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Protein

Palmitoyltransferase

Gene

CG10344

Organism
Drosophila melanogaster (Fruit fly)
Status
Unreviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

Catalytic activityi

Palmitoyl-CoA + [protein]-L-cysteine = [protein]-S-palmitoyl-L-cysteine + CoA.UniRule annotation

GO - Molecular functioni

  • protein-cysteine S-palmitoyltransferase activity Source: FlyBase

GO - Biological processi

  • protein palmitoylation Source: FlyBase

Keywordsi

Molecular functionAcyltransferaseUniRule annotationImported, Transferase

Names & Taxonomyi

Protein namesi
Recommended name:
PalmitoyltransferaseUniRule annotation (EC:2.3.1.225UniRule annotation)
Gene namesi
ORF Names:CG10344Imported, Dmel_CG10344Imported
OrganismiDrosophila melanogaster (Fruit fly)Imported
Taxonomic identifieri7227 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraHolometabolaDipteraBrachyceraMuscomorphaEphydroideaDrosophilidaeDrosophilaSophophora
Proteomesi
  • UP000000803 Componenti: Chromosome 2R

Organism-specific databases

FlyBaseiFBgn0034729 CG10344

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei12 – 40HelicalUniRule annotationAdd BLAST29
Transmembranei46 – 62HelicalUniRule annotationAdd BLAST17
Transmembranei139 – 160HelicalUniRule annotationAdd BLAST22

Keywords - Cellular componenti

Membrane

PTM / Processingi

Proteomic databases

PRIDEiQ8MKK7

Expressioni

Gene expression databases

BgeeiFBgn0034729

Interactioni

Protein-protein interaction databases

IntActiQ8MKK7, 3 interactors

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini91 – 187DHHCInterPro annotationAdd BLAST97

Domaini

The DHHC domain is required for palmitoyltransferase activity.UniRule annotation

Sequence similaritiesi

Belongs to the DHHC palmitoyltransferase family.UniRule annotation

Keywords - Domaini

Transmembrane, Transmembrane helixUniRule annotation

Phylogenomic databases

GeneTreeiENSGT00850000132405
OrthoDBiEOG091G0RWR

Family and domain databases

InterProiView protein in InterPro
IPR001594 Palmitoyltrfase_DHHC
PfamiView protein in Pfam
PF01529 DHHC, 1 hit

Sequencei

Sequence statusi: Complete.

Q8MKK7-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MRIRSNPMPS RMVDILCFLI IAVFLPVVFM FEIVVVLPAF HEPGGFFHTF
60 70 80 90 100
TFLMAMFLVF NIKGNMIACM MIDTSVNVKK VEPPSDQLNW RECGECQKLA
110 120 130 140 150
PPRSWHCKAC KVCILKRDHH CIYTGCCIGL RNHRFFMGFI FYLFVGSVYA
160 170 180 190
LVYNSIYMWV IHGHIYSNWV TVLKLACPML HLLWLMESSS WPTMCPLF
Length:198
Mass (Da):23,048
Last modified:October 1, 2002 - v1
Checksum:i59D96F58CD4CFF16
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AY118286 mRNA Translation: AAM48315.1
AE013599 Genomic DNA Translation: AAM68226.1
RefSeqiNP_726201.1, NM_166534.3
UniGeneiDm.20177

Genome annotation databases

EnsemblMetazoaiFBtr0071840; FBpp0071751; FBgn0034729
GeneIDi37565
UCSCiCG10344-RA d. melanogaster

Similar proteinsi

Entry informationi

Entry nameiQ8MKK7_DROME
AccessioniPrimary (citable) accession number: Q8MKK7
Entry historyiIntegrated into UniProtKB/TrEMBL: October 1, 2002
Last sequence update: October 1, 2002
Last modified: July 18, 2018
This is version 150 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

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