UniProtKB - Q8N257 (H2B3B_HUMAN)
Histone H2B type 3-B
H2BU1
Functioni
Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
GO - Molecular functioni
- DNA binding Source: GO_Central
- protein heterodimerization activity Source: InterPro
GO - Biological processi
- nucleosome assembly Source: GO_Central
Keywordsi
Molecular function | DNA-binding |
Enzyme and pathway databases
PathwayCommonsi | Q8N257 |
Reactomei | R-HSA-110328, Recognition and association of DNA glycosylase with site containing an affected pyrimidine R-HSA-110329, Cleavage of the damaged pyrimidine R-HSA-110330, Recognition and association of DNA glycosylase with site containing an affected purine R-HSA-110331, Cleavage of the damaged purine R-HSA-1221632, Meiotic synapsis R-HSA-171306, Packaging Of Telomere Ends R-HSA-1912408, Pre-NOTCH Transcription and Translation R-HSA-201722, Formation of the beta-catenin:TCF transactivating complex R-HSA-212300, PRC2 methylates histones and DNA R-HSA-2299718, Condensation of Prophase Chromosomes R-HSA-2559580, Oxidative Stress Induced Senescence R-HSA-2559582, Senescence-Associated Secretory Phenotype (SASP) R-HSA-2559586, DNA Damage/Telomere Stress Induced Senescence R-HSA-3214815, HDACs deacetylate histones R-HSA-3214847, HATs acetylate histones R-HSA-427359, SIRT1 negatively regulates rRNA expression R-HSA-427389, ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression R-HSA-427413, NoRC negatively regulates rRNA expression R-HSA-5250924, B-WICH complex positively regulates rRNA expression R-HSA-5334118, DNA methylation R-HSA-5578749, Transcriptional regulation by small RNAs R-HSA-5617472, Activation of anterior HOX genes in hindbrain development during early embryogenesis R-HSA-5625886, Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3 R-HSA-5689880, Ub-specific processing proteases R-HSA-5693565, Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks R-HSA-5693571, Nonhomologous End-Joining (NHEJ) R-HSA-5693607, Processing of DNA double-strand break ends R-HSA-606279, Deposition of new CENPA-containing nucleosomes at the centromere R-HSA-68616, Assembly of the ORC complex at the origin of replication R-HSA-69473, G2/M DNA damage checkpoint R-HSA-73728, RNA Polymerase I Promoter Opening R-HSA-73772, RNA Polymerase I Promoter Escape R-HSA-8936459, RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function R-HSA-8939236, RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-9018519, Estrogen-dependent gene expression R-HSA-912446, Meiotic recombination R-HSA-9609690, HCMV Early Events R-HSA-9610379, HCMV Late Events R-HSA-9616222, Transcriptional regulation of granulopoiesis R-HSA-9670095, Inhibition of DNA recombination at telomere R-HSA-9710421, Defective pyroptosis R-HSA-977225, Amyloid fiber formation |
SignaLinki | Q8N257 |
SIGNORi | Q8N257 |
Names & Taxonomyi
Protein namesi | Recommended name: Histone H2B type 3-BAlternative name(s): H2B type 12 H2B.U histone 1Imported |
Gene namesi | |
Organismi | Homo sapiens (Human) |
Taxonomic identifieri | 9606 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo |
Proteomesi |
|
Organism-specific databases
HGNCi | HGNC:20514, H2BU1 |
MIMi | 615046, gene |
neXtProti | NX_Q8N257 |
VEuPathDBi | HostDB:ENSG00000196890 |
Subcellular locationi
Nucleus
Other locations
Cytosol
- cytosol Source: HPA
Nucleus
- nucleoplasm Source: HPA
- nucleus Source: UniProtKB
Other locations
- nucleosome Source: UniProtKB-KW
Keywords - Cellular componenti
Chromosome, Nucleosome core, NucleusPathology & Biotechi
Organism-specific databases
DisGeNETi | 128312 |
OpenTargetsi | ENSG00000196890 |
PharmGKBi | PA134875583 |
Miscellaneous databases
