNQRSN LKTHLLTHTD IKPYSCEQCG KVFRRNCDLR 
       310 
RHSLTHTPRQ DF

Length:312

Mass (Da):35,513

Last modified:May 1, 2007 - v2

Checksum:ⁱ312E5A688EFB88B6

GO

Isoform 2 (identifier: Q8N2R0-2) [UniParc]FASTA Add to basket

Also known as: OSR2B

The sequence of this isoform differs from the canonical sequence as follows:
253-312: ESPHKCPTCG...SLTHTPRQDF → TSSPTAASSAAKCSGETVICGGTA

« Hide

        10         20         30         40         50
MGSKALPAPI PLHPSLQLTN YSFLQAVNTF PATVDHLQGL YGLSAVQTMH 
        60         70         80         90        100
MNHWTLGYPN VHEITRSTIT EMAAAQGLVD ARFPFPALPF TTHLFHPKQG 
       110        120        130        140        150
AIAHVLPALH KDRPRFDFAN LAVAATQEDP PKMGDLSKLS PGLGSPISGL 
       160        170        180        190        200
SKLTPDRKPS RGRLPSKTKK EFICKFCGRH FTKSYNLLIH ERTHTDERPY 
       210        220        230        240        250
TCDICHKAFR RQDHLRDHRY IHSKEKPFKC QECGKGFCQS RTLAVHKTLH 
       260        270 
MQTSSPTAAS SAAKCSGETV ICGGTA

Show »

Length:276

Mass (Da):30,573

Checksum:ⁱ4782AC3D02F8F173

GO

Isoform 3 (identifier: Q8N2R0-3) [UniParc]FASTA Add to basket

The sequence of this isoform differs from the canonical sequence as follows:
1-1: M → MGLRAEEGKR...PSAPPASRKM

« Hide

        10         20         30         40         50
MGLRAEEGKR KPPRSVRGEV SPSQGPLAQE DEARRLRSCT PACHPGKRGK 
        60         70         80         90        100
GGHRARRQRS AWDLTTHPLT HRSQELRGAA ATEGFLYVLL SHWVFVGAPR 
       110        120        130        140        150
PPASDSWKKG LVPSAPPASR KMGSKALPAP IPLHPSLQLT NYSFLQAVNT 
       160        170        180        190        200
FPATVDHLQG LYGLSAVQTM HMNHWTLGYP NVHEITRSTI TEMAAAQGLV 
       210        220        230        240        250
DARFPFPALP FTTHLFHPKQ GAIAHVLPAL HKDRPRFDFA NLAVAATQED 
       260        270        280        290        300
PPKMGDLSKL SPGLGSPISG LSKLTPDRKP SRGRLPSKTK KEFICKFCGR 
       310        320        330        340        350
HFTKSYNLLI HERTHTDERP YTCDICHKAF RRQDHLRDHR YIHSKEKPFK 
       360        370        380        390        400
CQECGKGFCQ SRTLAVHKTL HMQESPHKCP TCGRTFNQRS NLKTHLLTHT 
       410        420        430 
DIKPYSCEQC GKVFRRNCDL RRHSLTHTPR QDF

Show »

Length:433

Mass (Da):48,771

Checksum:ⁱBFEB7D6DD5697B73

GO

Computationally mapped potential isoform sequencesⁱ

There are 3 potential isoforms mapped to this entry.BLAST Align Show all Add to basket

Entry	Entry name	Protein names	Gene names	Length	Annotation

E5RGY8	E5RGY8_HUMAN	Protein odd-skipped-related 2 Protein odd-skipped-related 2	OSR2	270	Annotation score:
E5RH04	E5RH04_HUMAN	Protein odd-skipped-related 2 Protein odd-skipped-related 2	OSR2	288	Annotation score:
E5RH47	E5RH47_HUMAN	Protein odd-skipped-related 2 Protein odd-skipped-related 2	OSR2	213	Annotation score:

