Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Entry version 125 (29 Sep 2021)
Sequence version 1 (01 Oct 2002)
Previous versions | rss
Add a publicationFeedback
Protein

50S ribosomal protein L21, mitochondrial

Gene

RPL21M

Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

This protein binds to 23S ribosomal RNA in the presence of protein L20 (By similarity).

Required for karyogamy during female gametophyte development, when the two polar nuclei fuse to form the diploid central cell nucleus, and during double fertilization of the egg cell and the central cell (PubMed:16698901).

By similarity1 Publication

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionDevelopmental protein, Ribonucleoprotein, Ribosomal protein, RNA-binding, rRNA-binding
Biological processFertilization, Karyogamy

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
50S ribosomal protein L21, mitochondrial1 Publication
Alternative name(s):
Protein NUCLEAR FUSION DEFECTIVE 11 Publication
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:RPL21M1 Publication
Synonyms:NFD11 Publication
Ordered Locus Names:At4g30930Imported
ORF Names:F6I18.160
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiArabidopsis thaliana (Mouse-ear cress)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri3702 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliopsidaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000006548 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 4

Organism-specific databases

Arabidopsis Information Portal

More...
Araporti
AT4G30930

The Arabidopsis Information Resource

More...
TAIRi
locus:2126699, AT4G30930

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Keywords - Cellular componenti

Mitochondrion

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

<p>This subsection of the 'Pathology and Biotech' section describes the in vivo effects caused by ablation of the gene (or one or more transcripts) coding for the protein described in the entry. This includes gene knockout and knockdown, provided experiments have been performed in the context of a whole organism or a specific tissue, and not at the single-cell level.<p><a href='/help/disruption_phenotype' target='_top'>More...</a></p>Disruption phenotypei

Failure of fusion of the polar nuclei during megagametogenesis and abnormal double fertilization; fails to undergo fusion of the outer nuclear membranes.1 Publication

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a transit peptide.<p><a href='/help/transit' target='_top'>More...</a></p>Transit peptidei1 – 68MitochondrionSequence analysisAdd BLAST68
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_000003048269 – 27050S ribosomal protein L21, mitochondrialAdd BLAST202

Proteomic databases

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q8L9A0

PRoteomics IDEntifications database

More...
PRIDEi
Q8L9A0

ProteomicsDB: a multi-organism proteome resource

More...
ProteomicsDBi
228176

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
Q8L9A0

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

<p>This subsection of the 'Expression' section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms. By default, the information is derived from experiments at the mRNA level, unless specified 'at protein level'.<br></br>Examples: <a href="http://www.uniprot.org/uniprot/P92958#expression">P92958</a>, <a href="http://www.uniprot.org/uniprot/Q8TDN4#expression">Q8TDN4</a>, <a href="http://www.uniprot.org/uniprot/O14734#expression">O14734</a><p><a href='/help/tissue_specificity' target='_top'>More...</a></p>Tissue specificityi

Constitutively expressed in roots, stems, leaves, flowers, pistils and siliques.2 Publications

Gene expression databases

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
Q8L9A0, baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
Q8L9A0, AT

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGRID)

More...
BioGRIDi
14504, 5 interactors

Protein interaction database and analysis system

More...
IntActi
Q8L9A0, 2 interactors

STRING: functional protein association networks

More...
STRINGi
3702.AT4G30930.1

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

Protein Data Bank in Europe - Knowledge Base

More...
PDBe-KBi
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni68 – 113DisorderedSequence analysisAdd BLAST46

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes the position of regions of compositional bias within the protein and the particular type of amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi76 – 101Acidic residuesSequence analysisAdd BLAST26

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Keywords - Domaini

Transit peptide

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG1686, Eukaryota

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
CLU_061463_4_0_1

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q8L9A0

Identification of Orthologs from Complete Genome Data

More...
OMAi
SRRAMTV

Database of Orthologous Groups

More...
OrthoDBi
1586807at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q8L9A0

Family and domain databases

HAMAP database of protein families

More...
HAMAPi
MF_01363, Ribosomal_L21, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR036164, L21-like_sf
IPR028909, L21p-like
IPR001787, Ribosomal_L21
IPR018258, Ribosomal_L21_CS

The PANTHER Classification System

More...
PANTHERi
PTHR21349, PTHR21349, 1 hit

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF00829, Ribosomal_L21p, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF141091, SSF141091, 1 hit

TIGRFAMs; a protein family database

More...
TIGRFAMsi
TIGR00061, L21, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS01169, RIBOSOMAL_L21, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is in its mature form or if it represents the precursor.<p><a href='/help/sequence_processing' target='_top'>More...</a></p>Sequence processingi: The displayed sequence is further processed into a mature form.

