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Entry version 139 (02 Dec 2020)
Sequence version 3 (06 Mar 2007)
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Protein

Putative ribosome-binding factor A, mitochondrial

Gene

RBFA

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Biological processrRNA processing

Enzyme and pathway databases

Pathway Commons web resource for biological pathway data

More...
PathwayCommonsi
Q8N0V3

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Putative ribosome-binding factor A, mitochondrial
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:RBFA
Synonyms:C18orf22
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 18

Organism-specific databases

Eukaryotic Pathogen and Host Database Resources

More...
EuPathDBi
HostDB:ENSG00000101546.12

Human Gene Nomenclature Database

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HGNCi
HGNC:26120, RBFA

neXtProt; the human protein knowledge platform

More...
neXtProti
NX_Q8N0V3

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

Keywords - Cellular componenti

Mitochondrion

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

DisGeNET

More...
DisGeNETi
79863

Open Targets

More...
OpenTargetsi
ENSG00000101546

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...
PharmGKBi
PA134885774

Miscellaneous databases

Pharos NIH Druggable Genome Knowledgebase

More...
Pharosi
Q8N0V3, Tbio

Polymorphism and mutation databases

BioMuta curated single-nucleotide variation and disease association database

More...
BioMutai
RBFA

Domain mapping of disease mutations (DMDM)

More...
DMDMi
146334837

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a transit peptide.<p><a href='/help/transit' target='_top'>More...</a></p>Transit peptidei1 – 41MitochondrionSequence analysisAdd BLAST41
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_000003022642 – 343Putative ribosome-binding factor A, mitochondrialAdd BLAST302

Proteomic databases

Encyclopedia of Proteome Dynamics

More...
EPDi
Q8N0V3

jPOST - Japan Proteome Standard Repository/Database

More...
jPOSTi
Q8N0V3

MassIVE - Mass Spectrometry Interactive Virtual Environment

More...
MassIVEi
Q8N0V3

MaxQB - The MaxQuant DataBase

More...
MaxQBi
Q8N0V3

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q8N0V3

PeptideAtlas

More...
PeptideAtlasi
Q8N0V3

PRoteomics IDEntifications database

More...
PRIDEi
Q8N0V3

ProteomicsDB: a multi-organism proteome resource

More...
ProteomicsDBi
71465 [Q8N0V3-1]
71466 [Q8N0V3-2]

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
Q8N0V3

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
Q8N0V3

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSG00000101546, Expressed in quadriceps femoris and 210 other tissues

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
Q8N0V3, HS

Organism-specific databases

Human Protein Atlas

More...
HPAi
ENSG00000101546, Low tissue specificity

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the '<a href="http://www.uniprot.org/help/interaction%5Fsection">Interaction</a>' section provides information about binary protein-protein interactions. The data presented in this section are a quality-filtered subset of binary interactions automatically derived from the <a href="https://www.ebi.ac.uk/intact/">IntAct database</a>. It is updated at every <a href="http://www.uniprot.org/help/synchronization">UniProt release</a>.<p><a href='/help/binary_interactions' target='_top'>More...</a></p>Binary interactionsi

Hide details

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGRID)

More...
BioGRIDi
122951, 43 interactors

Protein interaction database and analysis system

More...
IntActi
Q8N0V3, 38 interactors

Molecular INTeraction database

More...
MINTi
Q8N0V3

STRING: functional protein association networks

More...
STRINGi
9606.ENSP00000305696

Miscellaneous databases

RNAct, Protein-RNA interaction predictions for model organisms.

More...
RNActi
Q8N0V3, protein

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

Secondary structure

1343
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
Q8N0V3

Database of comparative protein structure models

More...
ModBasei
Search...

Protein Data Bank in Europe - Knowledge Base

More...
PDBe-KBi
Search...

Miscellaneous databases

Relative evolutionary importance of amino acids within a protein sequence

More...
EvolutionaryTracei
Q8N0V3

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the RbfA family.Curated

Keywords - Domaini

Transit peptide

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG4700, Eukaryota

Ensembl GeneTree

More...
GeneTreei
ENSGT00390000011362

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
CLU_067827_0_0_1

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q8N0V3

Identification of Orthologs from Complete Genome Data

More...
OMAi
VCGINHE

Database of Orthologous Groups

More...
OrthoDBi
1420734at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q8N0V3

TreeFam database of animal gene trees

More...
TreeFami
TF328637

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
3.30.300.20, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR015946, KH_dom-like_a/b
IPR000238, RbfA
IPR023799, RbfA_dom_sf
IPR039212, RBFA_mitochondrial
IPR020053, Ribosome-bd_factorA_CS

The PANTHER Classification System

More...
PANTHERi
PTHR14725, PTHR14725, 1 hit

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF02033, RBFA, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF89919, SSF89919, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS01319, RBFA, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequences (2)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is in its mature form or if it represents the precursor.<p><a href='/help/sequence_processing' target='_top'>More...</a></p>Sequence processingi: The displayed sequence is further processed into a mature form.