Experimental Info

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Sequence conflictⁱ	132	K → G in AAK74066 (Ref. 1) Curated		1
Sequence conflictⁱ	286	C → R in BAC11035 (PubMed:14702039).Curated		1

Alternative sequence

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Alternative sequenceⁱVSP_054849	1	M → MGLRAEEGKRKPPRSVRGEV SPSQGPLAQEDEARRLRSCT PACHPGKRGKGGHRARRQRS AWDLTTHPLTHRSQELRGAA ATEGFLYVLLSHWVFVGAPR PPASDSWKKGLVPSAPPASR KM in isoform 3. 1 Publication		1
Alternative sequenceⁱVSP_017121	253 – 312	ESPHK…PRQDF → TSSPTAASSAAKCSGETVIC GGTA in isoform 2. 3 PublicationsAdd BLAST		60

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	AY038072 mRNA Translation: AAK74066.1 AY038073 mRNA Translation: AAK74067.1 AK074518 mRNA Translation: BAC11035.1 AK291491 mRNA Translation: BAF84180.1 AK304654 mRNA Translation: BAG65429.1 AC016877 Genomic DNA No translation available. CH471060 Genomic DNA Translation: EAW91785.1 BC016936 mRNA Translation: AAH16936.1
The Consensus CDS (CCDS) project More...CCDSⁱ	CCDS47901.1 [Q8N2R0-1] CCDS47902.1 [Q8N2R0-2] CCDS69520.1 [Q8N2R0-3]
NCBI Reference Sequences More...RefSeqⁱ	NP_001135934.1, NM_001142462.2 [Q8N2R0-1] NP_001273770.1, NM_001286841.1 [Q8N2R0-3] NP_443727.2, NM_053001.3 [Q8N2R0-2] XP_011515129.1, XM_011516827.2 [Q8N2R0-1] XP_016868507.1, XM_017013018.1 [Q8N2R0-1]
UniGeneⁱ	Hs.253247

Genome annotation databases

Ensemblⁱ	ENST00000297565; ENSP00000297565; ENSG00000164920 [Q8N2R0-1] ENST00000435298; ENSP00000402862; ENSG00000164920 [Q8N2R0-2] ENST00000457907; ENSP00000414657; ENSG00000164920 [Q8N2R0-3] ENST00000522510; ENSP00000430780; ENSG00000164920 [Q8N2R0-1]
GeneIDⁱ	116039
KEGGⁱ	hsa:116039
UCSC genome browser More...UCSCⁱ	uc003yiq.5 human [Q8N2R0-1]

Keywords - Coding sequence diversityⁱ

Alternative splicing

Similar proteinsⁱ

100% Identity
90% Identity
50% Identity

Protein	Similar proteins		Species	Score	Length	Source
Q8N2R0	Odd-skipped related transciption factor 2		PANTR		433	UniRef100_Q8N2R0
Uncharacterized protein		PANPA		433
Odd-skipped related transciption factor 2		GORGO		312
Odd-skipped related 2		PANTR		312
Uncharacterized protein		PANPA		312
Q8N2R0-2	Uncharacterized protein		PANPA		276	UniRef100_A0A2R9ANS7
Odd-skipped related transciption factor 2		GORGO		228
UPI000387B754		HUMAN		397

Protein	Similar proteins		Species	Score	Length	Source
Q8N2R0	Odd-skipped related transciption factor 2		PANTR		433	UniRef90_Q8N2R0
Uncharacterized protein		PANPA		433
Odd-skipped related transciption factor 2		GORGO		312
Isoform 3 of Protein odd-skipped-related 2		HUMAN		433
Uncharacterized protein		NOMLE		419
+30
Q8N2R0-2	Uncharacterized protein		PANPA		276	UniRef90_A0A2R9ANS7
Odd-skipped related transciption factor 2		GORGO		228
UPI000387B754		HUMAN		397
UPI000511F794		PANTR		397

