UniProtKB - Q8N1F7 (NUP93_HUMAN)
Nuclear pore complex protein Nup93
NUP93
Functioni
GO - Molecular functioni
- structural constituent of nuclear pore Source: UniProtKB
GO - Biological processi
- intracellular transport of virus Source: Reactome
- mRNA export from nucleus Source: Reactome
- nuclear envelope organization Source: UniProtKB
- nuclear pore complex assembly Source: UniProtKB
- poly(A)+ mRNA export from nucleus Source: GO_Central
- positive regulation of SMAD protein signal transduction Source: UniProtKB
- protein import into nucleus Source: GO_Central
- protein sumoylation Source: Reactome
- regulation of cellular response to heat Source: Reactome
- regulation of gene silencing by miRNA Source: Reactome
- regulation of glycolytic process Source: Reactome
- SMAD protein signal transduction Source: UniProtKB
- tRNA export from nucleus Source: Reactome
- viral process Source: Reactome
- viral transcription Source: Reactome
Keywordsi
Biological process | mRNA transport, Protein transport, Translocation, Transport |
Enzyme and pathway databases
PathwayCommonsi | Q8N1F7 |
Reactomei | R-HSA-1169408, ISG15 antiviral mechanism R-HSA-159227, Transport of the SLBP independent Mature mRNA R-HSA-159230, Transport of the SLBP Dependant Mature mRNA R-HSA-159231, Transport of Mature mRNA Derived from an Intronless Transcript R-HSA-159236, Transport of Mature mRNA derived from an Intron-Containing Transcript R-HSA-165054, Rev-mediated nuclear export of HIV RNA R-HSA-168271, Transport of Ribonucleoproteins into the Host Nucleus R-HSA-168276, NS1 Mediated Effects on Host Pathways R-HSA-168325, Viral Messenger RNA Synthesis R-HSA-168333, NEP/NS2 Interacts with the Cellular Export Machinery R-HSA-170822, Regulation of Glucokinase by Glucokinase Regulatory Protein R-HSA-180746, Nuclear import of Rev protein R-HSA-180910, Vpr-mediated nuclear import of PICs R-HSA-191859, snRNP Assembly R-HSA-3108214, SUMOylation of DNA damage response and repair proteins R-HSA-3232142, SUMOylation of ubiquitinylation proteins R-HSA-3301854, Nuclear Pore Complex (NPC) Disassembly R-HSA-3371453, Regulation of HSF1-mediated heat shock response R-HSA-4085377, SUMOylation of SUMOylation proteins R-HSA-4551638, SUMOylation of chromatin organization proteins R-HSA-4570464, SUMOylation of RNA binding proteins R-HSA-4615885, SUMOylation of DNA replication proteins R-HSA-5578749, Transcriptional regulation by small RNAs R-HSA-5619107, Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC) R-HSA-6784531, tRNA processing in the nucleus R-HSA-9609690, HCMV Early Events R-HSA-9610379, HCMV Late Events R-HSA-9615933, Postmitotic nuclear pore complex (NPC) reformation |
Protein family/group databases
TCDBi | 1.I.1.1.3, the nuclear pore complex (npc) family |
Names & Taxonomyi
Protein namesi | Recommended name: Nuclear pore complex protein Nup93Alternative name(s): 93 kDa nucleoporin Nucleoporin Nup93 |
Gene namesi | Name:NUP93 Synonyms:KIAA0095 |
Organismi | Homo sapiens (Human) |
Taxonomic identifieri | 9606 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo |
Proteomesi |
|
Organism-specific databases
HGNCi | HGNC:28958, NUP93 |
MIMi | 614351, gene |
neXtProti | NX_Q8N1F7 |
VEuPathDBi | HostDB:ENSG00000102900.12 |
Subcellular locationi
Nucleus
- Nucleus membrane By similarity; Peripheral membrane protein By similarity
- nuclear pore complex 3 Publications
- Nucleus envelope 2 Publications
Note: Localizes at the nuclear basket and at or near the nuclear entry to the gated channel of the pore.1 Publication
