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Entry version 121 (07 Apr 2021)
Sequence version 4 (14 May 2014)
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Protein

Ribosomal biogenesis factor

Gene

RBIS

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:4 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Trans-acting factor in ribosome biogenesis required for efficient 40S and 60S subunit production.1 Publication

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Biological processi

Enzyme and pathway databases

Pathway Commons web resource for biological pathway data

More...
PathwayCommonsi
Q8N0T1

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Ribosomal biogenesis factorCurated
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:RBISImported
Synonyms:C8orf59
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 8

Organism-specific databases

Human Gene Nomenclature Database

More...
HGNCi
HGNC:32235, RBIS

neXtProt; the human protein knowledge platform

More...
neXtProti
NX_Q8N0T1

Eukaryotic Pathogen, Vector and Host Database Resources

More...
VEuPathDBi
HostDB:ENSG00000176731.11

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Cellular componenti

Nucleus

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

Open Targets

More...
OpenTargetsi
ENSG00000176731

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...
PharmGKBi
PA142672322

Miscellaneous databases

Pharos NIH Druggable Genome Knowledgebase

More...
Pharosi
Q8N0T1, Tdark

Genetic variation databases

BioMuta curated single-nucleotide variation and disease association database

More...
BioMutai
C8orf59

Domain mapping of disease mutations (DMDM)

More...
DMDMi
519668681

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00003246041 – 100Ribosomal biogenesis factorAdd BLAST100

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei19PhosphoserineCombined sources1
Modified residuei21N6-acetyllysineCombined sources1
Modified residuei69PhosphoserineCombined sources1

Keywords - PTMi

Acetylation, Phosphoprotein

Proteomic databases

Encyclopedia of Proteome Dynamics

More...
EPDi
Q8N0T1

jPOST - Japan Proteome Standard Repository/Database

More...
jPOSTi
Q8N0T1

MassIVE - Mass Spectrometry Interactive Virtual Environment

More...
MassIVEi
Q8N0T1

MaxQB - The MaxQuant DataBase

More...
MaxQBi
Q8N0T1

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q8N0T1

PeptideAtlas

More...
PeptideAtlasi
Q8N0T1

PRoteomics IDEntifications database

More...
PRIDEi
Q8N0T1

ProteomicsDB: a multi-organism proteome resource

More...
ProteomicsDBi
15478
71453 [Q8N0T1-1]
71454 [Q8N0T1-2]

Consortium for Top Down Proteomics

More...
TopDownProteomicsi
Q8N0T1-1 [Q8N0T1-1]

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
Q8N0T1

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
Q8N0T1

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSG00000176731, Expressed in metanephros and 215 other tissues

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
Q8N0T1, baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
Q8N0T1, HS

Organism-specific databases

Human Protein Atlas

More...
HPAi
ENSG00000176731, Low tissue specificity

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction%5Fsection">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function%5Fsection">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

Associates with the pre-60S ribosomal particles.

1 Publication

<p>This subsection of the '<a href="http://www.uniprot.org/help/interaction%5Fsection">Interaction</a>' section provides information about binary protein-protein interactions. The data presented in this section are a quality-filtered subset of binary interactions automatically derived from the <a href="https://www.ebi.ac.uk/intact/">IntAct database</a>. It is updated at every <a href="http://www.uniprot.org/help/synchronization">UniProt release</a>.<p><a href='/help/binary_interactions' target='_top'>More...</a></p>Binary interactionsi

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGRID)

More...
BioGRIDi
135095, 6 interactors

Protein interaction database and analysis system

More...
IntActi
Q8N0T1, 3 interactors

STRING: functional protein association networks

More...
STRINGi
9606.ENSP00000484492

Miscellaneous databases

RNAct, Protein-RNA interaction predictions for model organisms.

