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Entry version 109 (12 Aug 2020)
Sequence version 1 (01 Oct 2002)
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Protein

Lysoplasmalogenase-like protein TMEM86A

Gene

TMEM86A

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

Enzyme and pathway databases

Pathway Commons web resource for biological pathway data

More...
PathwayCommonsi
Q8N2M4

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Lysoplasmalogenase-like protein TMEM86A
Alternative name(s):
Transmembrane protein 86A
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:TMEM86A
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 11

Organism-specific databases

Eukaryotic Pathogen Database Resources

More...
EuPathDBi
HostDB:ENSG00000151117.8

Human Gene Nomenclature Database

More...
HGNCi
HGNC:26890, TMEM86A

neXtProt; the human protein knowledge platform

More...
neXtProti
NX_Q8N2M4

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular%5Flocation%5Fsection">'Subcellular location'</a> section describes the extent of a membrane-spanning region of the protein. It denotes the presence of both alpha-helical transmembrane regions and the membrane spanning regions of beta-barrel transmembrane proteins.<p><a href='/help/transmem' target='_top'>More...</a></p>Transmembranei22 – 42HelicalSequence analysisAdd BLAST21
Transmembranei44 – 64HelicalSequence analysisAdd BLAST21
Transmembranei71 – 91HelicalSequence analysisAdd BLAST21
Transmembranei93 – 113HelicalSequence analysisAdd BLAST21
Transmembranei139 – 159HelicalSequence analysisAdd BLAST21
Transmembranei175 – 195HelicalSequence analysisAdd BLAST21
Transmembranei207 – 227HelicalSequence analysisAdd BLAST21

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Cellular componenti

Membrane

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

Open Targets

More...
OpenTargetsi
ENSG00000151117

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...
PharmGKBi
PA142670737

Miscellaneous databases

Pharos NIH Druggable Genome Knowledgebase

More...
Pharosi
Q8N2M4, Tdark

Polymorphism and mutation databases

BioMuta curated single-nucleotide variation and disease association database

More...
BioMutai
TMEM86A

Domain mapping of disease mutations (DMDM)

More...
DMDMi
74728715

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00002018381 – 240Lysoplasmalogenase-like protein TMEM86AAdd BLAST240

Proteomic databases

MassIVE - Mass Spectrometry Interactive Virtual Environment

More...
MassIVEi
Q8N2M4

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q8N2M4

PeptideAtlas

More...
PeptideAtlasi
Q8N2M4

PRoteomics IDEntifications database

More...
PRIDEi
Q8N2M4

ProteomicsDB: a multi-organism proteome resource

More...
ProteomicsDBi
71716

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSG00000151117, Expressed in adrenal tissue and 153 other tissues

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
Q8N2M4, HS

Organism-specific databases

Human Protein Atlas

More...
HPAi
ENSG00000151117, Low tissue specificity

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the '<a href="http://www.uniprot.org/help/interaction%5Fsection">Interaction</a>' section provides information about binary protein-protein interactions. The data presented in this section are a quality-filtered subset of binary interactions automatically derived from the <a href="https://www.ebi.ac.uk/intact/">IntAct database</a>. It is updated at every <a href="http://www.uniprot.org/help/synchronization">UniProt release</a>.<p><a href='/help/binary_interactions' target='_top'>More...</a></p>Binary interactionsi