Nucleus
- nuclear envelope Source: UniProtKB
- nuclear membrane Source: UniProtKB
- nuclear periphery Source: UniProtKB
- nuclear pore Source: UniProtKB
Other locations
Keywords - Cellular componenti
Membrane, Nuclear pore complex, NucleusPathology & Biotechi
Involvement in diseasei
Nephrotic syndrome 12 (NPHS12)1 Publication
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Natural variantiVAR_076473 | 388 | R → W in NPHS12; doesnt affect nuclear envelope localization; impairs nuclear pore complex assembly; doesn't abrogate interaction with NUP205; doesn't affect SMAD4 interaction; doesn't affect IPO7 interaction; impairs SMAD4 protein import into nucleus; impairs SMAD4 protein signal transduction. 1 PublicationCorresponds to variant dbSNP:rs145146218EnsemblClinVar. | 1 | |
Natural variantiVAR_076474 | 591 | G → V in NPHS12; doesnt affect nuclear envelope localization; doesn't affect nuclear pore complex assembly; doesn't abrogate interaction with NUP205; abrogates SMAD4 interaction; abrogates IPO7 interaction; impairs SMAD4 protein import into nucleus; impairs SMAD4 protein signal transduction. 1 PublicationCorresponds to variant dbSNP:rs145473779EnsemblClinVar. | 1 | |
Natural variantiVAR_076475 | 629 | Y → C in NPHS12; doesnt affect nuclear envelope localization; doesn't affect nuclear pore complex assembly; doesn't abrogate interaction with NUP205; abrogates SMAD4 interaction; abrogates IPO7 interaction; impairs SMAD4 protein import; impairs SMAD4 protein signal transduction into nucleus;. 1 PublicationCorresponds to variant dbSNP:rs757674160EnsemblClinVar. | 1 |
Keywords - Diseasei
Disease variantOrganism-specific databases
DisGeNETi | 9688 |
MalaCardsi | NUP93 |
MIMi | 616892, phenotype |
OpenTargetsi | ENSG00000102900 |
Orphaneti | 656, Genetic steroid-resistant nephrotic syndrome |
PharmGKBi | PA134912759 |
Miscellaneous databases
Pharosi | Q8N1F7, Tbio |
Genetic variation databases
BioMutai | NUP93 |
DMDMi | 116242684 |
PTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
ChainiPRO_0000124782 | 1 – 819 | Nuclear pore complex protein Nup93Add BLAST | 819 |
Amino acid modifications
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Modified residuei | 49 | PhosphothreonineCombined sources | 1 | |
Modified residuei | 52 | PhosphoserineCombined sources | 1 | |
Modified residuei | 66 | PhosphoserineCombined sources | 1 | |
Modified residuei | 72 | PhosphoserineCombined sources | 1 | |
Modified residuei | 75 | PhosphoserineCombined sources | 1 | |
Modified residuei | 80 | PhosphoserineCombined sources | 1 | |
Modified residuei | 430 | PhosphoserineCombined sources | 1 | |
Modified residuei | 767 | PhosphoserineCombined sources | 1 |
Keywords - PTMi
PhosphoproteinProteomic databases
EPDi | Q8N1F7 |
jPOSTi | Q8N1F7 |
MassIVEi | Q8N1F7 |
MaxQBi | Q8N1F7 |
PaxDbi | Q8N1F7 |
PeptideAtlasi | Q8N1F7 |
PRIDEi | Q8N1F7 |
ProteomicsDBi | 71593 [Q8N1F7-1] 71594 [Q8N1F7-2] |
PTM databases
iPTMneti | Q8N1F7 |
MetOSitei | Q8N1F7 |
PhosphoSitePlusi | Q8N1F7 |
SwissPalmi | Q8N1F7 |
Expressioni
Gene expression databases
Bgeei | ENSG00000102900, Expressed in left lobe of thyroid gland and 227 other tissues |
ExpressionAtlasi | Q8N1F7, baseline and differential |
Genevisiblei | Q8N1F7, HS |
Organism-specific databases
HPAi | ENSG00000102900, Low tissue specificity |
Interactioni
Subunit structurei
Part of the nuclear pore complex (NPC) (PubMed:9348540, PubMed:15229283, PubMed:15703211).
Component of the p62 complex, a complex composed of NUP62 and NUP54 (PubMed:9348540).
