Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
We will be switching to the new UniProt website on Tuesday, June 28. Please explore and share your feedback. Take me to UniProt BETA

UniProtKB - Q8N0Y7 (PGAM4_HUMAN)

Entry version 157 (25 May 2022)
Sequence version 1 (01 Oct 2002)
Previous versions | rss
Add a publicationFeedback
Protein

Probable phosphoglycerate mutase 4

Gene

PGAM4

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:4 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>-Protein inferred from homologyi <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Miscellaneous

This is the product of a processed gene created by retroposition from mRNA of an expressed gene. This gene seems to be expressed.

<p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">Function</a> section describes the catalytic activity of an enzyme, i.e. a chemical reaction that the enzyme catalyzes.<p><a href='/help/catalytic_activity' target='_top'>More...</a></p>Catalytic activityi

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">Function</a> section is used for enzymes and indicates the residues directly involved in catalysis.<p><a href='/help/act_site' target='_top'>More...</a></p>Active sitei11Tele-phosphohistidine intermediateBy similarity1
<p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">Function</a> section describes the interaction between a single amino acid and another chemical entity. Priority is given to the annotation of physiological ligands.<p><a href='/help/binding' target='_top'>More...</a></p>Binding sitei62SubstrateBy similarity1
Active sitei89Proton donor/acceptorBy similarity1
Binding sitei100SubstrateBy similarity1
<p>This subsection describes interesting single amino acid sites on the sequence that are not defined in any other subsection. This subsection can be displayed in different sections ('Function', 'PTM / Processing', 'Pathology and Biotech') according to its content.<p><a href='/help/site' target='_top'>More...</a></p>Sitei186Transition state stabilizerBy similarity1

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

Complete GO annotation on QuickGO ...

GO - Biological processi

Complete GO annotation on QuickGO ...

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionHydrolase, Isomerase
Biological processGlycolysis

Enzyme and pathway databases

Pathway Commons web resource for biological pathway data

More...PathwayCommonsi		Q8N0Y7

SignaLink: a signaling pathway resource with multi-layered regulatory networks

More...SignaLinki		Q8N0Y7

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Probable phosphoglycerate mutase 4 (EC:5.4.2.11By similarity, EC:5.4.2.4By similarity)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:PGAM4
Synonyms:PGAM3
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome X

Organism-specific databases

Human Gene Nomenclature Database

More...HGNCi		HGNC:21731, PGAM4

Online Mendelian Inheritance in Man (OMIM)

More...MIMi		300567, gene

neXtProt; the human protein knowledge platform

More...neXtProti		NX_Q8N0Y7

Eukaryotic Pathogen, Vector and Host Database Resources

More...VEuPathDBi		HostDB:ENSG00000226784

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

DisGeNET

More...DisGeNETi		441531

Open Targets

More...OpenTargetsi		ENSG00000226784

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...PharmGKBi		PA142671183

Miscellaneous databases

Pharos NIH Druggable Genome Knowledgebase

More...Pharosi		Q8N0Y7, Tbio

Genetic variation databases

BioMuta curated single-nucleotide variation and disease association database

More...BioMutai		PGAM4

Domain mapping of disease mutations (DMDM)

More...DMDMi		26006838

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00001798321 – 254Probable phosphoglycerate mutase 4Add BLAST254

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei14PhosphoserineBy similarity1
Modified residuei23PhosphoserineBy similarity1
Modified residuei26PhosphotyrosineBy similarity1
Modified residuei31PhosphoserineBy similarity1
Modified residuei106N6-acetyllysineBy similarity1
Modified residuei118PhosphoserineBy similarity1
Modified residuei251N6-acetyllysine; alternateBy similarity1
Modified residuei251N6-succinyllysine; alternateBy similarity1
Modified residuei253N6-acetyllysineBy similarity1
Modified residuei254N6-acetyllysineBy similarity1