Pharosi | Q8N257, Tbio |
Genetic variation databases
BioMutai | HIST3H2BB |
DMDMi | 51701598 |
PTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Initiator methioninei | RemovedBy similarity | |||
ChainiPRO_0000071837 | 2 – 126 | Histone H2B type 3-BAdd BLAST | 125 |
Amino acid modifications
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Modified residuei | 2 | N-acetylprolineBy similarity | 1 | |
Modified residuei | 6 | N6-(2-hydroxyisobutyryl)lysine; alternate1 Publication | 1 | |
Modified residuei | 6 | N6-(beta-hydroxybutyryl)lysine; alternate1 Publication | 1 | |
Modified residuei | 6 | N6-acetyllysine; alternate2 Publications | 1 | |
Modified residuei | 6 | N6-butyryllysine; alternate1 Publication | 1 | |
Modified residuei | 6 | N6-crotonyllysine; alternate1 Publication | 1 | |
Modified residuei | 6 | N6-lactoyllysine; alternate1 Publication | 1 | |
Cross-linki | 6 | Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2); alternateBy similarity | ||
Modified residuei | 12 | N6-(beta-hydroxybutyryl)lysine; alternate1 Publication | 1 | |
Modified residuei | 12 | N6-acetyllysine; alternate1 Publication | 1 | |
Modified residuei | 12 | N6-crotonyllysine; alternate1 Publication | 1 | |
Modified residuei | 12 | N6-lactoyllysine; alternate1 Publication | 1 | |
Modified residuei | 13 | N6-(2-hydroxyisobutyryl)lysine; alternate1 Publication | 1 | |
Modified residuei | 13 | N6-acetyllysine; alternate2 Publications | 1 | |
Modified residuei | 13 | N6-crotonyllysine; alternate1 Publication | 1 | |
Modified residuei | 15 | Phosphoserine; by STK4/MST11 Publication | 1 | |
Modified residuei | 16 | N6-acetyllysine; alternate2 Publications | 1 | |
Modified residuei | 16 | N6-crotonyllysine; alternate1 Publication | 1 | |
Modified residuei | 16 | N6-lactoyllysine; alternate1 Publication | 1 | |
Modified residuei | 17 | N6-(beta-hydroxybutyryl)lysine; alternate1 Publication | 1 | |
Modified residuei | 17 | N6-acetyllysine; alternate1 Publication | 1 | |
Modified residuei | 17 | N6-crotonyllysine; alternate1 Publication | 1 | |
Modified residuei | 17 | N6-glutaryllysine; alternate1 Publication | 1 | |
Modified residuei | 17 | N6-lactoyllysine; alternate1 Publication | 1 | |
Modified residuei | 21 | N6-(2-hydroxyisobutyryl)lysine; alternate1 Publication | 1 | |
Modified residuei | 21 | N6-(beta-hydroxybutyryl)lysine; alternate1 Publication | 1 | |
Modified residuei | 21 | N6-acetyllysine; alternate2 Publications | 1 | |
Modified residuei | 21 | N6-butyryllysine; alternate1 Publication | 1 | |
Modified residuei | 21 | N6-crotonyllysine; alternate1 Publication | 1 | |
Modified residuei | 21 | N6-lactoyllysine; alternate1 Publication | 1 | |
Cross-linki | 21 | Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2); alternateBy similarity | ||
Modified residuei | 24 | N6-(2-hydroxyisobutyryl)lysine; alternate1 Publication | 1 | |
Modified residuei | 24 | N6-acetyllysine; alternateBy similarity | 1 | |
Modified residuei | 24 | N6-crotonyllysine; alternate1 Publication | 1 | |
Modified residuei | 24 | N6-lactoyllysine; alternate1 Publication | 1 | |
Modified residuei | 25 | N6-(2-hydroxyisobutyryl)lysine1 Publication | 1 | |
Modified residuei | 35 | N6-(2-hydroxyisobutyryl)lysine; alternate1 Publication | 1 | |
Modified residuei | 35 | N6-(beta-hydroxybutyryl)lysine; alternate1 Publication | 1 | |
Modified residuei | 35 | N6-crotonyllysine; alternate1 Publication | 1 | |
Modified residuei | 35 | N6-glutaryllysine; alternate1 Publication | 1 | |
Modified residuei | 35 | N6-succinyllysine; alternate1 Publication | 1 | |
Cross-linki | 35 | Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin); alternate1 Publication | ||