More...
RNActi
Q8N0T1, protein

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
ENOG502S982, Eukaryota

Ensembl GeneTree

More...
GeneTreei
ENSGT00390000015564

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
CLU_152931_0_0_1

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q8N0T1

Identification of Orthologs from Complete Genome Data

More...
OMAi
FQVANKQ

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q8N0T1

TreeFam database of animal gene trees

More...
TreeFami
TF330773

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR031389, RBIS

The PANTHER Classification System

More...
PANTHERi
PTHR35544, PTHR35544, 1 hit

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF15679, DUF4665, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequences (2+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry describes 2 <p>This subsection of the 'Sequence' section lists the alternative protein sequences (isoforms) that can be generated from the same gene by a single or by the combination of up to four biological events (alternative promoter usage, alternative splicing, alternative initiation and ribosomal frameshifting). Additionally, this section gives relevant information on each alternative protein isoform. This section is only present in reviewed entries, i.e. in UniProtKB/Swiss-Prot.<p><a href='/help/alternative_products' target='_top'>More...</a></p> isoformsi produced by alternative splicing. AlignAdd to basket

This entry has 2 described isoforms and 2 potential isoforms that are computationally mapped.Show allAlign All

Isoform 1 (identifier: Q8N0T1-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the <div> <p><b>What is the canonical sequence?</b><p><a href='/help/canonical_and_isoforms' target='_top'>More...</a></p>canonicali sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide
        10         20         30         40         50
MAKNKLRGPK SRNVFHIASQ KNFKAKNKAK PVTTNLKKIN IMNEEKVNRV
60 70 80 90 100
NKAFVNVQKE LAHFAKSISL EPLQKELIPQ QRHESKPVNV DEATRLMALL
Length:100
Mass (Da):11,456
Last modified:May 14, 2014 - v4
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i37D727E9E8A27034
GO
Isoform 2 (identifier: Q8N0T1-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     39-100: INIMNEEKVNRVNKAFVNVQKELAHFAKSISLEPLQKELIPQQRHESKPVNVDEATRLMALL → VLHFS

Show »
Length:43
Mass (Da):4,907
Checksum:iD12C37C2541F3E3D
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 2 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
A0A087WWE7A0A087WWE7_HUMAN
Ribosomal biogenesis factor
RBIS
61Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
E5RGR5E5RGR5_HUMAN
Ribosomal biogenesis factor
RBIS
45Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti74Q → L in BC062221 (PubMed:15489334).Curated1

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section describes the sequence of naturally occurring alternative protein isoform(s). The changes in the amino acid sequence may be due to alternative splicing, alternative promoter usage, alternative initiation, or ribosomal frameshifting.<p><a href='/help/var_seq' target='_top'>More...</a></p>Alternative sequenceiVSP_03230439 – 100INIMN…LMALL → VLHFS in isoform 2. 1 PublicationAdd BLAST62

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AC011773 Genomic DNA No translation available.
CH471068 Genomic DNA Translation: EAW87124.1
BC032347 mRNA Translation: AAH32347.1
BC146983 mRNA Translation: AAI46984.1
BC146988 mRNA Translation: AAI46989.1
BC157825 mRNA Translation: AAI57826.1
BC062221 mRNA No translation available.

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS55255.1 [Q8N0T1-1]

NCBI Reference Sequences

More...
RefSeqi
NP_001093140.1, NM_001099670.2 [Q8N0T1-1]
NP_001093141.1, NM_001099671.2 [Q8N0T1-1]
NP_001093142.1, NM_001099672.2 [Q8N0T1-1]
NP_001093143.1, NM_001099673.2 [Q8N0T1-1]
XP_011515830.1, XM_011517528.2 [Q8N0T1-1]

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENST00000321777; ENSP00000319020; ENSG00000176731 [Q8N0T1-2]
ENST00000611854; ENSP00000484811; ENSG00000176731 [Q8N0T1-1]
ENST00000612809; ENSP00000481745; ENSG00000176731 [Q8N0T1-1]
ENST00000612977; ENSP00000484101; ENSG00000176731 [Q8N0T1-1]
ENST00000615697; ENSP00000482944; ENSG00000176731 [Q8N0T1-1]
ENST00000619594; ENSP00000484492; ENSG00000176731 [Q8N0T1-1]

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
401466

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
hsa:401466

UCSC genome browser

More...
UCSCi
uc033bru.2, human [Q8N0T1-1]