Keywords - PTMi

Acetylation, Phosphoprotein

Proteomic databases

Encyclopedia of Proteome Dynamics

More...EPDi		Q8N0Y7

jPOST - Japan Proteome Standard Repository/Database

More...jPOSTi		Q8N0Y7

MassIVE - Mass Spectrometry Interactive Virtual Environment

More...MassIVEi		Q8N0Y7

MaxQB - The MaxQuant DataBase

More...MaxQBi		Q8N0Y7

PaxDb, a database of protein abundance averages across all three domains of life

More...PaxDbi		Q8N0Y7

PeptideAtlas

More...PeptideAtlasi		Q8N0Y7

PRoteomics IDEntifications database

More...PRIDEi		Q8N0Y7

ProteomicsDB: a multi-organism proteome resource

More...ProteomicsDBi		71490

PTM databases

DEPOD human dephosphorylation database

More...DEPODi		PGAM4

GlyGen: Computational and Informatics Resources for Glycoscience

More...GlyGeni		Q8N0Y7, 1 site, 1 O-linked glycan (1 site)

iPTMnet integrated resource for PTMs in systems biology context

More...iPTMneti		Q8N0Y7

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...PhosphoSitePlusi		Q8N0Y7

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...Bgeei		ENSG00000226784, Expressed in temporal lobe and 71 other tissues

Genevisible search portal to normalized and curated expression data from Genevestigator

More...Genevisiblei		Q8N0Y7, HS

Organism-specific databases

Human Protein Atlas

More...HPAi		ENSG00000226784, Not detected

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGRID)

More...BioGRIDi		137555, 36 interactors

Protein interaction database and analysis system

More...IntActi		Q8N0Y7, 2 interactors

STRING: functional protein association networks

More...STRINGi		9606.ENSP00000412189

Miscellaneous databases

RNAct, Protein-RNA interaction predictions for model organisms.

More...RNActi		Q8N0Y7, protein

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

AlphaFold Protein Structure Database

More...AlphaFoldDBi		Q8N0Y7

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...SMRi		Q8N0Y7

Database of comparative protein structure models

More...ModBasei		Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni10 – 17Substrate bindingBy similarity8
Regioni23 – 24Substrate bindingBy similarity2
Regioni89 – 92Substrate bindingBy similarity4
Regioni116 – 117Substrate bindingBy similarity2
Regioni187 – 188Substrate bindingBy similarity2

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.Curated

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...eggNOGi		KOG0235, Eukaryota

Ensembl GeneTree

More...GeneTreei		ENSGT00950000182926

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...HOGENOMi		CLU_033323_1_1_1

InParanoid: Eukaryotic Ortholog Groups

More...InParanoidi		Q8N0Y7

Identification of Orthologs from Complete Genome Data

More...OMAi		DHDYYAI

Database for complete collections of gene phylogenies

More...PhylomeDBi		Q8N0Y7

TreeFam database of animal gene trees

More...TreeFami		TF300007

Family and domain databases

Conserved Domains Database

More...CDDi		cd07067, HP_PGM_like, 1 hit

Gene3D Structural and Functional Annotation of Protein Families

More...Gene3Di		3.40.50.1240, 1 hit

HAMAP database of protein families

More...HAMAPi		MF_01039, PGAM_GpmA, 1 hit

Integrated resource of protein families, domains and functional sites

More...InterProi		View protein in InterPro
IPR013078, His_Pase_superF_clade-1
IPR029033, His_PPase_superfam
IPR001345, PG/BPGM_mutase_AS
IPR005952, Phosphogly_mut1

The PANTHER Classification System

More...PANTHERi		PTHR11931, PTHR11931, 1 hit

Pfam protein domain database

More...Pfami		View protein in Pfam
PF00300, His_Phos_1, 2 hits

Simple Modular Architecture Research Tool; a protein domain database

More...SMARTi		View protein in SMART
SM00855, PGAM, 1 hit

Superfamily database of structural and functional annotation

More...SUPFAMi		SSF53254, SSF53254, 1 hit

TIGRFAMs; a protein family database

More...TIGRFAMsi		TIGR01258, pgm_1, 1 hit

PROSITE; a protein domain and family database

More...PROSITEi		View protein in PROSITE
PS00175, PG_MUTASE, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

