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UniProtKB - Q8L7R8 (STP3_ARATH)
Protein
Sugar transport protein 3
Gene
STP3
Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Functioni
Mediates an active uptake of hexoses, probably by sugar/hydrogen symport.
By similarityGO - Molecular functioni
- monosaccharide transmembrane transporter activity Source: InterPro
- symporter activity Source: UniProtKB-KW
Keywordsi
Biological process | Sugar transport, Symport, Transport |
Names & Taxonomyi
Protein namesi | Recommended name: Sugar transport protein 3Alternative name(s): Hexose transporter 3 |
Gene namesi | Name:STP3 Ordered Locus Names:At5g61520 ORF Names:K11J9_40 |
Organismi | Arabidopsis thaliana (Mouse-ear cress) |
Taxonomic identifieri | 3702 [NCBI] |
Taxonomic lineagei | Eukaryota › Viridiplantae › Streptophyta › Embryophyta › Tracheophyta › Spermatophyta › Magnoliopsida › eudicotyledons › Gunneridae › Pentapetalae › rosids › malvids › Brassicales › Brassicaceae › Camelineae › Arabidopsis |
Proteomesi |
|
Organism-specific databases
Araporti | AT5G61520 |
TAIRi | locus:2151596, AT5G61520 |
Subcellular locationi
Other locations
Other locations
- integral component of membrane Source: UniProtKB-KW
Topology
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Topological domaini | 1 – 19 | CytoplasmicSequence analysisAdd BLAST | 19 | |
Transmembranei | 20 – 40 | Helical; Name=1Sequence analysisAdd BLAST | 21 | |
Transmembranei | 87 – 107 | Helical; Name=2Sequence analysisAdd BLAST | 21 | |
Transmembranei | 124 – 144 | Helical; Name=3Sequence analysisAdd BLAST | 21 | |
Transmembranei | 147 – 167 | Helical; Name=4Sequence analysisAdd BLAST | 21 | |
Transmembranei | 174 – 194 | Helical; Name=5Sequence analysisAdd BLAST | 21 | |
Transmembranei | 207 – 227 | Helical; Name=6Sequence analysisAdd BLAST | 21 | |
Transmembranei | 289 – 309 | Helical; Name=7Sequence analysisAdd BLAST | 21 | |
Transmembranei | 327 – 347 | Helical; Name=8Sequence analysisAdd BLAST | 21 | |
Transmembranei | 356 – 376 | Helical; Name=9Sequence analysisAdd BLAST | 21 | |
Transmembranei | 392 – 412 | Helical; Name=10Sequence analysisAdd BLAST | 21 | |
Transmembranei | 430 – 450 | Helical; Name=11Sequence analysisAdd BLAST | 21 | |
Transmembranei | 456 – 476 | Helical; Name=12Sequence analysisAdd BLAST | 21 | |
Topological domaini | 477 – 514 | CytoplasmicSequence analysisAdd BLAST | 38 |
Keywords - Cellular componenti
MembranePTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
ChainiPRO_0000050433 | 1 – 514 | Sugar transport protein 3Add BLAST | 514 |
Proteomic databases
PaxDbi | Q8L7R8 |
PRIDEi | Q8L7R8 |
ProteomicsDBi | 228363 [Q8L7R8-1] |
PTM databases
iPTMneti | Q8L7R8 |
Expressioni
Gene expression databases
ExpressionAtlasi | Q8L7R8, baseline and differential |
Genevisiblei | Q8L7R8, AT |
Interactioni
Protein-protein interaction databases
BioGRIDi | 21517, 2 interactors |