Forms a complex with NUP35, NUP155, NUP205 and lamin B; the interaction with NUP35 is direct (PubMed:15703211). Does not interact with TPR (PubMed:12802065, PubMed:15229283).
Interacts with SMAD4 and IPO7; translocates SMAD4 to the nucleus through the NPC upon BMP7 stimulation resulting in activation of SMAD4 signaling (PubMed:26878725).
5 Publications(Microbial infection) Interacts with SARS-CoV translation inhibitor nsp1; this interaction may disrupt nuclear pore function.
1 PublicationBinary interactionsi
Hide detailsQ8N1F7
Protein-protein interaction databases
BioGRIDi | 115041, 141 interactors |
ComplexPortali | CPX-873, Nuclear pore complex |
CORUMi | Q8N1F7 |
DIPi | DIP-44020N |
IntActi | Q8N1F7, 66 interactors |
MINTi | Q8N1F7 |
STRINGi | 9606.ENSP00000310668 |
Miscellaneous databases
RNActi | Q8N1F7, protein |
Family & Domainsi
Sequence similaritiesi
Phylogenomic databases
eggNOGi | KOG2168, Eukaryota |
GeneTreei | ENSGT00390000016353 |
HOGENOMi | CLU_011846_1_0_1 |
InParanoidi | Q8N1F7 |
OrthoDBi | 187731at2759 |
PhylomeDBi | Q8N1F7 |
TreeFami | TF315118 |
Family and domain databases
InterProi | View protein in InterPro IPR007231, Nucleoporin_int_Nup93/Nic96 |
PANTHERi | PTHR11225, PTHR11225, 1 hit |
Pfami | View protein in Pfam PF04097, Nic96, 1 hit |
s (2+)i Sequence
Sequence statusi: Complete.
This entry describes 2 produced by isoformsialternative splicing. AlignAdd to basketThis entry has 2 described isoforms and 13 potential isoforms that are computationally mapped.Show allAlign All
This isoform has been chosen as the sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry. canonicali
10 20 30 40 50
MDTEGFGELL QQAEQLAAET EGISELPHVE RNLQEIQQAG ERLRSRTLTR
60 70 80 90 100
TSQETADVKA SVLLGSRGLD ISHISQRLES LSAATTFEPL EPVKDTDIQG
110 120 130 140 150
FLKNEKDNAL LSAIEESRKR TFGMAEEYHR ESMLVEWEQV KQRILHTLLA
160 170 180 190 200
SGEDALDFTQ ESEPSYISDV GPPGRSSLDN IEMAYARQIY IYNEKIVNGH
210 220 230 240 250
LQPNLVDLCA SVAELDDKSI SDMWTMVKQM TDVLLTPATD ALKNRSSVEV
260 270 280 290 300
RMEFVRQALA YLEQSYKNYT LVTVFGNLHQ AQLGGVPGTY QLVRSFLNIK
310 320 330 340 350
LPAPLPGLQD GEVEGHPVWA LIYYCMRCGD LLAASQVVNR AQHQLGEFKT
360 370 380 390 400
WFQEYMNSKD RRLSPATENK LRLHYRRALR NNTDPYKRAV YCIIGRCDVT
410 420 430 440 450
DNQSEVADKT EDYLWLKLNQ VCFDDDGTSS PQDRLTLSQF QKQLLEDYGE
460 470 480 490 500
SHFTVNQQPF LYFQVLFLTA QFEAAVAFLF RMERLRCHAV HVALVLFELK
510 520 530 540 550
LLLKSSGQSA QLLSHEPGDP PCLRRLNFVR LLMLYTRKFE STDPREALQY
560 570 580 590 600
FYFLRDEKDS QGENMFLRCV SELVIESREF DMILGKLEND GSRKPGVIDK
610 620 630 640 650
FTSDTKPIIN KVASVAENKG LFEEAAKLYD LAKNADKVLE LMNKLLSPVV
660 670 680 690 700
PQISAPQSNK ERLKNMALSI AERYRAQGIS ANKFVDSTFY LLLDLITFFD
710 720 730 740 750
EYHSGHIDRA FDIIERLKLV PLNQESVEER VAAFRNFSDE IRHNLSEVLL
760 770 780 790 800
ATMNILFTQF KRLKGTSPSS SSRPQRVIED RDSQLRSQAR TLITFAGMIP
810
YRTSGDTNAR LVQMEVLMN
Computationally mapped potential isoform sequencesi
There are 13 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basketH3BVG0 | H3BVG0_HUMAN | Nuclear pore complex protein Nup93 | NUP93 | 880 | Annotation score: | ||
H3BRD9 | H3BRD9_HUMAN | Nuclear pore complex protein Nup93 | NUP93 | 140 | Annotation score: | ||
