Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Entry version 93 (12 Aug 2020)
Sequence version 1 (01 Oct 2002)
Previous versions | rss
Add a publicationFeedback
Protein

Protein IQ-DOMAIN 14

Gene

IQD14

Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed-Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

May be involved in cooperative interactions with calmodulins or calmodulin-like proteins. May associate with nucleic acids and regulate gene expression at the transcriptional or post-transcriptional level (By similarity).By similarity

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Protein IQ-DOMAIN 14
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:IQD14
Ordered Locus Names:At2g43680
ORF Names:F18O19.21
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiArabidopsis thaliana (Mouse-ear cress)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri3702 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliopsidaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000006548 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 2

Organism-specific databases

Arabidopsis Information Portal

More...
Araporti
AT2G43680

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00003111211 – 668Protein IQ-DOMAIN 14Add BLAST668

Proteomic databases

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q8LPG9

PRoteomics IDEntifications database

More...
PRIDEi
Q8LPG9

ProteomicsDB: a multi-organism proteome resource

More...
ProteomicsDBi
228832 [Q8LPG9-1]

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
Q8LPG9

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
Q8LPG9, baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
Q8LPG9, AT

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGRID)

More...
BioGRIDi
4306, 2 interactors

STRING: functional protein association networks

More...
STRINGi
3702.AT2G43680.1

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini321 – 350IQ 1PROSITE-ProRule annotationAdd BLAST30
Domaini343 – 372IQ 2PROSITE-ProRule annotationAdd BLAST30

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi33 – 38Poly-Lys6
Compositional biasi78 – 319Pro-richAdd BLAST242

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the IQD family.Curated

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Domaini

Repeat

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
ENOG502R9C0, Eukaryota

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
CLU_025762_0_0_1

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q8LPG9

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q8LPG9

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR025064, DUF4005
IPR000048, IQ_motif_EF-hand-BS

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF13178, DUF4005, 1 hit
PF00612, IQ, 1 hit

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00015, IQ, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS50096, IQ, 2 hits

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry describes 1 <p>This subsection of the 'Sequence' section lists the alternative protein sequences (isoforms) that can be generated from the same gene by a single or by the combination of up to four biological events (alternative promoter usage, alternative splicing, alternative initiation and ribosomal frameshifting). Additionally, this section gives relevant information on each alternative protein isoform. This section is only present in reviewed entries, i.e. in UniProtKB/Swiss-Prot.<p><a href='/help/alternative_products' target='_top'>More...</a></p> isoform i produced by alternative splicing. AlignAdd to basket
Note: A number of isoforms are produced. According to EST sequences.

This entry has 1 described isoform and 1 potential isoform that is computationally mapped.Show allAlign All

Isoform 1 (identifier: Q8LPG9-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the <div> <p><b>What is the canonical sequence?</b><p><a href='/help/canonical_and_isoforms' target='_top'>More...</a></p>canonicali sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide
        10         20         30         40         50
MVKKGSWFSA IKRVFTPHSK EKLANEPERK SGKEKKKKGF GKLRHGETNS
60 70 80 90 100
FLPIFREPSS IEKILGEAER DHNLVFRPPT PDRPNPYSAS PPPRPASPRV
110 120 130 140 150
ASPRPTSPRV ASPRVPSPRA EVPRTLSPKP PSPRAEVPRS LSPKPPSPRA
160 170 180 190 200
DLPRSLSPKP FDRSKPSSAS ANAPPTLRPA STRVPSQRIT PHSVPSPRPS
210 220 230 240 250
SPRGASPQAI SSKPPSPRAE PPTLDTPRPP SPRAASLRAD PPRLDAARPT
260 270 280 290 300
TPRPPSPLAD APRLDAPRPT TPKPPSPRSD PPRLDAPRPT TPKPPSPRSV
310 320 330 340 350
SPRAVQRREI VYRPEPTLPV QHASATKIQG AFRGYMARKS FRALKGLVRL
360 370 380 390 400
QGVVRGYSVK RQTINAMKYM QQVVRVQSQI QSRRIKMLEN QAQVEKDEAK
410 420 430 440 450
WAASEAGNDN WDDSVLTKEE RDSRSQRKTD AIIKRERSMA YAYSRKLWKN
460 470 480 490 500
SPKSTQDNRS FPQWWNWVDR QNPLASPAPS YSQPQRDFRL TPSRLCPSPL
510 520 530 540 550
SQSSKQHHIR LDNHFDTSTP RSSRSTFHTP SRPIHTGTSR YSRGRLRGQD
560 570 580 590 600
SPFKDDDSLT SCPPFPSYMA PTVSAKAKVR PNSNPKERVM GTPVSEKRRM
610 620 630 640 650
SYPPTQDTFR WNKGSLVMSN SSSHRGPGSP GGVVLEKHKT LKSVGNLSIG
660
STASMATTVG RKEFNRFV
Length:668
Mass (Da):74,282
Last modified:October 1, 2002 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i98456CD41AD79B2E
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There is 1 potential isoform mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
B3H4F6B3H4F6_ARATH
IQ-domain 14
IQD14 IQ-domain 14, At2g43680, F18O19.21
669Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

