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UniProtKB - Q8LNV6 (CKX3_ORYSJ)
Protein
Cytokinin dehydrogenase 3
Gene
CKX3
Organism
Oryza sativa subsp. japonica (Rice)
Status
Functioni
Catalyzes the oxidation of cytokinins, a family of N6-substituted adenine derivatives that are plant hormones, where the substituent is an isopentenyl group.
By similarityCatalytic activityi
- EC:1.5.99.12
Cofactori
FADBy similarity
Sites
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Binding sitei | 97 | FAD; via carbonyl oxygenBy similarity | 1 | |
Binding sitei | 155 | FAD; via amide nitrogenBy similarity | 1 | |
Binding sitei | 160 | FADBy similarity | 1 | |
Binding sitei | 221 | FAD; via amide nitrogen and carbonyl oxygenBy similarity | 1 | |
Binding sitei | 471 | FADBy similarity | 1 |
Regions
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Nucleotide bindingi | 87 – 91 | FADBy similarity | 5 | |
Nucleotide bindingi | 92 – 93 | FADBy similarity | 2 | |
Nucleotide bindingi | 166 – 170 | FADBy similarity | 5 | |
Nucleotide bindingi | 506 – 509 | FADBy similarity | 4 |
GO - Molecular functioni
- cytokinin dehydrogenase activity Source: Gramene
- FAD binding Source: InterPro
- oxidoreductase activity Source: GO_Central
GO - Biological processi
- cytokinin metabolic process Source: InterPro
Keywordsi
Molecular function | Oxidoreductase |
Ligand | FAD, Flavoprotein |
Names & Taxonomyi
Protein namesi | Recommended name: Cytokinin dehydrogenase 3 (EC:1.5.99.12)Alternative name(s): Cytokinin oxidase 3 Short name: OsCKX3 |
Gene namesi | Name:CKX3 Ordered Locus Names:Os10g0483500, LOC_Os10g34230 ORF Names:OsJ_31929, OsJ_35246, OSJNBa0012L23.33 |
Organismi | Oryza sativa subsp. japonica (Rice) |
Taxonomic identifieri | 39947 [NCBI] |
Taxonomic lineagei | Eukaryota › Viridiplantae › Streptophyta › Embryophyta › Tracheophyta › Spermatophyta › Magnoliopsida › Liliopsida › Poales › Poaceae › BOP clade › Oryzoideae › Oryzeae › Oryzinae › Oryza › Oryza sativa |
Proteomesi |
|
Subcellular locationi
Extracellular region or secreted
- extracellular space By similarity
Extracellular region or secreted
- extracellular space Source: UniProtKB-SubCell
Keywords - Cellular componenti
SecretedPTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Signal peptidei | 1 – 22 | Sequence analysisAdd BLAST | 22 | |
ChainiPRO_0000394206 | 23 – 527 | Cytokinin dehydrogenase 3Add BLAST | 505 |
Amino acid modifications
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Modified residuei | 92 | Pros-8alpha-FAD histidineBy similarity | 1 | |
Glycosylationi | 413 | N-linked (GlcNAc...) asparagineSequence analysis | 1 |
Keywords - PTMi
GlycoproteinProteomic databases
PaxDbi | Q8LNV6 |
Expressioni
Tissue specificityi
Expressed in inflorescence meristems.1 Publication
Gene expression databases
Genevisiblei | Q8LNV6, OS |
Interactioni
Subunit structurei
Monomer.
By similarityProtein-protein interaction databases
STRINGi | 4530.OS10T0483500-01 |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 52 – 231 | FAD-binding PCMH-typePROSITE-ProRule annotationAdd BLAST | 180 |
Sequence similaritiesi
Belongs to the oxygen-dependent FAD-linked oxidoreductase family.Curated
Keywords - Domaini
SignalPhylogenomic databases
eggNOGi | KOG1231, Eukaryota |
HOGENOMi | CLU_024955_1_0_1 |
InParanoidi | Q8LNV6 |
OMAi | VISRQMS |
OrthoDBi | 733611at2759 |
Family and domain databases
Gene3Di | 3.30.43.10, 1 hit 3.30.465.10, 1 hit 3.40.462.10, 1 hit |
InterProi | View protein in InterPro IPR016170, Cytok_DH_C_sf IPR015345, Cytokinin_DH_FAD/cytokin-bd IPR016166, FAD-bd_PCMH IPR036318, FAD-bd_PCMH-like_sf IPR016167, FAD-bd_PCMH_sub1 IPR016169, FAD-bd_PCMH_sub2 IPR016164, FAD-linked_Oxase-like_C IPR006094, Oxid_FAD_bind_N |
Pfami | View protein in Pfam PF09265, Cytokin-bind, 1 hit PF01565, FAD_binding_4, 1 hit |
SUPFAMi | SSF55103, SSF55103, 1 hit SSF56176, SSF56176, 1 hit |
PROSITEi | View protein in PROSITE PS51387, FAD_PCMH, 1 hit |
i Sequence
Sequence statusi: Complete.