This entry describes 2 <p>This subsection of the 'Sequence' section lists the alternative protein sequences (isoforms) that can be generated from the same gene by a single or by the combination of up to four biological events (alternative promoter usage, alternative splicing, alternative initiation and ribosomal frameshifting). Additionally, this section gives relevant information on each alternative protein isoform. This section is only present in reviewed entries, i.e. in UniProtKB/Swiss-Prot.<p><a href='/help/alternative_products' target='_top'>More...</a></p> isoformsi produced by alternative splicing. AlignAdd to basket
Isoform 1 (identifier: Q8N0V3-1) [UniParc]FASTAAdd to basket
Also known as: p38

This isoform has been chosen as the <div> <p><b>What is the canonical sequence?</b><p><a href='/help/canonical_and_isoforms' target='_top'>More...</a></p>canonicali sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide
        10         20         30         40         50
MWAAAGGLWR SRAGLRALFR SRDAALFPGC ERGLHCSAVS CKNWLKKFAS
60 70 80 90 100
KTKKKVWYES PSLGSHSTYK PSKLEFLMRS TSKKTRKEDH ARLRALNGLL
110 120 130 140 150
YKALTDLLCT PEVSQELYDL NVELSKVSLT PDFSACRAYW KTTLSAEQNA
160 170 180 190 200
HMEAVLQRSA AHMRHLLMSQ QTLRNVPPIV FVQDKGNAAL AELDQLLAVA
210 220 230 240 250
DFGPRDERDN FVQNDFRDPD APQPCGTTEP TTSSSLCGID HEALNKQIME
260 270 280 290 300
YKRRKDKGLG GLVWQGQVAE LTTQMKKGRK RAKPRLEQDS SLKSYLSGEE
310 320 330 340
VEDDLDLVGA PEYECYAPDT EELEAERGGG RTEDGHSCGA SRE
Length:343
Mass (Da):38,359
Last modified:March 6, 2007 - v3
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iE8BE374855BEF403
GO
Isoform 2 (identifier: Q8N0V3-2) [UniParc]FASTAAdd to basket
Also known as: p27

The sequence of this isoform differs from the canonical sequence as follows:
     164-242: RHLLMSQQTL...SSSLCGIDHE → SLISYWQSQT...AWCGRGRWLS
     243-343: Missing.

Show »
Length:242
Mass (Da):27,062
Checksum:i4918C96F48B5CF45
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti326E → G in AAM20740 (Ref. 1) Curated1

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section describes natural variant(s) of the protein sequence.<p><a href='/help/variant' target='_top'>More...</a></p>Natural variantiVAR_023233122V → M. Corresponds to variant dbSNP:rs748338Ensembl.1
Natural variantiVAR_023234245N → H1 PublicationCorresponds to variant dbSNP:rs3744872Ensembl.1
Natural variantiVAR_023235276K → Q2 PublicationsCorresponds to variant dbSNP:rs3744873Ensembl.1

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section describes the sequence of naturally occurring alternative protein isoform(s). The changes in the amino acid sequence may be due to alternative splicing, alternative promoter usage, alternative initiation, or ribosomal frameshifting.<p><a href='/help/var_seq' target='_top'>More...</a></p>Alternative sequenceiVSP_015118164 – 242RHLLM…GIDHE → SLISYWQSQTLDPGMKETTL YKMISGTLMPHNPAAPQSRP QAPVCVGSIMRRSTSRLWST KGGKIKGSGAWCGRGRWLS in isoform 2. 1 PublicationAdd BLAST79
Alternative sequenceiVSP_015119243 – 343Missing in isoform 2. 1 PublicationAdd BLAST101

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AF261073 mRNA Translation: AAM20740.1
AF439745 mRNA Translation: AAL32051.1
AK024825 mRNA Translation: BAB15022.1
BC014195 mRNA Translation: AAH14195.1
BC057772 mRNA Translation: AAH57772.1

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS12021.1 [Q8N0V3-1]
CCDS54194.1 [Q8N0V3-2]

NCBI Reference Sequences

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RefSeqi
NP_001165438.1, NM_001171967.1 [Q8N0V3-2]
NP_079081.2, NM_024805.2 [Q8N0V3-1]

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENST00000262197; ENSP00000262197; ENSG00000101546 [Q8N0V3-2]
ENST00000306735; ENSP00000305696; ENSG00000101546 [Q8N0V3-1]

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
79863

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
hsa:79863

UCSC genome browser

More...
UCSCi
uc002lns.4, human [Q8N0V3-1]