H3BPA9 | H3BPA9_HUMAN | Nuclear pore complex protein Nup93 | NUP93 | 229 | Annotation score: | ||
H3BVE2 | H3BVE2_HUMAN | Nuclear pore complex protein Nup93 | NUP93 | 117 | Annotation score: | ||
H3BP95 | H3BP95_HUMAN | Nuclear pore complex protein Nup93 | NUP93 | 156 | Annotation score: | ||
H3BRI8 | H3BRI8_HUMAN | 93 kDa nucleoporin | NUP93 | 151 | Annotation score: | ||
H3BV15 | H3BV15_HUMAN | 93 kDa nucleoporin | NUP93 | 84 | Annotation score: | ||
H3BM93 | H3BM93_HUMAN | 93 kDa nucleoporin | NUP93 | 178 | Annotation score: | ||
H3BMX0 | H3BMX0_HUMAN | 93 kDa nucleoporin | NUP93 | 125 | Annotation score: | ||
H3BNN5 | H3BNN5_HUMAN | 93 kDa nucleoporin | NUP93 | 132 | Annotation score: | ||
There are more potential isoformsShow all |
Sequence cautioni
Natural variant
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Natural variantiVAR_076473 | 388 | R → W in NPHS12; doesnt affect nuclear envelope localization; impairs nuclear pore complex assembly; doesn't abrogate interaction with NUP205; doesn't affect SMAD4 interaction; doesn't affect IPO7 interaction; impairs SMAD4 protein import into nucleus; impairs SMAD4 protein signal transduction. 1 PublicationCorresponds to variant dbSNP:rs145146218EnsemblClinVar. | 1 | |
Natural variantiVAR_028160 | 509 | S → R1 PublicationCorresponds to variant dbSNP:rs17853288Ensembl. | 1 | |
Natural variantiVAR_076474 | 591 | G → V in NPHS12; doesnt affect nuclear envelope localization; doesn't affect nuclear pore complex assembly; doesn't abrogate interaction with NUP205; abrogates SMAD4 interaction; abrogates IPO7 interaction; impairs SMAD4 protein import into nucleus; impairs SMAD4 protein signal transduction. 1 PublicationCorresponds to variant dbSNP:rs145473779EnsemblClinVar. | 1 | |
Natural variantiVAR_076475 | 629 | Y → C in NPHS12; doesnt affect nuclear envelope localization; doesn't affect nuclear pore complex assembly; doesn't abrogate interaction with NUP205; abrogates SMAD4 interaction; abrogates IPO7 interaction; impairs SMAD4 protein import; impairs SMAD4 protein signal transduction into nucleus;. 1 PublicationCorresponds to variant dbSNP:rs757674160EnsemblClinVar. | 1 |
Alternative sequence
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Alternative sequenceiVSP_043117 | 1 – 123 | Missing in isoform 2. 1 PublicationAdd BLAST | 123 |
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | D42085 mRNA Translation: BAA07680.2 Different initiation. AK294176 mRNA Translation: BAH11689.1 BC034346 mRNA Translation: AAH34346.1 AC012181 Genomic DNA No translation available. AC106779 Genomic DNA No translation available. AC127456 Genomic DNA No translation available. AK056637 mRNA Translation: BAG51770.1 |
CCDSi | CCDS10769.1 [Q8N1F7-1] CCDS55996.1 [Q8N1F7-2] |
RefSeqi | NP_001229724.1, NM_001242795.1 [Q8N1F7-2] NP_001229725.1, NM_001242796.2 [Q8N1F7-2] NP_055484.3, NM_014669.4 [Q8N1F7-1] XP_005256320.1, XM_005256263.3 [Q8N1F7-1] |
Genome annotation databases
Ensembli | ENST00000308159; ENSP00000310668; ENSG00000102900 [Q8N1F7-1] ENST00000542526; ENSP00000440235; ENSG00000102900 [Q8N1F7-2] ENST00000564887; ENSP00000458039; ENSG00000102900 [Q8N1F7-2] |