IntActi | Q8L7R8, 2 interactors |
STRINGi | 3702.AT5G61520.1 |
Family & Domainsi
Sequence similaritiesi
Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. [View classification]Curated
Keywords - Domaini
Transmembrane, Transmembrane helixPhylogenomic databases
eggNOGi | KOG0254, Eukaryota |
HOGENOMi | CLU_001265_30_5_1 |
InParanoidi | Q8L7R8 |
OMAi | GITWKEC |
PhylomeDBi | Q8L7R8 |
Family and domain databases
CDDi | cd17361, MFS_STP, 1 hit |
Gene3Di | 1.20.1250.20, 1 hit |
InterProi | View protein in InterPro IPR020846, MFS_dom IPR044778, MFS_STP/MST-like_plant IPR005828, MFS_sugar_transport-like IPR036259, MFS_trans_sf IPR045262, STP/PLT_plant IPR003663, Sugar/inositol_transpt IPR005829, Sugar_transporter_CS |
PANTHERi | PTHR23500, PTHR23500, 1 hit |
Pfami | View protein in Pfam PF00083, Sugar_tr, 1 hit |
PRINTSi | PR00171, SUGRTRNSPORT |
SUPFAMi | SSF103473, SSF103473, 1 hit |
TIGRFAMsi | TIGR00879, SP, 1 hit |
PROSITEi | View protein in PROSITE PS50850, MFS, 1 hit PS00216, SUGAR_TRANSPORT_1, 1 hit PS00217, SUGAR_TRANSPORT_2, 1 hit |
s (2+)i Sequence
Sequence statusi: Complete.
This entry describes 2 produced by isoformsialternative splicing. AlignAdd to basketThis entry has 2 described isoforms and 1 potential isoform that is computationally mapped.Show allAlign All
Isoform 1 (identifier: Q8L7R8-1) [UniParc]FASTAAdd to basket
This isoform has been chosen as the sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry. canonicali
10 20 30 40 50
MVAEEARKEA MAKSVSGGKI TYFVVASCVM AAMGGVIFGY DIGVSGGVMS
60 70 80 90 100
MGPFLKRFFP KVYKLQEEDR RRRGNSNNHY CLFNSQLLTS FTSSLYVSGL
110 120 130 140 150
IATLLASSVT RSWGRKPSIF LGGVSFLAGA ALGGSAQNVA MLIIARLLLG
160 170 180 190 200
VGVGFANQSV PLYLSEMAPA KYRGAISNGF QLCIGIGFLS ANVINYETQN
210 220 230 240 250
IKHGWRISLA TAAIPASILT LGSLFLPETP NSIIQTTGDV HKTELMLRRV
260 270 280 290 300
RGTNDVQDEL TDLVEASSGS DTDSNAFLKL LQRKYRPELV MALVIPFFQQ
310 320 330 340 350
VTGINVVAFY APVLYRTVGF GESGSLMSTL VTGIVGTSST LLSMLVVDRI
360 370 380 390 400
GRKTLFLIGG LQMLVSQVTI GVIVMVADVH DGVIKEGYGY AVVVLVCVYV
410 420 430 440 450
AGFGWSWGPL GWLVPSEIFP LEIRSVAQSV TVAVSFVFTF AVAQSAPPML
460 470 480 490 500
CKFRAGIFFF YGGWLVVMTV AVQLFLPETK NVPIEKVVGL WEKHWFWRRM
510
TSKRDIQETT ILSH
Computationally mapped potential isoform sequencesi
There is 1 potential isoform mapped to this entry.BLASTAlignShow allAdd to basketF4K3I6 | F4K3I6_ARATH | Major facilitator superfamily prote... | At5g61520, K11J9.8, K11J9_8 | 466 | Annotation score: |
Alternative sequence
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Alternative sequenceiVSP_017028 | 1 – 166 | Missing in isoform 2. 1 PublicationAdd BLAST | 166 |
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AJ002399 mRNA Translation: CAA05384.1 AB012239 Genomic DNA Translation: BAB08997.1 CP002688 Genomic DNA Translation: AED97478.1 AY128303 mRNA Translation: AAM91109.1 BT000560 mRNA Translation: AAN18129.1 |