Modified residuei | 37 | Phosphoserine; by AMPKBy similarity | 1 | |
Modified residuei | 44 | N6-(2-hydroxyisobutyryl)lysine; alternate1 Publication | 1 | |
Modified residuei | 44 | N6-glutaryllysine; alternate1 Publication | 1 | |
Modified residuei | 44 | N6-lactoyllysine; alternate1 Publication | 1 | |
Modified residuei | 47 | N6-(2-hydroxyisobutyryl)lysine; alternate1 Publication | 1 | |
Modified residuei | 47 | N6-glutaryllysine; alternate1 Publication | 1 | |
Modified residuei | 47 | N6-methyllysine; alternate1 Publication | 1 | |
Modified residuei | 58 | N6,N6-dimethyllysine; alternate1 Publication | 1 | |
Modified residuei | 58 | N6-(2-hydroxyisobutyryl)lysine; alternate1 Publication | 1 | |
Modified residuei | 80 | Dimethylated arginineBy similarity | 1 | |
Modified residuei | 86 | N6,N6,N6-trimethyllysine; alternateBy similarity | 1 | |
Modified residuei | 86 | N6-(2-hydroxyisobutyryl)lysine; alternate1 Publication | 1 | |
Modified residuei | 86 | N6-(beta-hydroxybutyryl)lysine; alternate1 Publication | 1 | |
Modified residuei | 86 | N6-acetyllysine; alternateBy similarity | 1 | |
Modified residuei | 86 | N6-lactoyllysine; alternate1 Publication | 1 | |
Modified residuei | 87 | Omega-N-methylarginineBy similarity | 1 | |
Modified residuei | 93 | Omega-N-methylarginineBy similarity | 1 | |
Modified residuei | 109 | N6-(2-hydroxyisobutyryl)lysine; alternate1 Publication | 1 | |
Modified residuei | 109 | N6-glutaryllysine; alternate1 Publication | 1 | |
Modified residuei | 109 | N6-lactoyllysine; alternate1 Publication | 1 | |
Modified residuei | 109 | N6-methyllysine; alternate1 Publication | 1 | |
Glycosylationi | 113 | O-linked (GlcNAc) serineBy similarity | 1 | |
Modified residuei | 116 | PhosphothreonineBy similarity | 1 | |
Modified residuei | 117 | N6-(2-hydroxyisobutyryl)lysine; alternate1 Publication | 1 | |
Modified residuei | 117 | N6-(beta-hydroxybutyryl)lysine; alternate1 Publication | 1 | |
Modified residuei | 117 | N6-glutaryllysine; alternate1 Publication | 1 | |
Modified residuei | 117 | N6-lactoyllysine; alternate1 Publication | 1 | |
Modified residuei | 117 | N6-malonyllysine; alternate1 Publication | 1 | |
Modified residuei | 117 | N6-methylated lysine; alternateBy similarity | 1 | |
Modified residuei | 117 | N6-succinyllysine; alternate1 Publication | 1 | |
Modified residuei | 121 | N6-(2-hydroxyisobutyryl)lysine; alternate1 Publication | 1 | |
Modified residuei | 121 | N6-(beta-hydroxybutyryl)lysine; alternate1 Publication | 1 | |
Modified residuei | 121 | N6-glutaryllysine; alternate1 Publication | 1 | |
Modified residuei | 121 | N6-lactoyllysine; alternate1 Publication | 1 | |
Modified residuei | 121 | N6-succinyllysine; alternate1 Publication | 1 | |
Cross-linki | 121 | Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin); alternate3 Publications |
Post-translational modificationi
Keywords - PTMi
Acetylation, Glycoprotein, Hydroxylation, Isopeptide bond, Methylation, Phosphoprotein, Ubl conjugationProteomic databases
jPOSTi | Q8N257 |
MassIVEi | Q8N257 |
MaxQBi | Q8N257 |
PaxDbi | Q8N257 |
PeptideAtlasi | Q8N257 |
PRIDEi | Q8N257 |
ProteomicsDBi | 71655 |
TopDownProteomicsi | Q8N257 |
PTM databases
GlyGeni | Q8N257, 1 site |
iPTMneti | Q8N257 |
MetOSitei | Q8N257 |
PhosphoSitePlusi | Q8N257 |
SwissPalmi | Q8N257 |
Expressioni
Gene expression databases
Bgeei | ENSG00000196890, Expressed in ectocervix and 92 other tissues |
Organism-specific databases
HPAi | ENSG00000196890, Tissue enhanced (brain, vagina) |
Interactioni
Subunit structurei
The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.