Keywords - Coding sequence diversityi

Alternative splicing, Polymorphism

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF261073 mRNA Translation: AAM20740.1
AF439745 mRNA Translation: AAL32051.1
AK024825 mRNA Translation: BAB15022.1
BC014195 mRNA Translation: AAH14195.1
BC057772 mRNA Translation: AAH57772.1
CCDSiCCDS12021.1 [Q8N0V3-1]
CCDS54194.1 [Q8N0V3-2]
RefSeqiNP_001165438.1, NM_001171967.1 [Q8N0V3-2]
NP_079081.2, NM_024805.2 [Q8N0V3-1]

3D structure databases

Select the link destinations:

Protein Data Bank Europe

More...
PDBei

Protein Data Bank RCSB

More...
RCSB PDBi

Protein Data Bank Japan

More...
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
2E7GNMR-A86-201[»]
SMRiQ8N0V3
ModBaseiSearch...
PDBe-KBiSearch...

Protein-protein interaction databases

BioGRIDi122951, 43 interactors
IntActiQ8N0V3, 38 interactors
MINTiQ8N0V3
STRINGi9606.ENSP00000305696

PTM databases

iPTMnetiQ8N0V3
PhosphoSitePlusiQ8N0V3

Polymorphism and mutation databases

BioMutaiRBFA
DMDMi146334837

Proteomic databases

EPDiQ8N0V3
jPOSTiQ8N0V3
MassIVEiQ8N0V3
MaxQBiQ8N0V3
PaxDbiQ8N0V3
PeptideAtlasiQ8N0V3
PRIDEiQ8N0V3
ProteomicsDBi71465 [Q8N0V3-1]
71466 [Q8N0V3-2]

Protocols and materials databases

Antibodypedia a portal for validated antibodies

More...
Antibodypediai
23520, 78 antibodies

The DNASU plasmid repository

More...
DNASUi
79863

Genome annotation databases

EnsembliENST00000262197; ENSP00000262197; ENSG00000101546 [Q8N0V3-2]
ENST00000306735; ENSP00000305696; ENSG00000101546 [Q8N0V3-1]
GeneIDi79863
KEGGihsa:79863
UCSCiuc002lns.4, human [Q8N0V3-1]

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
79863
DisGeNETi79863
EuPathDBiHostDB:ENSG00000101546.12

GeneCards: human genes, protein and diseases

More...
GeneCardsi
RBFA
HGNCiHGNC:26120, RBFA
HPAiENSG00000101546, Low tissue specificity
neXtProtiNX_Q8N0V3
OpenTargetsiENSG00000101546
PharmGKBiPA134885774

GenAtlas: human gene database

More...
GenAtlasi
Search...

Phylogenomic databases

eggNOGiKOG4700, Eukaryota
GeneTreeiENSGT00390000011362
HOGENOMiCLU_067827_0_0_1
InParanoidiQ8N0V3
OMAiVCGINHE
OrthoDBi1420734at2759
PhylomeDBiQ8N0V3
TreeFamiTF328637

Enzyme and pathway databases

PathwayCommonsiQ8N0V3

Miscellaneous databases

BioGRID ORCS database of CRISPR phenotype screens

More...
BioGRID-ORCSi
79863, 70 hits in 846 CRISPR screens

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...
ChiTaRSi
RBFA, human
EvolutionaryTraceiQ8N0V3

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...
GenomeRNAii
79863
PharosiQ8N0V3, Tbio

Protein Ontology

More...
PROi
PR:Q8N0V3
RNActiQ8N0V3, protein

Gene expression databases

BgeeiENSG00000101546, Expressed in quadriceps femoris and 210 other tissues
GenevisibleiQ8N0V3, HS

Family and domain databases

Gene3Di3.30.300.20, 1 hit
InterProiView protein in InterPro
IPR015946, KH_dom-like_a/b
IPR000238, RbfA
IPR023799, RbfA_dom_sf
IPR039212, RBFA_mitochondrial
IPR020053, Ribosome-bd_factorA_CS
PANTHERiPTHR14725, PTHR14725, 1 hit
PfamiView protein in Pfam
PF02033, RBFA, 1 hit
SUPFAMiSSF89919, SSF89919, 1 hit
PROSITEiView protein in PROSITE
PS01319, RBFA, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiRBFA_HUMAN
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q8N0V3
Secondary accession number(s): Q6PF07, Q8WZ65, Q9H776
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: August 16, 2005
Last sequence update: March 6, 2007
Last modified: December 2, 2020
This is version 139 of the entry and version 3 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

3D-structure, Reference proteome

Documents

  1. Human polymorphisms and disease mutations
    Index of human polymorphisms and disease mutations
  2. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  3. SIMILARITY comments
    Index of protein domains and families
  4. Human chromosome 18
    Human chromosome 18: entries, gene names and cross-references to MIM
  5. Human entries with polymorphisms or disease mutations
    List of human entries with polymorphisms or disease mutations
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