Q8N0Y7-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MAAYKLVLIR HGESTWNLEN RFSCWYDADL SPAGHEEAKR GGQALRDAGY 
        60         70         80         90        100
EFDICLTSVQ KRVIRTLWTV LDAIDQMWLP VVRTWRLNER HYGGLTGLNK 
       110        120        130        140        150
AETAAKHGEA QVKIWRRSYD VPPPPMEPDH PFYSNISKDR RYADLTEDQL 
       160        170        180        190        200
PSYESPKDTI ARALPFWNEE IVPQIKEGKR VLIAAHGNSL QGIAKHVEGL 
       210        220        230        240        250
SEEAIMELNL PTGIPIVYEL DKNLKPIKPM QFLGDEETVC KAIEAVAAQG 

KAKK
Length:254
Mass (Da):28,777
Last modified:October 1, 2002 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iBB589CDEAAC2E706
GO

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section describes natural variant(s) of the protein sequence.<p><a href='/help/variant' target='_top'>More...</a></p>Natural variantiVAR_01435540R → C1 PublicationCorresponds to variant dbSNP:rs782408548Ensembl.1
Natural variantiVAR_01435690R → Q1 PublicationCorresponds to variant dbSNP:rs5959129Ensembl.1
Natural variantiVAR_014357175I → T1 Publication1

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...EMBLi

GenBank nucleotide sequence database

More...GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...DDBJi
Links Updated
AF465731 Genomic DNA Translation: AAM27282.1
AF465732 Genomic DNA Translation: AAM27283.1
AF465733 Genomic DNA Translation: AAM27284.1
AF465734 Genomic DNA Translation: AAM27285.1
AF465735 Genomic DNA Translation: AAM27286.1
AF465736 Genomic DNA Translation: AAM27287.1
AF465737 Genomic DNA Translation: AAM27288.1
AF465738 Genomic DNA Translation: AAM27289.1
AF465739 Genomic DNA Translation: AAM27290.1
AF465740 Genomic DNA Translation: AAM27291.1
AF465741 Genomic DNA Translation: AAM27292.1
AF465742 Genomic DNA Translation: AAM27293.1
AF465743 Genomic DNA Translation: AAM27294.1
AF465744 Genomic DNA Translation: AAM27295.1
AF465745 Genomic DNA Translation: AAM27296.1
DQ120647 Genomic DNA Translation: ABB92432.1
AL772330 Genomic DNA No translation available.

The Consensus CDS (CCDS) project

More...CCDSi		CCDS35338.1

NCBI Reference Sequences

More...RefSeqi		NP_001025062.1, NM_001029891.2

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...Ensembli		ENST00000458128.3; ENSP00000412189.1; ENSG00000226784.3

Database of genes from NCBI RefSeq genomes

More...GeneIDi		441531

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...KEGGi		hsa:441531

Matched Annotation from NCBI and EMBL-EBI (MANE) - Phase one

More...MANE-Selecti		ENST00000458128.3; ENSP00000412189.1; NM_001029891.3; NP_001025062.1

UCSC genome browser

More...UCSCi		uc004ecy.2, human

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF465731 Genomic DNA Translation: AAM27282.1
AF465732 Genomic DNA Translation: AAM27283.1
AF465733 Genomic DNA Translation: AAM27284.1
AF465734 Genomic DNA Translation: AAM27285.1
AF465735 Genomic DNA Translation: AAM27286.1
AF465736 Genomic DNA Translation: AAM27287.1
AF465737 Genomic DNA Translation: AAM27288.1
AF465738 Genomic DNA Translation: AAM27289.1
AF465739 Genomic DNA Translation: AAM27290.1
AF465740 Genomic DNA Translation: AAM27291.1
AF465741 Genomic DNA Translation: AAM27292.1
AF465742 Genomic DNA Translation: AAM27293.1
AF465743 Genomic DNA Translation: AAM27294.1
AF465744 Genomic DNA Translation: AAM27295.1
AF465745 Genomic DNA Translation: AAM27296.1
DQ120647 Genomic DNA Translation: ABB92432.1
AL772330 Genomic DNA No translation available.
CCDSiCCDS35338.1
RefSeqiNP_001025062.1, NM_001029891.2

3D structure databases

AlphaFoldDBiQ8N0Y7
SMRiQ8N0Y7
ModBaseiSearch...