Protein	Similar proteins		Species	Score	Length	Source
Q8N2R0	Odd-skipped related transciption factor 2		PANTR		433	UniRef50_Q8N2R0
Uncharacterized protein		PANPA		433
Odd-skipped related transciption factor 2		GORGO		312
Isoform 3 of Protein odd-skipped-related 2		HUMAN		433
Uncharacterized protein		NOMLE		419
+42
Q8N2R0-2	Protein odd-skipped-related 2	)	MOUSE		312	UniRef50_Q91ZD1
Uncharacterized protein		PIG		312
Odd-skipped-related transciption factor 2		XENTR		312
protein odd-skipped-related 2 isoform X3		DIPOR		312
Uncharacterized protein		XENLA		312
+86

Cross-referencesⁱ

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	AY038072 mRNA Translation: AAK74066.1 AY038073 mRNA Translation: AAK74067.1 AK074518 mRNA Translation: BAC11035.1 AK291491 mRNA Translation: BAF84180.1 AK304654 mRNA Translation: BAG65429.1 AC016877 Genomic DNA No translation available. CH471060 Genomic DNA Translation: EAW91785.1 BC016936 mRNA Translation: AAH16936.1
CCDSⁱ	CCDS47901.1 [Q8N2R0-1] CCDS47902.1 [Q8N2R0-2] CCDS69520.1 [Q8N2R0-3]
RefSeqⁱ	NP_001135934.1, NM_001142462.2 [Q8N2R0-1] NP_001273770.1, NM_001286841.1 [Q8N2R0-3] NP_443727.2, NM_053001.3 [Q8N2R0-2] XP_011515129.1, XM_011516827.2 [Q8N2R0-1] XP_016868507.1, XM_017013018.1 [Q8N2R0-1]
UniGeneⁱ	Hs.253247

3D structure databases

ProteinModelPortalⁱ	Q8N2R0
SMRⁱ	Q8N2R0
ModBaseⁱ	Search...
MobiDBⁱ	Search...

Protein-protein interaction databases

BioGridⁱ	125467, 2 interactors
IntActⁱ	Q8N2R0, 3 interactors
STRINGⁱ	9606.ENSP00000297565

PTM databases

iPTMnetⁱ	Q8N2R0
PhosphoSitePlusⁱ	Q8N2R0

Polymorphism and mutation databases

DMDMⁱ	146345473

DMDMⁱ

146345473

Proteomic databases

MaxQBⁱ	Q8N2R0
PaxDbⁱ	Q8N2R0
PeptideAtlasⁱ	Q8N2R0
PRIDEⁱ	Q8N2R0
ProteomicsDBⁱ	71727 71728 [Q8N2R0-2]

Protocols and materials databases

Structural Biology Knowledgebase	Search...

Structural Biology Knowledgebase

Search...

Genome annotation databases

Ensemblⁱ	ENST00000297565; ENSP00000297565; ENSG00000164920 [Q8N2R0-1] ENST00000435298; ENSP00000402862; ENSG00000164920 [Q8N2R0-2] ENST00000457907; ENSP00000414657; ENSG00000164920 [Q8N2R0-3] ENST00000522510; ENSP00000430780; ENSG00000164920 [Q8N2R0-1]
GeneIDⁱ	116039
KEGGⁱ	hsa:116039
UCSCⁱ	uc003yiq.5 human [Q8N2R0-1]

Organism-specific databases

CTDⁱ	116039
DisGeNETⁱ	116039
EuPathDBⁱ	HostDB:ENSG00000164920.9
GeneCardsⁱ	OSR2
HGNCⁱ	HGNC:15830 OSR2
HPAⁱ	HPA052425 HPA063486
MIMⁱ	611297 gene
neXtProtⁱ	NX_Q8N2R0
OpenTargetsⁱ	ENSG00000164920
PharmGKBⁱ	PA134924513
GenAtlas: human gene database More...GenAtlasⁱ	Search...