GO - Molecular functioni
- protein heterodimerization activity Source: InterPro
Protein-protein interaction databases
BioGRIDi | 126106, 113 interactors |
CORUMi | Q8N257 |
IntActi | Q8N257, 6 interactors |
MINTi | Q8N257 |
STRINGi | 9606.ENSP00000479284 |
Miscellaneous databases
RNActi | Q8N257, protein |
Family & Domainsi
Region
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Regioni | 1 – 35 | DisorderedSequence analysisAdd BLAST | 35 |
Compositional bias
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Compositional biasi | 17 – 35 | Basic residuesSequence analysisAdd BLAST | 19 |
Sequence similaritiesi
Phylogenomic databases
eggNOGi | KOG1744, Eukaryota |
GeneTreei | ENSGT01040000240467 |
HOGENOMi | CLU_075666_2_1_1 |
InParanoidi | Q8N257 |
OMAi | FERVSCE |
OrthoDBi | 1536672at2759 |
PhylomeDBi | Q8N257 |
TreeFami | TF300212 |
Family and domain databases
Gene3Di | 1.10.20.10, 1 hit |
InterProi | View protein in InterPro IPR009072, Histone-fold IPR007125, Histone_H2A/H2B/H3 IPR000558, Histone_H2B |
PANTHERi | PTHR23428, PTHR23428, 1 hit |
Pfami | View protein in Pfam PF00125, Histone, 1 hit |
PRINTSi | PR00621, HISTONEH2B |
SMARTi | View protein in SMART SM00427, H2B, 1 hit |
SUPFAMi | SSF47113, SSF47113, 1 hit |
PROSITEi | View protein in PROSITE PS00357, HISTONE_H2B, 1 hit |
i Sequence
Sequence statusi: Complete.
: The displayed sequence is further processed into a mature form. Sequence processingi
10 20 30 40 50
MPDPSKSAPA PKKGSKKAVT KAQKKDGKKR KRGRKESYSI YVYKVLKQVH
60 70 80 90 100
PDTGISSKAM GIMNSFVNDI FERIASEASR LAHYNKRSTI TSREVQTAVR
110 120
LLLPGELAKH AVSEGTKAVT KYTSSK
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AY131981 Genomic DNA Translation: AAN59962.1 AK091220 mRNA Translation: BAC03613.1 AL139288 Genomic DNA No translation available. CH471098 Genomic DNA Translation: EAW69879.1 BC100855 mRNA Translation: AAI00856.1 BC100856 mRNA Translation: AAI00857.1 BC100857 mRNA Translation: AAI00858.2 BC100858 mRNA Translation: AAI00859.1 BC137467 mRNA Translation: AAI37468.1 BC137468 mRNA Translation: AAI37469.1 |
CCDSi | CCDS1574.1 |
RefSeqi | NP_778225.1, NM_175055.2 |
Genome annotation databases
Ensembli | ENST00000620438; ENSP00000479284; ENSG00000196890 ENST00000647549; ENSP00000496342; ENSG00000285449 |
GeneIDi | 128312 |
KEGGi | hsa:128312 |
UCSCi | uc001hsz.4, human |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AY131981 Genomic DNA Translation: AAN59962.1 AK091220 mRNA Translation: BAC03613.1 AL139288 Genomic DNA No translation available. CH471098 Genomic DNA Translation: EAW69879.1 BC100855 mRNA Translation: AAI00856.1 BC100856 mRNA Translation: AAI00857.1 BC100857 mRNA Translation: AAI00858.2 BC100858 mRNA Translation: AAI00859.1 BC137467 mRNA Translation: AAI37468.1 BC137468 mRNA Translation: AAI37469.1 |
CCDSi | CCDS1574.1 |
RefSeqi | NP_778225.1, NM_175055.2 |
3D structure databases