Hide details
Q8N2M4
With#Exp.IntAct
AQP2 [P41181]3EBI-12015604,EBI-12701138
AQP3 [Q92482]3EBI-12015604,EBI-2808854
BCL2L13 [Q9BXK5]3EBI-12015604,EBI-747430
CCDC155 [Q8N6L0]3EBI-12015604,EBI-749265
CD79A [P11912]3EBI-12015604,EBI-7797864
CISD2 [Q8N5K1]3EBI-12015604,EBI-1045797
CNR2 [P34972]3EBI-12015604,EBI-2835940
COQ9 [O75208]3EBI-12015604,EBI-724524
CPLX4 [Q7Z7G2]3EBI-12015604,EBI-18013275
CREB3L1 [Q96BA8]3EBI-12015604,EBI-6942903
EBP [Q15125]3EBI-12015604,EBI-3915253
ERGIC3 [Q9Y282]3EBI-12015604,EBI-781551
FAM209A [Q5JX71]3EBI-12015604,EBI-18304435
FFAR2 [O15552]3EBI-12015604,EBI-2833872
FKBP7 [Q9Y680]3EBI-12015604,EBI-3918971
FNDC9 [Q8TBE3]3EBI-12015604,EBI-12142257
FXYD3 - isoform 3 [Q14802-3]3EBI-12015604,EBI-12175685
GJB4 [Q9NTQ9]3EBI-12015604,EBI-12831526
GJB5 [O95377]3EBI-12015604,EBI-3909454
GJC1 [P36383]3EBI-12015604,EBI-11979659
GORAB [Q5T7V8]3EBI-12015604,EBI-3917143
GPR37L1 [O60883]3EBI-12015604,EBI-2927498
HAVCR2 [Q8TDQ0]3EBI-12015604,EBI-11472922
KCNA1 [Q09470]3EBI-12015604,EBI-8286599
LHFPL5 [Q8TAF8]3EBI-12015604,EBI-2820517
MS4A2 [Q01362]5EBI-12015604,EBI-13384102
MUC1 - isoform Y-LSP [P15941-11]3EBI-12015604,EBI-17263240
NCAPH2 - isoform 4 [Q6IBW4-4]3EBI-12015604,EBI-10247000
PDZK1IP1 [Q13113]3EBI-12015604,EBI-716063
PGRMC2 [O15173]3EBI-12015604,EBI-1050125
PI16 [Q6UXB8]3EBI-12015604,EBI-12810028
REEP4 [Q9H6H4]3EBI-12015604,EBI-7545592
RIC3 - isoform 4 [Q7Z5B4-5]3EBI-12015604,EBI-12375429
RNF185 [Q96GF1]3EBI-12015604,EBI-2340249
SCN3B [Q9NY72]3EBI-12015604,EBI-17247926
SLC10A6 [Q3KNW5]3EBI-12015604,EBI-18159983
SLC18A1 - isoform 3 [P54219-3]3EBI-12015604,EBI-17595455
SLC30A2 [Q9BRI3]3EBI-12015604,EBI-8644112
SLC35C2 - isoform 3 [Q9NQQ7-3]3EBI-12015604,EBI-17295964
SLC39A2 [Q9NP94]3EBI-12015604,EBI-12898013
SSMEM1 [Q8WWF3]3EBI-12015604,EBI-17280858
THAP4 [Q8WY91]3EBI-12015604,EBI-726691
TIMMDC1 [Q9NPL8]3EBI-12015604,EBI-6268651
TMPRSS2 - isoform 2 [O15393-2]3EBI-12015604,EBI-12345267
TYROBP [O43914]3EBI-12015604,EBI-2214794

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGRID)

More...
BioGRIDi
126831, 1 interactor

Protein interaction database and analysis system

More...
IntActi
Q8N2M4, 46 interactors

Molecular INTeraction database

More...
MINTi
Q8N2M4

STRING: functional protein association networks

More...
STRINGi
9606.ENSP00000280734

Miscellaneous databases

RNAct, Protein-RNA interaction predictions for model organisms.

More...
RNActi
Q8N2M4, protein

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the TMEM86 family.Curated

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG4804, Eukaryota

Ensembl GeneTree

More...
GeneTreei
ENSGT00390000007101

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
CLU_079086_1_1_1

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q8N2M4

Identification of Orthologs from Complete Genome Data

More...
OMAi
QGYFSHG

Database of Orthologous Groups

More...
OrthoDBi
1516092at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q8N2M4

TreeFam database of animal gene trees

More...
TreeFami
TF324663

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR012506, YhhN

The PANTHER Classification System

More...
PANTHERi
PTHR31885, PTHR31885, 1 hit

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF07947, YhhN, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

Q8N2M4-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MVSPVTVVKS EGPKLVPFFK ATCVYFVLWL PSSSPSWVST LIKCLPIFCL
60 70 80 90 100
WLFLLAHGLG FLLAHPSATR IFVGLVFSAV GDAFLIWQDQ GYFVHGLLMF
110 120 130 140 150
AVTHMFYASA FGMQPLALRT GLVMAALSGL CYALLYPCLS GAFTYLVGVY
160 170 180 190 200
VALIGFMGWR AMAGLRLAGA DWRWTELAAG SGALFFIISD LTIALNKFCF
210 220 230 240
PVPYSRALIM STYYVAQMLV ALSAVESREP VEHYRLTKAN
Length:240
Mass (Da):26,398
Last modified:October 1, 2002 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i2FABCC64A964BAA9
GO

