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Protein

Cyclic dof factor 3

Gene

CDF3

Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Transcription factor that binds specifically to a 5'-AA[AG]G-3' consensus core sequence (By similarity). Regulates a photoperiodic flowering response. Transcriptional repressor of 'CONSTANS' expression.By similarity1 Publication

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Function’ section specifies the position(s) and type(s) of zinc fingers within the protein.<p><a href='/help/zn_fing' target='_top'>More...</a></p>Zinc fingeri110 – 164Dof-typePROSITE-ProRule annotationAdd BLAST55

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

  • DNA binding Source: GO_Central
  • DNA-binding transcription factor activity Source: TAIR
  • metal ion binding Source: UniProtKB-KW
  • sequence-specific DNA binding Source: GO_Central

GO - Biological processi

  • flower development Source: UniProtKB-KW
  • regulation of transcription, DNA-templated Source: TAIR

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionDNA-binding
Biological processFlowering, Transcription, Transcription regulation
LigandMetal-binding, Zinc

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Cyclic dof factor 3
Alternative name(s):
Dof zinc finger protein DOF3.3
Short name:
AtDOF3.3
H-protein promoter-binding factor 2a
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:CDF3
Synonyms:DOF3.3, HPPBF-2A
Ordered Locus Names:At3g47500
ORF Names:F1P2.50
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiArabidopsis thaliana (Mouse-ear cress)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri3702 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000006548 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 3

Organism-specific databases

Arabidopsis Information Portal

More...
Araporti
AT3G47500

The Arabidopsis Information Resource

More...
TAIRi
locus:2079152 AT3G47500

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Chloroplast Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertion Graphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Nucleus

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

<p>This subsection of the ‘Pathology and Biotech’ section describes the in vivo effects caused by ablation of the gene (or one or more transcripts) coding for the protein described in the entry. This includes gene knockout and knockdown, provided experiments have been performed in the context of a whole organism or a specific tissue, and not at the single-cell level.<p><a href='/help/disruption_phenotype' target='_top'>More...</a></p>Disruption phenotypei

No alteration in flowering time, probably due to the redundancy with CDF1, CDF2 and CDF5.1 Publication

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00000742791 – 448Cyclic dof factor 3Add BLAST448

Proteomic databases

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q8LFV3

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
Q8LFV3

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

<p>This subsection of the ‘Expression’ section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms. By default, the information is derived from experiments at the mRNA level, unless specified ‘at protein level’. <br></br>Examples: <a href="http://www.uniprot.org/uniprot/P92958#expression">P92958</a>, <a href="http://www.uniprot.org/uniprot/Q8TDN4#expression">Q8TDN4</a>, <a href="http://www.uniprot.org/uniprot/O14734#expression">O14734</a><p><a href='/help/tissue_specificity' target='_top'>More...</a></p>Tissue specificityi

Expressed in the vasculature of cotyledons and hypocotyls, leaves and roots.1 Publication

<p>This subsection of the ‘Expression’ section reports the experimentally proven effects of inducers and repressors (usually chemical compounds or environmental factors) on the level of protein (or mRNA) expression (up-regulation, down-regulation, constitutive expression).<p><a href='/help/induction' target='_top'>More...</a></p>Inductioni

Circadian-regulation. Highly expressed at the beginning of the light period, then decreases, reaching a minimum between 16 and 29 hours after dawn before rising again at the end of the day.1 Publication

Gene expression databases

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
Q8LFV3 baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
Q8LFV3 AT

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction_section">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function_section">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

Interacts with ADO2 (via kelch repeats) and ADO3 (via kelch repeats).1 Publication

<p>This subsection of the '<a href="http://www.uniprot.org/help/interaction_section%27">Interaction</a> section provides information about binary protein-protein interactions. The data presented in this section are a quality-filtered subset of binary interactions automatically derived from the <a href="http://www.ebi.ac.uk/intact/">IntAct database</a>. It is updated on a monthly basis. Each binary interaction is displayed on a separate line.<p><a href='/help/binary_interactions' target='_top'>More...</a></p>Binary interactionsi

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGrid)

More...
BioGridi
9224, 2 interactors

Protein interaction database and analysis system

More...
IntActi
Q8LFV3, 2 interactors

STRING: functional protein association networks

More...
STRINGi
3702.AT3G47500.1

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi291 – 329Pro-richAdd BLAST39

Zinc finger

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Zinc fingeri110 – 164Dof-typePROSITE-ProRule annotationAdd BLAST55

Keywords - Domaini

Zinc-finger

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
ENOG410IIJ7 Eukaryota
ENOG410YN7N LUCA

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
HOG000239772

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q8LFV3

Identification of Orthologs from Complete Genome Data

More...
OMAi
NHSVDES

Database of Orthologous Groups

More...
OrthoDBi
EOG0936092V

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q8LFV3

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR003851 Znf_Dof

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF02701 zf-Dof, 1 hit

ProDom; a protein domain database

More...
ProDomi
View protein in ProDom or Entries sharing at least one domain
PD007478 Znf_Dof, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS01361 ZF_DOF_1, 1 hit
PS50884 ZF_DOF_2, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>.<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