GeneIDi | 9688 |
KEGGi | hsa:9688 |
UCSCi | uc002eka.4, human [Q8N1F7-1] |
Keywords - Coding sequence diversityi
Alternative splicingSimilar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | D42085 mRNA Translation: BAA07680.2 Different initiation. AK294176 mRNA Translation: BAH11689.1 BC034346 mRNA Translation: AAH34346.1 AC012181 Genomic DNA No translation available. AC106779 Genomic DNA No translation available. AC127456 Genomic DNA No translation available. AK056637 mRNA Translation: BAG51770.1 |
CCDSi | CCDS10769.1 [Q8N1F7-1] CCDS55996.1 [Q8N1F7-2] |
RefSeqi | NP_001229724.1, NM_001242795.1 [Q8N1F7-2] NP_001229725.1, NM_001242796.2 [Q8N1F7-2] NP_055484.3, NM_014669.4 [Q8N1F7-1] XP_005256320.1, XM_005256263.3 [Q8N1F7-1] |
3D structure databases
Select the link destinations: PDBei RCSB PDBi PDBji Links Updated | PDB entry | Method | Resolution (Å) | Chain | Positions | PDBsum |
5IJN | electron microscopy | 21.40 | C/I/O/U | 1-819 | [»] | |
5IJO | electron microscopy | 21.40 | C/I/O/U | 1-819 | [»] | |
SMRi | Q8N1F7 | |||||
ModBasei | Search... | |||||
PDBe-KBi | Search... |
Protein-protein interaction databases
BioGRIDi | 115041, 141 interactors |
ComplexPortali | CPX-873, Nuclear pore complex |
CORUMi | Q8N1F7 |
DIPi | DIP-44020N |
IntActi | Q8N1F7, 66 interactors |
MINTi | Q8N1F7 |
STRINGi | 9606.ENSP00000310668 |
Protein family/group databases
TCDBi | 1.I.1.1.3, the nuclear pore complex (npc) family |
PTM databases
iPTMneti | Q8N1F7 |
MetOSitei | Q8N1F7 |
PhosphoSitePlusi | Q8N1F7 |
SwissPalmi | Q8N1F7 |
Genetic variation databases
BioMutai | NUP93 |
DMDMi | 116242684 |
Proteomic databases
EPDi | Q8N1F7 |
jPOSTi | Q8N1F7 |
MassIVEi | Q8N1F7 |
MaxQBi | Q8N1F7 |
PaxDbi | Q8N1F7 |
PeptideAtlasi | Q8N1F7 |
PRIDEi | Q8N1F7 |
ProteomicsDBi | 71593 [Q8N1F7-1] 71594 [Q8N1F7-2] |
Protocols and materials databases
Antibodypediai | 14851, 121 antibodies |
Genome annotation databases
Ensembli | ENST00000308159; ENSP00000310668; ENSG00000102900 [Q8N1F7-1] ENST00000542526; ENSP00000440235; ENSG00000102900 [Q8N1F7-2] ENST00000564887; ENSP00000458039; ENSG00000102900 [Q8N1F7-2] |
GeneIDi | 9688 |
KEGGi | hsa:9688 |
UCSCi | uc002eka.4, human [Q8N1F7-1] |
Organism-specific databases
CTDi | 9688 |
DisGeNETi | 9688 |
GeneCardsi | NUP93 |
HGNCi | HGNC:28958, NUP93 |
HPAi | ENSG00000102900, Low tissue specificity |
MalaCardsi | NUP93 |
MIMi | 614351, gene 616892, phenotype |
neXtProti | NX_Q8N1F7 |
OpenTargetsi | ENSG00000102900 |
Orphaneti | 656, Genetic steroid-resistant nephrotic syndrome |
PharmGKBi | PA134912759 |
VEuPathDBi | HostDB:ENSG00000102900.12 |
HUGEi | Search... |
GenAtlasi | Search... |
Phylogenomic databases
eggNOGi | KOG2168, Eukaryota |
GeneTreei | ENSGT00390000016353 |
HOGENOMi | CLU_011846_1_0_1 |
InParanoidi | Q8N1F7 |
OrthoDBi | 187731at2759 |
PhylomeDBi | Q8N1F7 |
TreeFami | TF315118 |
Enzyme and pathway databases
PathwayCommonsi | Q8N1F7 |
