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UniProtKB - Q8MRJ2 (Q8MRJ2_DROME)
Protein
Submitted name:
LD11139p
Gene
Dmel\CG11069
Organism
Drosophila melanogaster (Fruit fly)
Status
Functioni
Caution
Lacks conserved residue(s) required for the propagation of feature annotation.PROSITE-ProRule annotation
GO - Molecular functioni
- ATP binding Source: UniProtKB-UniRule
- hydrolase activity Source: UniProtKB-KW
Keywordsi
Molecular function | HydrolaseImported |
Ligand | ATP-bindingPROSITE-ProRule annotation, Nucleotide-binding |
Names & Taxonomyi
Protein namesi | Submitted name: LD11139pImported |
Gene namesi | Name:Dmel\CG11069Imported ORF Names:CG11069Imported, Dmel_CG11069Imported |
Organismi | Drosophila melanogaster (Fruit fly)Imported |
Taxonomic identifieri | 7227 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Ecdysozoa › Arthropoda › Hexapoda › Insecta › Pterygota › Neoptera › Endopterygota › Diptera › Brachycera › Muscomorpha › Ephydroidea › Drosophilidae › Drosophila › Sophophora › |
Proteomesi |
|
Organism-specific databases
FlyBasei | FBgn0039244, CG11069 |
VEuPathDBi | VectorBase:FBgn0039244 |
Subcellular locationi
Other locations
- integral component of membrane Source: UniProtKB-KW
Topology
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Transmembranei | 318 – 336 | HelicalSequence analysisAdd BLAST | 19 | |
Transmembranei | 341 – 359 | HelicalSequence analysisAdd BLAST | 19 | |
Transmembranei | 379 – 398 | HelicalSequence analysisAdd BLAST | 20 | |
Transmembranei | 418 – 442 | HelicalSequence analysisAdd BLAST | 25 | |
Transmembranei | 454 – 478 | HelicalSequence analysisAdd BLAST | 25 | |
Transmembranei | 485 – 504 | HelicalSequence analysisAdd BLAST | 20 | |
Transmembranei | 572 – 593 | HelicalSequence analysisAdd BLAST | 22 |
Keywords - Cellular componenti
MembraneExpressioni
Gene expression databases
Bgeei | FBgn0039244, Expressed in capitellum (Drosophila) and 47 other tissues |
Structurei
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 10 – 251 | ABC transporterInterPro annotationAdd BLAST | 242 |
Keywords - Domaini
Transmembrane, Transmembrane helixSequence analysisPhylogenomic databases
eggNOGi | KOG0061, Eukaryota |
GeneTreei | ENSGT00940000157985 |
HOGENOMi | CLU_000604_57_9_1 |
OMAi | QPWLQDN |
OrthoDBi | 1022017at2759 |
Family and domain databases
Gene3Di | 3.40.50.300, 1 hit |
InterProi | View protein in InterPro IPR003439, ABC_transporter-like_ATP-bd IPR027417, P-loop_NTPase |
Pfami | View protein in Pfam PF00005, ABC_tran, 1 hit |
SUPFAMi | SSF52540, SSF52540, 1 hit |
PROSITEi | View protein in PROSITE PS50893, ABC_TRANSPORTER_2, 1 hit |
i Sequence
Sequence statusi: Complete.
Q8MRJ2-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MKMIGSDYVL EAHNIFHTTE VDGGGCFNGA GNSALVLKGV NLTVHSGEVM
60 70 80 90 100
AILGSKGSGK RALLDVISRR ADGATRGQVL LNGSPLSKAL FQQRCGYVTQ
110 120 130 140 150
SCTFVPGLTV AQTLHYTPTI LSGYLKSSKV RQVLADLALS QVAHKRVEYL
160 170 180 190 200
NISEARRLAI GIQLVRDPVM LLLDEPTHGL DPLSAYLLIS ILSNTAKKTG
210 220 230 240 250
CGILLSLEKP RSDVFPFLDR ALFLCLGGVV YSGGTRAMLE YFHGIGFPCP
260 270 280 290 300
QLENPLMYYL CLSTVDRRSR DRFLESSQQI EALVERFSRE TPISDAPLNN
310 320 330 340 350
MGSGKVPLAY GKPGELKVWV MLYLKLLAST FSCGLVGMKT LFLRLLLLPL
360 370 380 390 400
ALSILWAFYT DVGDDSHGFF TKNGMILNIL GLSYGCGILT TISLFPIWRK
410 420 430 440 450
KFSQDTPEGL YSGTTLLIAY NSVSIPFSAV SAVIASCVVY PLLLDVKYNN
460 470 480 490 500
GTVFAYLLVA LWSSFVLAEQ LTIAFLLVVK VPFNAAIAVT YVLVISIALA
510 520 530 540 550
SGTVRSFKGL QPWLQDNTKG THTRYASSLL HSIAFQSRKL NCTPTASVIC
560 570 580 590 600
PKPADFMHER LGLPDPDETI DVAASCAFAV GLAAFNMLVY LFPMPRCVRQ
KFKD
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AE014297 Genomic DNA Translation: AAF56361.2 AY119582 mRNA Translation: AAM50236.1 |
RefSeqi | NP_651307.2, NM_143050.2 |
Genome annotation databases
EnsemblMetazoai | FBtr0084712; FBpp0084089; FBgn0039244 |
GeneIDi | 42976 |
KEGGi | dme:Dmel_CG11069 |
UCSCi | CG11069-RA, d. melanogaster |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AE014297 Genomic DNA Translation: AAF56361.2 AY119582 mRNA Translation: AAM50236.1 |
RefSeqi | NP_651307.2, NM_143050.2 |
3D structure databases
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Protein-protein interaction databases
STRINGi | 7227.FBpp0084089 |
Protocols and materials databases
DNASUi | 42976 |
Genome annotation databases
EnsemblMetazoai | FBtr0084712; FBpp0084089; FBgn0039244 |
GeneIDi | 42976 |
KEGGi | dme:Dmel_CG11069 |
UCSCi | CG11069-RA, d. melanogaster |
Organism-specific databases
FlyBasei | FBgn0039244, CG11069 |
VEuPathDBi | VectorBase:FBgn0039244 |
Phylogenomic databases
eggNOGi | KOG0061, Eukaryota |
GeneTreei | ENSGT00940000157985 |
HOGENOMi | CLU_000604_57_9_1 |
OMAi | QPWLQDN |
OrthoDBi | 1022017at2759 |
Miscellaneous databases
BioGRID-ORCSi | 42976, 0 hits in 1 CRISPR screen |
ChiTaRSi | CG11069, fly |
GenomeRNAii | 42976 |
Gene expression databases
Bgeei | FBgn0039244, Expressed in capitellum (Drosophila) and 47 other tissues |
Family and domain databases
Gene3Di | 3.40.50.300, 1 hit |
InterProi | View protein in InterPro IPR003439, ABC_transporter-like_ATP-bd IPR027417, P-loop_NTPase |
Pfami | View protein in Pfam PF00005, ABC_tran, 1 hit |
SUPFAMi | SSF52540, SSF52540, 1 hit |
PROSITEi | View protein in PROSITE PS50893, ABC_TRANSPORTER_2, 1 hit |
MobiDBi | Search... |
Entry informationi
Entry namei | Q8MRJ2_DROME | |
Accessioni | Q8MRJ2Primary (citable) accession number: Q8MRJ2 Secondary accession number(s): Q9VC15 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | October 1, 2002 |
Last sequence update: | October 1, 2002 | |
Last modified: | January 19, 2022 | |
This is version 174 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) |