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Protein
Submitted name:

SD06708p

Gene

mbc

Organism
Drosophila melanogaster (Fruit fly)
Status
Unreviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

  • Rac guanyl-nucleotide exchange factor activity Source: FlyBase

GO - Biological processi

  • actin cytoskeleton organization Source: FlyBase
  • activation of GTPase activity Source: FlyBase
  • anterior Malpighian tubule development Source: FlyBase
  • border follicle cell migration Source: FlyBase
  • cell competition in a multicellular organism Source: FlyBase
  • cell morphogenesis Source: FlyBase
  • central nervous system development Source: FlyBase
  • cytoskeleton organization Source: FlyBase
  • dorsal closure Source: FlyBase
  • larval visceral muscle development Source: FlyBase
  • muscle attachment Source: FlyBase
  • myoblast fusion Source: FlyBase
  • small GTPase mediated signal transduction Source: InterPro

Names & Taxonomyi

Protein namesi
Submitted name:
SD06708pImported
Gene namesi
Name:mbcImported
ORF Names:CG10379Imported
OrganismiDrosophila melanogaster (Fruit fly)Imported
Taxonomic identifieri7227 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraHolometabolaDipteraBrachyceraMuscomorphaEphydroideaDrosophilidaeDrosophilaSophophora

Organism-specific databases

FlyBaseiFBgn0015513 mbc

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

PTM / Processingi

Proteomic databases

PRIDEiQ8MQW7

Expressioni

Gene expression databases

BgeeiFBgn0015513
ExpressionAtlasiQ8MQW7 baseline and differential

Interactioni

GO - Molecular functioni

  • Rac guanyl-nucleotide exchange factor activity Source: FlyBase

Protein-protein interaction databases

IntActiQ8MQW7, 3 interactors

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini573 – 986DHR-2InterPro annotationAdd BLAST414

Sequence similaritiesi

Belongs to the DOCK family.PROSITE-ProRule annotation

Phylogenomic databases

eggNOGiKOG1998 Eukaryota
ENOG410XQH7 LUCA
OrthoDBiEOG091G007D

Family and domain databases

InterProiView protein in InterPro
IPR027357 DHR-2
IPR026791 DOCK
IPR031057 DOCK1_homologue
IPR010703 DOCK_C
PANTHERiPTHR23317 PTHR23317, 1 hit
PTHR23317:SF69 PTHR23317:SF69, 1 hit
PfamiView protein in Pfam
PF06920 DHR-2, 1 hit
PROSITEiView protein in PROSITE
PS51651 DHR_2, 1 hit

Sequencei

Sequence statusi: Fragment.

Q8MQW7-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
NDHPEKYDQL VFMSIIHLIE TVSDLKYQHF LSVLDVYINE SFSFTLAYTK
60 70 80 90 100
LMDVLQKNIS EAISPKEKSA DGNDLEESPE VRRLYKTTRY LHYVMKFVIR
110 120 130 140 150
SRVLYAEMNC NTDYMDFATR LQELLRMFID MIGCPSNLLK SEGALLKNLH
160 170 180 190 200
IIATDLMQVF EHVRLSISIV EILEKFPPRR LTQSKMGCIK DFVETKLFTL
210 220 230 240 250
PKCRAILLPV FCKHIKDHLE SKEEIAECIN IMNNILKLLF RSDVGSTHND
260 270 280 290 300
IRDIMIILFR TVMKAAHALD RDTGLVGKFF AIMLGILQRM DAQHYEYFVK
310 320 330 340 350
DLHQSGELKH FVIEILLVFE ELVSPHQKAV FPRDWMDMIM HQNTVILGAL
360 370 380 390 400
KHLTVVITDY FLCPFEKQIW SNFFQCSIAF LVQSPLQLND FNDNKRQIVF
410 420 430 440 450
ARYRDIRKDT AMEIRKMWFQ LGQHKPKFVP QLVEPILEMS MIPEKELRQE
460 470 480 490 500
TIPIFFDMMQ CEYYSSRLEH ESYGDTKFNN AHHKGNFSDF KTAMIEKLDI
510 520 530 540 550
LIGAGKGDAE YKHLFETIML ERCAAHNTLN VDGTAFVQMV TRLMDKLLEY
560 570 580 590 600
RFIIQDESKE NRMACTFSLL QFYSEVDLKE MYIRYVNKLC ALHMEFENYT
610 620 630 640 650
EAAFTLKLHT ELLRWTDTEL SHQLRSYRHN NCRTHRQLKE ALYFEIMEYF
660 670 680 690 700
DKGKQWECAI DMCRVLARQY EEEIFDYLKL AELLNRMALF YEKIIKELRH
710 720 730 740 750
NSEYFRVCFY GRGFPRFLQN RVYIFRGKEY ERHSDFCARM LVQHPQAELM
760 770 780 790 800
QTLEAPGDDI TNSDGQYIQV NKVEPIMGQA FNKFNDKIIN NEIVKYFTAN
810 820 830 840 850
NVQKFQFSRP FRDSTNGGDR DDVRNLWLER TELRISYPLP GILRWFPVVE
860 870 880 890 900
TNTFKISPLE RAVEIMKDTN RDIRQLVILH KSDETLHINP LSMKLNGIVD
910 920 930 940 950
PAVMGGFAKY EEAFLTDDYL EQNPDDKELV EELKELIANQ IPLLDLAIQL
960 970 980 990 1000
HRLRAPDSLK ALQEHLERCF ADMQQHVEQR YGRKSCDLKI ERDSVVMRRP
1010 1020 1030 1040 1050
NSFLPSLFDG SNNRHSETSM GSSDSGLSKS TFLPRPQTNS IKNPFSGLSF
1060 1070 1080 1090 1100
NTRPSLGHSP SIKSNKSKDK TPSKRRTKDG KVKEREAHSL SSSQWYTPPL
1110 1120 1130 1140 1150
STITSTPEKE INTSIASLAS TSNSSLSGPK TPDPHVLTEE LTPKRPLRSE
1160 1170 1180 1190 1200
MEKERRLSRP ASIATPTASI KNFPDTRSLS ESSNRNSVET TDSTSEEDIR
1210 1220 1230 1240 1250
PPPLPAKARD STDFTSLSQN MDWTPNGYAM LSTISNTSSM STTSTLTKTS
1260 1270 1280 1290
ITNTTYEYLE TTNFSLVGAI DGNKPRPPTP PPKPSRHSKH IP
Length:1,292
Mass (Da):150,006
Last modified:October 1, 2002 - v1
Checksum:iAF31DA9B325EDB80
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei1Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AY122254 mRNA Translation: AAM52766.1

Genome annotation databases

EnsemblMetazoaiFBtr0084459; FBpp0083850; FBgn0015513

Similar proteinsi

Entry informationi

Entry nameiQ8MQW7_DROME
AccessioniPrimary (citable) accession number: Q8MQW7
Entry historyiIntegrated into UniProtKB/TrEMBL: October 1, 2002
Last sequence update: October 1, 2002
Last modified: July 18, 2018
This is version 92 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

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