Keywords - Coding sequence diversityi

Alternative splicing

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC011773 Genomic DNA No translation available.
CH471068 Genomic DNA Translation: EAW87124.1
BC032347 mRNA Translation: AAH32347.1
BC146983 mRNA Translation: AAI46984.1
BC146988 mRNA Translation: AAI46989.1
BC157825 mRNA Translation: AAI57826.1
BC062221 mRNA No translation available.
CCDSiCCDS55255.1 [Q8N0T1-1]
RefSeqiNP_001093140.1, NM_001099670.2 [Q8N0T1-1]
NP_001093141.1, NM_001099671.2 [Q8N0T1-1]
NP_001093142.1, NM_001099672.2 [Q8N0T1-1]
NP_001093143.1, NM_001099673.2 [Q8N0T1-1]
XP_011515830.1, XM_011517528.2 [Q8N0T1-1]

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

Protein-protein interaction databases

BioGRIDi135095, 6 interactors
IntActiQ8N0T1, 3 interactors
STRINGi9606.ENSP00000484492

PTM databases

iPTMnetiQ8N0T1
PhosphoSitePlusiQ8N0T1

Genetic variation databases

BioMutaiC8orf59
DMDMi519668681

Proteomic databases

EPDiQ8N0T1
jPOSTiQ8N0T1
MassIVEiQ8N0T1
MaxQBiQ8N0T1
PaxDbiQ8N0T1
PeptideAtlasiQ8N0T1
PRIDEiQ8N0T1
ProteomicsDBi15478
71453 [Q8N0T1-1]
71454 [Q8N0T1-2]
TopDownProteomicsiQ8N0T1-1 [Q8N0T1-1]

Protocols and materials databases

Antibodypedia a portal for validated antibodies

More...
Antibodypediai
59064, 34 antibodies

Genome annotation databases

EnsembliENST00000321777; ENSP00000319020; ENSG00000176731 [Q8N0T1-2]
ENST00000611854; ENSP00000484811; ENSG00000176731 [Q8N0T1-1]
ENST00000612809; ENSP00000481745; ENSG00000176731 [Q8N0T1-1]
ENST00000612977; ENSP00000484101; ENSG00000176731 [Q8N0T1-1]
ENST00000615697; ENSP00000482944; ENSG00000176731 [Q8N0T1-1]
ENST00000619594; ENSP00000484492; ENSG00000176731 [Q8N0T1-1]
GeneIDi401466
KEGGihsa:401466
UCSCiuc033bru.2, human [Q8N0T1-1]

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
401466

GeneCards: human genes, protein and diseases

More...
GeneCardsi
RBIS
HGNCiHGNC:32235, RBIS
HPAiENSG00000176731, Low tissue specificity
neXtProtiNX_Q8N0T1
OpenTargetsiENSG00000176731
PharmGKBiPA142672322
VEuPathDBiHostDB:ENSG00000176731.11

GenAtlas: human gene database

More...
GenAtlasi
Search...

Phylogenomic databases

eggNOGiENOG502S982, Eukaryota
GeneTreeiENSGT00390000015564
HOGENOMiCLU_152931_0_0_1
InParanoidiQ8N0T1
OMAiFQVANKQ
PhylomeDBiQ8N0T1
TreeFamiTF330773

Enzyme and pathway databases

PathwayCommonsiQ8N0T1

Miscellaneous databases

BioGRID ORCS database of CRISPR phenotype screens

More...
BioGRID-ORCSi
401466, 41 hits in 578 CRISPR screens

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...
ChiTaRSi
C8orf59, human

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...
GenomeRNAii
401466
PharosiQ8N0T1, Tdark

Protein Ontology

More...
PROi
PR:Q8N0T1
RNActiQ8N0T1, protein

Gene expression databases

BgeeiENSG00000176731, Expressed in metanephros and 215 other tissues
ExpressionAtlasiQ8N0T1, baseline and differential
GenevisibleiQ8N0T1, HS

Family and domain databases

InterProiView protein in InterPro
IPR031389, RBIS
PANTHERiPTHR35544, PTHR35544, 1 hit
PfamiView protein in Pfam
PF15679, DUF4665, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiRBIS_HUMAN
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q8N0T1
Secondary accession number(s): B2RXE7, E5RFW5
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: March 18, 2008
Last sequence update: May 14, 2014
Last modified: April 7, 2021
This is version 121 of the entry and version 4 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. Human chromosome 8
    Human chromosome 8: entries, gene names and cross-references to MIM
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