RefSeqi | NP_200960.2, NM_125545.4 [Q8L7R8-1] |
Genome annotation databases
EnsemblPlantsi | AT5G61520.1; AT5G61520.1; AT5G61520 [Q8L7R8-1] |
GeneIDi | 836273 |
Gramenei | AT5G61520.1; AT5G61520.1; AT5G61520 [Q8L7R8-1] |
KEGGi | ath:AT5G61520 |
Keywords - Coding sequence diversityi
Alternative splicingSimilar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AJ002399 mRNA Translation: CAA05384.1 AB012239 Genomic DNA Translation: BAB08997.1 CP002688 Genomic DNA Translation: AED97478.1 AY128303 mRNA Translation: AAM91109.1 BT000560 mRNA Translation: AAN18129.1 |
RefSeqi | NP_200960.2, NM_125545.4 [Q8L7R8-1] |
3D structure databases
AlphaFoldDBi | Q8L7R8 |
SMRi | Q8L7R8 |
ModBasei | Search... |
Protein-protein interaction databases
BioGRIDi | 21517, 2 interactors |
IntActi | Q8L7R8, 2 interactors |
STRINGi | 3702.AT5G61520.1 |
PTM databases
iPTMneti | Q8L7R8 |
Proteomic databases
PaxDbi | Q8L7R8 |
PRIDEi | Q8L7R8 |
ProteomicsDBi | 228363 [Q8L7R8-1] |
Genome annotation databases
EnsemblPlantsi | AT5G61520.1; AT5G61520.1; AT5G61520 [Q8L7R8-1] |
GeneIDi | 836273 |
Gramenei | AT5G61520.1; AT5G61520.1; AT5G61520 [Q8L7R8-1] |
KEGGi | ath:AT5G61520 |
Organism-specific databases
Araporti | AT5G61520 |
TAIRi | locus:2151596, AT5G61520 |
Phylogenomic databases
eggNOGi | KOG0254, Eukaryota |
HOGENOMi | CLU_001265_30_5_1 |
InParanoidi | Q8L7R8 |
OMAi | GITWKEC |
PhylomeDBi | Q8L7R8 |
Miscellaneous databases
PROi | PR:Q8L7R8 |
Gene expression databases
ExpressionAtlasi | Q8L7R8, baseline and differential |
Genevisiblei | Q8L7R8, AT |
Family and domain databases
CDDi | cd17361, MFS_STP, 1 hit |
Gene3Di | 1.20.1250.20, 1 hit |
InterProi | View protein in InterPro IPR020846, MFS_dom IPR044778, MFS_STP/MST-like_plant IPR005828, MFS_sugar_transport-like IPR036259, MFS_trans_sf IPR045262, STP/PLT_plant IPR003663, Sugar/inositol_transpt IPR005829, Sugar_transporter_CS |
PANTHERi | PTHR23500, PTHR23500, 1 hit |
Pfami | View protein in Pfam PF00083, Sugar_tr, 1 hit |
PRINTSi | PR00171, SUGRTRNSPORT |
SUPFAMi | SSF103473, SSF103473, 1 hit |
TIGRFAMsi | TIGR00879, SP, 1 hit |
PROSITEi | View protein in PROSITE PS50850, MFS, 1 hit PS00216, SUGAR_TRANSPORT_1, 1 hit PS00217, SUGAR_TRANSPORT_2, 1 hit |
MobiDBi | Search... |
Entry informationi
Entry namei | STP3_ARATH | |
Accessioni | Q8L7R8Primary (citable) accession number: Q8L7R8 Secondary accession number(s): Q9ZS56 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | January 24, 2006 |
Last sequence update: | January 24, 2006 | |
Last modified: | May 25, 2022 | |
This is version 124 of the entry and version 2 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Plant Protein Annotation Program |
Miscellaneousi
Keywords - Technical termi
Reference proteomeDocuments
- Arabidopsis thaliana
Arabidopsis thaliana: entries and gene names - SIMILARITY comments
Index of protein domains and families