Reactomei | R-HSA-1169408, ISG15 antiviral mechanism R-HSA-159227, Transport of the SLBP independent Mature mRNA R-HSA-159230, Transport of the SLBP Dependant Mature mRNA R-HSA-159231, Transport of Mature mRNA Derived from an Intronless Transcript R-HSA-159236, Transport of Mature mRNA derived from an Intron-Containing Transcript R-HSA-165054, Rev-mediated nuclear export of HIV RNA R-HSA-168271, Transport of Ribonucleoproteins into the Host Nucleus R-HSA-168276, NS1 Mediated Effects on Host Pathways R-HSA-168325, Viral Messenger RNA Synthesis R-HSA-168333, NEP/NS2 Interacts with the Cellular Export Machinery R-HSA-170822, Regulation of Glucokinase by Glucokinase Regulatory Protein R-HSA-180746, Nuclear import of Rev protein R-HSA-180910, Vpr-mediated nuclear import of PICs R-HSA-191859, snRNP Assembly R-HSA-3108214, SUMOylation of DNA damage response and repair proteins R-HSA-3232142, SUMOylation of ubiquitinylation proteins R-HSA-3301854, Nuclear Pore Complex (NPC) Disassembly R-HSA-3371453, Regulation of HSF1-mediated heat shock response R-HSA-4085377, SUMOylation of SUMOylation proteins R-HSA-4551638, SUMOylation of chromatin organization proteins R-HSA-4570464, SUMOylation of RNA binding proteins R-HSA-4615885, SUMOylation of DNA replication proteins R-HSA-5578749, Transcriptional regulation by small RNAs R-HSA-5619107, Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC) R-HSA-6784531, tRNA processing in the nucleus R-HSA-9609690, HCMV Early Events R-HSA-9610379, HCMV Late Events R-HSA-9615933, Postmitotic nuclear pore complex (NPC) reformation |
Miscellaneous databases
BioGRID-ORCSi | 9688, 714 hits in 880 CRISPR screens |
ChiTaRSi | NUP93, human |
GeneWikii | NUP93 |
GenomeRNAii | 9688 |
Pharosi | Q8N1F7, Tbio |
PROi | PR:Q8N1F7 |
RNActi | Q8N1F7, protein |
SOURCEi | Search... |
Gene expression databases
Bgeei | ENSG00000102900, Expressed in left lobe of thyroid gland and 227 other tissues |
ExpressionAtlasi | Q8N1F7, baseline and differential |
Genevisiblei | Q8N1F7, HS |
Family and domain databases
InterProi | View protein in InterPro IPR007231, Nucleoporin_int_Nup93/Nic96 |
PANTHERi | PTHR11225, PTHR11225, 1 hit |
Pfami | View protein in Pfam PF04097, Nic96, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | NUP93_HUMAN | |
Accessioni | Q8N1F7Primary (citable) accession number: Q8N1F7 Secondary accession number(s): B3KPQ8, Q14705 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | January 16, 2004 |
Last sequence update: | October 17, 2006 | |
Last modified: | February 10, 2021 | |
This is version 171 of the entry and version 2 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Chordata Protein Annotation Program | |
Disclaimer | Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. |
Miscellaneousi
Keywords - Technical termi
3D-structure, Reference proteomeDocuments
- Human variants curated from literature reports
Index of human variants curated from literature reports - MIM cross-references
Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot - PDB cross-references
Index of Protein Data Bank (PDB) cross-references - SIMILARITY comments
Index of protein domains and families - Human chromosome 16
Human chromosome 16: entries, gene names and cross-references to MIM - Human entries with genetic variants
List of human entries with genetic variants