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Protein

General odorant-binding protein 57d

Gene

Obp57d

Organism
Drosophila melanogaster (Fruit fly)
Status
Reviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

Present in the aqueous fluid surrounding olfactory sensory dendrites and are thought to aid in the capture and transport of hydrophobic odorants into and through this fluid.Curated

GO - Molecular functioni

GO - Biological processi

  • response to odorant Source: UniProtKB
  • sensory perception of chemical stimulus Source: FlyBase
  • sensory perception of smell Source: GO_Central

Keywordsi

Biological processOlfaction, Sensory transduction, Transport

Names & Taxonomyi

Protein namesi
Recommended name:
General odorant-binding protein 57d
Gene namesi
Name:Obp57dImported
ORF Names:CG30150
OrganismiDrosophila melanogaster (Fruit fly)
Taxonomic identifieri7227 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraHolometabolaDipteraBrachyceraMuscomorphaEphydroideaDrosophilidaeDrosophilaSophophora
Proteomesi
  • UP000000803 Componenti: Chromosome 2R

Organism-specific databases

FlyBaseiFBgn0043536 Obp57d

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 29Sequence analysisAdd BLAST29
ChainiPRO_000001257530 – 136General odorant-binding protein 57dSequence analysisAdd BLAST107

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Disulfide bondi33 ↔ 70By similarity
Disulfide bondi66 ↔ 118By similarity
Disulfide bondi107 ↔ 127By similarity

Keywords - PTMi

Disulfide bond

Proteomic databases

PaxDbiQ8MMF9
PRIDEiQ8MMF9

Expressioni

Gene expression databases

BgeeiFBgn0043536
GenevisibleiQ8MMF9 DM

Structurei

3D structure databases

ProteinModelPortaliQ8MMF9
SMRiQ8MMF9
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the PBP/GOBP family.Sequence analysis

Keywords - Domaini

Signal

Phylogenomic databases

InParanoidiQ8MMF9
OrthoDBiEOG091G0SCJ

Family and domain databases

Gene3Di1.10.238.20, 1 hit
InterProiView protein in InterPro
IPR006170 PBP_GOBP
IPR036728 PBP_GOBP_sf
PfamiView protein in Pfam
PF01395 PBP_GOBP, 1 hit
SUPFAMiSSF47565 SSF47565, 1 hit

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

Q8MMF9-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MPEKMSLRLV PHLACIIFIL EIQFRIADSN DPCPHNQGID EDIAESILGD
60 70 80 90 100
WPANVDLTSV KRSHKCYVTC ILQYYNIVTT SGEIFLDKYY DTGVIDELAV
110 120 130
APKINRCRYE FRMETDYCSR IFAIFNCLRQ EILTKS
Length:136
Mass (Da):15,747
Last modified:March 1, 2005 - v2
Checksum:i3073A70754EE7A4F
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence conflicti80T → A in AAM68388 (PubMed:10731132).Curated1

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Natural varianti10V → I in strain: Canton-S, KY02013G20 and KY02073G20. 1
Natural varianti28D → E in strain: KY02106G9 and MEL6G59. 1
Natural varianti58T → I in strain: Canton-S, KY02010G20, KY02013G20 and KY02073G20. 1
Natural varianti87D → E in strain: KY02106G9. 1 Publication1
Natural varianti87D → N in strain: Canton-S, KY02010G20, KY02073G20 and KY02013G20. 1
Natural varianti99A → T in strain: KY02106G9. 1 Publication1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF457149 mRNA Translation: AAM69287.1
AB189644 Genomic DNA Translation: BAD83885.1
AB189645 Genomic DNA Translation: BAD83887.1
AB189646 Genomic DNA Translation: BAD83889.1
AB189647 Genomic DNA Translation: BAD83891.1
AB189648 Genomic DNA Translation: BAD83893.1
AB189649 Genomic DNA Translation: BAD83894.1
AB189650 Genomic DNA Translation: BAD83895.1
AB189651 Genomic DNA Translation: BAD83896.1
AB189652 Genomic DNA Translation: BAD83897.1
AB189653 Genomic DNA Translation: BAD83898.1
AB189654 Genomic DNA Translation: BAD83899.1
AB189655 Genomic DNA Translation: BAD83900.1
AB189656 Genomic DNA Translation: BAD83901.1
AB189657 Genomic DNA Translation: BAD83902.1
AB189658 Genomic DNA Translation: BAD83903.1
AB189659 Genomic DNA Translation: BAD83904.1
AB189660 Genomic DNA Translation: BAD83905.1
AB189661 Genomic DNA Translation: BAD83907.1
AB189663 Genomic DNA Translation: BAD83910.1
AB189664 Genomic DNA Translation: BAD83911.1
AB189665 Genomic DNA Translation: BAD83912.1
AB189666 Genomic DNA Translation: BAD83913.1
AB189667 Genomic DNA Translation: BAD83915.1
AE013599 Genomic DNA Translation: AAM68388.1
RefSeqiNP_725973.1, NM_166397.3

Genome annotation databases

GeneIDi246671
KEGGidme:Dmel_CG30150

Similar proteinsi

Entry informationi

Entry nameiOB57D_DROME
AccessioniPrimary (citable) accession number: Q8MMF9
Secondary accession number(s): Q5KS14
, Q5KS20, Q5KS26, Q5KS32, Q5KS34, Q8MVX5
Entry historyiIntegrated into UniProtKB/Swiss-Prot: March 1, 2005
Last sequence update: March 1, 2005
Last modified: April 25, 2018
This is version 88 of the entry and version 2 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programDrosophila annotation project

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Drosophila
    Drosophila: entries, gene names and cross-references to FlyBase
  2. SIMILARITY comments
    Index of protein domains and families

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