Transketolase

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functionⁱ

<p>This subsection of the <a href="http://www.uniprot.org/help/function_section">Function</a> section describes the catalytic activity of an enzyme, i.e. the chemical reaction it catalyzes. This information usually correlates with the presence of an EC (Enzyme Commission) number in the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section.<p><a href='/help/catalytic_activity' target='_top'>More...</a></p>Catalytic activityⁱ

<p>This subsection of the ‘Function’ section provides information relevant to cofactors. A cofactor is any non-protein substance required for a protein to be catalytically active. Some cofactors are inorganic, such as the metal atoms zinc, iron, and copper in various oxidation states. Others, such as most vitamins, are organic.<p><a href='/help/cofactor' target='_top'>More...</a></p>Cofactorⁱ

• Mg²⁺UniRule annotation

  Automatic assertion according to rulesⁱ

  • RuleBase:RU004996
  , Ca²⁺UniRule annotation

  Automatic assertion according to rulesⁱ

  • RuleBase:RU004996
  , Mn²⁺UniRule annotation

  Automatic assertion according to rulesⁱ

  • RuleBase:RU004996
  , Co²⁺UniRule annotation

  Automatic assertion according to rulesⁱ

  • RuleBase:RU004996
  Note: Binds 1 Mg²⁺ ion per subunit. Can also utilize other divalent metal cations, such as Ca²⁺, Mn²⁺ and Co²⁺.UniRule annotation

  Automatic assertion according to rulesⁱ

  • RuleBase:RU004996
• thiamine diphosphateUniRule annotation

  Automatic assertion according to rulesⁱ

  • RuleBase:RU004996
  Note: Binds 1 thiamine pyrophosphate per subunit.UniRule annotation

  Automatic assertion according to rulesⁱ

  • RuleBase:RU004996

Sites

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functionⁱ

• metal ion binding Source: UniProtKB-KW
• transketolase activity Source: UniProtKB-EC

GO - Biological processⁱ

• metabolic process Source: InterPro

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsⁱ

Enzyme and pathway databases

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyⁱ

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactionⁱ

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction_section">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function_section">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structureⁱ

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structureⁱ

3D structure databases

Miscellaneous databases

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsⁱ

Domains and Repeats

Region

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesⁱ

Family and domain databases

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>.<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequenceⁱ

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusⁱ: Complete.

        10         20         30         40         50
MASIEKVANC IRCLAADIVQ GGKSGHPGTP MGMAPMSAVL WTEVMKYNSQ 
        60         70         80         90        100
DPDWVDRDRF VMSNGHGCAL QYALLHMAGY NLTMDDLKGF RQDGSRTPGH 
       110        120        130        140        150
PERFVTPGVE VTTGPLGQGI ANAVGLAIAE AHLAATFNRP GYNIVDHYTY 
       160        170        180        190        200
VYCGDGCLME GVCQEALSLA GHLALEKLIV IYDSNYISID GSTSLSFTEQ 
       210        220        230        240        250
CHQKYVAMGF HVIEVKNGDT DYEGLRKALA EAKATKGKPK MIVQTTTIGF 
       260        270        280        290        300
GSSKQGTEKV HGAPLGEEDI ANIKAKFGRD PQKKYDVDDD VRAVFRMHID 
       310        320        330        340        350
KCSAEQKAWE ELLAKYTAAF PAEGAAFVAQ MRGELPSGWE AKLPTNSSAI 
       360        370        380        390        400
ATRKASENCL AVLFPAIPAL MGGSADLTPS NLTRPASANL VDFSSSSKEG 
       410        420        430        440        450
RYIRFGVREH AMCAILNGLD AHDGIIPFGG TFLNFIGYAL GAVRLAAISH 
       460        470        480        490        500
HRVIYVATHD SIGVGEDGPT HQPVELVAAL RAMPNLQVIR PSDQTETSGA 
       510        520        530        540        550
WAVALSSIHT PTVLCLSRQN TEPQSGSSIE GVRHGAYSVV DVPDLQLVIV 
       560        570        580        590        600
ASGSEVSLAV DAAKALSGEL RVRVVSMPCQ ELFDAQPDTY RQAVLPAGVP 
       610        620        630        640        650
VVSVEAYVSF GWEKYSHAHV GMSGFGASAP AGVLYKKFGI TVEEVVRTGR 
       660        670 
ELAKRFPDGT APLKNSSFSK M                                

Sequence databases

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsⁱ

• 90% Identity
• 50% Identity

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationⁱ

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousⁱ

Keywords - Technical termⁱ