: The displayed sequence is further processed into a mature form. Sequence processingi
Q8LNV6-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MEVAMVCTRV NLLILILSLC SPYKFIQSPM DFGPLNLLPT TTTASSDFGR
60 70 80 90 100
ILFHSPSAVL KPQAPRDISL LLSFLSASPL GKVTVAARGA GHSIHGQAQA
110 120 130 140 150
LDGIVVEMSS LPSEIEFYRR GEGDVSYADV GGGIMWIELL EQSLKLGLAP
160 170 180 190 200
RSWTDYLYLT IGGTLSNAGI SGQTFKHGPQ ISNVLQLEVV TGRGEIVTCS
210 220 230 240 250
PTKDAELFNA VLGGLGQFGI ITRARILLQE APQKVKWVRA FYDDFATFTK
260 270 280 290 300
DQELLVSMPV LVDYVEGFIV LNEQSLHSSS IAFPTNVDFN PDFGTKNNPK
310 320 330 340 350
IYYCIEFAVH DYQNKNINVE QVVEVISRQM SHIASHLYSV EVSYFDFLNR
360 370 380 390 400
VRMEEMSLRN SGLWEVHHPW LNMFVPSAGI SDFRDLLMDS ISPDNFEGLI
410 420 430 440 450
LIYPLLRHKW DTNTSVVLPD SGSTDQVMYA VGILRSANPD DGCSHHCLQE
460 470 480 490 500
LLLRHRRLAG AAASGLGAKQ YLAHHPTPAG WRRHFGRRWE RFADRKARFD
510 520
PRCILGPGQG IFPRDSSSSN GAFASYS
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AC051632 Genomic DNA Translation: AAM91887.1 DP000086 Genomic DNA Translation: AAP54326.1 AP008216 Genomic DNA Translation: BAF26800.1 AP014966 Genomic DNA Translation: BAT11359.1 CM000147 Genomic DNA Translation: EAZ16460.1 CM000149 Genomic DNA Translation: EAZ19670.1 AK103272 mRNA Translation: BAG95988.1 |
RefSeqi | XP_015613042.1, XM_015757556.1 XP_015613043.1, XM_015757557.1 XP_015613045.1, XM_015757559.1 XP_015613046.1, XM_015757560.1 |
Genome annotation databases
EnsemblPlantsi | Os10t0483500-01; Os10t0483500-01; Os10g0483500 |
GeneIDi | 4348932 |
Gramenei | Os10t0483500-01; Os10t0483500-01; Os10g0483500 |
KEGGi | osa:4348932 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AC051632 Genomic DNA Translation: AAM91887.1 DP000086 Genomic DNA Translation: AAP54326.1 AP008216 Genomic DNA Translation: BAF26800.1 AP014966 Genomic DNA Translation: BAT11359.1 CM000147 Genomic DNA Translation: EAZ16460.1 CM000149 Genomic DNA Translation: EAZ19670.1 AK103272 mRNA Translation: BAG95988.1 |
RefSeqi | XP_015613042.1, XM_015757556.1 XP_015613043.1, XM_015757557.1 XP_015613045.1, XM_015757559.1 XP_015613046.1, XM_015757560.1 |
3D structure databases
SMRi | Q8LNV6 |
ModBasei | Search... |
Protein-protein interaction databases
STRINGi | 4530.OS10T0483500-01 |
Proteomic databases
PaxDbi | Q8LNV6 |
Genome annotation databases
EnsemblPlantsi | Os10t0483500-01; Os10t0483500-01; Os10g0483500 |
GeneIDi | 4348932 |
Gramenei | Os10t0483500-01; Os10t0483500-01; Os10g0483500 |
KEGGi | osa:4348932 |
Phylogenomic databases
eggNOGi | KOG1231, Eukaryota |
HOGENOMi | CLU_024955_1_0_1 |
InParanoidi | Q8LNV6 |
OMAi | VISRQMS |
OrthoDBi | 733611at2759 |
Gene expression databases
Genevisiblei | Q8LNV6, OS |
Family and domain databases
Gene3Di | 3.30.43.10, 1 hit 3.30.465.10, 1 hit 3.40.462.10, 1 hit |
InterProi | View protein in InterPro IPR016170, Cytok_DH_C_sf IPR015345, Cytokinin_DH_FAD/cytokin-bd IPR016166, FAD-bd_PCMH IPR036318, FAD-bd_PCMH-like_sf IPR016167, FAD-bd_PCMH_sub1 IPR016169, FAD-bd_PCMH_sub2 IPR016164, FAD-linked_Oxase-like_C IPR006094, Oxid_FAD_bind_N |
Pfami | View protein in Pfam PF09265, Cytokin-bind, 1 hit PF01565, FAD_binding_4, 1 hit |
SUPFAMi | SSF55103, SSF55103, 1 hit SSF56176, SSF56176, 1 hit |
PROSITEi | View protein in PROSITE PS51387, FAD_PCMH, 1 hit |
MobiDBi | Search... |
Entry informationi
Entry namei | CKX3_ORYSJ | |
Accessioni | Q8LNV6Primary (citable) accession number: Q8LNV6 Secondary accession number(s): A0A0P0XVJ7, A3CF07 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | May 18, 2010 |
Last sequence update: | October 1, 2002 | |
Last modified: | February 23, 2022 | |
This is version 117 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Plant Protein Annotation Program |
Miscellaneousi
Keywords - Technical termi
Reference proteomeDocuments
- Oryza sativa (rice)
Index of Oryza sativa entries and their corresponding gene designations - SIMILARITY comments
Index of protein domains and families