<p>This subsection of the 'Sequence' section reports difference(s) between the protein sequence shown in the UniProtKB entry and other available protein sequences derived from the same gene.<p><a href='/help/sequence_caution' target='_top'>More...</a></p>Sequence cautioni

The sequence AAB64038 differs from that shown. Reason: Erroneous gene model prediction.Curated

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AC002333 Genomic DNA Translation: AAB64038.1 Sequence problems.
CP002685 Genomic DNA Translation: AEC10305.1
CP002685 Genomic DNA Translation: AEC10307.1
CP002685 Genomic DNA Translation: ANM62407.1
CP002685 Genomic DNA Translation: ANM62408.1
AY099822 mRNA Translation: AAM20673.1
BT008408 mRNA Translation: AAP37767.1
AK226517 mRNA Translation: BAE98657.1

Protein sequence database of the Protein Information Resource

More...
PIRi
B84869

NCBI Reference Sequences

More...
RefSeqi
NP_001154574.1, NM_001161102.2 [Q8LPG9-1]
NP_001318416.1, NM_001337049.1 [Q8LPG9-1]
NP_001324566.1, NM_001337050.1 [Q8LPG9-1]
NP_973681.2, NM_201952.2 [Q8LPG9-1]

Genome annotation databases

Ensembl plant genome annotation project

More...
EnsemblPlantsi
AT2G43680.2; AT2G43680.2; AT2G43680 [Q8LPG9-1]
AT2G43680.3; AT2G43680.3; AT2G43680 [Q8LPG9-1]
AT2G43680.4; AT2G43680.4; AT2G43680 [Q8LPG9-1]
AT2G43680.5; AT2G43680.5; AT2G43680 [Q8LPG9-1]

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
818970

Gramene; a comparative resource for plants

More...
Gramenei
AT2G43680.2; AT2G43680.2; AT2G43680 [Q8LPG9-1]
AT2G43680.3; AT2G43680.3; AT2G43680 [Q8LPG9-1]
AT2G43680.4; AT2G43680.4; AT2G43680 [Q8LPG9-1]
AT2G43680.5; AT2G43680.5; AT2G43680 [Q8LPG9-1]

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
ath:AT2G43680

Keywords - Coding sequence diversityi

Alternative splicing

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC002333 Genomic DNA Translation: AAB64038.1 Sequence problems.
CP002685 Genomic DNA Translation: AEC10305.1
CP002685 Genomic DNA Translation: AEC10307.1
CP002685 Genomic DNA Translation: ANM62407.1
CP002685 Genomic DNA Translation: ANM62408.1
AY099822 mRNA Translation: AAM20673.1
BT008408 mRNA Translation: AAP37767.1
AK226517 mRNA Translation: BAE98657.1
PIRiB84869
RefSeqiNP_001154574.1, NM_001161102.2 [Q8LPG9-1]
NP_001318416.1, NM_001337049.1 [Q8LPG9-1]
NP_001324566.1, NM_001337050.1 [Q8LPG9-1]
NP_973681.2, NM_201952.2 [Q8LPG9-1]

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

Protein-protein interaction databases

BioGRIDi4306, 2 interactors
STRINGi3702.AT2G43680.1

PTM databases

iPTMnetiQ8LPG9

Proteomic databases

PaxDbiQ8LPG9
PRIDEiQ8LPG9
ProteomicsDBi228832 [Q8LPG9-1]

Genome annotation databases

EnsemblPlantsiAT2G43680.2; AT2G43680.2; AT2G43680 [Q8LPG9-1]
AT2G43680.3; AT2G43680.3; AT2G43680 [Q8LPG9-1]
AT2G43680.4; AT2G43680.4; AT2G43680 [Q8LPG9-1]
AT2G43680.5; AT2G43680.5; AT2G43680 [Q8LPG9-1]
GeneIDi818970
GrameneiAT2G43680.2; AT2G43680.2; AT2G43680 [Q8LPG9-1]
AT2G43680.3; AT2G43680.3; AT2G43680 [Q8LPG9-1]
AT2G43680.4; AT2G43680.4; AT2G43680 [Q8LPG9-1]
AT2G43680.5; AT2G43680.5; AT2G43680 [Q8LPG9-1]
KEGGiath:AT2G43680

Organism-specific databases

AraportiAT2G43680

Phylogenomic databases

eggNOGiENOG502R9C0, Eukaryota
HOGENOMiCLU_025762_0_0_1
InParanoidiQ8LPG9
PhylomeDBiQ8LPG9

Miscellaneous databases

Protein Ontology

More...
PROi
PR:Q8LPG9

Gene expression databases

ExpressionAtlasiQ8LPG9, baseline and differential
GenevisibleiQ8LPG9, AT

Family and domain databases

InterProiView protein in InterPro
IPR025064, DUF4005
IPR000048, IQ_motif_EF-hand-BS
PfamiView protein in Pfam
PF13178, DUF4005, 1 hit
PF00612, IQ, 1 hit
SMARTiView protein in SMART
SM00015, IQ, 1 hit
PROSITEiView protein in PROSITE
PS50096, IQ, 2 hits

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiIQD14_ARATH
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q8LPG9
Secondary accession number(s): O22835
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: November 13, 2007
Last sequence update: October 1, 2002
Last modified: August 12, 2020
This is version 93 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. Arabidopsis thaliana
    Arabidopsis thaliana: entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.

Do not show this banner again