Select the link destinations: PDBei RCSB PDBi PDBji Links Updated | PDB entry | Method | Resolution (Å) | Chain | Positions | PDBsum |
6BIZ | X-ray | 2.10 | C | 68-82 | [»] | |
SMRi | Q8N257 | |||||
ModBasei | Search... | |||||
PDBe-KBi | Search... |
Protein-protein interaction databases
BioGRIDi | 126106, 113 interactors |
CORUMi | Q8N257 |
IntActi | Q8N257, 6 interactors |
MINTi | Q8N257 |
STRINGi | 9606.ENSP00000479284 |
PTM databases
GlyGeni | Q8N257, 1 site |
iPTMneti | Q8N257 |
MetOSitei | Q8N257 |
PhosphoSitePlusi | Q8N257 |
SwissPalmi | Q8N257 |
Genetic variation databases
BioMutai | HIST3H2BB |
DMDMi | 51701598 |
Proteomic databases
jPOSTi | Q8N257 |
MassIVEi | Q8N257 |
MaxQBi | Q8N257 |
PaxDbi | Q8N257 |
PeptideAtlasi | Q8N257 |
PRIDEi | Q8N257 |
ProteomicsDBi | 71655 |
TopDownProteomicsi | Q8N257 |
Protocols and materials databases
Antibodypediai | 57242, 50 antibodies from 7 providers |
DNASUi | 128312 |
Genome annotation databases
Ensembli | ENST00000620438; ENSP00000479284; ENSG00000196890 ENST00000647549; ENSP00000496342; ENSG00000285449 |
GeneIDi | 128312 |
KEGGi | hsa:128312 |
UCSCi | uc001hsz.4, human |
Organism-specific databases
CTDi | 128312 |
DisGeNETi | 128312 |
GeneCardsi | H2BU1 |
HGNCi | HGNC:20514, H2BU1 |
HPAi | ENSG00000196890, Tissue enhanced (brain, vagina) |
MIMi | 615046, gene |
neXtProti | NX_Q8N257 |
OpenTargetsi | ENSG00000196890 |
PharmGKBi | PA134875583 |
VEuPathDBi | HostDB:ENSG00000196890 |
GenAtlasi | Search... |
Phylogenomic databases
eggNOGi | KOG1744, Eukaryota |
GeneTreei | ENSGT01040000240467 |
HOGENOMi | CLU_075666_2_1_1 |
InParanoidi | Q8N257 |
OMAi | FERVSCE |
OrthoDBi | 1536672at2759 |
PhylomeDBi | Q8N257 |
TreeFami | TF300212 |
Enzyme and pathway databases
PathwayCommonsi | Q8N257 |
Reactomei | R-HSA-110328, Recognition and association of DNA glycosylase with site containing an affected pyrimidine R-HSA-110329, Cleavage of the damaged pyrimidine R-HSA-110330, Recognition and association of DNA glycosylase with site containing an affected purine R-HSA-110331, Cleavage of the damaged purine R-HSA-1221632, Meiotic synapsis R-HSA-171306, Packaging Of Telomere Ends R-HSA-1912408, Pre-NOTCH Transcription and Translation R-HSA-201722, Formation of the beta-catenin:TCF transactivating complex R-HSA-212300, PRC2 methylates histones and DNA R-HSA-2299718, Condensation of Prophase Chromosomes R-HSA-2559580, Oxidative Stress Induced Senescence R-HSA-2559582, Senescence-Associated Secretory Phenotype (SASP) R-HSA-2559586, DNA Damage/Telomere Stress Induced Senescence R-HSA-3214815, HDACs deacetylate histones R-HSA-3214847, HATs acetylate histones R-HSA-427359, SIRT1 negatively regulates rRNA expression R-HSA-427389, ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression R-HSA-427413, NoRC negatively regulates rRNA expression R-HSA-5250924, B-WICH complex positively regulates rRNA expression R-HSA-5334118, DNA methylation R-HSA-5578749, Transcriptional regulation by small RNAs R-HSA-5617472, Activation of