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Protein

Putative L-type amino acid transporter 1-like protein MLAS

Gene

SLC7A5P1

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score: -Protein uncertaini

Functioni

Caution

Could be the product of a pseudogene.Curated

GO - Molecular functioni

GO - Biological processi

Names & Taxonomyi

Protein namesi
Recommended name:
Putative L-type amino acid transporter 1-like protein MLAS
Alternative name(s):
hLAT1 3-transmembrane protein MLAS
Short name:
hLAT1 3TM MLAS
Gene namesi
Name:SLC7A5P1
Synonyms:MLAS
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Unplaced

Organism-specific databases

HGNCiHGNC:29458 SLC7A5P1
neXtProtiNX_Q8MH63

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei56 – 76HelicalSequence analysisAdd BLAST21
Transmembranei84 – 104HelicalSequence analysisAdd BLAST21
Transmembranei133 – 157HelicalSequence analysisAdd BLAST25

Keywords - Cellular componenti

Membrane

Pathology & Biotechi

Polymorphism and mutation databases

DMDMi74750867

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00003482511 – 180Putative L-type amino acid transporter 1-like protein MLASAdd BLAST180

Proteomic databases

MaxQBiQ8MH63
PeptideAtlasiQ8MH63
PRIDEiQ8MH63
ProteomicsDBi71446

Expressioni

Tissue specificityi

Expressed in peripheral blood mononuclear cells and lymphoid and myeloid cell lines.1 Publication

Organism-specific databases

HPAiHPA052673

Structurei

3D structure databases

ProteinModelPortaliQ8MH63
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

HOVERGENiHBG061804
InParanoidiQ8MH63

Family and domain databases

InterProiView protein in InterPro
IPR002293 AA/rel_permease1
PfamiView protein in Pfam
PF13520 AA_permease_2, 1 hit

Sequencei

Sequence statusi: Complete.

Q8MH63-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAGAGPKRRA LAAPVAEEKE EAREKMLASK RADGAAPAGE GEGVTLQRNI
60 70 80 90 100
TLLNGVAIIV GAIIGSGIFV TPTGVLKEAG SPGLALVMWA ACGVFSIVGA
110 120 130 140 150
LCYAELGTTI SKSGGDYAYM LDVYGSLPAF LKLWIELLVI RPSSQYIVAL
160 170 180
VFATYLLKPL FPSCPVPEEA AKLMACHCVH
Length:180
Mass (Da):18,779
Last modified:October 1, 2002 - v1
Checksum:i60A302239800C3F8
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB055226 mRNA Translation: BAB97212.1
UniGeneiHs.677169

Similar proteinsi

Entry informationi

Entry nameiLAT1N_HUMAN
AccessioniPrimary (citable) accession number: Q8MH63
Entry historyiIntegrated into UniProtKB/Swiss-Prot: September 2, 2008
Last sequence update: October 1, 2002
Last modified: June 20, 2018
This is version 89 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Human chromosome 16
    Human chromosome 16: entries, gene names and cross-references to MIM
  2. SIMILARITY comments
    Index of protein domains and families

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