Protein-protein interaction databases

BioGRIDi137555, 36 interactors
IntActiQ8N0Y7, 2 interactors
STRINGi9606.ENSP00000412189

PTM databases

DEPODiPGAM4
GlyGeniQ8N0Y7, 1 site, 1 O-linked glycan (1 site)
iPTMnetiQ8N0Y7
PhosphoSitePlusiQ8N0Y7

Genetic variation databases

BioMutaiPGAM4
DMDMi26006838

Proteomic databases

EPDiQ8N0Y7
jPOSTiQ8N0Y7
MassIVEiQ8N0Y7
MaxQBiQ8N0Y7
PaxDbiQ8N0Y7
PeptideAtlasiQ8N0Y7
PRIDEiQ8N0Y7
ProteomicsDBi71490

Protocols and materials databases

Antibodypedia a portal for validated antibodies

More...Antibodypediai		67001, 99 antibodies from 14 providers

The DNASU plasmid repository

More...DNASUi		441531

Genome annotation databases

EnsembliENST00000458128.3; ENSP00000412189.1; ENSG00000226784.3
GeneIDi441531
KEGGihsa:441531
MANE-SelectiENST00000458128.3; ENSP00000412189.1; NM_001029891.3; NP_001025062.1
UCSCiuc004ecy.2, human

Organism-specific databases

Comparative Toxicogenomics Database

More...CTDi		441531
DisGeNETi441531

GeneCards: human genes, protein and diseases

More...GeneCardsi		PGAM4
HGNCiHGNC:21731, PGAM4
HPAiENSG00000226784, Not detected
MIMi300567, gene
neXtProtiNX_Q8N0Y7
OpenTargetsiENSG00000226784
PharmGKBiPA142671183
VEuPathDBiHostDB:ENSG00000226784

GenAtlas: human gene database

More...GenAtlasi		Search...

Phylogenomic databases

eggNOGiKOG0235, Eukaryota
GeneTreeiENSGT00950000182926
HOGENOMiCLU_033323_1_1_1
InParanoidiQ8N0Y7
OMAiDHDYYAI
PhylomeDBiQ8N0Y7
TreeFamiTF300007

Enzyme and pathway databases

PathwayCommonsiQ8N0Y7
SignaLinkiQ8N0Y7

Miscellaneous databases

BioGRID ORCS database of CRISPR phenotype screens

More...BioGRID-ORCSi		441531, 315 hits in 626 CRISPR screens

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...GenomeRNAii		441531
PharosiQ8N0Y7, Tbio

Protein Ontology

More...PROi		PR:Q8N0Y7
RNActiQ8N0Y7, protein

The Stanford Online Universal Resource for Clones and ESTs

More...SOURCEi		Search...

Gene expression databases

BgeeiENSG00000226784, Expressed in temporal lobe and 71 other tissues
GenevisibleiQ8N0Y7, HS

Family and domain databases

CDDicd07067, HP_PGM_like, 1 hit
Gene3Di3.40.50.1240, 1 hit
HAMAPiMF_01039, PGAM_GpmA, 1 hit
InterProiView protein in InterPro
IPR013078, His_Pase_superF_clade-1
IPR029033, His_PPase_superfam
IPR001345, PG/BPGM_mutase_AS
IPR005952, Phosphogly_mut1
PANTHERiPTHR11931, PTHR11931, 1 hit
PfamiView protein in Pfam
PF00300, His_Phos_1, 2 hits
SMARTiView protein in SMART
SM00855, PGAM, 1 hit
SUPFAMiSSF53254, SSF53254, 1 hit
TIGRFAMsiTIGR01258, pgm_1, 1 hit
PROSITEiView protein in PROSITE
PS00175, PG_MUTASE, 1 hit

MobiDB: a database of protein disorder and mobility annotations

More...MobiDBi		Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiPGAM4_HUMAN
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q8N0Y7
Secondary accession number(s): Q5JPN2
, Q8NI24, Q8NI25, Q8NI26
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: November 28, 2002
Last sequence update: October 1, 2002
Last modified: May 25, 2022
This is version 157 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. Human chromosome X
    Human chromosome X: entries, gene names and cross-references to MIM
  2. Human entries with genetic variants
    List of human entries with genetic variants
  3. Human variants curated from literature reports
    Index of human variants curated from literature reports
  4. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
  5. SIMILARITY comments
    Index of protein domains and families
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.

Do not show this banner again