Q8L9A0-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MASLRCFREL SRRATTVFSI NQTRSISSFH GIEFSGTSIS HGTVIPNRSL
60 70 80 90 100
TRNLPWYSHW YRSQDRCFSS NTKDTDEDEE SSEGEDDDEE EGEDFEDSAD
110 120 130 140 150
MEVEREYSPA EKVEEAEEIG YKVMGPLKPS ERLFKPYEPV FAIVQIGSHQ
160 170 180 190 200
FKVSNGDSIF TEKLKFCDIN DKLELTKVLL LGSASQTIIG RPILPDATVH
210 220 230 240 250
AVVEEHALDE KVLIFKKKRR KNYRRTRGHR QELTKLRITD IQGIEKPEPK
260 270
IVHKPSKEAV TEQTKAELVA
Length:270
Mass (Da):30,908
Last modified:October 1, 2002 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iC83E96E95666ABF9
GO

<p>This subsection of the 'Sequence' section reports difference(s) between the protein sequence shown in the UniProtKB entry and other available protein sequences derived from the same gene.<p><a href='/help/sequence_caution' target='_top'>More...</a></p>Sequence cautioni

The sequence CAA18200 differs from that shown. Reason: Erroneous gene model prediction. The predicted gene At4g30930 has been split into 2 genes: At4g30930 and At4g30935.Curated
The sequence CAB79811 differs from that shown. Reason: Erroneous gene model prediction. The predicted gene At4g30930 has been split into 2 genes: At4g30930 and At4g30935.Curated

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AJ278909 Genomic DNA Translation: CAC27453.1
AL022198 Genomic DNA Translation: CAA18200.1 Sequence problems.
AL161578 Genomic DNA Translation: CAB79811.1 Sequence problems.
CP002687 Genomic DNA Translation: AEE85831.1
BT005870 mRNA Translation: AAO64805.1
AK228212 mRNA Translation: BAF00165.1
AY088563 mRNA Translation: AAM66095.1
AB493710 mRNA Translation: BAH30548.1

Protein sequence database of the Protein Information Resource

More...
PIRi
B85362

NCBI Reference Sequences

More...
RefSeqi
NP_567861.1, NM_119240.4

Genome annotation databases

Ensembl plant genome annotation project

More...
EnsemblPlantsi
AT4G30930.1; AT4G30930.1; AT4G30930

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
829217

Gramene; a comparative resource for plants

More...
Gramenei
AT4G30930.1; AT4G30930.1; AT4G30930

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
ath:AT4G30930

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AJ278909 Genomic DNA Translation: CAC27453.1
AL022198 Genomic DNA Translation: CAA18200.1 Sequence problems.
AL161578 Genomic DNA Translation: CAB79811.1 Sequence problems.
CP002687 Genomic DNA Translation: AEE85831.1
BT005870 mRNA Translation: AAO64805.1
AK228212 mRNA Translation: BAF00165.1
AY088563 mRNA Translation: AAM66095.1
AB493710 mRNA Translation: BAH30548.1
PIRiB85362
RefSeqiNP_567861.1, NM_119240.4

3D structure databases

Select the link destinations:

Protein Data Bank Europe

More...
PDBei

Protein Data Bank RCSB

More...
RCSB PDBi

Protein Data Bank Japan

More...
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
6XYWelectron microscopy3.86Ar1-270[»]
ModBaseiSearch...
SWISS-MODEL-WorkspaceiSubmit a new modelling project...
PDBe-KBiSearch...

Protein-protein interaction databases

BioGRIDi14504, 5 interactors
IntActiQ8L9A0, 2 interactors
STRINGi3702.AT4G30930.1

PTM databases

iPTMnetiQ8L9A0

Proteomic databases

PaxDbiQ8L9A0
PRIDEiQ8L9A0
ProteomicsDBi228176

Genome annotation databases

EnsemblPlantsiAT4G30930.1; AT4G30930.1; AT4G30930
GeneIDi829217
GrameneiAT4G30930.1; AT4G30930.1; AT4G30930
KEGGiath:AT4G30930

Organism-specific databases

AraportiAT4G30930
TAIRilocus:2126699, AT4G30930

Phylogenomic databases

eggNOGiKOG1686, Eukaryota
HOGENOMiCLU_061463_4_0_1
InParanoidiQ8L9A0
OMAiSRRAMTV
OrthoDBi1586807at2759
PhylomeDBiQ8L9A0

Miscellaneous databases

Protein Ontology

More...
PROi
PR:Q8L9A0

Gene expression databases

ExpressionAtlasiQ8L9A0, baseline and differential
GenevisibleiQ8L9A0, AT

Family and domain databases

HAMAPiMF_01363, Ribosomal_L21, 1 hit
InterProiView protein in InterPro
IPR036164, L21-like_sf
IPR028909, L21p-like
IPR001787, Ribosomal_L21
IPR018258, Ribosomal_L21_CS
PANTHERiPTHR21349, PTHR21349, 1 hit
PfamiView protein in Pfam
PF00829, Ribosomal_L21p, 1 hit
SUPFAMiSSF141091, SSF141091, 1 hit
TIGRFAMsiTIGR00061, L21, 1 hit
PROSITEiView protein in PROSITE
PS01169, RIBOSOMAL_L21, 1 hit

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiRM21_ARATH
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q8L9A0
Secondary accession number(s): O65556, Q0WRT4, Q9B7N7
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: April 11, 2003
Last sequence update: October 1, 2002
Last modified: September 29, 2021
This is version 125 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

3D-structure, Reference proteome

Documents

  1. Ribosomal proteins
    Ribosomal proteins families and list of entries
  2. Arabidopsis thaliana
    Arabidopsis thaliana: entries and gene names
  3. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  4. SIMILARITY comments
    Index of protein domains and families
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.

Do not show this banner again