anterior HOX genes in hindbrain development during early embryogenesis R-HSA-5625886, Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3 R-HSA-5689880, Ub-specific processing proteases R-HSA-5693565, Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks R-HSA-5693571, Nonhomologous End-Joining (NHEJ) R-HSA-5693607, Processing of DNA double-strand break ends R-HSA-606279, Deposition of new CENPA-containing nucleosomes at the centromere R-HSA-68616, Assembly of the ORC complex at the origin of replication R-HSA-69473, G2/M DNA damage checkpoint R-HSA-73728, RNA Polymerase I Promoter Opening R-HSA-73772, RNA Polymerase I Promoter Escape R-HSA-8936459, RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function R-HSA-8939236, RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-9018519, Estrogen-dependent gene expression R-HSA-912446, Meiotic recombination R-HSA-9609690, HCMV Early Events R-HSA-9610379, HCMV Late Events R-HSA-9616222, Transcriptional regulation of granulopoiesis R-HSA-9670095, Inhibition of DNA recombination at telomere R-HSA-9710421, Defective pyroptosis R-HSA-977225, Amyloid fiber formation |
SignaLinki | Q8N257 |
SIGNORi | Q8N257 |
Miscellaneous databases
BioGRID-ORCSi | 128312, 51 hits in 1042 CRISPR screens |
ChiTaRSi | HIST3H2BB, human |
GeneWikii | HIST3H2BB |
GenomeRNAii | 128312 |
Pharosi | Q8N257, Tbio |
PROi | PR:Q8N257 |
RNActi | Q8N257, protein |
SOURCEi | Search... |
Gene expression databases
Bgeei | ENSG00000196890, Expressed in ectocervix and 92 other tissues |
Family and domain databases
Gene3Di | 1.10.20.10, 1 hit |
InterProi | View protein in InterPro IPR009072, Histone-fold IPR007125, Histone_H2A/H2B/H3 IPR000558, Histone_H2B |
PANTHERi | PTHR23428, PTHR23428, 1 hit |
Pfami | View protein in Pfam PF00125, Histone, 1 hit |
PRINTSi | PR00621, HISTONEH2B |
SMARTi | View protein in SMART SM00427, H2B, 1 hit |
SUPFAMi | SSF47113, SSF47113, 1 hit |
PROSITEi | View protein in PROSITE PS00357, HISTONE_H2B, 1 hit |
MobiDBi | Search... |
Entry informationi
Entry namei | H2B3B_HUMAN | |
Accessioni | Q8N257Primary (citable) accession number: Q8N257 Secondary accession number(s): A4FU05, Q3ZCP6, Q5TA30 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | August 31, 2004 |
Last sequence update: | January 23, 2007 | |
Last modified: | February 23, 2022 | |
This is version 168 of the entry and version 3 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Chordata Protein Annotation Program | |
Disclaimer | Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. |
Miscellaneousi
Keywords - Technical termi
3D-structure, Direct protein sequencing, Reference proteomeDocuments
- Human chromosome 1
Human chromosome 1: entries, gene names and cross-references to MIM - MIM cross-references
Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot - PDB cross-references
Index of Protein Data Bank (PDB) cross-references - SIMILARITY comments
Index of protein domains and families