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Protein

Palmitoyltransferase

Gene

CG4483

Organism
Drosophila melanogaster (Fruit fly)
Status
Unreviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

Catalytic activityi

Palmitoyl-CoA + [protein]-L-cysteine = [protein]-S-palmitoyl-L-cysteine + CoA.UniRule annotation

GO - Molecular functioni

  • protein-cysteine S-palmitoyltransferase activity Source: FlyBase

GO - Biological processi

  • protein palmitoylation Source: FlyBase

Keywordsi

Molecular functionAcyltransferaseUniRule annotation, Transferase

Names & Taxonomyi

Protein namesi
Recommended name:
PalmitoyltransferaseUniRule annotation (EC:2.3.1.225UniRule annotation)
Gene namesi
ORF Names:CG4483Imported
OrganismiDrosophila melanogaster (Fruit fly)Imported
Taxonomic identifieri7227 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraHolometabolaDipteraBrachyceraMuscomorphaEphydroideaDrosophilidaeDrosophilaSophophora

Organism-specific databases

FlyBaseiFBgn0035970 CG4483

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei12 – 32HelicalUniRule annotationAdd BLAST21
Transmembranei137 – 163HelicalUniRule annotationAdd BLAST27
Transmembranei183 – 208HelicalUniRule annotationAdd BLAST26

Keywords - Cellular componenti

Membrane

PTM / Processingi

Proteomic databases

PRIDEiQ8MSL3

Expressioni

Gene expression databases

BgeeiFBgn0035970
ExpressionAtlasiQ8MSL3 differential

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini90 – 225DHHCInterPro annotationAdd BLAST136

Domaini

The DHHC domain is required for palmitoyltransferase activity.UniRule annotation

Sequence similaritiesi

Belongs to the DHHC palmitoyltransferase family.UniRule annotation

Keywords - Domaini

Transmembrane, Transmembrane helixUniRule annotation

Phylogenomic databases

eggNOGiKOG1314 Eukaryota
COG5273 LUCA
OrthoDBiEOG091G0HOK

Family and domain databases

InterProiView protein in InterPro
IPR001594 Palmitoyltrfase_DHHC
PfamiView protein in Pfam
PF01529 DHHC, 1 hit

Sequencei

Sequence statusi: Complete.

Q8MSL3-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MCIKLKDDLR RFMHWGPITL LTLTLIVTWT VIHMNSMWWA PGSSLESVLN
60 70 80 90 100
YALIWIQTFG TLYNFIRSLM VGPGFVPLKW HPQLAKDKMF LQFCTRCNGY
110 120 130 140 150
KAPRSHHCRR CDRCVMKMDH HCPWINTCVG WSNQDSFVYF LLFFMSGSIH
160 170 180 190 200
GGIIIVSAVI QGIKKRWLIR LGLRHMATVH LTQTNLLACV FSLGVIMGTV
210 220 230 240 250
LASIKLLYMQ MKSILKNQTE IENWIVKKAA FRRNAYPRKG IKPFVYPYNL
260 270 280 290 300
GWKTNIREVF LSTGDGISWP VLPECNEYSL TCEQLQQKKD KRARTRVFRC
310 320 330 340 350
IRPATGHWVP IFSQGLWVSL QIPCTDDPRI ALKPDDIIHV TRIQEYWLYG
360 370 380 390 400
EIMISEKQKE KIRARNGAIR GWFPSCCAIE ICEDSDSEND LAGGEPVKEQ
410 420 430
DTAAIESVET DQEIIDFMRD FSCNDGKKAK RLHIE
Length:435
Mass (Da):50,316
Last modified:October 1, 2002 - v1
Checksum:i5C5F14986016F232
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AY118715 mRNA Translation: AAM50575.1

Similar proteinsi

Entry informationi

Entry nameiQ8MSL3_DROME
AccessioniPrimary (citable) accession number: Q8MSL3
Entry historyiIntegrated into UniProtKB/TrEMBL: October 1, 2002
Last sequence update: October 1, 2002
Last modified: January 31, 2018
This is version 74 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

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