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section describes natural variant(s) of the protein sequence.<p><a href='/help/variant' target='_top'>More...</a></p>Natural variantiVAR_034564215V → A. Corresponds to variant dbSNP:rs7945285Ensembl.1

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AK074600 mRNA Translation: BAC11084.1
BC017073 mRNA Translation: AAH17073.2
BC035692 mRNA Translation: AAH35692.1

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS7844.1

NCBI Reference Sequences

More...
RefSeqi
NP_699178.1, NM_153347.2

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENST00000280734; ENSP00000280734; ENSG00000151117

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
144110

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
hsa:144110

UCSC genome browser

More...
UCSCi
uc001moz.2, human

Keywords - Coding sequence diversityi

Polymorphism

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK074600 mRNA Translation: BAC11084.1
BC017073 mRNA Translation: AAH17073.2
BC035692 mRNA Translation: AAH35692.1
CCDSiCCDS7844.1
RefSeqiNP_699178.1, NM_153347.2

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

Protein-protein interaction databases

BioGRIDi126831, 1 interactor
IntActiQ8N2M4, 46 interactors
MINTiQ8N2M4
STRINGi9606.ENSP00000280734

Polymorphism and mutation databases

BioMutaiTMEM86A
DMDMi74728715

Proteomic databases

MassIVEiQ8N2M4
PaxDbiQ8N2M4
PeptideAtlasiQ8N2M4
PRIDEiQ8N2M4
ProteomicsDBi71716

Protocols and materials databases

Antibodypedia a portal for validated antibodies

More...
Antibodypediai
71292, 17 antibodies

The DNASU plasmid repository

More...
DNASUi
144110

Genome annotation databases

EnsembliENST00000280734; ENSP00000280734; ENSG00000151117
GeneIDi144110
KEGGihsa:144110
UCSCiuc001moz.2, human

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
144110
EuPathDBiHostDB:ENSG00000151117.8

GeneCards: human genes, protein and diseases

More...
GeneCardsi
TMEM86A
HGNCiHGNC:26890, TMEM86A
HPAiENSG00000151117, Low tissue specificity
neXtProtiNX_Q8N2M4
OpenTargetsiENSG00000151117
PharmGKBiPA142670737

GenAtlas: human gene database

More...
GenAtlasi
Search...

Phylogenomic databases

eggNOGiKOG4804, Eukaryota
GeneTreeiENSGT00390000007101
HOGENOMiCLU_079086_1_1_1
InParanoidiQ8N2M4
OMAiQGYFSHG
OrthoDBi1516092at2759
PhylomeDBiQ8N2M4
TreeFamiTF324663

Enzyme and pathway databases

PathwayCommonsiQ8N2M4

Miscellaneous databases

BioGRID ORCS database of CRISPR phenotype screens

More...
BioGRID-ORCSi
144110, 5 hits in 873 CRISPR screens

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...
GenomeRNAii
144110
PharosiQ8N2M4, Tdark

Protein Ontology

More...
PROi
PR:Q8N2M4
RNActiQ8N2M4, protein

Gene expression databases

BgeeiENSG00000151117, Expressed in adrenal tissue and 153 other tissues
GenevisibleiQ8N2M4, HS

Family and domain databases

InterProiView protein in InterPro
IPR012506, YhhN
PANTHERiPTHR31885, PTHR31885, 1 hit
PfamiView protein in Pfam
PF07947, YhhN, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiTM86A_HUMAN
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q8N2M4
Secondary accession number(s): Q96AJ0
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: November 22, 2005
Last sequence update: October 1, 2002
Last modified: August 12, 2020
This is version 109 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. Human chromosome 11
    Human chromosome 11: entries, gene names and cross-references to MIM
  2. Human entries with polymorphisms or disease mutations
    List of human entries with polymorphisms or disease mutations
  3. Human polymorphisms and disease mutations
    Index of human polymorphisms and disease mutations
  4. SIMILARITY comments
    Index of protein domains and families
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