Q8LFV3-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MMMETRDPAI KLFGMKIPFP SVFESAVTVE DDEEDDWSGG DDKSPEKVTP
60 70 80 90 100
ELSDKNNNNC NDNSFNNSKP ETLDKEEATS TDQIESSDTP EDNQQTTPDG
110 120 130 140 150
KTLKKPTKIL PCPRCKSMET KFCYYNNYNI NQPRHFCKAC QRYWTAGGTM
160 170 180 190 200
RNVPVGAGRR KNKSSSSHYR HITISEALEA ARLDPGLQAN TRVLSFGLEA
210 220 230 240 250
QQQHVAAPMT PVMKLQEDQK VSNGARNRFH GLADQRLVAR VENGDDCSSG
260 270 280 290 300
SSVTTSNNHS VDESRAQSGS VVEAQMNNNN NNNMNGYACI PGVPWPYTWN
310 320 330 340 350
PAMPPPGFYP PPGYPMPFYP YWTIPMLPPH QSSSPISQKC SNTNSPTLGK
360 370 380 390 400
HPRDEGSSKK DNETERKQKA GCVLVPKTLR IDDPNEAAKS SIWTTLGIKN
410 420 430 440
EAMCKAGGMF KGFDHKTKMY NNDKAENSPV LSANPAALSR SHNFHEQI
Length:448
Mass (Da):49,730
Last modified:October 25, 2004 - v2
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i6E61FA7A7A8DF1F6
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti88D → E in AAM61191 (Ref. 5) Curated1
Sequence conflicti201Q → H in AAM61191 (Ref. 5) Curated1
Sequence conflicti206Missing in AAM61191 (Ref. 5) Curated1
Sequence conflicti210T → A in AAM61191 (Ref. 5) Curated1
Sequence conflicti217E → G in AAM61191 (Ref. 5) Curated1
Sequence conflicti228R → G in AAM61191 (Ref. 5) Curated1
Sequence conflicti270 – 271SV → RI in AAM61191 (Ref. 5) Curated2
Sequence conflicti274A → P in AAM61191 (Ref. 5) Curated1
Sequence conflicti277 – 278Missing in AAM61191 (Ref. 5) Curated2
Sequence conflicti327 – 328LP → ISPS in AAM61191 (Ref. 5) Curated2
Sequence conflicti340C → D in AAM61191 (Ref. 5) Curated1
Sequence conflicti351 – 352HP → RS in AAM61191 (Ref. 5) Curated2
Sequence conflicti356G → E in AAM61191 (Ref. 5) Curated1
Sequence conflicti360 – 362KDN → RDS in AAM61191 (Ref. 5) Curated3
Sequence conflicti369 – 370KA → RT in AAM61191 (Ref. 5) Curated2
Sequence conflicti373V → I in AAM61191 (Ref. 5) Curated1

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AF079503 mRNA Translation: AAC28390.1
AL132955 Genomic DNA Translation: CAB61976.1
CP002686 Genomic DNA Translation: AEE78290.1
AY065152 mRNA Translation: AAL38328.1
AY128757 mRNA Translation: AAM91157.1
AY084628 mRNA Translation: AAM61191.1

Protein sequence database of the Protein Information Resource

More...
PIRi
T45710

NCBI Reference Sequences

More...
RefSeqi
NP_190334.1, NM_114618.4

UniGene gene-oriented nucleotide sequence clusters

More...
UniGenei
At.519

Genome annotation databases

Ensembl plant genome annotation project

More...
EnsemblPlantsi
AT3G47500.1; AT3G47500.1; AT3G47500

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
823904

Gramene; a comparative resource for plants

More...
Gramenei
AT3G47500.1; AT3G47500.1; AT3G47500

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
ath:AT3G47500

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF079503 mRNA Translation: AAC28390.1
AL132955 Genomic DNA Translation: CAB61976.1
CP002686 Genomic DNA Translation: AEE78290.1
AY065152 mRNA Translation: AAL38328.1
AY128757 mRNA Translation: AAM91157.1
AY084628 mRNA Translation: AAM61191.1
PIRiT45710
RefSeqiNP_190334.1, NM_114618.4
UniGeneiAt.519

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

Protein-protein interaction databases

BioGridi9224, 2 interactors
IntActiQ8LFV3, 2 interactors
STRINGi3702.AT3G47500.1

PTM databases

iPTMnetiQ8LFV3

Proteomic databases

PaxDbiQ8LFV3

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblPlantsiAT3G47500.1; AT3G47500.1; AT3G47500
GeneIDi823904
GrameneiAT3G47500.1; AT3G47500.1; AT3G47500
KEGGiath:AT3G47500

Organism-specific databases

AraportiAT3G47500
TAIRilocus:2079152 AT3G47500

Phylogenomic databases

eggNOGiENOG410IIJ7 Eukaryota
ENOG410YN7N LUCA
HOGENOMiHOG000239772
InParanoidiQ8LFV3
OMAiNHSVDES
OrthoDBiEOG0936092V
PhylomeDBiQ8LFV3

Miscellaneous databases

Protein Ontology

More...
PROi
PR:Q8LFV3

Gene expression databases

ExpressionAtlasiQ8LFV3 baseline and differential
GenevisibleiQ8LFV3 AT

Family and domain databases

InterProiView protein in InterPro
IPR003851 Znf_Dof
PfamiView protein in Pfam
PF02701 zf-Dof, 1 hit
ProDomiView protein in ProDom or Entries sharing at least one domain
PD007478 Znf_Dof, 1 hit
PROSITEiView protein in PROSITE
PS01361 ZF_DOF_1, 1 hit
PS50884 ZF_DOF_2, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiCDF3_ARATH
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q8LFV3
Secondary accession number(s): O81600
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: October 25, 2004
Last sequence update: October 25, 2004
Last modified: November 7, 2018
This is version 101 of the entry and version 2 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Arabidopsis thaliana
    Arabidopsis thaliana: entries and gene names
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