Phylogenomic databases

eggNOGⁱ	KOG1721 Eukaryota COG5048 LUCA
GeneTreeⁱ	ENSGT00880000137939
HOGENOMⁱ	HOG000013107
HOVERGENⁱ	HBG054398
InParanoidⁱ	Q8N2R0
KOⁱ	K09215
OrthoDBⁱ	EOG091G0LRE
PhylomeDBⁱ	Q8N2R0
TreeFamⁱ	TF350876

Miscellaneous databases

ChiTaRSⁱ	OSR2 human
GeneWikiⁱ	OSR2_(gene)
GenomeRNAiⁱ	116039
Protein Ontology More...PROⁱ	PR:Q8N2R0
SOURCEⁱ	Search...

Gene expression databases

Bgeeⁱ	ENSG00000164920 Expressed in 170 organ(s), highest expression level in ectocervix
CleanExⁱ	HS_OSR2
ExpressionAtlasⁱ	Q8N2R0 baseline and differential
Genevisibleⁱ	Q8N2R0 HS

Family and domain databases

InterProⁱ	View protein in InterPro IPR036236 Znf_C2H2_sf IPR013087 Znf_C2H2_type
Pfamⁱ	View protein in Pfam PF00096 zf-C2H2, 4 hits
SMARTⁱ	View protein in SMART SM00355 ZnF_C2H2, 5 hits
SUPFAMⁱ	SSF57667 SSF57667, 3 hits
PROSITEⁱ	View protein in PROSITE PS00028 ZINC_FINGER_C2H2_1, 5 hits PS50157 ZINC_FINGER_C2H2_2, 5 hits
ProtoNetⁱ	Search...

Entry informationⁱ

Entry nameⁱ	OSR2_HUMAN
Accessionⁱ	Q8N2R0Primary (citable) accession number: Q8N2R0 Secondary accession number(s): A8K626 , B4E3B7, Q96AM6, Q96LB6, Q96LB7
Entry historyⁱ	Integrated into UniProtKB/Swiss-Prot:	January 24, 2006
	Last sequence update:	May 1, 2007
	Last modified:	November 7, 2018
	This is version 138 of the entry and version 2 of the sequence. See complete history.
Entry statusⁱ	Reviewed (UniProtKB/Swiss-Prot)
Annotation program	Chordata Protein Annotation Program
Disclaimer	Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousⁱ

Keywords - Technical termⁱ

Complete proteome, Reference proteome

Documents

SIMILARITY comments
Index of protein domains and families
MIM cross-references
Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
Human chromosome 8
Human chromosome 8: entries, gene names and cross-references to MIM

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UniProtKB - Q8N2R0 (OSR2_HUMAN)

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Protein odd-skipped-related 2

Select a section on the left to see content.

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Regions

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

Organism-specific databases

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Nucleus

Nucleus

Keywords - Cellular componenti

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

Polymorphism and mutation databases

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Proteomic databases

PTM databases

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Organism-specific databases

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Zinc finger

Keywords - Domaini

Phylogenomic databases

Family and domain databases

Experimental Info

Alternative sequence

Sequence databases

Genome annotation databases

Keywords - Coding sequence diversityi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

3D structure databases

Protein-protein interaction databases

PTM databases

Polymorphism and mutation databases

Proteomic databases

Protocols and materials databases

Genome annotation databases

Organism-specific databases

Phylogenomic databases

Miscellaneous databases

Gene expression databases

Family and domain databases

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

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Functionⁱ

GO - Molecular functionⁱ

GO - Biological processⁱ

Names & Taxonomyⁱ

Subcellular locationⁱ

Keywords - Cellular componentⁱ

Pathology & Biotechⁱ

PTM / Processingⁱ

Expressionⁱ

Interactionⁱ

Structureⁱ

Family & Domainsⁱ

Sequence similaritiesⁱ

Keywords - Domainⁱ

Keywords - Coding sequence diversityⁱ

Cross-referencesⁱ

Entry informationⁱ

Miscellaneousⁱ

Keywords - Technical termⁱ